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1. 发明申请

US20060191065A1 Portable toilet 有权
标题翻译：便携式厕所
公开(公告)号：US20060191065A1
公开(公告)日：2006-08-31
申请号：US11269425
申请日：2005-11-08
申请人： Miguel Martinez , Patrick Curran , Edward McKiernan , Otto Erbacher , Robert Krieder
发明人： Miguel Martinez , Patrick Curran , Edward McKiernan , Otto Erbacher , Robert Krieder
IPC分类号： E03D1/24
CPC分类号： E03D5/01
摘要： A portable toilet is provided comprising a bowl provided with an outlet and at least one spout. A flush tank is adapted to store a fluid, wherein the flush tank is adapted to be pressurized. A manually-actuated pump is in sealed communication with the flush tank, wherein the pump is adapted to cause the flush tank to become pressurized. A pressure relief valve adapted to release pressure from the flush tank. A manually-actuated flush valve is in sealed communication with the flush tank and is normally biased to a closed position. The flush valve includes a fluid outlet connected to the at least one spout and a fluid inlet. A flush valve actuator is disposed outside of the flush tank and is adapted to actuate the flush valve, wherein actuation of the flush valve actuator causes the flush valve to open to permit pressurized fluid contained within the flush tank to be delivered through the at least one spout.
摘要翻译：提供了一种便携式马桶，其包括设置有出口和至少一个喷口的碗。冲洗槽适于储存流体，其中冲洗罐适于加压。手动泵与冲洗水箱密封连通，其中泵适于使冲水箱加压。适于从冲洗槽释放压力的减压阀。手动冲洗阀与冲洗槽密封连通，通常被偏压到关闭位置。冲洗阀包括连接到至少一个喷口的流体出口和流体入口。冲洗阀致动器设置在冲洗槽的外部并且适于致动冲洗阀，其中冲洗阀致动器的致动导致冲洗阀打开以允许包含在冲洗罐内的加压流体通过至少一个喷口。

2. 发明申请

US20070117804A1 Imidazopyrazines as protein kinase inhibitors 审中-公开
标题翻译：咪唑吡嗪作为蛋白激酶抑制剂
公开(公告)号：US20070117804A1
公开(公告)日：2007-05-24
申请号：US11598186
申请日：2006-11-08
申请人： Lianyun Zhao , Patrick Curran , David Belanger , Blake Hamann , Panduranga Reddy , Kamil Paruch , Timothy Guzi , Michael Dwyer , M. Siddiqui , Praveen Tadikonda
发明人： Lianyun Zhao , Patrick Curran , David Belanger , Blake Hamann , Panduranga Reddy , Kamil Paruch , Timothy Guzi , Michael Dwyer , M. Siddiqui , Praveen Tadikonda
IPC分类号： A61K31/498 , C07D487/04
CPC分类号： C07D487/04
摘要： In its many embodiments, the present invention provides a novel class of imidazopyrazine compounds as inhibitors of protein and/or checkpoint kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or checkpoint kinases using such compounds or pharmaceutical compositions.
摘要翻译：在其许多实施方案中，本发明提供了一类新颖的咪唑并吡嗪化合物作为蛋白质和/或检查点激酶的抑制剂，制备此类化合物的方法，包含一种或多种此类化合物的药物组合物，制备药物制剂的方法，包括一种或多种化合物，以及使用这些化合物或药物组合物治疗，预防，抑制或改善与蛋白质或检查点激酶相关的一种或多种疾病的方法。

3. 发明授权

US11630624B1 Concurrent event detection for distributed rasterization processing in a printing environment 有权
公开(公告)号：US11630624B1
公开(公告)日：2023-04-18
申请号：US17693681
申请日：2022-03-14
申请人： Walter F. Kailey , Patrick Curran
发明人： Walter F. Kailey , Patrick Curran
IPC分类号： G06F3/12
摘要： Systems and methods are provided for event detection. One embodiment includes an interface that acquires logs, and a controller that is able to identify events recited in the logs, to include the events within a list sorted based on at least one of start times or end times indicated by the timing data, and to determine a longest duration of the events. The controller receives a requested time, calculates a prior time separated by the longest duration from the requested time, and processes the list by: identifying a first index of the list for a first event in time having a start time on or after the prior time, and identifying a last index of the list for a last event in time having a start time on or before the requested time. The controller generates a set of events bounded by the first index and the last index.

4. 发明申请

US20070075300A1 Carbon Electrode for use in aqueous electrochemical devices and method of preparation 审中-公开
标题翻译：用于水电化学装置的碳电极及其制备方法
公开(公告)号：US20070075300A1
公开(公告)日：2007-04-05
申请号：US11602614
申请日：2006-11-20
申请人： Patrick Curran , Robert Atlas
发明人： Patrick Curran , Robert Atlas
IPC分类号： H01B1/24
CPC分类号： H01G9/155 , H01M4/583 , H01M4/625 , H01M4/96 , Y02E60/13 , Y10T29/49108 , Y10T428/249921
摘要： A high tensile strength, highly conductive flexible composite sheet consisting of fibrillated PTFE polymers, performance enhancing dopants, and carbon particles useful in electrochemical devices such as flow through capacitors, capacitive deionization, electronic water purification, fuel cells, capacitors, super-capacitors and a method of preparation. The method consists of mixing the materials and calendering to the desired thickness and strength all at room temperature and leaving the material in a wet state without further drying.
摘要翻译：由原纤化PTFE聚合物，性能增强掺杂剂和用于电化学装置（例如流过电容器，电容去离子，电子水净化，燃料电池，电容器，超级电容器）和电化学装置的碳颗粒组成的高拉伸强度的高导电性柔性复合片材制备方法该方法包括将材料和压延混合到室温下所需的厚度和强度，并将材料留在湿态而不进一步干燥。

5. 发明申请

US20070072882A1 Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors 有权
标题翻译：新型吡唑并嘧啶作为细胞周期蛋白依赖性激酶抑制剂
公开(公告)号：US20070072882A1
公开(公告)日：2007-03-29
申请号：US11543182
申请日：2006-10-04
申请人： Timothy Guzi , Kamil Paruch , Michael Dwyer , M. Siddiqui , Panduranga Reddy , David Belanger , Blake Hamann , Patrick Curran
发明人： Timothy Guzi , Kamil Paruch , Michael Dwyer , M. Siddiqui , Panduranga Reddy , David Belanger , Blake Hamann , Patrick Curran
IPC分类号： A61K31/519 , C07D487/04
CPC分类号： C07D487/04
摘要： In its many embodiments, the present invention provides a class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases (CDKs), methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
摘要翻译：在其许多实施方案中，本发明提供了一类作为细胞周期蛋白依赖性激酶（CDK）抑制剂的吡唑并[1,5-a]嘧啶化合物，制备这些化合物的方法，含有一种或多种这类化合物的药物组合物，制备方法包含一种或多种这样的化合物的药物制剂，以及使用这些化合物或药物组合物治疗，预防，抑制或改善与CDK相关的一种或多种疾病的方法。

6. 发明申请

US20060111412A1 Substituted 5-oxo pyrazoles and [1,2,4]triazoles as antiviral agents 失效
标题翻译：取代的5-氧代吡唑和[1,2,4]三唑作为抗病毒剂
公开(公告)号：US20060111412A1
公开(公告)日：2006-05-25
申请号：US11259397
申请日：2005-10-26
申请人： Gerald Shipps , Tong Wang , Kristin Rosner , Patrick Curran , Alan Cooper , Viyyoor Girijavallabhan
发明人： Gerald Shipps , Tong Wang , Kristin Rosner , Patrick Curran , Alan Cooper , Viyyoor Girijavallabhan
IPC分类号： A61K31/4196 , A61K31/4152 , C07D249/12 , C07D231/08
CPC分类号： C07D231/20 , C07D231/22 , C07D401/12 , C07D403/04 , C07D409/12 , C07D417/12
摘要： The present invention provides compounds of formula I wherein X and R1-R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorders using these compounds and compositions are also provided.
摘要翻译：本发明提供式I化合物，其中X和R 1 -R 7如本文所定义。还提供了含有这些化合物的组合物，以及用于抑制HCV RNA依赖性RNA聚合酶和使用这些化合物和组合物治疗丙型肝炎和相关病症的方法。

7. 发明申请

US20070105864A1 Methods for inhibiting protein kinases 审中-公开
标题翻译：抑制蛋白激酶的方法
公开(公告)号：US20070105864A1
公开(公告)日：2007-05-10
申请号：US11598188
申请日：2006-11-08
申请人： Timothy Guzi , Kamil Paruch , Michael Dwyer , David Parry , Lianyun Zhao , Patrick Curran , David Belanger , Blake Hamann , Panduranga Reddy , M. Siddiqui , Praveen Tadikonda
发明人： Timothy Guzi , Kamil Paruch , Michael Dwyer , David Parry , Lianyun Zhao , Patrick Curran , David Belanger , Blake Hamann , Panduranga Reddy , M. Siddiqui , Praveen Tadikonda
IPC分类号： A61K31/498
CPC分类号： A61K31/4985 , A61K31/498
摘要： The present invention provides methods for inhibiting protein kinases selected from the group consisting of AKT, Checkpoint kinase, Aurora kinase, Pim-1 kinase, and tyrosine kinase using imidazo[1,2-a]pyrazine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with protein kinases using such compounds.
摘要翻译：本发明提供使用咪唑并[1,2-a]吡嗪化合物抑制选自AKT，检查点激酶，极光激酶，Pim-1激酶和酪氨酸激酶的蛋白激酶的方法以及治疗，预防，抑制，或使用这些化合物改善与蛋白激酶相关的一种或多种疾病。

8. 发明申请

US20070043045A1 Novel high affinity thiophene-based and furan-based kinase ligands 失效
标题翻译：新型高亲和力噻吩类和呋喃类激酶配体
公开(公告)号：US20070043045A1
公开(公告)日：2007-02-22
申请号：US11505263
申请日：2006-08-16
申请人： Yongqi Deng , Lianyun Zhao , Gerald Shipps , Patrick Curran , M. Siddiqui , Rumin Zhang , Charles McNemar , Todd Mayhood , William Windsor , Emma Lees , David Parry
发明人： Yongqi Deng , Lianyun Zhao , Gerald Shipps , Patrick Curran , M. Siddiqui , Rumin Zhang , Charles McNemar , Todd Mayhood , William Windsor , Emma Lees , David Parry
IPC分类号： A61K31/5377 , A61K31/497 , A61K31/496 , A61K31/4439 , A61K31/4709 , A61K31/428 , A61K31/42 , A61K31/4196 , A61K31/4178 , A61K31/4025 , A61K31/416 , C07D413/02 , C07D405/02 , C07D409/02 , C07D417/02
CPC分类号： C07D405/12 , C07D333/40 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Inhibitors of cyclin dependent kinase 2, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of making CDK-2 inhibitor compounds, methods of inhibiting CDK-2, and methods for treating disease or disease symptoms.
摘要翻译：描述了细胞周期蛋白依赖性激酶2的抑制剂，包括抑制剂的组合物，以及使用抑制剂和抑制剂组合物的方法。包括它们的抑制剂和组合物可用于治疗疾病或疾病症状。本发明还提供了制备CDK-2抑制剂化合物的方法，抑制CDK-2的方法以及治疗疾病或疾病症状的方法。

9. 发明申请

US20060111411A1 Substituted 5-carboxyamide pyrazoles and [1,2,4]triazoles as antiviral agents 失效
标题翻译：取代的5-羧酰胺吡唑和[1,2,4]三唑作为抗病毒剂
公开(公告)号：US20060111411A1
公开(公告)日：2006-05-25
申请号：US11259399
申请日：2005-10-26
申请人： Alan Cooper , Hugh Zhu , James Wang , Jagdish Desai , Gerald Shipps , Patrick Curran , D. Allen Annis , Huw Nash , Viyyoor Girijavallabhan
发明人： Alan Cooper , Hugh Zhu , James Wang , Jagdish Desai , Gerald Shipps , Patrick Curran , D. Allen Annis , Huw Nash , Viyyoor Girijavallabhan
IPC分类号： A61K31/4152 , A61K31/416 , C07D403/02
CPC分类号： C07D249/10 , C07D231/14 , C07D231/40 , C07D231/42 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/12
摘要： The present invention provides compounds of formula I wherein X, Y, R1-R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorders using these compounds and compositions are also provided.
摘要翻译：本发明提供式I化合物，其中X，Y，R 1 -R 7如本文所定义。还提供了含有这些化合物的组合物，以及用于抑制HCV RNA依赖性RNA聚合酶和使用这些化合物和组合物治疗丙型肝炎和相关病症的方法。

10. 发明申请

US20060106023A1 Novel imidazopyrazines as cyclin dependent kinase inhibitors 失效
标题翻译：新型咪唑并吡嗪作为细胞周期蛋白依赖性激酶抑制剂
公开(公告)号：US20060106023A1
公开(公告)日：2006-05-18
申请号：US11272392
申请日：2005-11-10
申请人： Timothy Guzi , Kamil Paruch , Michael Dwyer , Lianyun Zhao , Patrick Curran , David Belanger , Blake Hamann , Panduranga Reddy , M. Siddiqui
发明人： Timothy Guzi , Kamil Paruch , Michael Dwyer , Lianyun Zhao , Patrick Curran , David Belanger , Blake Hamann , Panduranga Reddy , M. Siddiqui
IPC分类号： A61K31/506 , A61K31/498 , C07D487/02
CPC分类号： C07D487/04
摘要： In its many embodiments, the present invention provides a novel class of imidazo[1,2-a]pyrazine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
摘要翻译：在其许多实施方案中，本发明提供了一类新颖的咪唑并[1,2-a]吡嗪化合物作为细胞周期蛋白依赖性激酶的抑制剂，制备此类化合物的方法，含有一种或多种此类化合物的药物组合物，制备药物制剂的方法包括一种或多种这样的化合物，以及使用这些化合物或药物组合物治疗，预防，抑制或改善与CDK相关的一种或多种疾病的方法。

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