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1. 发明申请

US20110251592A1 DEVICES FOR MAINTAINING SURGICALLY CREATED OPENINGS 审中-公开
标题翻译：用于维护创伤性开口的装置
公开(公告)号：US20110251592A1
公开(公告)日：2011-10-13
申请号：US12939961
申请日：2010-11-04
申请人： Michael BIGGS , Thomas KEAST , Bryan LOOMAS , Don TANAKA , David THOMPSON , Gary KAPLAN , Kelly SHRINER , Halil KARABEY , Russ REDMOND , Claude VIDAL , Mike COLLINSON , Cary COLE , Michael WILLINK
发明人： Michael BIGGS , Thomas KEAST , Bryan LOOMAS , Don TANAKA , David THOMPSON , Gary KAPLAN , Kelly SHRINER , Halil KARABEY , Russ REDMOND , Claude VIDAL , Mike COLLINSON , Cary COLE , Michael WILLINK
IPC分类号： A61M25/00 , A61B18/18
CPC分类号： A61F2/86 , A61B17/0218 , A61B17/064 , A61B17/068 , A61B17/12022 , A61B17/12104 , A61B17/12172 , A61B2017/00252 , A61B2017/0046 , A61B2017/00477 , A61F2/07 , A61F2/2412 , A61F2/91 , A61F2002/043 , A61F2220/0008 , A61F2220/0016 , A61F2230/005 , A61F2230/0054 , A61F2230/0078
摘要： Devices and methods are directed to improving the gaseous exchange in a lung of an individual having, for instance, chronic obstructive pulmonary disease. More particularly, conduits may be deployed in the lung to maintain collateral openings (or channels) surgically created through airway walls. This tends to facilitate both the exchange of oxygen ultimately into the blood and decompress hyper-inflated lungs. The conduit includes a radially expandable center section having a first end, a second end, and a passageway extending from the first end to the second end. A control segment may be associated with the conduit to limit the degree of radial expansion. The conduit further includes a plurality of deflectable members extending from the ends of the center section. A tissue barrier may coaxially surround the conduit such that tissue ingrowth is prevented. The conduits may also include hold-down members and bioactive coatings that serve to prevent ejection of the conduit as well as prevent narrowing of the passageway due to tissue ingrowth.
摘要翻译：装置和方法旨在改善具有例如慢性阻塞性肺疾病的个体的肺中的气体交换。更具体地，导管可以部署在肺中以保持通过气道壁手术产生的侧支开口（或通道）。这倾向于促进氧气最终进入血液并减压超膨胀的肺。导管包括具有第一端，第二端和从第一端延伸到第二端的通道的可径向扩张的中心部分。控制段可以与管道相关联以限制径向膨胀的程度。导管还包括从中心部分的端部延伸的多个可偏转构件。组织屏障可以同轴地围绕导管，从而防止组织向内生长。导管还可以包括用于防止导管喷射的压紧构件和生物活性涂层，并且防止由于组织向内生长导致的通道变窄。

2. 发明申请

US20130218158A1 METHODS OF REDUCING MUCUS IN AIRWAYS 审中-公开
标题翻译：降低空中航班的方法
公开(公告)号：US20130218158A1
公开(公告)日：2013-08-22
申请号：US13853588
申请日：2013-03-29
申请人： Christopher James DANEK , Michael BIGGS , Bryan LOOMAS , Michael D. LAUFER , Gary KAPLAN , Kelly SHRINER
发明人： Christopher James DANEK , Michael BIGGS , Bryan LOOMAS , Michael D. LAUFER , Gary KAPLAN , Kelly SHRINER
IPC分类号： A61B18/12
CPC分类号： A61B18/12 , A61B17/22004 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/1485 , A61B18/1492 , A61B2017/00115 , A61B2017/00292 , A61B2017/003 , A61B2017/22062 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/044 , A61B2018/046 , A61B2018/1807 , A61B2090/3614 , A61M25/0043 , A61M29/00 , A61M2025/0096 , A61M2210/1039 , A61N5/0601
摘要： This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.
摘要翻译：这涉及治疗哮喘肺，更具体地涉及将治疗装置推进到肺中并用装置治疗肺。这还包括治疗气道壁，向哮喘肺中的气道壁施加能量或热量的附加步骤。

3. 发明申请

US20130211402A1 METHODS OF TREATING INFLAMMATION IN AIRWAYS 有权
标题翻译：在空气中处理炎症的方法
公开(公告)号：US20130211402A1
公开(公告)日：2013-08-15
申请号：US13852067
申请日：2013-03-28
申请人： Christopher J. DANEK , Michael BIGGS , Bryan E. LOOMAS , Michael D. LAUFER , Gary KAPLAN , Kelly M. SHRINER
发明人： Christopher J. DANEK , Michael BIGGS , Bryan E. LOOMAS , Michael D. LAUFER , Gary KAPLAN , Kelly M. SHRINER
IPC分类号： A61B18/14
CPC分类号： A61B18/12 , A61B17/22004 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/1485 , A61B18/1492 , A61B2017/00115 , A61B2017/00292 , A61B2017/003 , A61B2017/22062 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/044 , A61B2018/046 , A61B2018/1807 , A61B2090/3614 , A61M25/0043 , A61M29/00 , A61M2025/0096 , A61M2210/1039 , A61N5/0601
摘要： This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.
摘要翻译：这涉及治疗哮喘肺，更具体地涉及将治疗装置推进到肺中并用装置治疗肺。这还包括治疗气道壁，向哮喘肺中的气道壁施加能量或热量的附加步骤。

4. 发明申请

US20060247727A1 CONTROL SYSTEM AND PROCESS FOR APPLICATION OF ENERGY TO AIRWAY WALLS AND OTHER MEDIUMS 有权
标题翻译：能源对航空公司和其他媒体应用的控制系统和过程
公开(公告)号：US20060247727A1
公开(公告)日：2006-11-02
申请号：US11458084
申请日：2006-07-17
申请人： Michael BIGGS , Roger STERN , Christopher DANEK
发明人： Michael BIGGS , Roger STERN , Christopher DANEK
IPC分类号： A61N1/00
CPC分类号： A61N1/06 , A61B18/14 , A61B2018/00541 , A61N1/40
摘要： The present invention includes a system for delivering energy to an airway wall of a lung comprising an energy delivering apparatus and a PID controller having one or more variable gain factors which are rest after energy deliver has begun. The energy delivering apparatus may include a flexible elongated member and a distal expandable basket having at least one electrode for transferring energy to the airway wall and at least one temperature sensor for measuring temperature. The PID controller determines a new power set point base on an error between a preset temperature and the measured temperature. The algorithm can be Pi+1=Pi+G(αei+βei−1+γei−2) where α, β and γ are preset values and α is from 1 to 2; β is from −1 to −2; and γ is from −0.5 to 0-5. In another variation, the controller is configured to shut down if various measured parameters are exceeded such as, for example, energy, impedance, temperature, temperature differences, activation time and combinations thereof. Methods for treating a target medium using a PID algorithm are also provided.
摘要翻译：本发明包括一种用于向肺气道壁输送能量的系统，包括能量输送装置和具有一个或多个可变增益因子的PID控制器，所述可变增益因子在能量传递开始之后休息。能量输送装置可以包括柔性细长构件和远端可膨胀篮，其具有用于将能量传递到气道壁的至少一个电极和用于测量温度的至少一个温度传感器。 PID控制器根据预设温度和测量温度之间的误差确定新的功率设定点。该算法可以是P + 1 + 1 + 1 + 1 + 1 + 其中α，β和γ是预设值，α是1至2; β为-1至-2; 而γ为-0.5至0-5。在另一变型中，控制器被配置为如果超过各种测量参数，例如能量，阻抗，温度，温差，激活时间及其组合，则关闭。还提供了使用PID算法处理目标介质的方法。

5. 发明申请

US20060247726A1 CONTROL SYSTEM AND PROCESS FOR APPLICATION OF ENERGY TO AIRWAY WALLS AND OTHER MEDIUMS 有权
标题翻译：能源对航空公司和其他媒体应用的控制系统和过程
公开(公告)号：US20060247726A1
公开(公告)日：2006-11-02
申请号：US11458074
申请日：2006-07-17
申请人： Michael BIGGS , Roger STERN , Christopher DANEK
发明人： Michael BIGGS , Roger STERN , Christopher DANEK
IPC分类号： A61N1/00
CPC分类号： A61N1/06 , A61B18/14 , A61B2018/00541 , A61N1/40
摘要： The present invention includes a system for delivering energy to an airway wall of a lung comprising an energy delivering apparatus and a PID controller having one or more variable gain factors which are rest after energy deliver has begun. The energy delivering apparatus may include a flexible elongated member and a distal expandable basket having at least one electrode for transferring energy to the airway wall and at least one temperature sensor for measuring temperature. The PID controller determines a new power set point base on an error between a preset temperature and the measured temperature. The algorithm can be Pii+1=Pi+G(αei+βei-1+γei-2) where α, β and γ are preset values and a is from 1 to 2; β is from −1 to −2; and 7 is from −0.5 to 0-5. In another variation, the controller is configured to shut down if various measured parameters are exceeded such as, for example, energy, impedance, temperature, temperature differences, activation time and combinations thereof. Methods for treating a target medium using a PID algorithm are also provided.
摘要翻译：本发明包括一种用于向肺气道壁输送能量的系统，包括能量输送装置和具有一个或多个可变增益因子的PID控制器，所述可变增益因子在能量传递开始之后休息。能量输送装置可以包括柔性细长构件和远端可膨胀篮，其具有用于将能量传递到气道壁的至少一个电极和用于测量温度的至少一个温度传感器。 PID控制器根据预设温度和测量温度之间的误差确定新的功率设定点。该算法可以是Pi + i + 1 + P（i + 1）+＆Sigma; i = 其中α，β和γ是预设值，a是1至2; β为-1至-2; 7为-0.5〜0-5。在另一变型中，控制器被配置为如果超过各种测量参数，例如能量，阻抗，温度，温差，激活时间及其组合，则关闭。还提供了使用PID算法处理目标介质的方法。

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