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    • 5. 发明专利
    • Hyaluronidase activity inhibitor
    • HYALURONIDASE活性抑制剂
    • JP2007161646A
    • 2007-06-28
    • JP2005360377
    • 2005-12-14
    • Mikimoto Pharmaceut Co Ltd御木本製薬株式会社
    • ADACHI KATSUYOSHITADA TAKAHIROHAMAGUCHI MASANORIMATSUO YUKIMI
    • A61K8/97A61K36/18A61P17/16A61P29/00A61P43/00A61Q19/00
    • PROBLEM TO BE SOLVED: To find out an ingredient having a hyaluronidase inhibitory activity and to provide an external preparation for skin effective against dermatopathy caused by a hyaluronidase using the ingredient. SOLUTION: It is found that the problems can be solved by providing an external preparation for skin effective against the dermatopathy e.g. inflammations caused by the hyaluronidase, and comprising an extract from a plant belonging to the plants of the genus Hippophae of the family Elaeagnaceae as an active ingredient. In addition to the extract from the plant belonging to the plants of the genus Hippophae of the family Elaeagnaceae, one or two or more kinds selected from a humectant, a softener, a cell activator, an anti-inflammatory agent, an antioxidant, a blood circulation promoter and a bleaching agent are further formulated to thereby afford an effective preparation. COPYRIGHT: (C)2007,JPO&INPIT
    • 要解决的问题:找出具有透明质酸酶抑制活性的成分,并提供使用该成分由透明质酸酶引起的对皮肤病有效的皮肤外用制剂。 解决方案:发现问题可以通过提供皮肤有效的外用制剂来解决,例如皮肤病。 由透明质酸酶引起的炎症,并且包含来自属于耳科科的沙棘属植物的植物的提取物作为活性成分。 除了属于禾本科耳鼻喉科植物属植物的提取物之外,还有一种或两种以上选自湿润剂,软化剂,​​细胞活化剂,抗炎剂,抗氧化剂,血液 循环促进剂和漂白剂进一步配制,从而提供有效的制剂。 版权所有(C)2007,JPO&INPIT