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1. 发明授权

US09249231B2 Motif-specific and context-independent antibodies that specifically bind to a cleaved caspase motif 有权
标题翻译：与特异性结合切割的半胱天冬酶基序的母体特异性和上下文相关抗体
公开(公告)号：US09249231B2
公开(公告)日：2016-02-02
申请号：US13289651
申请日：2011-11-04
申请人： Michael Comb , Ailan Guo , John Edward Rush, II , Jun-Ming Cai , Jing Li , Jing Zhou
发明人： Michael Comb , Ailan Guo , John Edward Rush, II , Jun-Ming Cai , Jing Li , Jing Zhou
IPC分类号： C07K16/44 , C07K16/00 , C12N5/07
CPC分类号： C07K16/18 , C07K16/44 , C07K2317/14 , C07K2317/20 , C07K2317/33 , C07K2317/34
摘要： There is provided a motif-specific, context-independent antibody that specifically binds a recurring, modified motif consisting of (i) at least one sumoylated lysine residue, and (ii) one or more degenerate amino acids bound by a peptide bond to said sumoylated lysine residue, said antibody specifically binding said motif in a plurality of non-homologous peptides or proteins within an organism in which it recurs. Also provided is a motif-specific, context-independent antibody that specifically binds a recurring, modified motif consisting of (i) a C-terminal aspartic acid residue, and (ii) one or more degenerate amino acids bound by a peptide bond to said C-terminal aspartic acid residue, said antibody specifically binding said motif in a plurality of non-homologous peptides or proteins within an organism in which it recurs.
摘要翻译：提供了一种特异性基因，独立于上下文的抗体，其特异性结合由（i）至少一个sumoylated赖氨酸残基组成的复发性修饰基序，和（ii）通过肽键与所述sumoylated结合的一个或多个简并氨基酸赖氨酸残基，所述抗体特异性结合所述基序在其再次发生的生物体内的多个非同源肽或蛋白质中。还提供了一种特异性基因，独立于上下文的抗体，其特异性结合由（i）C末端天冬氨酸残基组成的重复修饰基序，和（ii）一个或多个与肽键结合的简并氨基酸与所述 C末端天冬氨酸残基，所述抗体特异性结合所述基序在其再次发生的生物体内的多个非同源肽或蛋白质中。

2. 发明申请

US20120208985A1 Motif-Specific and Context-Independent Antibodies That Specifically Bind to a Cleaved Caspase Motif or a Sumoylated Lysine-Containing Motif 有权
标题翻译：特异性和上下文独立的抗体，其特异性结合到切割的半胱天冬酶母体或含有Sumoylated赖氨酸的基序
公开(公告)号：US20120208985A1
公开(公告)日：2012-08-16
申请号：US13289651
申请日：2011-11-04
申请人： Michael Comb , Ailan Guo , John Edward Rush, II , Jun-Ming Cai , Jing Li , Jing Zhou
发明人： Michael Comb , Ailan Guo , John Edward Rush, II , Jun-Ming Cai , Jing Li , Jing Zhou
IPC分类号： C07K16/00
CPC分类号： C07K16/18 , C07K16/44 , C07K2317/14 , C07K2317/20 , C07K2317/33 , C07K2317/34
摘要： There is provided a motif-specific, context-independent antibody that specifically binds a recurring, modified motif consisting of (i) at least one sumoylated lysine residue, and (ii) one or more degenerate amino acids bound by a peptide bond to said sumoylated lysine residue, said antibody specifically binding said motif in a plurality of non-homologous peptides or proteins within an organism in which it recurs. Also provided is a motif-specific, context-independent antibody that specifically binds a recurring, modified motif consisting of (i) a C-terminal aspartic acid residue, and (ii) one or more degenerate amino acids bound by a peptide bond to said C-terminal aspartic acid residue, said antibody specifically binding said motif in a plurality of non-homologous peptides or proteins within an organism in which it recurs.
摘要翻译：提供了一种特异性基因，独立于上下文的抗体，其特异性结合由（i）至少一个sumoylated赖氨酸残基组成的复发性修饰基序，和（ii）通过肽键与所述sumoylated结合的一个或多个简并氨基酸赖氨酸残基，所述抗体特异性结合所述基序在其再次发生的生物体内的多个非同源肽或蛋白质中。还提供了一种特异性基因，独立于上下文的抗体，其特异性结合由（i）C末端天冬氨酸残基组成的重复修饰基序，和（ii）一个或多个与肽键结合的简并氨基酸与所述 C末端天冬氨酸残基，所述抗体特异性结合所述基序在复制的生物体内的多个非同源肽或蛋白质。

3. 发明申请

US20110111424A1 ANALYSIS OF UBIQUITINATED POLYPEPTIDES 审中-公开
标题翻译：不饱和聚酯的分析
公开(公告)号：US20110111424A1
公开(公告)日：2011-05-12
申请号：US12967284
申请日：2010-12-14
申请人： John Edward Rush, II , Jing Li , Ailan Guo
发明人： John Edward Rush, II , Jing Li , Ailan Guo
IPC分类号： G01N33/53 , C07K16/00
CPC分类号： C07K16/00 , G01N33/6842 , G01N2440/36
摘要： The invention relates to antibody reagents that specifically bind to peptides carrying a ubiquitin remnant from a digested or chemically treated biological sample. The reagents allow the technician to identify ubiquitinated polypeptides as well as the sites of ubiquitination on them. The reagents are preferably employed in proteomic analysis using mass spectrometry. The antibody reagents specifically bind to the remnant of ubiquitin (i.e., a diglycine modified epsilon amine of lysine) left on a peptide which as been generated by digesting or chemically treating ubiquitinated proteins. The inventive antibody reagents' affinity to the ubiquitin remnant does not depend on the remaining amino acid sequences flanking the modified (i.e., ubiquitinated) lysine, i.e., they are context independent.
摘要翻译：本发明涉及与经消化或经化学处理的生物样品中携带泛素残基的肽特异性结合的抗体试剂。试剂允许技术人员识别泛素化的多肽以及它们上泛素化的位点。试剂优选用于使用质谱的蛋白质组学分析。抗体试剂特异性结合残留在通过消化或化学处理泛素化蛋白质产生的肽上的泛素（即，赖氨酸的二甘氨酸修饰的ε胺）残基。本发明的抗体试剂对泛素残留物的亲和力不依赖于修饰（即泛素化）赖氨酸侧翼的剩余氨基酸序列，即它们是上下文无关的。

4. 外观设计

USD998213S1 Bowl star projector 有权
公开(公告)号：USD998213S1
公开(公告)日：2023-09-05
申请号：US29780473
申请日：2021-04-25
申请人： Jing Li
设计人： Jing Li
摘要： FIG. 1 is a perspective view of a bowl star projector showing my new design;
FIG. 2 is a front elevation view thereof;
FIG. 3 is a rear elevation view thereof;
FIG. 4 is a left side elevation view thereof;
FIG. 5 is a right side elevation view thereof;
FIG. 6 is a top plan view thereof; and,
FIG. 7 is a bottom plan view thereof.
The broken lines depict portions of the bowl star projector that form no part of the claimed design.

5. 外观设计

USD982943S1 Storage cabinet 有权
公开(公告)号：USD982943S1
公开(公告)日：2023-04-11
申请号：US29881765
申请日：2023-01-06
申请人： Jing Li
设计人： Jing Li

6. 外观设计

USD982220S1 Projector lamp 有权
公开(公告)号：USD982220S1
公开(公告)日：2023-03-28
申请号：US29775298
申请日：2021-03-23
申请人： Jing Li
设计人： Jing Li

7. 发明申请

US20200263380A1 TUBULAR RIVET FOUNDATION FOR ONSHORE WIND TURBINE GENERATORS 审中-公开
公开(公告)号：US20200263380A1
公开(公告)日：2020-08-20
申请号：US16278037
申请日：2019-02-15
申请人： Dongyuan Wang , Jing Li , Ying Han
发明人： Dongyuan Wang , Jing Li , Ying Han
IPC分类号： E02D27/42 , F03D13/20 , E02D15/04
摘要： Embodiments of the present foundation for wind turbine generators comprise four structural members: a relatively long central hollow pier, several arm grade beams, a continued grade beam and a continued shear key. The central hollow pier positions in the center of the foundation system, arm grade beams are arranged evenly in radial direction and extend from the pier to the continued grade beam. Continued grade beam is arranged circumferentially in outer periphery and the continued shear key is built below it. Arm grade beams have a varied section with the far end embedding into ground. The top of the continued grade beam matches the top of arm grade beams, while the continued shear key embeds deeper into ground. All structural members are constructed of cast-in-place concrete reinforced with rebars, and all connections are fixed and rigid. The present foundation uses the ground to shape and form the structural members, no formwork, backfilling and compaction is needed.

8. 发明授权

US09580968B2 Rotary steerable drilling tool with electromagnetic steering system 有权
标题翻译：带电磁转向系统的旋转导向钻具
公开(公告)号：US09580968B2
公开(公告)日：2017-02-28
申请号：US14308458
申请日：2014-06-18
申请人： Ce Liu , Treston Davis , Ricki Marshall , Jing Li
发明人： Ce Liu , Treston Davis , Ricki Marshall , Jing Li
IPC分类号： E21B7/24 , E21B7/06
CPC分类号： E21B7/24 , E21B7/067
摘要： A rotary steerable drilling tool with an electromagnetic steering system can include a drill collar, a bit shaft, an orientation control module, a mud tube, a mud tube coupler, a universal joint, a mud sealing device, and a drill bit. The bit shaft can be mechanically coupled to the drill collar through the universal joint and the orientation control module and rotate about the universal joint. The orientation and the inclination angle of the bit shaft against the drill collar can be controlled by the orientation control module with the electromagnetic steering system. The orientation control module can include an array of electromagnets, an array of permanent magnets, a rotor, and a set of bearings. The orientation control module can be coupled to the bit shaft through the rotor. The movement of the rotor can be driven by the interaction between the array of electromagnets and the array of permanent magnets.
摘要翻译：具有电磁转向系统的旋转可转向钻具可以包括钻铤，钻头轴，定向控制模块，泥浆管，泥浆管联接器，万向接头，泥浆密封装置和钻头。钻头轴可以通过万向接头和定向控制模块机械联接到钻铤，并围绕万向接头旋转。钻头轴相对于钻铤的方向和倾斜角度可以由具有电磁转向系统的定向控制模块来控制。定向控制模块可以包括电磁体阵列，永磁体阵列，转子和一组轴承。定向控制模块可以通过转子耦合到钻头轴。转子的运动可以通过电磁体阵列与永磁体阵列之间的相互作用来驱动。

9. 发明授权

US09537112B2 Solid-state compositions and methods for generating white light 有权
标题翻译：固态组合物和产生白光的方法
公开(公告)号：US09537112B2
公开(公告)日：2017-01-03
申请号：US14239616
申请日：2012-08-19
申请人： Jing Li , Mojgan Roushan
发明人： Jing Li , Mojgan Roushan
IPC分类号： C09K11/08 , C09K11/56 , C09K11/57 , C09K11/88 , H01L51/50 , H01L33/50
CPC分类号： H01L51/5036 , C09K11/883 , H01L33/502 , Y02B20/181
摘要： This application discloses a new family of inorganic-organic hybrid semiconductor bulk materials built on periodic nanostructured 2D layers of ZnS that emit bright white light with high quantum efficiency. These ZnS-based crystalline inorganic-organic hybrid semiconductors have well defined and precisely controllable crystal structure and composition. Their optical emission properties, including intensity, quantum yield, and color quality, can be systematically tuned by varying the composition of both inorganic and organic components. Methods for preparing these materials, use of these materials as a new type of single-phased white light emitting phosphors, and their applications in making WLED devices are also disclosed.
摘要翻译：该申请公开了一种新型的无机 - 有机杂化半导体体材料系列，它们建立在发射具有高量子效率的亮白光的ZnS的周期性纳米结构2D层上。这些基于ZnS的结晶无机 - 有机杂化半导体具有良好的定义和精确控制的晶体结构和组成。可以通过改变无机组分和有机组分的组成来系统地调节它们的光学发射性质，包括强度，量子产率和颜色质量。还公开了制备这些材料的方法，使用这些材料作为新型的单相白色发光荧光体，以及它们在制备WLED器件中的应用。

10. 发明授权

US09499565B2 Cocrystal of piperacillin sodium and sulbactam sodium and preparation method thereof, as well as pharmaceutical compositions containing same and uses thereof 有权
标题翻译：哌拉西林钠和舒巴坦钠的晶体及其制备方法，以及含有其的药物组合物及其用途
公开(公告)号：US09499565B2
公开(公告)日：2016-11-22
申请号：US14428239
申请日：2012-09-14
申请人： Haiyong Wang , Jing Li
发明人： Haiyong Wang , Jing Li
IPC分类号： A61K31/43 , A61K31/496 , C07D499/887 , C07D499/00 , C07D499/04 , C07D499/68
CPC分类号： C07D499/887 , A61K31/43 , A61K31/496 , C07D499/00 , C07D499/04 , C07D499/68
摘要： Provided in the present invention are a cocrystal of piperacillin sodium and sulbactam sodium and preparation method thereof, as well as pharmaceutical compositions containing the same and uses thereof in treating infections caused by drug-resistant bacteria, such as a “super bacterium” producing NDM-1 and the like. The cocrystal of piperacillin sodium and sulbactam sodium contains diffraction angles of 14.24°, 16.58°, 16.79°, 17.77°, 19.20°, 20.21°, 20.39°, 23.06°, 27.86° and 32.16° represented by 2θ in an X-ray powder diffraction analysis spectrum.
摘要翻译：本发明提供了哌拉西林钠和舒巴坦钠的共结晶体及其制备方法，以及含有该组合物的药物组合物及其用于治疗由耐药性细菌引起的感染，如产生NDM-1的“超细菌” 1等。哌拉西林钠和舒巴坦钠共结晶含有X射线粉末中由2θ表示的衍射角为14.24°，16.58°，16.79°，17.77°，19.20°，20.21°，20.39°，23.06°，27.86°和32.16° 衍射分析光谱。

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