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1. 发明授权

US08246568B2 Hemodialysis catheter with thrombus removing device 有权
标题翻译：血液透析导管与血栓去除装置
公开(公告)号：US08246568B2
公开(公告)日：2012-08-21
申请号：US12551030
申请日：2009-08-31
申请人： Michael W. Hardert , Michael R. Kurrus , Amy Lee Hruska , Tyson L. Rugenstein , Elizabeth A. Theobald
发明人： Michael W. Hardert , Michael R. Kurrus , Amy Lee Hruska , Tyson L. Rugenstein , Elizabeth A. Theobald
IPC分类号： A61M37/00 , A61M31/00
CPC分类号： A61M25/0068 , A61M25/0075 , A61M2025/0019 , A61M2025/0031 , A61M2025/0037 , A61M2025/004
摘要： The present disclosure provides apparatus and methods for removing thrombus outside of a hemodialysis. The hemodialysis catheter comprises an elongate shaft comprising a plurality of lumens. A first lumen has a first distal port. The first lumen is configured for the flow of a fluid in a first direction. A second lumen has a second distal port proximal to the first distal port. The second lumen is configured for the flow of the fluid in a second direction opposite to the first direction. A third lumen has a third distal port proximal to the second distal port. An elongate device is disposed through the third lumen. The elongate device has an operable member on a distal end or a device to connect to an operable member disposed on the elongate shaft. The operable member is configured to engage and remove thrombus from an exterior surface on the elongate shaft.
摘要翻译：本公开提供了用于去除血液透析以外的血栓的装置和方法。血液透析导管包括包括多个腔的细长轴。第一管腔具有第一远端口。第一管腔构造成用于沿第一方向流动流体。第二管腔具有靠近第一远端口的第二远端口。第二管腔构造成用于在与第一方向相反的第二方向上流动流体。第三管腔具有靠近第二远端口的第三远端端口。细长装置设置穿过第三腔。细长装置具有在远端上的可操作构件或连接到设置在细长轴上的可操作构件的装置。可操作构件构造成从细长轴上的外表面接合和去除血栓。

2. 发明申请

US20110054379A1 HEMODIALYSIS CATHETER WITH THROMBUS REMOVING DEVICE 有权
标题翻译： HEMODIALYSIS导管与THROMBUS移除装置
公开(公告)号：US20110054379A1
公开(公告)日：2011-03-03
申请号：US12551030
申请日：2009-08-31
申请人： Michael W. Hardert , Michael R. Kurrus , Amy Lee Hruska , Tyson L. Rugenstein , Elizabeth A. Theobald
发明人： Michael W. Hardert , Michael R. Kurrus , Amy Lee Hruska , Tyson L. Rugenstein , Elizabeth A. Theobald
IPC分类号： A61M1/34
CPC分类号： A61M25/0068 , A61M25/0075 , A61M2025/0019 , A61M2025/0031 , A61M2025/0037 , A61M2025/004
摘要： The present disclosure provides apparatus and methods for removing thrombus outside of a hemodialysis. The hemodialysis catheter comprises an elongate shaft comprising a plurality of lumens. A first lumen has a first distal port. The first lumen is configured for the flow of a fluid in a first direction. A second lumen has a second distal port proximal to the first distal port. The second lumen is configured for the flow of the fluid in a second direction opposite to the first direction. A third lumen has a third distal port proximal to the second distal port. An elongate device is disposed through the third lumen. The elongate device has an operable member on a distal end or a device to connect to an operable member disposed on the elongate shaft. The operable member is configured to engage and remove thrombus from an exterior surface on the elongate shaft.
摘要翻译：本公开提供了用于去除血液透析以外的血栓的装置和方法。血液透析导管包括包括多个腔的细长轴。第一管腔具有第一远端口。第一管腔构造成用于沿第一方向流动流体。第二管腔具有靠近第一远端口的第二远端口。第二管腔构造成用于在与第一方向相反的第二方向上流动流体。第三管腔具有靠近第二远端口的第三远端端口。细长装置设置穿过第三腔。细长装置具有在远端上的可操作构件或连接到设置在细长轴上的可操作构件的装置。可操作构件构造成从细长轴上的外表面接合和去除血栓。

3. 发明申请

US20090171323A1 Catheter assembly and fluid supply apparatus therefor 审中-公开
标题翻译：导管组件及其供液装置
公开(公告)号：US20090171323A1
公开(公告)日：2009-07-02
申请号：US12005177
申请日：2007-12-26
申请人： Tyson L. Rugenstein , Michael R. Kurrus , David A. Drewes, JR. , Gregory A. Frankland
发明人： Tyson L. Rugenstein , Michael R. Kurrus , David A. Drewes, JR. , Gregory A. Frankland
IPC分类号： A61M25/18
CPC分类号： A61M25/0028 , A61M39/223 , A61M2025/0037 , A61M2206/20
摘要： A catheter assembly includes a multi-lumen catheter and fluid supply apparatus for supplying fluid to said multi-lumen catheter. The fluid supply apparatus includes an inlet element for coupling to a supply of catheter fluid, a plurality of fluid outlet elements arranged to be each coupled to a respective lumen of the catheter and a flow splitter arranged between the inlet element and the outlet elements. The flow splitter is able to split or divert flow of fluid from the inlet to at least one of the plurality of outlets. For this purpose, the preferred embodiment includes a gate for directing fluid flow to one or more of the outlet elements. There may also be provided a diffuser and a nozzle.
摘要翻译：导管组件包括用于向所述多腔导管供应流体的多腔导管和流体供应装置。流体供应装置包括用于联接到导管流体供应的入口元件，多个流体出口元件，其布置成各自联接到导管的相应内腔，以及布置在入口元件和出口元件之间的分流器。分流器能够将流体从入口流到多个出口中的至少一个出口。为此，优选实施例包括用于将流体流引导到一个或多个出口元件的门。也可以设置扩散器和喷嘴。

4. 发明授权

US09987461B2 Hemodialysis catheter with thrombus blocker 有权
公开(公告)号：US09987461B2
公开(公告)日：2018-06-05
申请号：US12903677
申请日：2010-10-13
申请人： Michael W. Hardert , Michael R. Kurrus
发明人： Michael W. Hardert , Michael R. Kurrus
IPC分类号： A61M25/00 , A61M1/36
CPC分类号： A61M25/0026 , A61M1/3661
摘要： A hemodialysis catheter with a plurality of umbrella-like wire members covered with a film which works as a thrombus blocker and can easily and effectively remove the thrombus is disclosed. The hemodialysis catheter has a proximal lumen, the arterial lumen, and a distal lumen, the venous lumen. An elongate member is longitudinally put in either the proximal lumen or the distal lumen, or two elongate members in both lumens. A plurality of umbrella-like wire members are connected to the end of the elongate member. When the hemodialysis catheter is put in the vessel but not in use, the end of the lumen is capped off by the plurality of umbrella-like wire members covered with a film. When it is ready to use, the doctor can pull the elongate member which connects to the plurality of umbrella-like wire members out off the lumen inverting the plurality of umbrella-like wire members and clearing away any thrombus that has formed.

5. 发明申请

US20120095416A1 HEMODIALYSIS CATHETER WITH THROMBUS BLOCKER 有权
标题翻译： HEMODIALYSIS导管与THROMBUS阻塞器
公开(公告)号：US20120095416A1
公开(公告)日：2012-04-19
申请号：US12903677
申请日：2010-10-13
申请人： Michael W. Hardert , Michael R. Kurrus
发明人： Michael W. Hardert , Michael R. Kurrus
IPC分类号： A61M25/00
CPC分类号： A61M25/0026 , A61M1/3661
摘要： A hemodialysis catheter with a plurality of umbrella-like wire members covered with a film which works as a thrombus blocker and can easily and effectively remove the thrombus is disclosed. The hemodialysis catheter has a proximal lumen, the arterial lumen, and a distal lumen, the venous lumen. An elongate member is longitudinally put in either the proximal lumen or the distal lumen, or two elongate members in both lumens. A plurality of umbrella-like wire members are connected to the end of the elongate member. When the hemodialysis catheter is put in the vessel but not in use, the end of the lumen is capped off by the plurality of umbrella-like wire members covered with a film. When it is ready to use, the doctor can pull the elongate member which connects to the plurality of umbrella-like wire members out off the lumen inverting the plurality of umbrella-like wire members and clearing away any thrombus that has formed.
摘要翻译：公开了一种血液透析导管，其具有覆盖有膜的多个伞形线构件，其作为血栓阻断剂起作用并且可以容易且有效地去除血栓。血液透析导管具有近端内腔，动脉腔和远端腔，即静脉腔。纵向放置在近端内腔或远端腔中的细长构件或两个内腔中的两个细长构件。多个伞形线构件连接到细长构件的端部。当血液透析导管放入容器但不使用时，通过被膜覆盖的多个伞形线构件将管腔的端部封盖。当它准备使用时，医生可以将连接到多个伞形线构件的细长构件拉出反射多个伞形线构件的内腔，并清除已经形成的任何血栓。

6. 发明申请

US20140221831A1 METHOD OF INTRODUCING A CATHETER 有权
标题翻译：引入导管的方法
公开(公告)号：US20140221831A1
公开(公告)日：2014-08-07
申请号：US13761664
申请日：2013-02-07
申请人： Michael R. Kurrus , Katherine McKrill
发明人： Michael R. Kurrus , Katherine McKrill
IPC分类号： A61M25/01 , A61M5/00
CPC分类号： A61M5/007 , A61M25/0662 , A61M25/0668 , A61M29/00 , A61M2025/0681
摘要： A system and method for vessel catheterization is provided, having an introducer sheath and a catheter. The introducer sheath can include a handle and a sheath body extending from the handle. An access lumen is provided in the introducer sheath, and can include a tapered portion that is sized to receive a tapered outer surface of the catheter. The catheter may be a central venous catheter, such as a peripherally inserted central catheter, including a hub, a catheter body with at least one lumen extending distally from the hub, and at least one tube extending proximally from the hub. The introducer sheath is preferably a splittable sheath. The catheter can be inserted into the access lumen, and translated until confronting surfaces of the tapered outer surface of the catheter body and the tapered portion of the introducer sheath contact one another. This arrangement can inhibit buckling and/or kinking of the catheter during insertion, and improve initial catheter tip positioning.
摘要翻译：提供了一种用于血管导管插入术的系统和方法，其具有导引鞘和导管。引导器护套可以包括手柄和从手柄延伸的鞘体。入口腔设置在引导器护套中，并且可以包括锥形部分，其尺寸适于接纳导管的锥形外表面。导管可以是中心静脉导管，例如外围插入的中心导管，包括轮毂，具有至少一个从该毂向远侧延伸的内腔的导管主体，以及从该毂向近侧延伸的至少一个管。导引鞘优选为可分裂的鞘。导管可以插入入口腔，并且平移直到导管体的锥形外表面的相对表面和引导器护套的锥形部分彼此接触。这种布置可以在插入期间抑制导管的弯曲和/或扭结，并且改善初始的导管末端定位。

7. 发明申请

US20110152902A1 Method For Anchoring Occlusion Plug 有权
标题翻译：锚栓堵塞方法
公开(公告)号：US20110152902A1
公开(公告)日：2011-06-23
申请号：US12641021
申请日：2009-12-17
申请人： Michael R. Kurrus , Grant T. Hoffman
发明人： Michael R. Kurrus , Grant T. Hoffman
IPC分类号： A61B17/08
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12159 , A61B17/12186 , A61B17/1219 , A61B17/12195
摘要： A method for occluding a body vessel in a patient to block or reduce blood flow therethrough includes puncturing a blood vessel wall at a proximal vessel entry site with a hollow needle and extending the needle through the proximal entry site into the vessel lumen. The needle is extended through the vessel lumen and extended through the vessel wall at a distal vessel exit site into the extravascular space surrounding the distal vessel exit site. An expandable biocompatible material, such as expandable extracellular matrix (ECM) material, is then ejected though the distal end of the needle into the extravascular space. Then, while continuing to eject the expandable biocompatible plug material, the distal end of the needle is retracted back through the distal vessel exit site into the vessel lumen, such that the plug material continuously extends between the extravascular space surrounding the distal vessel exit site into the vessel lumen. When the plug material is delivered into the lumen of the vessel, the plug material expands, anchoring the plug material to the vessel wall, whereby the plug material forms an occluding plug in the vessel lumen blocking or reducing blood flow therethrough.
摘要翻译：一种用于阻塞患者体内容器以阻断或减少血液流过的方法，其中包括用中空针刺穿近端血管进入部位的血管壁并将针穿过近端进入部位延伸进入血管内腔。针穿过血管内腔延伸穿过远端血管出口部位的血管壁进入远端血管出口部位周围的血管外空间。然后将可膨胀的生物相容性材料，例如可扩张的细胞外基质（ECM）材料通过针的远端喷射到血管外空间内。然后，在继续弹出可膨胀的生物相容性塞子材料的同时，针的远端通过远端血管出口部位回缩到血管内腔中，使得栓塞材料在围绕远端血管出口部位的血管外空间之间连续延伸到血管腔。当塞子材料被输送到容器的内腔中时，塞子材料膨胀，将塞子材料锚固到血管壁上，由此栓塞材料在血管腔中形成阻塞或减少通过其中的血液流动的阻塞塞。

8. 发明申请

US20090265941A1 Shaping device 有权
标题翻译：整形装置
公开(公告)号：US20090265941A1
公开(公告)日：2009-10-29
申请号：US12386795
申请日：2009-04-23
申请人： Michael R. Kurrus
发明人： Michael R. Kurrus
IPC分类号： B26B17/00 , A61M25/14
CPC分类号： B26B17/02 , A61M25/0009 , Y10T83/8798
摘要： An elongate element, in particular a catheter, has a curved shape imparted to its end by a device comprising razor blades which are mounted on a pivotal linkage mechanism. Upon pressing actuator members against the restoring force of spring elements, the razor blades are constrained by the pivotal linkage mechanism to follow a desired curved path.
摘要翻译：细长元件，特别是导管，具有通过包括安装在枢转连杆机构上的剃刀刀片的装置向其端部施加的弯曲形状。当按压致动器构件以克服弹簧元件的恢复力时，剃刀刀片由枢转连杆机构约束以遵循所需的弯曲路径。

9. 发明授权

US09656043B2 Multi-split-tipped catheter 有权
公开(公告)号：US09656043B2
公开(公告)日：2017-05-23
申请号：US13334838
申请日：2011-12-22
申请人： Neha S. Bhagchandani , Ryan Nowicki , Michael R. Kurrus
发明人： Neha S. Bhagchandani , Ryan Nowicki , Michael R. Kurrus
IPC分类号： A61M1/00 , A61M25/00 , A61M1/36
CPC分类号： A61M25/0071 , A61M1/3661 , A61M25/0026 , A61M25/0032 , A61M25/007 , A61M2025/0031 , A61M2025/0079
摘要： A multilumen catheter with an inflow or an outflow lumen having at least two tube extensions extending from the distal end of the catheter that open into the inflow or outflow lumen. The catheter is useful in the extracorporeal treatment of blood, such as hemodialysis, hemofiltration or apheresis. A device to selectively test each of the two tube extensions for occlusion.

10. 发明授权

US08518064B2 Method for anchoring occlusion plug 有权
标题翻译：锚栓塞方法
公开(公告)号：US08518064B2
公开(公告)日：2013-08-27
申请号：US12641021
申请日：2009-12-17
申请人： Michael R. Kurrus , Grant T. Hoffman
发明人： Michael R. Kurrus , Grant T. Hoffman
IPC分类号： A61B17/08
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12159 , A61B17/12186 , A61B17/1219 , A61B17/12195
摘要： A method for occluding a body vessel in a patient to block or reduce blood flow therethrough includes puncturing a blood vessel wall at a proximal vessel entry site with a hollow needle and extending the needle through the proximal entry site into the vessel lumen. The needle is extended through the vessel lumen and extended through the vessel wall at a distal vessel exit site into the extravascular space surrounding the distal vessel exit site. An expandable biocompatible material, such as expandable extracellular matrix (ECM) material, is then ejected though the distal end of the needle into the extravascular space. Then, while continuing to eject the expandable biocompatible plug material, the distal end of the needle is retracted back through the distal vessel exit site into the vessel lumen, such that the plug material continuously extends between the extravascular space surrounding the distal vessel exit site into the vessel lumen. When the plug material is delivered into the lumen of the vessel, the plug material expands, anchoring the plug material to the vessel wall, whereby the plug material forms an occluding plug in the vessel lumen blocking or reducing blood flow therethrough.
摘要翻译：一种用于阻塞患者体内容器以阻断或减少血液流过的方法，其中包括用中空针刺穿近端血管进入部位的血管壁并将针穿过近端进入部位延伸进入血管内腔。针穿过血管内腔延伸穿过远端血管出口部位的血管壁进入远端血管出口部位周围的血管外空间。然后将可膨胀的生物相容性材料，例如可扩张的细胞外基质（ECM）材料通过针的远端喷射到血管外空间中。然后，在继续弹出可膨胀的生物相容性塞子材料的同时，针的远端通过远端血管出口部位回缩到血管内腔中，使得栓塞材料在围绕远端血管出口部位的血管外空间之间连续延伸到血管腔。当塞子材料被输送到容器的内腔中时，塞子材料膨胀，将塞子材料锚固到血管壁上，由此栓塞材料在血管腔中形成阻塞或减少通过其中的血液流动的阻塞塞。

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