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1. 发明申请

US20140350513A1 MULTI-SENSOR INFUSION SYSTEM FOR DETECTING AIR OR AN OCCLUSION IN THE INFUSION SYSTEM 审中-公开
标题翻译：用于检测输血系统中的空气或渗漏的多传感器输注系统
公开(公告)号：US20140350513A1
公开(公告)日：2014-11-27
申请号：US14285797
申请日：2014-05-23
申请人： Meriyan Oruklu , Timothy L. Ruchti , Paul T. Kotnik , Anatoly S. Belkin , Brian G. Markey
发明人： Meriyan Oruklu , Timothy L. Ruchti , Paul T. Kotnik , Anatoly S. Belkin , Brian G. Markey
IPC分类号： A61M5/168 , A61M5/50
CPC分类号： A61M5/16854 , A61M5/365 , A61M5/5086 , A61M2005/16863 , A61M2005/16868 , A61M2005/16872 , A61M2205/18 , A61M2205/3317 , A61M2205/332 , A61M2205/3331 , A61M2205/3351 , A61M2205/3355 , A61M2205/3576 , A61M2205/52
摘要： An infusion system for being operatively connected to a fluid delivery line and to an infusion container includes a pump, a plurality of different types of sensors connected to the pump or the fluid delivery line, at least one processor, and a memory. The plurality of different types of sensors are configured to indicate whether air is in the fluid delivery line. The memory includes programming code for execution by the at least one processor. The programming code is configured to, based on measurements taken by the plurality of different types of sensors, determine: whether there is air in the fluid delivery line; whether there is a partial occlusion or a total occlusion in the fluid delivery line; or a percentage of the air present in the fluid delivery line or the probability of the air being in the fluid delivery line.
摘要翻译：用于可操作地连接到流体输送管线和输注容器的输注系统包括泵，连接到泵或流体输送管线的多个不同类型的传感器，至少一个处理器和存储器。多个不同类型的传感器被配置为指示空气是否在流体输送管线中。存储器包括用于由至少一个处理器执行的编程代码。编程代码被配置为基于由多种不同类型的传感器所采取的测量来确定：流体输送管线中是否存在空气; 是否在流体输送管线中存在部分闭塞或完全闭塞; 或存在于流体输送管线中的空气的百分比或空气在流体输送管线中的可能性。

2. 发明申请

US20130261993A1 AIR DETECTION SYSTEM AND METHOD FOR DETECTING AIR IN A PUMP OF AN INFUSION SYSTEM 有权
标题翻译：用于检测输液系统中的空气的空气检测系统和方法
公开(公告)号：US20130261993A1
公开(公告)日：2013-10-03
申请号：US13851207
申请日：2013-03-27
申请人： Timothy L. Ruchti , Brian G. Markey , Anatoly S. Belkin , Paul T. Kotnik , Mohammed M. Khair
发明人： Timothy L. Ruchti , Brian G. Markey , Anatoly S. Belkin , Paul T. Kotnik , Mohammed M. Khair
IPC分类号： G01F1/74
CPC分类号： G01F1/74 , A61M5/16831 , A61M5/365 , A61M2205/331 , F04B43/0081 , F04B51/00
摘要： Various systems and methods for detecting air in a chamber of an infusion system are disclosed. In one embodiment, a determination is made that air is contained in the chamber on the basis of a change in the average force exerted against the plunger utilizing a derivative spike for event detection and a systematic reduction in the average force to confirm the nature of the change. In another embodiment, a determination is made that the chamber contains air when a difference between the current force profile and a baseline force profile crosses a threshold. In an additional embodiment, a force profile is classified as being an air force profile or a liquid force profile based on extracted features of the force profile.
摘要翻译：公开了用于检测输注系统的腔室中的空气的各种系统和方法。在一个实施例中，基于使用用于事件检测的导数尖峰对柱塞施加的平均力的变化，确定空气被容纳在腔室中，并且系统地减小平均力以确认更改。在另一个实施例中，当当前力分布和基线力分布之间的差异跨越阈值时，确定腔室包含空气。在另外的实施例中，基于所提取的力分布特征将力分布分类为空气分布或液体力分布。

3. 发明申请

US20130085443A1 Intravenous Flow Rate Controller 有权
标题翻译：静脉流量控制器
公开(公告)号：US20130085443A1
公开(公告)日：2013-04-04
申请号：US13631339
申请日：2012-09-28
申请人： Michael G. Lowery , Brian G. Markey , James A. Markey
发明人： Michael G. Lowery , Brian G. Markey , James A. Markey
IPC分类号： A61M39/22
CPC分类号： G05D7/0635 , A61M5/1411 , A61M5/1689 , A61M2205/215 , G01F1/56 , G01F1/72 , G01F3/00 , G01F22/00 , G06F19/00 , G06F19/3468 , G06T7/62 , G06T2207/20224
摘要： Tilting of a drip chamber from its vertical axis during fluid administration can have negative effects upon the accuracy of systems configured for drop counting and/or for volumetric measurement of individual drops passing through the drip chamber. To address these negative effects, in accordance with one embodiment of the present disclosure, a fluid delivery system engages in a fluid control process that comprises determining an error parameter, based at least in part on a tilt signal, generating an error condition, and either holding the fluid flow at the present rate or stopping the flow.
摘要翻译：在流体给药期间，从垂直轴倾斜滴液室可能会对配置用于滴定计量的系统的精确度和/或通过滴注室的各个液滴的体积测量产生负面影响。为了解决这些负面影响，根据本公开的一个实施例，流体输送系统参与流体控制过程，流体控制过程包括至少部分地基于倾斜信号确定误差参数，产生误差状况，以及以目前的速度保持流体流动或停止流动。

4. 发明授权

US09134736B2 Intravenous flow rate controller 有权
标题翻译：静脉流量控制器
公开(公告)号：US09134736B2
公开(公告)日：2015-09-15
申请号：US13631422
申请日：2012-09-28
申请人： Michael G. Lowery , Brian G. Markey , James A. McNeely
发明人： Michael G. Lowery , Brian G. Markey , James A. McNeely
IPC分类号： H04N7/18 , A61M31/00 , G05D7/06 , G01F3/00 , A61M5/14 , A61M5/168 , G01F1/56 , G01F1/72 , G01F22/00 , G06T7/60 , G06F19/00
CPC分类号： G05D7/0635 , A61M5/1411 , A61M5/1689 , A61M2205/215 , G01F1/56 , G01F1/72 , G01F3/00 , G01F22/00 , G06F19/00 , G06F19/3468 , G06T7/62 , G06T2207/20224
摘要： Tilting of a drip chamber from its vertical axis during fluid administration can have negative effects upon the accuracy of systems configured for drop counting and/or for volumetric measurement of individual drops passing through the drip chamber. To address these negative effects, in accordance with one embodiment of the present disclosure, a fluid delivery system that measures the flow volume of a fluid delivery system is disclosed, which includes an imaging apparatus that captures a first image of a drip chamber while a drop is falling therein and a second image of the drip chamber with no drop. Portions of each image that are in substantially the same position in each image are subtracted.
摘要翻译：在流体给药期间，从垂直轴倾斜滴液室可能会对配置用于滴定计量的系统的精确度和/或通过滴注室的各个液滴的体积测量产生负面影响。为了解决这些负面影响，根据本公开的一个实施例，公开了一种测量流体输送系统的流量的流体输送系统，其包括捕获滴液室的第一图像的成像装置，同时滴落在其中落下，滴液室的第二张图像不滴落。在每个图像中基本上相同位置的每个图像的部分被减去。

5. 发明授权

US5892234A Method for determining an unknown absorbed dose of radiation using optically stimulated luminescence 失效
标题翻译：使用光学刺激发光来确定辐射的未知吸收剂量的方法
公开(公告)号：US5892234A
公开(公告)日：1999-04-06
申请号：US710780
申请日：1996-09-20
申请人： Stephen W. S. McKeever , Mark S. Akselrod , Brian G. Markey
发明人： Stephen W. S. McKeever , Mark S. Akselrod , Brian G. Markey
IPC分类号： G01T1/10 , G01T1/105 , G01N21/64
CPC分类号： G01T1/10 , G01T1/105
摘要： A bimodal method for determining an unknown absorbed dose of radiation. An irradiated material is illuminated with ultraviolet or visible light and the luminescence which is emitted from the material is detected. The illuminating light is pulsed, with pulse widths varying from 1 ns to 500 ms. The luminescence emission from dosimetric traps is monitored after a delay following the end of the illumination pulse. The integrated luminescence signal is related to the initial absorbed dose of radiation and thus may be used to calculate the unknown absorbed dose after calibration. In a first mode, the material is completely detrapped--that is, all the dosimetric traps are emptied by the illumination beam. In a second mode the number of illumination pulses, each being followed by the time delay and by periods during which the luminescence signal is detected, is selected such that only a portion of the radiation-induced luminescence from the material is extracted.
摘要翻译：用于确定未知吸收辐射剂量的双峰方法。照射的材料用紫外线或可见光照射，并且检测从材料发射的发光。照明光被脉冲，脉冲宽度从1ns到500ms变化。在照射脉冲结束后的延迟后监测剂量测定阱的发光。集成的发光信号与辐射的初始吸收剂量有关，因此可用于计算校准后未知的吸收剂量。在第一模式中，材料被完全去除，也就是说，所有的剂量捕获器被照明光束排空。在第二模式中，选择每个跟随着时间延迟的照明脉冲的数量和检测发光信号的周期，使得仅提取来自材料的辐射诱发的发光的一部分。

6. 发明授权

US09134735B2 Intravenous flow rate controller 有权
标题翻译：静脉流量控制器
公开(公告)号：US09134735B2
公开(公告)日：2015-09-15
申请号：US13631339
申请日：2012-09-28
申请人： Michael G. Lowery , Brian G. Markey , James A. McNeely
发明人： Michael G. Lowery , Brian G. Markey , James A. McNeely
IPC分类号： A61M39/22 , G05D7/06 , G01F3/00 , A61M5/14 , A61M5/168 , G01F1/56 , G01F1/72 , G01F22/00 , G06T7/60 , G06F19/00
CPC分类号： G05D7/0635 , A61M5/1411 , A61M5/1689 , A61M2205/215 , G01F1/56 , G01F1/72 , G01F3/00 , G01F22/00 , G06F19/00 , G06F19/3468 , G06T7/62 , G06T2207/20224
摘要： Tilting of a drip chamber from its vertical axis during fluid administration can have negative effects upon the accuracy of systems configured for drop counting and/or for volumetric measurement of individual drops passing through the drip chamber. To address these negative effects, in accordance with one embodiment of the present disclosure, a fluid delivery system engages in a fluid control process that comprises determining an error parameter, based at least in part on a tilt signal, generating an error condition, and either holding the fluid flow at the present rate or stopping the flow.
摘要翻译：在流体给药期间，从垂直轴倾斜滴液室可能会对配置用于滴定计量的系统的精确度和/或通过滴注室的各个液滴的体积测量产生负面影响。为了解决这些负面影响，根据本公开的一个实施例，流体输送系统参与流体控制过程，流体控制过程包括至少部分地基于倾斜信号确定误差参数，产生误差状况，以及以目前的速度保持流体流动或停止流动。

7. 发明申请

US20150246175A1 INFUSION SYSTEM AND METHOD WHICH UTILIZES DUAL WAVELENGTH OPTICAL AIR-IN-LINE DETECTION 审中-公开
标题翻译：使用双波长光学空气在线检测的输注系统和方法
公开(公告)号：US20150246175A1
公开(公告)日：2015-09-03
申请号：US14633614
申请日：2015-02-27
申请人： Gary David Shubinsky , Tamas Ban , Brian G. Markey
发明人： Gary David Shubinsky , Tamas Ban , Brian G. Markey
IPC分类号： A61M5/14
CPC分类号： A61M5/14 , A61M5/16831 , A61M5/172 , A61M5/365 , A61M2205/3313 , A61M2205/50
摘要： Infusion fluid is flowed through a fluid delivery line of an infusion system. Optical signals having different wavelengths are transmitted through the fluid delivery line. The transmitted optical signals having the different wavelengths are received. At least one processor determines whether air or infusion fluid is disposed in the fluid delivery line based on the received optical signals having the different wavelengths.
摘要翻译：输液被流过输液系统的输液管线。具有不同波长的光信号通过流体输送管线传输。接收具有不同波长的透射光信号。至少一个处理器基于所接收的具有不同波长的光信号来确定空气或输液是否设置在流体输送管线中。

8. 发明申请

US20130083191A1 Intravenous Flow Rate Controller 有权
标题翻译：静脉流量控制器
公开(公告)号：US20130083191A1
公开(公告)日：2013-04-04
申请号：US13631422
申请日：2012-09-28
申请人： Michael G. Lowery , Brian G. Markey , James A. Markey
发明人： Michael G. Lowery , Brian G. Markey , James A. Markey
IPC分类号： H04N7/18
CPC分类号： G05D7/0635 , A61M5/1411 , A61M5/1689 , A61M2205/215 , G01F1/56 , G01F1/72 , G01F3/00 , G01F22/00 , G06F19/00 , G06F19/3468 , G06T7/62 , G06T2207/20224
摘要： Tilting of a drip chamber from its vertical axis during fluid administration can have negative effects upon the accuracy of systems configured for drop counting and/or for volumetric measurement of individual drops passing through the drip chamber. To address these negative effects, in accordance with one embodiment of the present disclosure, a fluid delivery system that measures the flow volume of a fluid delivery system is disclosed, which includes an imaging apparatus that captures a first image of a drip chamber while a drop is falling therein and a second image of the drip chamber with no drop. Portions of each image that are in substantially the same position in each image are subtracted.
摘要翻译：在流体给药期间，从垂直轴倾斜滴液室可能会对配置用于滴定计量的系统的精确度和/或通过滴注室的各个液滴的体积测量产生负面影响。为了解决这些负面影响，根据本公开的一个实施例，公开了一种测量流体输送系统的流量的流体输送系统，其包括捕获滴液室的第一图像的成像装置，同时滴落在其中落下，滴液室的第二张图像不滴落。在每个图像中基本上相同位置的每个图像的部分被减去。

9. 发明申请

US20130023792A1 AUTOMATED BLOOD SAMPLING SYSTEM AND METHOD 审中-公开
标题翻译：自动血液采样系统及方法
公开(公告)号：US20130023792A1
公开(公告)日：2013-01-24
申请号：US13552868
申请日：2012-07-19
申请人： Brian G. Markey , Michael G. Lowery
发明人： Brian G. Markey , Michael G. Lowery
IPC分类号： A61B5/157
CPC分类号： A61B5/155 , A61B5/14532 , A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150366 , A61B5/150389 , A61B5/150503 , A61B5/150755 , A61B5/150992 , A61B5/153 , A61B5/157 , F04C2270/041
摘要： Automated blood sampling systems and methods of use are disclosed which are configured to withdraw and test the blood of a mammal without clotting of the withdrawn blood in a main flow path of the automated blood sampling system. The automated blood sampling systems and methods do not require the use of an anti-blood-clotting solution or drug such as Heparin to avoid clotting of the blood in the main flow path of the automated blood sampling system.
摘要翻译：公开了自动血液取样系统和使用方法，其被配置为在自动采血系统的主流路中抽出和测试哺乳动物的血液而不使所抽取的血液凝结。自动采血系统和方法不需要使用抗血液凝固溶液或药物如肝素来避免血液在自动采血系统的主流路中凝血。

10. 发明授权

US5962857A Method for the fast determination of an unknown absorbed dose of radiation with high sensitivity using optically stimulated luminescence 失效
标题翻译：使用光学激发的发光快速测定具有高灵敏度的未知吸收剂量的辐射的方法
公开(公告)号：US5962857A
公开(公告)日：1999-10-05
申请号：US879385
申请日：1997-06-20
申请人： Stephen W. S. McKeever , Mark S. Akselrod , Brian G. Markey
发明人： Stephen W. S. McKeever , Mark S. Akselrod , Brian G. Markey
IPC分类号： G01T1/10 , G01T1/105
CPC分类号： G01T1/105 , G01T1/10
摘要： The optically stimulated luminescence generated from a luminescent material having a relatively long lifetime of luminescence is measured by using short pulses of laser light stimulation and detecting luminescence only between pulses of light stimulation and after a certain delay following the stimulation pulse.
摘要翻译：通过使用激光激光的短脉冲和仅在光刺激的脉冲之间和在刺激脉冲之后的一定延迟之后检测发光来测量由具有相对长的发光寿命的发光材料产生的光学刺激的发光。

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