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1. 发明申请

US20200268632A1 ANTI-AGING AGENT AND ANTI-AGING METHOD 审中-公开
公开(公告)号：US20200268632A1
公开(公告)日：2020-08-27
申请号：US16646578
申请日：2018-09-14
申请人： Megumi Tanaka , Tsunemaru Tanaka
发明人： Megumi Tanaka , Tsunemaru Tanaka
IPC分类号： A61K8/60 , A61K31/706 , A61K9/00 , A61Q19/00 , A61Q19/08
摘要： PROBLEM: To provide an anti-aging agent and a method for the anti-aging that are safe in long-term intake and ensures effective suppression of the progress of the aging.SOLUTION: Nicotinamide mononucleotide is contained as an active ingredient.

2. 发明申请

US20220095665A1 FOOD OR BEVERAGE FOR BABIES AND INFANTS, METHOD FOR IMPROVING INTESTINAL ENVIRONMENT OF BABY OR INFANT, AND METHOD FOR ENHANCING IMMUNITY OF BABY OR INFANT 有权
公开(公告)号：US20220095665A1
公开(公告)日：2022-03-31
申请号：US17310557
申请日：2020-08-20
申请人： Megumi Tanaka , Tsunemaru Tanaka
发明人： Megumi Tanaka , Tsunemaru Tanaka
IPC分类号： A23L33/00 , A23C9/18 , A23L33/145
摘要： PROBLEM: To provide a food, a drink, or the like for infant that allows improving an intestinal environment and enhancing an immune strength of an infant.
SOLUTION: A food or drink for infant containing an effective dose of nicotinamide mononucleotide.

3. 发明授权

US11219590B2 Anti-aging agent and anti-aging method 有权
公开(公告)号：US11219590B2
公开(公告)日：2022-01-11
申请号：US16646578
申请日：2018-09-14
申请人： Megumi Tanaka , Tsunemaru Tanaka
发明人： Megumi Tanaka , Tsunemaru Tanaka
IPC分类号： A61K8/60 , A61K31/706 , A61K9/00 , A61Q19/00 , A61Q19/08
摘要： PROBLEM: To provide an anti-aging agent and a method for the anti-aging that are safe in long-term intake and ensures effective suppression of the progress of the aging.
SOLUTION: Nicotinamide mononucleotide is contained as an active ingredient.

4. 发明申请

US20220031596A1 ANTI-AGING AGENT AND ANTI-AGING METHOD 有权
公开(公告)号：US20220031596A1
公开(公告)日：2022-02-03
申请号：US17276156
申请日：2019-09-12
申请人： Megumi Tanaka , Tsunemaru Tanaka
发明人： Megumi Tanaka , Tsunemaru Tanaka
IPC分类号： A61K8/67 , A61Q19/08
摘要： PROBLEM: To provide an anti-aging agent and a method for the anti-aging that are safe in long-term intake and ensures effective suppression of the progress of the aging.
SOLUTION: Nicotinamide mononucleotide is contained as an active ingredient.

5. 发明申请

US20210196612A1 COSMETIC COMPOSITION CONTAINING NICOTINAMIDE MONONUCLEOTIDE 有权
公开(公告)号：US20210196612A1
公开(公告)日：2021-07-01
申请号：US16755692
申请日：2018-10-16
申请人： Megumi Tanaka , Tsunemaru Tanaka
发明人： Megumi Tanaka , Tsunemaru Tanaka
IPC分类号： A61K8/67 , A61Q19/08 , A61Q19/00
摘要： PROBLEM: To provide a cosmetic composition that has a moisturizing effect that gives lasting moisture to a skin, an effect that prevents or improves aging symptoms, such as wrinkles and sags, and similar effect.
SOLUTION: Nicotinamide mononucleotide is contained in a cosmetic composition.

6. 发明授权

US10898738B2 Visual function printing agent, and method for improving visual functions 有权
公开(公告)号：US10898738B2
公开(公告)日：2021-01-26
申请号：US16332217
申请日：2017-09-13
申请人： Megumi Tanaka , Tsunemaru Tanaka
发明人： Megumi Tanaka , Tsunemaru Tanaka
IPC分类号： A61P27/02 , A61K9/00 , A61K31/706 , A61K31/7084
摘要： Provided herein are compositions and methods for improving a visual function, e.g., eyesight, eye strain, blurred vision, dry eye, retinal function, presbyopia, or Visual Display Terminal (VDT) syndrome, that is safe for long-term intake and ensures effective improvement of visual function. The compositions include a nicotinamide mononucleotide (structure shown below) as an active ingredient.

7. 发明授权

US07776329B2 Anti-glypican 3 antibody 有权
公开(公告)号：US07776329B2
公开(公告)日：2010-08-17
申请号：US10583795
申请日：2005-07-08
申请人： Kiyotaka Nakano , Takeshi Yoshino , Jun-Ichi Nezu , Hiroyuki Tsunoda , Tomoyuki Igawa , Hiroko Konishi , Megumi Tanaka , Izumi Sugo , Shigeto Kawai , Takahiro Ishiguro , Yasuko Kinoshita
发明人： Kiyotaka Nakano , Takeshi Yoshino , Jun-Ichi Nezu , Hiroyuki Tsunoda , Tomoyuki Igawa , Hiroko Konishi , Megumi Tanaka , Izumi Sugo , Shigeto Kawai , Takahiro Ishiguro , Yasuko Kinoshita
IPC分类号： C07K16/28 , C07H21/04 , C12N5/06 , C12P21/06
摘要： An antibody capable of binding to a specific region of glypican 3, as well as a humanized antibody created based on that antibody are disclosed. The anti-GPC3 antibody of the invention has a higher ADCC activity and CDC activity compared with those of a conventional antibody. The antibody of the present invention is useful as a cell growth inhibitor, an anticancer agent and an agent for diagnosis of cancers.

8. 发明授权

US4544837A Focus servo control device for an optical system having an initial focus locking operation 失效
标题翻译：具有初始聚焦锁定操作的光学系统的聚焦伺服控制装置
公开(公告)号：US4544837A
公开(公告)日：1985-10-01
申请号：US452456
申请日：1982-12-23
申请人： Megumi Tanaka , Ryuichi Naito
发明人： Megumi Tanaka , Ryuichi Naito
IPC分类号： G02B7/28 , G11B7/085 , G11B7/09 , G11B7/12
CPC分类号： G11B7/0908 , G11B7/0917 , G11B7/0945 , G11B2007/0919
摘要： A focus servo control device for an optical system having a focus servo loop including an objective lens movable between a nearest position and a farthest position relative to an object, and a focus error signal generator for producing a focus error signal including at least first and second in-focus signals, the first in-focus signal corresponding to a shorter one of two distance values between the objective lens and the object at which the first and second in-focus signals are generated and indicating a real in-focus state. The device is constructed to open the focus servo loop and move the objective lens from the farthest position to the nearest position, and then to move the objective lens from the nearest position to the farthest position, while monitoring the focus error signal, and closes the focus servo loop upon receipt of the first in-focus signal, thereby preventing a malfunction of the focus servo loop which might occur by locking the objective lens at a false in-focus position.
摘要翻译：一种用于光学系统的聚焦伺服控制装置，其具有聚焦伺服回路，该聚焦伺服回路包括可在相对于物体的最近位置和最远位置之间移动的物镜;以及聚焦误差信号发生器，用于产生至少包括第一和第二对焦信号，第一对焦信号对应于物镜和物体之间的两个距离值中较短的一个，在该物体处产生第一和第二对焦信号，并且指示实际的对焦状态。该设备被构造为打开聚焦伺服环路，将物镜从最远位置移动到最近的位置，然后将物镜从最近的位置移动到最远位置，同时监视聚焦误差信号，并关闭在接收到第一对焦信号时聚焦伺服回路，从而防止通过将物镜锁定在假对焦位置而可能发生的聚焦伺服环路的故障。

9. 发明申请

US20200009170A1 SLEEP DISPLAY AGENT PROPERTY AND METHOD FOR IMPROVING SLEEP DISORDERS 审中-公开
公开(公告)号：US20200009170A1
公开(公告)日：2020-01-09
申请号：US16332225
申请日：2016-09-13
申请人： Megumi Tanaka
发明人： Megumi Tanaka , Tsunemaru Tanaka
IPC分类号： A61K31/706 , A61P25/20
摘要： PROBLEM: To provide an improving agent and an improving method for a sleep disorder that is safe in long-term intake and ensures effective improvement of the sleep disorder.SOLUTION: Nicotinamide mononucleotide is contained as an active ingredient.

10. 发明申请

US20200009408A1 VISUAL FUNCTION PRINTING AGENT, AND METHOD FOR IMPROVING VISUAL FUNCTIONS 审中-公开
公开(公告)号：US20200009408A1
公开(公告)日：2020-01-09
申请号：US16332217
申请日：2017-09-13
申请人： Megumi Tanaka
发明人： Megumi Tanaka , Tsunemaru Tanaka
IPC分类号： A61P27/02 , A61K31/706 , A61K9/00 , A61K31/7084
摘要： PROBLEM: To provide an improving agent and an improving method for a visual function that is safe in long-term intake and ensures effective improvement of the visual function.SOLUTION: Nicotinamide mononucleotide is contained as an active ingredient.

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