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1. 发明申请

US20090202603A1 Compacted 2,2-dibromo-3-nitrilopropionamide 有权
标题翻译：压实的2,2-二溴-3-硝基丙酰胺
公开(公告)号：US20090202603A1
公开(公告)日：2009-08-13
申请号：US12381904
申请日：2009-03-17
申请人： Michael Lupin , Ayala Lupin , David Feldman
发明人： Michael Lupin , Ayala Lupin , David Feldman
IPC分类号： A01N25/34 , A01N37/34 , A01P1/00
CPC分类号： C07C255/19 , A01N37/34 , A01N25/34 , A01N25/12 , A01N2300/00
摘要： The present invention provides an essentially pure compacted 2,2-Dibromo-3-nitrilopropionamide (DBNPA) in a granular and/or tablet and/or briquette and/or pellet form. The present invention further provides a process for preparing the same essentially pure compacted DBNPA.
摘要翻译：本发明提供了颗粒状和/或片状和/或块状和/或颗粒形式的基本上纯的压制的2,2-二溴-3-硝基丙酰胺（DBNPA）。本发明还提供了制备相同的基本上纯的压实的DBNPA的方法。

2. 发明授权

US08114905B2 Compacted 2,2-dibromo-3-nitrilopropionamide 有权
标题翻译：压实的2,2-二溴-3-硝基丙酰胺
公开(公告)号：US08114905B2
公开(公告)日：2012-02-14
申请号：US12381904
申请日：2009-03-17
申请人： Michael Lupin , Ayala Lupin, legal representative , David Feldman
发明人： Michael Lupin , David Feldman
IPC分类号： A01N37/34 , A01N43/30
CPC分类号： C07C255/19 , A01N37/34 , A01N25/34 , A01N25/12 , A01N2300/00
摘要： The present invention provides an essentially pure compacted 2,2-Dibromo-3-nitrilopropionamide (DBNPA) in a granular and/or tablet and/or briquette and/or pellet form. The present invention further provides a process for preparing the same essentially pure compacted DBNPA.
摘要翻译：本发明提供了颗粒状和/或片状和/或块状和/或颗粒形式的基本上纯的压制的2,2-二溴-3-硝基丙酰胺（DBNPA）。本发明还提供了制备相同的基本上纯的压实的DBNPA的方法。

3. 发明授权

US08628788B2 Formulations containing a non-oxidative biocide and a source of active halogen and use thereof in water treatment 有权
标题翻译：含有非氧化性杀生物剂和活性卤素源的制剂及其在水处理中的应用
公开(公告)号：US08628788B2
公开(公告)日：2014-01-14
申请号：US11922952
申请日：2007-02-25
申请人： David Feldman , Michel Adda , Raymond J. Roccon
发明人： David Feldman , Michel Adda , Raymond J. Roccon
IPC分类号： A01N37/18 , A01N59/02 , A01N59/00 , A01P1/00 , A61K31/275 , A61K33/14 , A61K33/20 , A61K33/40
CPC分类号： C02F1/766 , A01N35/08 , A01N37/34 , A01N59/00 , C02F1/50 , C02F1/72 , C02F1/722 , C02F1/76 , C02F2103/34 , C02F2303/04 , C02F2305/02 , A01N25/04 , A01N25/16 , A01N25/30 , A01N2300/00
摘要： Novel formulations containing a non-oxidative biocide, such as DBNPA, and a source of an in situ produced active biocide, such as a concentrated aqueous solution of an inorganic halide salt, are disclosed. These novel formulations are particularly effective in the treatment of water, and are characterized by high stability, desirable rheological properties and an excellent biocidal activity.
摘要翻译：公开了含有非氧化性杀生物剂（例如DBNPA）的新型制剂和原位产生的活性杀生物剂的来源，例如无机卤化物盐的浓缩水溶液。这些新型制剂在水的处理中特别有效，其特征在于高稳定性，所需的流变性质和优异的杀生物活性。

4. 发明申请

US20130303608A1 STABLE AQUEOUS SUSPENSIONS OF DBNPA, THEIR PREPARATION AND USES THEREOF AS BIOCIDES 审中-公开
标题翻译：稳定的DBNPA悬浮液，其制备及其作为生物体的用途
公开(公告)号：US20130303608A1
公开(公告)日：2013-11-14
申请号：US13884726
申请日：2011-11-15
申请人： Evgeny Shapiro , David Feldman , Rimma Khodakovskaya
发明人： Evgeny Shapiro , David Feldman , Rimma Khodakovskaya
IPC分类号： A01N37/34 , A01N25/04
CPC分类号： A01N37/34 , A01N25/04 , A01N2300/00
摘要： The present invention discloses novel biocide composition comprising 2,2-dibromo-3-nitrilopropionamide (DBNPA) being in the form of a stable aqueous suspension. Further are disclosed the preparation of these compositions and their biocidal uses.
摘要翻译：本发明公开了包含2,2-二溴-3-次氮基丙酰胺（DBNPA）的稳定水性悬浮液形式的新型杀生物剂组合物。还公开了这些组合物及其杀生物剂用途的制备。

5. 发明授权

US08114298B2 Method, device and system for water treatment 有权
标题翻译：水处理方法，装置和系统
公开(公告)号：US08114298B2
公开(公告)日：2012-02-14
申请号：US12309947
申请日：2007-08-02
申请人： Theodore Fishler , David Feldman , Dietmar Werner
发明人： Theodore Fishler , David Feldman , Dietmar Werner
IPC分类号： C02F1/76
CPC分类号： C02F1/76 , B01F1/0022 , B01F1/0038 , B01F5/0057 , B01F5/0415 , B01F5/0498 , B01F5/102 , B01F13/1027 , B01F15/00207 , B01F15/00253 , B01F15/0235 , C02F1/008 , C02F1/687 , C02F1/766 , C02F2201/008 , C02F2209/001 , C02F2209/003 , C02F2209/005 , C02F2209/008 , C02F2209/40 , C02F2209/42 , C02F2301/043
摘要： A device, system and method are provided for treating water, in which a water treating agent is prepared and dispensed to an untreated drinking water source in discrete and consecutive control volumes enabling untreated water in the untreated water source to be treated thereby to provide potable water.
摘要翻译：提供了一种用于处理水的装置，系统和方法，其中制备水处理剂并以不连续的和连续的控制体积将其分配到未处理的饮用水源中，从而能够处理未处理的水源中的未经处理的水，从而提供饮用水。

6. 发明申请

US20060051284A1 Process for the preparation of concentrated solutions of stabilized hypobromites 审中-公开
标题翻译：制备稳定的次溴酸盐浓缩溶液的方法
公开(公告)号：US20060051284A1
公开(公告)日：2006-03-09
申请号：US10513512
申请日：2003-05-05
申请人： Theodor Fishler , David Feldman
发明人： Theodor Fishler , David Feldman
IPC分类号： C01B11/20
CPC分类号： C02F1/766 , C01B11/20
摘要： The invention is a process for the preparation of stabilized aqueous solutions of alkali hypobromites, which comprises reacting a concentrated alkali hydroxide aqueous solution with bromine, allowing the mixture to react, adding to the reaction product, which is a non-stabilized solution, an aqueous solution of a sulfamic compound, such as sodium sulfamate, and thus forming stabilized alkali hypobromite solution. This solution can be further stabilized by the addition of a sulfamate solution. The temperatures of all the above stages are comprised between −5 and +10° C.
摘要翻译：本发明是制备稳定的碱性次溴酸盐水溶液的方法，其包括使浓缩的碱金属氢氧化物水溶液与溴反应，使混合物反应，加入作为非稳定溶液的反应产物，水溶液氨基磺酸盐等氨基磺酸盐化合物的溶液，形成稳定的碱性次溴酸盐溶液。可以通过加入氨基磺酸盐溶液来进一步稳定该溶液。所有上述阶段的温度都在-5和+ 10℃之间

7. 发明申请

US20050182042A1 Pharmaceutical composition comprising a renin inhibitor, a calcium channel blocker and a diuretic 审中-公开
标题翻译：药物组合物，其包含肾素抑制剂，钙通道阻断剂和利尿剂
公开(公告)号：US20050182042A1
公开(公告)日：2005-08-18
申请号：US10514683
申请日：2003-05-16
申请人： David Feldman , Randy Webb
发明人： David Feldman , Randy Webb
IPC分类号： A61K31/137 , A61K31/165 , A61K31/192 , A61K31/196 , A61K31/277 , A61K31/341 , A61K31/385 , A61K31/4184 , A61K31/4409 , A61K31/4422 , A61K31/4439 , A61K31/4545 , A61K31/455 , A61K31/495 , A61K31/4965 , A61K31/517 , A61K31/519 , A61K31/549 , A61K31/554 , A61K31/585 , A61K45/06 , A61P3/10 , A61P9/00 , A61P9/04 , A61P9/06 , A61P9/10 , A61P9/12 , A61P13/12 , A61P15/00 , A61P17/00 , A61P21/00 , A61P25/06 , A61P25/28 , A61P27/06 , A61P35/00
CPC分类号： A61K45/06
摘要： The invention relates to a pharmaceutical composition comprising (i) a renin inhibitor, (ii) a calcium channel blocker (CCB), and (iii) a diuretic and to a method of treatment of a condition or a disease selected from the group consisting of hypertension, heart failure such as (acute and chronic) congestive heart failure, left ventricular dysfunction and hypertrophic cardiomyopathy, diabetic cardiac myopathy, supraventricular and ventricular arrhythmias, atrial fibrillation, atrial flutter, detrimental vascular remodeling, myocardial infarction and its sequelae, atherosclerosis, angina (whether unstable or stable), renal insufficiency (diabetic and non-diabetic), heart failure, angina pectoris, diabetes, secondary aldosteronism, primary and secondary pulmonary hypertension, renal failure conditions, such as diabetic nephropathy, glomerulonephritis (including IgA nephropathy), renal fibrosis, scleroderma, glomerular sclerosis, proteinuria of renal disease, and also renal vascular hypertension, diabetic retinopathy, the management of other vascular disorders, such as migraine, peripheral vascular disease, Raynaud's disease, luminal hyperplasia, cognitive dysfunction (such as Alzheimer's), glaucoma and stroke, pulmonary and hepatic fibrosis, fibrotic diseases resulting from accumulation of excess extracellular matrix induced by TGF, and proliferative diseases of smooth muscle cells, including uterine fibroids comprising administering a therapeutically effective amount of said pharmaceutical composition to a mammal in need of such treatment.
摘要翻译：本发明涉及一种药物组合物，其包含（i）肾素抑制剂，（ii）钙通道阻滞剂（CCB），和（iii）利尿剂和治疗选自以下的疾病或疾病的方法：高血压，心力衰竭（急性和慢性）充血性心力衰竭，左心室功能障碍和肥大性心肌病，糖尿病性心肌病，室上性心室性心律失常，心房颤动，心房扑动，有害血管重塑，心肌梗塞及其后遗症，动脉粥样硬化，心绞痛（不稳定或稳定），肾功能不全（糖尿病和非糖尿病），心力衰竭，心绞痛，糖尿病，继发性醛固酮增多症，原发性和继发性肺动脉高压，肾衰竭病症如糖尿病性肾病，肾小球肾炎（包括IgA肾病）肾纤维化，硬皮病，肾小球硬化，肾脏疾病的蛋白尿，以及肾血管性高血压糖尿病视网膜病变，其他血管疾病如偏头痛，外周血管疾病，雷诺氏病，管腔增生，认知功能障碍（如阿尔茨海默氏症），青光眼和中风，肺和肝纤维化的管理，由过量积累引起的纤维化疾病由TGF诱导的细胞外基质和平滑肌细胞的增殖性疾病，包括子宫肌瘤，包括向需要这种治疗的哺乳动物施用治疗有效量的所述药物组合物。

8. 发明授权

US5234678A Method and apparatus for chlorine dioxide manufacture 失效
标题翻译：制造二氧化氯的方法和装置
公开(公告)号：US5234678A
公开(公告)日：1993-08-10
申请号：US875883
申请日：1992-04-29
申请人： Aaron Rosenblatt , David H. Rosenblatt , David Feldman , Joseph E. Knapp , Diane Battisti , Badie Morsi
发明人： Aaron Rosenblatt , David H. Rosenblatt , David Feldman , Joseph E. Knapp , Diane Battisti , Badie Morsi
IPC分类号： C01B11/02
CPC分类号： C01B11/024
摘要： A method and apparatus for the generation, use, and disposal of chlorine dioxide is disclosed. A solid sodium chlorite composition having impurities, at least one of which is sodium hydroxide, is contacted with an agent to consume essentially all of the sodium hydroxide. Chlorine dioxide gas is then generated by contacting the resultant composition with chlorine in a humidified inert carrier gas. The resultant chlorine dioxide gas mixture may then be treated to remove chlorine gas present therein by contacting the same with soda-lime in particulate form. After using the chlorine dioxide gas mixture in the desired manner, chlorine dioxide present in the spent effluent gas may be substantially removed via the introduction of the effluent gas into an aqueous solution of sodium thiosulfate having a sufficient amount of an inorganic base to maintain the alkalinity of the solution during consumption of thiosulfate by chlorine dioxide.
摘要翻译：公开了用于产生，使用和处理二氧化氯的方法和装置。具有至少一种氢氧化钠的杂质的固体亚氯酸钠组合物与试剂接触以消耗基本上所有的氢氧化钠。然后通过使所得组合物与加湿的惰性载气中的氯接触来产生二氧化氯气体。然后可以将所得二氧化氯气体混合物与颗粒形式的钠钙接触，从而除去其中存在的氯气。以所需方式使用二氧化氯气体混合物后，废弃废气中存在的二氧化氯可以通过将流出气体引入具有足够量的无机碱的硫代硫酸钠水溶液中而基本上除去，以保持碱度在二氧化氯消耗硫代硫酸盐时的溶液。

9. 发明申请

US20210016154A1 RING FOR A FIGHTING SPORT 有权
公开(公告)号：US20210016154A1
公开(公告)日：2021-01-21
申请号：US16980632
申请日：2019-03-14
申请人： David Feldman
发明人： David Feldman
IPC分类号： A63C19/00 , A63B71/00 , A63C19/08 , A63C19/06
摘要： A ring for a fighting sport has a circular fighting area defined by a plurality of circular fence rings that are held up by posts. Shock absorbers connect the fence rings to the posts. Position markers are provided to indicate the starting positions of the participating fighters at certain points during the bout.

10. 发明申请

US20120121728A1 STABILIZED AND ACTIVATED BROMINE SOLUTIONS AS A BIOCIDE AND AS AN ANTIFOULING AGENT 有权
标题翻译：稳定和活化的溴解决方案作为生物活性剂和抗菌剂
公开(公告)号：US20120121728A1
公开(公告)日：2012-05-17
申请号：US13322469
申请日：2010-06-07
申请人： Shlomo Antebi , Chen Zolkov , David Feldman
发明人： Shlomo Antebi , Chen Zolkov , David Feldman
IPC分类号： A01N59/00 , A01N43/66 , A01P1/00 , A01N43/50
CPC分类号： A01N47/28 , A01N59/00 , A01N25/02 , A01N43/50 , A01N43/64 , A01N2300/00
摘要： The invention provides a process of removing or preventing biofouling, particularly on surfaces of industrial and agricultural equipment in contact with aqueous liquids. The process employs an antifouling composition of stabilized active halogen having a low pH.
摘要翻译：本发明提供了除去或防止生物污垢的方法，特别是在与含水液体接触的工业和农业设备的表面上。该方法采用具有低pH的稳定的活性卤素的防污组合物。

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