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1. 发明授权

US5529084A Laminar flow elbow system and method 失效
标题翻译：层流弯头系统及方法
公开(公告)号：US5529084A
公开(公告)日：1996-06-25
申请号：US217362
申请日：1994-03-24
申请人： Michael Mutsakis , Chang-Li Hsieh , Dag O. Calafell, II
发明人： Michael Mutsakis , Chang-Li Hsieh , Dag O. Calafell, II
IPC分类号： F15D1/04 , F17D1/20
CPC分类号： F15D1/04 , Y10T137/0391
摘要： An improved laminar flow elbow system and method wherein the elbow system comprises a straight pre-pipe section to define the flow path of a fluid; the pipe section included directly prior to the inlet of a curved pipe section and having and comprising a plurality of vanes to impart a rotation to the fluid before passing through a curved pipe section to provide a generally flat velocity profile at the exit of the curved pipe section and to minimize turbulence of the fluid as it passes through the curved pipe section, and a substantially straight post-pipe section to define a flow path exit pipe section included directly at the exit of the curved pipe section, and containing a plurality of vanes to impart a backward rotation movement to the fluid flow from the exit of the curved pipe section, to substantially terminate rotation of the fluid upon exiting from the straight pipe section without substantial deterioration of the flatness of the fluid velocity profile and without generating substantial amounts of turbulence.
摘要翻译：改进的层流弯头系统和方法，其中所述弯头系统包括用于限定流体的流动路径的直的预管段; 管段直接包括在弯管部分的入口之前，并且具有并包括多个叶片，以在通过弯管部分之前向流体施加旋转，从而在弯管的出口处提供大致平坦的速度分布并且使流体在通过弯曲管部时的紊流最小化，以及基本上直的后管部，以限定直接包括在弯曲管部的出口处的流路出口管部，并且容纳多个叶片以向来自弯曲管部分的出口的流体流动提供反向旋转运动，以在从直管部分离开时基本上终止流体的旋转，而不会使流体速度分布的平坦度基本上劣化，并且不产生大量的湍流

2. 发明授权

US4919541A Gas-liquid mass transfer apparatus and method 失效
标题翻译：气液传质装置及方法
公开(公告)号：US4919541A
公开(公告)日：1990-04-24
申请号：US849002
申请日：1986-04-07
申请人： Friedrick Grosz-Roell , Michael Mutsakis , Robert G. Rader
发明人： Friedrick Grosz-Roell , Michael Mutsakis , Robert G. Rader
IPC分类号： F28C3/08 , B01J19/32 , F28C3/06
CPC分类号： F28C3/06 , B01J19/32 , B01J2219/3221 , B01J2219/32213 , F28D2021/0052
摘要： A gas-liquid mass transfer apparatus and method, such as for the rapid heating of a liquid stream by a heated gas stream, such as steam, or the rapid dissolving of a gas stream into a liquid stream, which apparatus comprises: a housing having an axial flow path; static or motionless mixing elements disposed in the axial flow path; and passages in the housing to provide for the direct introduction of the gas stream into and about the liquid stream in the axial flow path and substantially along the length of the static mixing elements to provide a mixed product stream.
摘要翻译：一种气液传质装置和方法，例如用于通过加热的气流（例如蒸汽）快速加热液体流，或将气流快速溶解到液体流中，该装置包括：壳体，其具有轴向流路; 设置在轴向流路中的静止或静止混合元件; 以及壳体中的通道以提供气流在轴向流动路径中并且基本上沿着静态混合元件的长度直接引入液体流中并围绕液体流引导，以提供混合产物流。

3. 发明授权

US5565361A Bioreactor for culturing and propagating cells with a woven motionless mixing element 失效
标题翻译：生物反应器，用于织造无静止混合元件培养和繁殖细胞
公开(公告)号：US5565361A
公开(公告)日：1996-10-15
申请号：US455843
申请日：1995-05-31
申请人： Michael Mutsakis , Joseph P. Porcelli
发明人： Michael Mutsakis , Joseph P. Porcelli
IPC分类号： C12M3/04 , C12M1/02 , C12M1/14
CPC分类号： C12M27/18 , C12M25/02
摘要： A bioreactor, motionless mixing element with attached cells, and method for the enhanced cultivation and propagation of cells in a bioreactor method, and which bioreactor comprises a housing and contains within the housing a motionless mixing element, the attachment of cells to the mixing element and a nutrient composition permitting the cell growth and division of the attached cells, and which motionless mixing element and the method and bioreactor comprise a porous, fibrous sheet material; for example, of a corrugated or knitted, woven wire material, such as stainless steel or titanium, and of selected dimensions as to the fiber diameter and height, to provide a maximum surface area for the attachment of the cells to be cultivated, with the ratio of the fibrous, geometric surface area of the porous, fibrous sheet material to that of a sheet material of the same shape being greater than about 1.0; for example, 1.5, and typically, for example, having a surface area for cell growth of about 2000 to 3000 M.sup.2 /M.sup.3.
摘要翻译：具有附着细胞的生物反应器，不动混合元件和用于在生物反应器方法中增强细胞培养和繁殖的方法，并且该生物反应器包括壳体并且在壳体内包含静态混合元件，将细胞附着到混合元件和允许细胞生长和分离附着的细胞的营养组合物，以及不动的混合元件和所述方法和生物反应器包含多孔的纤维片材; 例如波纹或编织的编织线材，例如不锈钢或钛，并且对于纤维直径和高度具有选定尺寸，以提供用于附着待培养的细胞的最大表面积，与多孔纤维片材的纤维状几何表面积与相同形状的片状材料的纤维状几何表面积之比大于约1.0; 例如，1.5，通常例如具有约2000至3000M2 / M3的细胞生长的表面积。

4. 发明授权

US5476783A Bioreactor method of culturing and propagating cells with a woven motionless mixing element 失效
标题翻译：用编织不动混合元件培养和繁殖细胞的生物反应器方法
公开(公告)号：US5476783A
公开(公告)日：1995-12-19
申请号：US114462
申请日：1993-08-31
申请人： Michael Mutsakis , Joseph P. Porcelli
发明人： Michael Mutsakis , Joseph P. Porcelli
IPC分类号： C12M3/04 , C12N5/00 , C12M1/02 , C12M1/14
CPC分类号： C12M27/18 , C12M25/02
摘要： A bioreactor, motionless mixing element with attached cells, and method for the enhanced cultivation and propagation of cells in a bioreactor method, and which bioreactor comprises a housing and contains within the housing a motionless mixing element, the attachment of cells to the mixing element and a nutrient composition permitting the cell growth and division of the attached cells, and which motionless mixing element and the method and bioreactor comprise a porous, fibrous sheet material; for example, of a corrugated or knitted, woven wire material, such as stainless steel or titanium, and of selected dimensions as to the fiber diameter and height, to provide a maximum surface area for the attachment of the cells to be cultivated, with the ratio of the fibrous, geometric surface area of the porous, fibrous sheet material to that of a sheet material of the same shape being greater than about 1.0; for example, 1.5, and typically, for example, having a surface area for cell growth of about 2000 to 3000 M.sup.2 /M.sup.3.
摘要翻译：具有附着细胞的生物反应器，不动混合元件和用于在生物反应器方法中增强细胞培养和繁殖的方法，并且该生物反应器包括壳体并且在壳体内包含静态混合元件，将细胞附着到混合元件和允许细胞生长和分离附着的细胞的营养组合物，以及不动的混合元件和所述方法和生物反应器包含多孔的纤维片材; 例如波纹或编织的编织线材，例如不锈钢或钛，并且对于纤维直径和高度具有选定尺寸，以提供用于附着待培养的细胞的最大表面积，与多孔纤维片材的纤维状几何表面积与相同形状的片状材料的纤维状几何表面积之比大于约1.0; 例如，1.5，通常例如具有约2000至3000M2 / M3的细胞生长的表面积。

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