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1. 发明申请

US20090195852A1 Producing Filters With Combined Transmission and/or Reflection Functions 有权
标题翻译：生产具有组合传输和/或反射功能的滤波器
公开(公告)号：US20090195852A1
公开(公告)日：2009-08-06
申请号：US12025394
申请日：2008-02-04
申请人： Michael Bassler , Peter Kiesel , Markus Beck , Alex Hegyi , Tobias Buergel , Noble M. Johnson
发明人： Michael Bassler , Peter Kiesel , Markus Beck , Alex Hegyi , Tobias Buergel , Noble M. Johnson
IPC分类号： G02F1/01
CPC分类号： G01N21/645 , G01N21/0303 , G01N21/05 , G01N21/53 , G01N21/6486 , G01N2021/0346 , G01N2021/6421 , G01N2021/6471
摘要： A transmissive and/or reflective optical filter can receive input light, which can emanate from objects traveling along paths past the filter, e.g. from biological cells, viruses, colored spots or other markings on documents, and so forth. In response, the filter can provide output light in accordance with a combined transmission function that is approximately equal to a superposition or scaled superposition of a set of simpler transmission functions. The set can include two or more non-uniform transmission functions, a subset of which can be different from each other and positioned relative to each other so that the output light has time variation in accordance with each of the functions in the subset. The subset could include, for example, a random function and a periodic function, a chirp function and a periodic function, or any other suitable combination of two or more simpler functions.
摘要翻译：透射和/或反射光学滤光器可以接收输入光，其可以从沿着过滤器的路径行进的物体发射，例如，来自生物细胞，病毒，彩色斑点或文件上的其他标记等等。作为响应，滤波器可以根据组合传输函数提供输出光，其大致等于一组更简单的传输函数的叠加或缩放叠加。该集合可以包括两个或多个非均匀传输函数，其子集可以彼此不同并且相对于彼此定位，使得输出光具有根据子集中的每个功能的时间变化。子集可以包括例如随机函数和周期函数，啁啾函数和周期函数，或两个或更多个更简单函数的任何其它合适的组合。

2. 发明申请

US20090195773A1 Transmitting/Reflecting Emanating Light With Time Variation 有权
标题翻译：发射/反射发光随时间变化
公开(公告)号：US20090195773A1
公开(公告)日：2009-08-06
申请号：US12024490
申请日：2008-02-01
申请人： Michael Bassler , Markus Beck , Peter Kiesel , Alex Hegyi , Tobias Buergel , Noble M. Johnson
发明人： Michael Bassler , Markus Beck , Peter Kiesel , Alex Hegyi , Tobias Buergel , Noble M. Johnson
IPC分类号： G02B5/22 , G01N21/00
CPC分类号： G01N21/05 , G01N21/255 , G01N21/645 , G01N2021/0346
摘要： A filter arrangement can transmit and/or reflect light emanating from a moving object so that the emanating light has time variation, and the time variation can include information about the object, such as its type. For example, emanating light from segments of a path can be transmitted/reflected through positions of a filter assembly, and the transmission functions of the positions can be sufficiently different that time variation occurs in the emanating light between segments. Or emanating light from a segment can be transmitted/reflected through a filter component in which simpler transmission functions are superimposed, so that time variation occurs in the emanating light in accordance with superposition of two simpler non-uniform transmission functions. Many filter arrangements could be used, e.g. the filter component could include the filter assembly, which can have one of the simpler non-uniform transmission functions. Time-varying waveforms from sensing results can be compared to obtain spectral differences.
摘要翻译：滤波器装置可以发射和/或反射从移动物体发出的光，使得发射光具有时间变化，并且时间变化可以包括关于物体的信息，例如其类型。例如，可以通过路径的区段发出光，并通过过滤器组件的位置进行透射/反射，并且位置的透射函数可以充分地不同，从而在区间之间的发光中发生时间变化。或者发射来自光束的光可以通过其中叠加更简单的透射函数的滤光器部件被透射/反射，使得根据两个更简单的不均匀透射函数的叠加在发射光中发生时间变化。可以使用许多过滤装置，例如过滤器组件可以包括过滤器组件，其可以具有更简单的不均匀传输功能之一。可以比较感测结果中的时变波形，以获得光谱差异。

3. 发明授权

US07701580B2 Transmitting/reflecting emanating light with time variation 有权
标题翻译：发射/反射发光随时间变化
公开(公告)号：US07701580B2
公开(公告)日：2010-04-20
申请号：US12024490
申请日：2008-02-01
申请人： Michael Bassler , Markus Beck , Peter Kiesel , Alex Hegyi , Tobias Buergel , Noble M. Johnson
发明人： Michael Bassler , Markus Beck , Peter Kiesel , Alex Hegyi , Tobias Buergel , Noble M. Johnson
IPC分类号： G01N21/25
CPC分类号： G01N21/05 , G01N21/255 , G01N21/645 , G01N2021/0346
摘要： A filter arrangement can transmit and/or reflect light emanating from a moving object so that the emanating light has time variation, and the time variation can include information about the object, such as its type. For example, emanating light from segments of a path can be transmitted/reflected through positions of a filter assembly, and the transmission functions of the positions can be sufficiently different that time variation occurs in the emanating light between segments. Or emanating light from a segment can be transmitted/reflected through a filter component in which simpler transmission functions are superimposed, so that time variation occurs in the emanating light in accordance with superposition of two simpler non-uniform transmission functions. Many filter arrangements could be used, e.g. the filter component could include the filter assembly, which can have one of the simpler non-uniform transmission functions. Time-varying waveforms from sensing results can be compared to obtain spectral differences.
摘要翻译：滤波器装置可以发射和/或反射从移动物体发出的光，使得发射光具有时间变化，并且时间变化可以包括关于物体的信息，例如其类型。例如，可以通过路径的区段发出光，并通过过滤器组件的位置进行透射/反射，并且位置的透射函数可以充分地不同，从而在区间之间的发光中发生时间变化。或者发射来自光束的光可以通过其中叠加更简单的透射函数的滤光器部件被透射/反射，使得根据两个更简单的不均匀透射函数的叠加在发射光中发生时间变化。可以使用许多过滤装置，例如过滤器组件可以包括过滤器组件，其可以具有更简单的不均匀传输功能之一。可以比较感测结果中的时变波形，以获得光谱差异。

4. 发明授权

US07894068B2 Producing filters with combined transmission and/or reflection functions 有权
标题翻译：生成具有组合传输和/或反射功能的滤波器
公开(公告)号：US07894068B2
公开(公告)日：2011-02-22
申请号：US12025394
申请日：2008-02-04
申请人： Michael Bassler , Peter Kiesel , Markus Beck , Alex Hegyi , Tobias Buergel , Noble M. Johnson
发明人： Michael Bassler , Peter Kiesel , Markus Beck , Alex Hegyi , Tobias Buergel , Noble M. Johnson
IPC分类号： G01N21/25 , G01N21/00 , G01N21/55
CPC分类号： G01N21/645 , G01N21/0303 , G01N21/05 , G01N21/53 , G01N21/6486 , G01N2021/0346 , G01N2021/6421 , G01N2021/6471
摘要： A transmissive and/or reflective optical filter can receive input light, which can emanate from objects traveling along paths past the filter, e.g. from biological cells, viruses, colored spots or other markings on documents, and so forth. In response, the filter can provide output light in accordance with a combined transmission function that is approximately equal to a superposition or scaled superposition of a set of simpler transmission functions. The set can include two or more non-uniform transmission functions, a subset of which can be different from each other and positioned relative to each other so that the output light has time variation in accordance with each of the functions in the subset. The subset could include, for example, a random function and a periodic function, a chirp function and a periodic function, or any other suitable combination of two or more simpler functions.
摘要翻译：透射和/或反射光学滤光器可以接收输入光，其可以从沿着过滤器的路径行进的物体发射，例如，来自生物细胞，病毒，彩色斑点或文件上的其他标记等等。作为响应，滤波器可以根据组合传输函数提供输出光，其大致等于一组更简单的传输函数的叠加或缩放叠加。该集合可以包括两个或多个非均匀传输函数，其子集可以彼此不同并且相对于彼此定位，使得输出光具有根据子集中的每个功能的时间变化。子集可以包括例如随机函数和周期函数，啁啾函数和周期函数，或两个或更多个更简单函数的任何其它合适的组合。

5. 发明申请

US20090190121A1 Obtaining Information From Time Variation of Sensing Results 有权
标题翻译：从感知结果的时间变化获取信息
公开(公告)号：US20090190121A1
公开(公告)日：2009-07-30
申请号：US12022485
申请日：2008-01-30
申请人： Alex Hegyi , Michael Bassler , Peter Kiesel , Noble M. Johnson
发明人： Alex Hegyi , Michael Bassler , Peter Kiesel , Noble M. Johnson
IPC分类号： G01N21/00 , G01B11/00 , G01P3/36 , G01J3/46 , G01N33/48
CPC分类号： G01N21/05 , B01L3/5027 , B01L3/502761 , G01N15/12 , G01N15/1429 , G01N15/1434 , G01N15/1463 , G01N15/1475 , G01N15/1484 , G01N2015/1037 , G01N2015/1075 , G01N2015/1093 , G01N2015/1254 , G01N2015/1472 , G01N2015/1486 , G01N2021/0346
摘要： Sensing results from moving objects, e.g. from photosensing emanating light or from impedance-based sensing, can indicate sensed time-varying waveforms with information about objects. For example, a sensed time-varying waveform can be compared with another waveform, such as a reference waveform produced by objects of a certain type, to obtain comparison results indicating motion-independent information about the object; time-scaling can adjust for displacement rate such as speed. Also, a modulation periodicity value can be obtained from a sensed time-varying waveform and used in obtaining information about an object; for example, a periodic modulation frequency can be used with a given time's chirp frequency to obtain phase information about an object's position. Or, where periodic modulation frequency indicates displacement rate, time scaling during comparison can use a scaling factor based on the frequency. Objects can move fluidically as in flow cytometry or through scanning movement, as in document scanning.
摘要翻译：感测来自移动物体的结果，例如从光敏发射光或基于阻抗的感测可以用关于对象的信息来指示感测的时变波形。例如，可以将感测到的时变波形与诸如由某种类型的对象产生的参考波形的另一波形进行比较，以获得指示关于对象的运动无关信息的比较结果; 时间缩放可以调整速度等位移速率。此外，可以从感测到的时变波形获得调制周期值，并用于获得关于对象的信息; 例如，可以使用周期调制频率与给定时间的啁啾频率来获得关于对象的位置的相位信息。或者，在周期性调制频率表示位移速率的情况下，比较期间的时间缩放可以使用基于频率的缩放因子。物体可以像流式细胞仪一样流动，也可以通过扫描运动进行流动，如文档扫描。

6. 发明授权

US07817254B2 Obtaining information from time variation of sensing results 有权
标题翻译：从感测结果的时间变化中获取信息
公开(公告)号：US07817254B2
公开(公告)日：2010-10-19
申请号：US12022485
申请日：2008-01-30
申请人： Alex Hegyi , Michael Bassler , Peter Kiesel , Noble M. Johnson
发明人： Alex Hegyi , Michael Bassler , Peter Kiesel , Noble M. Johnson
IPC分类号： G01P3/36
CPC分类号： G01N21/05 , B01L3/5027 , B01L3/502761 , G01N15/12 , G01N15/1429 , G01N15/1434 , G01N15/1463 , G01N15/1475 , G01N15/1484 , G01N2015/1037 , G01N2015/1075 , G01N2015/1093 , G01N2015/1254 , G01N2015/1472 , G01N2015/1486 , G01N2021/0346
摘要： Sensing results from moving objects, e.g. from photosensing emanating light or from impedance-based sensing, can indicate sensed time-varying waveforms with information about objects. For example, a sensed time-varying waveform can be compared with another waveform, such as a reference waveform produced by objects of a certain type, to obtain comparison results indicating motion-independent information about the object; time-scaling can adjust for displacement rate such as speed. Also, a modulation periodicity value can be obtained from a sensed time-varying waveform and used in obtaining information about an object; for example, a periodic modulation frequency can be used with a given time's chirp frequency to obtain phase information about an object's position. Or, where periodic modulation frequency indicates displacement rate, time scaling during comparison can use a scaling factor based on the frequency. Objects can move fluidically as in flow cytometry or through scanning movement, as in document scanning.
摘要翻译：感测来自移动物体的结果，例如从光敏发射光或基于阻抗的感测可以用关于对象的信息来指示感测的时变波形。例如，可以将感测到的时变波形与诸如由某种类型的对象产生的参考波形的另一波形进行比较，以获得指示关于对象的运动无关信息的比较结果; 时间缩放可以调整速度等位移速率。此外，可以从感测到的时变波形获得调制周期值，并用于获得关于对象的信息; 例如，可以使用周期调制频率与给定时间的啁啾频率来获得关于对象的位置的相位信息。或者，在周期性调制频率表示位移速率的情况下，比较期间的时间缩放可以使用基于频率的缩放因子。物体可以像流式细胞仪一样流动，也可以通过扫描运动进行流动，如文档扫描。

7. 发明授权

US08263955B2 Causing relative motion 有权
标题翻译：造成相对运动
公开(公告)号：US08263955B2
公开(公告)日：2012-09-11
申请号：US12337796
申请日：2008-12-18
申请人： Peter Kiesel , Markus Beck , Michael Bassler , Noble M. Johnson
发明人： Peter Kiesel , Markus Beck , Michael Bassler , Noble M. Johnson
IPC分类号： G01N21/55 , G01N21/25 , G01N21/00
CPC分类号： G01N15/1429 , G01N15/1459 , G01N21/532 , G01N21/645 , G01N21/65 , G01N2015/1075
摘要： Sensors can be used to obtain encoded sensing results from objects that have nonuniform relative motion. A photosensor or impedance-based sensor, for example, can obtain sensing results from objects that have relative motion within a sensing region relative to the sensor, with the relative motion being, for example, periodically varying, randomly varying, chirp-varying, or modulated relative motion that completes at least one modulation cycle within the sensing region. Relative motion can be caused by varying objects' speed and/or direction or by controlling flow of fluid carrying objects, movement of a channel, movement of a support structure, movement of a sensor, and/or pattern movement. A fluidic implementation can include shaped channel wall parts and/or a displacement component causing time-varying lateral displacement. A support structure implementation can include a scanner device and a rotary device that respectively control scanning and rotating movement of a movable support structure or of a sensor.
摘要翻译：传感器可用于从具有不均匀相对运动的物体获得编码的感测结果。例如，光传感器或基于阻抗的传感器可以从相对于传感器的感测区域内具有相对运动的物体获得感测结果，相对运动例如是周期性变化的，随机变化的线性调频脉冲变化或调制的相对运动，其在感测区域内完成至少一个调制周期。可以通过改变物体的速度和/或方向或通过控制流体携带物体的流动，通道的移动，支撑结构的运动，传感器的运动和/或图案运动来引起相对运动。流体实现可以包括形成通道壁部分和/或引起时变横向位移的位移部件。支撑结构实现可以包括分别控制可移动支撑结构或传感器的扫描和旋转运动的扫描器装置和旋转装置。

8. 发明授权

US08153950B2 Obtaining sensing results and/or data in response to object detection 有权
标题翻译：获取响应于物体检测的感测结果和/或数据
公开(公告)号：US08153950B2
公开(公告)日：2012-04-10
申请号：US12337771
申请日：2008-12-18
申请人： Peter Kiesel , Markus Beck , Joerg Martini , Michael Bassler , Noble M. Johnson
发明人： Peter Kiesel , Markus Beck , Joerg Martini , Michael Bassler , Noble M. Johnson
IPC分类号： G01J1/42 , F21V9/16 , G01N21/25
CPC分类号： G01J3/2803 , G01J3/02 , G01J3/027 , G01N15/12 , G01N15/1429 , G01N15/1459 , G01N2015/1075 , G01N2021/1734
摘要： An encoder/sensor can obtain sensing results from objects in an encoding/sensing region; a trigger detector can respond to objects in a trigger detection region, providing respective trigger signals; and a relative motion component can cause relative motion of objects into the trigger detection region, from it into the encoding/sensing region, and within the encoding/sensing region. In response to an object's trigger signal, control circuitry can cause the encoder/sensor and/or the relative motion component to operate so that the encoder/sensor obtains sensing results indicating a time-varying waveform and processing circuitry can obtain data from the sensing results indicating a time-varying waveform. The time-varying waveform can include information resulting from the relative motion within the encoding/sensing region. The encoder/sensor and trigger detector can be implemented, for example, with discrete components or as sets of cells in a photosensing array on an integrated circuit.
摘要翻译：编码器/传感器可以从编码/感测区域中的对象获得感测结果; 触发检测器可以响应触发检测区域中的对象，提供相应的触发信号; 并且相对运动分量可以引起物体进入触发检测区域的相对运动，从而进入编码/感测区域，并且在编码/感测区域内。响应于物体的触发信号，控制电路可以使编码器/传感器和/或相对运动分量运行，使得编码器/传感器获得指示时变波形的感测结果，并且处理电路可以从感测结果获得数据表示时变波形。时变波形可以包括由编码/感测区域内的相对运动产生的信息。编码器/传感器和触发检测器可以例如利用集成电路中的光敏阵列中的分立组件或单元组来实现。

9. 发明申请

US20100157291A1 Causing Relative Motion 有权
标题翻译：导致相对运动
公开(公告)号：US20100157291A1
公开(公告)日：2010-06-24
申请号：US12337796
申请日：2008-12-18
申请人： Peter Kiesel , Markus Beck , Michael Bassler , Noble M. Johnson
发明人： Peter Kiesel , Markus Beck , Michael Bassler , Noble M. Johnson
IPC分类号： G01N21/01
CPC分类号： G01N15/1429 , G01N15/1459 , G01N21/532 , G01N21/645 , G01N21/65 , G01N2015/1075
摘要： Sensors can be used to obtain encoded sensing results from objects that have nonuniform relative motion. A photosensor or impedance-based sensor, for example, can obtain sensing results from objects that have relative motion within a sensing region relative to the sensor, with the relative motion being, for example, periodically varying, randomly varying, chirp-varying, or modulated relative motion that completes at least one modulation cycle within the sensing region. Relative motion can be caused by varying objects' speed and/or direction or by controlling flow of fluid carrying objects, movement of a channel, movement of a support structure, movement of a sensor, and/or pattern movement. A fluidic implementation can include shaped channel wall parts and/or a displacement component causing time-varying lateral displacement. A support structure implementation can include a scanner device and a rotary device that respectively control scanning and rotating movement of a movable support structure or of a sensor.
摘要翻译：传感器可用于从具有不均匀相对运动的物体获得编码的感测结果。例如，光传感器或基于阻抗的传感器可以从相对于传感器的感测区域内具有相对运动的物体获得感测结果，相对运动例如是周期性变化的，随机变化的线性调频脉冲变化或调制的相对运动，其在感测区域内完成至少一个调制周期。可以通过改变物体的速度和/或方向或通过控制流体携带物体的流动，通道的移动，支撑结构的运动，传感器的运动和/或图案运动来引起相对运动。流体实现可以包括形成通道壁部分和/或引起时变横向位移的位移部件。支撑结构实现可以包括分别控制可移动支撑结构或传感器的扫描和旋转运动的扫描器装置和旋转装置。

10. 发明授权

US08153949B2 Obtaining sensing results indicating time variation 有权
标题翻译：获取指示时间变化的感测结果
公开(公告)号：US08153949B2
公开(公告)日：2012-04-10
申请号：US12337737
申请日：2008-12-18
申请人： Peter Kiesel , Joerg Martini , Michael Bassler , Markus Beck , Noble M. Johnson
发明人： Peter Kiesel , Joerg Martini , Michael Bassler , Markus Beck , Noble M. Johnson
IPC分类号： G01J1/42 , F21V9/16 , G01N21/25
CPC分类号： G01N15/1429 , G01N15/1056 , G01N15/12 , G01N15/1459 , G01N2015/1006 , G01N2015/1037 , G01N2015/1075
摘要： In response to objects having relative motion within an encoding/sensing region relative to an encoder/sensor that, e.g., photosenses emanating light or performs impedance-based sensing, sensing results can indicate sensed time-varying waveforms with information about the objects, about their relative motion, about excitation characteristics, about environmental characteristics, and so forth. An encoder/sensor can include, for example, a non-periodic arrangement of sensing elements; a longitudinal sequence of sensing elements with a combined sensing pattern that approximates a superposition or scaled superposition of simpler sensing patterns; and/or IC-implemented sensing elements that include photosensing arrays on ICs and readout/combine circuitry that reads out photosensed quantities from cells in groups in accordance with cell-group sensing patterns and combines the readout photosensed quantities to obtain the sensing results. Objects can move fluidically as in flow cytometry, through scanning movement as in document scanning, or in other ways.
摘要翻译：响应于相对于编码器/传感器在编码/感测区域内具有相对运动的物体，例如，发出光的光照或执行基于阻抗的感测，感测结果可以指示感测到的具有关于物体的信息的时变波形，关于它们相对运动，关于激发特性，关于环境特性等。编码器/传感器可以包括例如感测元件的非周期性布置; 具有组合感测图案的感测元件的纵向序列，其近似于更简单的感测图案的叠加或缩放叠加; 和/或IC实现的感测元件，其包括IC上的光敏阵列和读出/组合电路，其根据单元组感测图案从组中的单元读出光照量，并组合读出的光照量以获得感测结果。物体可以像流式细胞仪一样流动地进行扫描运动，如文档扫描或其他方式。

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