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    • 1. 发明授权
    • Controlled environment device
    • US07037254B2
    • 2006-05-02
    • US10729632
    • 2003-12-05
    • Michael O'ConnorMarion E. Cox
    • Michael O'ConnorMarion E. Cox
    • A61G10/02
    • A61B90/40
    • The present invention relates to devices and methods for providing controlled environments for surgical procedures, as well as transplantation and wound healing. In particular, one embodiment of the present invention provides devices and methods to provide an anaerobic environment for incision sites. In other embodiments, the present invention provides devices and methods to maintain anaerobic conditions during the collection, transport, and implantation of organs, tissues, cells, and other transplant material. In further embodiments, the present invention provides devices and methods for the production and maintenance of an anaerobic environment surrounding sites of trauma or tissue injury. In particular, the present invention provides devices and methods which allow the operator to strictly control the environment for surgical procedures, transplantation and wound healing, etc. Thus, the present invention also finds use in specialized settings where hyperoxic conditions are desireable.
    • 2. 发明授权
    • Controlled environment device
    • 受控环境设备
    • US06685622B2
    • 2004-02-03
    • US09972236
    • 2001-10-05
    • Michael O'ConnorMarion E. Cox
    • Michael O'ConnorMarion E. Cox
    • A61G1002
    • A61B90/40
    • The present invention relates to devices and methods for providing controlled environments for surgical procedures, as well as transplantation and wound healing. In particular, one embodiment of the present invention provides devices and methods to provide an anaerobic environment for incision sites. In other embodiments, the present invention provides devices and methods to maintain anaerobic conditions during the collection, transport, and implantation of organs, tissues, cells, and other transplant material. In further embodiments, the present invention provides devices and methods for the production and maintenance of an anaerobic environment surrounding sites of trauma or tissue injury. In particular, the present invention provides devices and methods which allow the operator to strictly control the environment for surgical procedures, transplantation and wound healing, etc. Thus, the present invention also finds use in specialized settings where hyperoxic conditions are desireable.
    • 本发明涉及用于提供用于外科手术的受控环境以及移植和伤口愈合的装置和方法。 特别地,本发明的一个实施例提供了为切割部位提供厌氧环境的装置和方法。 在其它实施方案中,本发明提供在器官,组织,细胞和其他移植材料的收集,运输和植入期间维持厌氧条件的装置和方法。 在另外的实施方案中,本发明提供用于生产和维持围绕创伤或组织损伤部位的厌氧环境的装置和方法。 特别地,本发明提供了允许操作者严格控制外科手术,移植和伤口愈合等环境的装置和方法。因此,本发明还可用于需要高氧条件的专门设置。
    • 5. 发明授权
    • Preparation of contaminant free containers of culture medium
    • 制备无污染物的培养基容器
    • US4262091A
    • 1981-04-14
    • US34493
    • 1979-04-27
    • Marion E. Cox
    • Marion E. Cox
    • B01L1/04C12M1/00C12M1/04C12N1/20
    • C12M29/26B01L1/04Y10S435/80Y10S435/801Y10S435/81
    • A method and apparatus are described for providing petri dishes of a culture medium in an oxygen-free manner. Empty petri dishes are supplied to a dispensing glove box chamber providing isolation from the ambient atmosphere, by communicably connecting to such dispensing chamber, another glove box chamber providing isolation from the ambient atmosphere containing the empty dishes. The dishes are sequentially transferred to the dispensing chamber where they are filled with autoclaved culture medium. The filled dishes are transferred to a third chamber (also communicably connected to the dispensing chamber) within which the culture medium can solidify. Once the third chamber is filled with dishes having culture medium it is disconnected from the dispensing chamber and replaced with a fourth chamber having a new batch of unfilled petri dishes. The dishes from the new batch are then transferred into the dispensing glove box chamber and, once filled, transferred into the now empty chamber which provided the original batch of unfilled dishes. Each chamber containing filled petri dishes maintains such dishes in an isolated environment for a selected incubation period, and the dishes therein are then individually packaged in hermetically tight packages prior to being exposed to the ambient atmosphere.
    • 描述了以无氧方式提供培养基的培养皿的方法和装置。 将空的培养皿供应到分配手套箱​​室,通过可通信地连接到这种分配室,提供与环境大气的隔离,另一个手套箱室提供与包含空的餐具的环境空气的隔离。 将菜肴顺序地转移到分配室中,在那里它们被高压灭菌的培养基填充。 填充的菜肴被转移到培养基可以固化的第三室(也可连通地连接到分配室)。 一旦第三个房间充满了培养基的盘子,它就与分配室断开连接,并且更换为具有新批次的未填充培养皿的第四室。 来自新批次的菜肴然后被转移到分配手套箱​​室中,并且一旦填充,就被转移到现在的空的室中,这提供了原始的一批未填充的菜肴。 每个含有填充培养皿的培养皿在隔离的环境中保持这样的菜肴用于所选择的潜伏期,然后将其中的菜肴在暴露于环境气氛之前单独包装在密封的包装中。