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    • 5. 发明申请
    • HIGH-RESOLUTION MASS SPECTROMETER AND METHODS FOR DETERMINING THE ISOTOPIC ANATOMY OF ORGANIC AND VOLATILE MOLECULES
    • 用于确定有机和挥发性分子的同位素解析度的高分辨率质谱仪和方法
    • US20130103337A1
    • 2013-04-25
    • US13656447
    • 2012-10-19
    • John M. Eiler
    • John M. Eiler
    • H01J49/26G06F19/00G01V5/00
    • G06F19/703
    • A mass spectrometer including an entrance slit, an energy filter, a momentum filter and a detector array, the entrance slit, energy filter and momentum filter being configured to provide molecular analyte ions to the detector array at a mass resolution of about 20,000 or greater. A method for determining the isotopic composition of an analyte in a sample includes converting the analyte to molecular analyte ions, separating the molecular analyte ions using an entrance slit, separating the molecular analyte ions according to their energy levels, separating the molecular analyte ions according to their momenta, detecting two or more of the molecular analyte ions at a mass resolution of about 20,000 or greater to produce molecular analyte ion data; and analyzing the molecular analyte data to determine the isotopic composition of at least a portion of the analyte.
    • 包括入口狭缝,能量过滤器,动量滤波器和检测器阵列的质谱仪,入口狭缝,能量过滤器和动量过滤器被配置为以大约20,000或更大的质量分辨率向分析器阵列提供分子分析物离子。 用于确定样品中分析物的同位素组成的方法包括将分析物转化为分子分析物离子,使用入口狭缝分离分子分析物离子,根据分子分析物离子的能级分离分子分析物离子,根据 他们的瞬间,以大约20,000或更大的质量分辨率检测两个或更多个分子分析物离子,以产生分子分析物离子数据; 并分析分子分析物数据以确定分析物的至少一部分的同位素组成。