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1. 发明申请

WO2007121139A2 IN VIVO LOCALIZATION AND TRACKING OF TISSUE PENETRATING CATHETERS USING MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：使用磁共振成像的组织穿刺导管的体内定位和跟踪
公开(公告)号：WO2007121139A2
公开(公告)日：2007-10-25
申请号：PCT/US2007/066242
申请日：2007-04-09
申请人： MEDTRONIC VASCULAR, INC. , MACAULAY, Patrick , NAYAK, Asha
发明人： MACAULAY, Patrick , NAYAK, Asha
CPC分类号： G01R33/287 , A61B5/02007 , A61B5/055 , A61B5/064 , A61B5/416 , A61B5/4839 , A61B5/6852 , A61B34/20 , A61B2034/107 , A61B2034/2051 , A61B2090/374 , A61M25/0029 , A61M25/007 , A61M25/0127 , A61M2025/0037 , A61M2025/0096
摘要： Magnetic resonance image (MRI) guided tissue penetrating catheters and their methods of use. One or more MRI apparatus (e.g., one or more coils) are positioned on or in a catheter device that includes a tissue penetrator that may be used to form a penetration tract from a body lumen in which the catheter is positioned to a target location outside of that body lumen. The MRI apparatus (e.g., coil(s)) is/are used in conjunction with an MRI imaging system to indicate the position and/or rotational orientation of the penetrating catheter within the subject's body.
摘要翻译：磁共振图像（MRI）引导组织穿透导管及其使用方法。一个或多个MRI装置（例如，一个或多个线圈）被定位在导管装置上或导管装置中，该导管装置包括组织穿透器，所述组织穿透器可用于形成来自体腔的穿透管，其中导管定位在外部的目标位置的体腔。 MRI装置（例如，线圈）与MRI成像系统结合使用以指示穿透导管在受检者体内的位置和/或旋转取向。

2. 发明申请

WO2009088783A2 OBSTRUCTION REMOVAL SYSTEM 审中-公开
标题翻译：取走系统
公开(公告)号：WO2009088783A2
公开(公告)日：2009-07-16
申请号：PCT/US2008/088234
申请日：2008-12-23
申请人： MEDTRONIC VASCULAR INC. , THOMPSON, Dustin , PERKINS, DH , JOHNSON, Jeremy , SILVER, Michele , MAUCH, Kevin , MACAULAY, Patrick
发明人： THOMPSON, Dustin , PERKINS, DH , JOHNSON, Jeremy , SILVER, Michele , MAUCH, Kevin , MACAULAY, Patrick
IPC分类号： A61B17/22 , A61B17/00 , A61B17/32 , A61B10/02
CPC分类号： A61B17/320758 , A61B10/0266 , A61B17/320708 , A61B17/320725 , A61B2010/0225 , A61B2017/00345 , A61B2017/00398 , A61B2017/00867 , A61B2017/320008 , A61B2017/320012 , A61B2017/32006 , A61B2017/320064 , A61B2017/320741
摘要： An obstruction removal system for percutaneous removal of clots or obstructions within the vascular system is disclosed. The obstruction removal system includes a multi-lumen catheter with a plurality of circulating capture devices attached to or integral with a drive belt. The circulating capture or interference devices affect removal of the clot or obstruction bit-by-bit through a series of passes. The obstruction removal system may include one or more drive mechanisms, such as a pulley system and/or a vacuum source and/or a pressurization source, on its proximal end for driving the drive belt and capture devices through the catheter in a circulating manner. The obstruction removal system may also include one or more cleaning mechanisms, such as a vacuum chamber and/or a fluid rinse chamber, for removing the captured clot pieces from the capture devices.
摘要翻译：公开了一种用于经皮去除血管系统内的血块或障碍物的阻塞去除系统。阻塞去除系统包括多腔导管，其具有附接到驱动带或与传动带一体的多个循环捕获装置。循环捕获或干扰装置通过一系列通路影响凝块的清除或逐位阻塞。障碍物移除系统可以在其近端包括一个或多个驱动机构，例如皮带轮系统和/或真空源和/或加压源，用于驱动驱动带并以循环方式通过导管捕获装置。阻塞去除系统还可以包括一个或多个清洁机构，例如真空室和/或流体冲洗室，用于从捕获装置移除捕获的凝块。

3. 发明申请

WO2009131774A2 DEVICES AND METHODS FOR CONTROLLED-DEPTH INJECTION 审中-公开
标题翻译：控制深度注射的装置和方法
公开(公告)号：WO2009131774A2
公开(公告)日：2009-10-29
申请号：PCT/US2009/037573
申请日：2009-03-18
申请人： MEDTRONIC VASCULAR INC. , MACAULAY, Patrick , NAYAK, Asha , THOMPSON, Dustin
发明人： MACAULAY, Patrick , NAYAK, Asha , THOMPSON, Dustin
IPC分类号： A61M5/315 , A61M5/178 , A61M5/32
CPC分类号： A61B17/3478 , A61B2017/00247 , A61B2018/00392 , A61B2090/034 , A61M5/46
摘要： Devices and methods for limiting the depth to which a penetrator is advanced into an organ or mass of tissue. The device generally comprises a first member and a second member. The penetrator is attached to and extends from a second member. The first member has a penetrator shroud and a hollow bore extending therethrough. The second member is engageable with the first member such that a distal portion of the penetrator extends through the penetrator shroud. The distance to which the penetrator protrudes out of and beyond the distal end of the penetrator shroud is adjustable in accordance with the desired depth of penetration. The penetrator may then be advanced into the organ or tissue mass until the distal end of the shroud abuts against the organ or tissue mass, thereby stopping further advancement of the penetrator. The penetrator may have one or more lumen(s) for aspirating or infusing substances.
摘要翻译：用于限制穿透器进入器官或组织块的深度的装置和方法。该装置通常包括第一构件和第二构件。穿透器附接到第二构件并从第二构件延伸。第一构件具有穿透器护罩和延伸穿过其中的中空孔。第二构件可与第一构件接合，使得穿透器的远端部分延伸穿过穿透器护罩。穿透器突出到穿透器护罩的远端之外的距离可以根据期望的穿透深度进行调节。然后穿透器可以推进到器官或组织块中，直到护罩的远端抵靠器官或组织块，从而停止穿透器的进一步前进。穿透器可以具有用于吸入或输注物质的一个或多个内腔。

4. 发明申请

WO2009131773A2 DEVICES AND METHODS FOR CONTROLLED-DEPTH INJECTION 审中-公开
标题翻译：控制深度注射的装置和方法
公开(公告)号：WO2009131773A2
公开(公告)日：2009-10-29
申请号：PCT/US2009/037561
申请日：2009-03-18
申请人： MEDTRONIC VASCULAR INC. , THOMPSON, Dustin , MACAULAY, Patrick
发明人： THOMPSON, Dustin , MACAULAY, Patrick
IPC分类号： A61M5/19 , A61M5/315 , A61M5/178 , A61M5/20
CPC分类号： A61M5/19 , A61B17/00491 , A61B2017/00495 , A61B2017/00685 , A61B2017/2925 , A61M5/16827 , A61M5/31511
摘要： Devices and methods for simultaneous injection or delivery of two or more substances from separate syringes. The syringes are loaded into a device that has a handle and a screw driven mechanism for simultaneously depressing the plungers of the syringes. The user grasps the handle and positions the device. Thereafter, the screw mechanism is used to simultaneously advance the plungers of the syringes thereby simultaneously expelling the substances from the syringes.
摘要翻译：从单独的注射器同时注射或递送两种或多种物质的装置和方法。将注射器装载到具有手柄和螺杆驱动机构的装置中，以同时按压注射器的柱塞。用户抓住手柄并对设备进行定位。此后，螺杆机构用于同时推进注射器的柱塞，从而同时从注射器排出物质。

5. 发明申请

WO2007121143A2 MICROCATHETER DEVICES AND METHODS FOR TARGETED SUBSTANCE DELIVERY 审中-公开
标题翻译： MICROCATHETER设备和目标物质运输方法
公开(公告)号：WO2007121143A2
公开(公告)日：2007-10-25
申请号：PCT/US2007/066246
申请日：2007-04-09
申请人： MEDTRONIC VASCULAR, INC. , LAMSOM, Theodore , MACAULAY, Patrick
发明人： LAMSOM, Theodore , MACAULAY, Patrick
CPC分类号： A61M25/007 , A61B18/1477 , A61B2017/00247 , A61B2018/00392 , A61B2018/1425 , A61M5/3286 , A61M5/3291 , A61M25/0068 , A61M25/0069 , A61M25/0082 , A61M25/0084 , A61M2025/0042 , A61M2025/0092 , A61M2025/0096
摘要： Delivery catheters useable to deliver substances, articles or devices to target locations within the bodies of human or animal subjects. The delivery catheter generally comprises a catheter having a tissue penetrating distal tip member on the distal end and one or more delivery aperture(s) whereby a substance, article or device may be delivered through the lumen of the catheter body and out of the delivery aperture(s). In some applications, the substance delivery catheter is used in combination with a transluminal tissue penetrating catheter having a penetrator that is advanced to a first location. The delivery catheter is then advanced through (or over) the penetrator, through intervening tissue, to a desired target location.
摘要翻译：输送导管可用于将物质，物品或装置输送到目标人体或动物体内的位置。输送导管通常包括导管，该导管具有远端上的组织穿透远侧末端构件和一个或多个输送孔，从而可将物质，制品或装置通过导管主体的内腔输送出输送孔（S）。在一些应用中，物质输送导管与具有前进到第一位置的穿透器的经管组织穿透导管组合使用。然后将输送导管穿过（或越过）穿透器通过介入组织推进到期望的目标位置。

6. 发明公开

EP2012666A2 IN VIVO LOCALIZATION AND TRACKING OF TISSUE PENETRATING CATHETERS USING MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：体内检测和组织的调查尿急导管磁成像手段
公开(公告)号：EP2012666A2
公开(公告)日：2009-01-14
申请号：EP07760326.4
申请日：2007-04-09
申请人： Medtronic Vascular, Inc.
发明人： MACAULAY, Patrick , NAYAK, Asha
IPC分类号： A61B5/06 , A61M25/00 , A61B5/055 , A61M25/01 , G01R33/28
CPC分类号： G01R33/287 , A61B5/02007 , A61B5/055 , A61B5/064 , A61B5/416 , A61B5/4839 , A61B5/6852 , A61B34/20 , A61B2034/107 , A61B2034/2051 , A61B2090/374 , A61M25/0029 , A61M25/007 , A61M25/0127 , A61M2025/0037 , A61M2025/0096
摘要： Magnetic resonance image (MRI) guided tissue penetrating catheters (10). One or more MRI apparatus (34,35,46) (e.g., one or more coils) are positioned on or in a catheter device that includes a tissue penetrator (30) that may be used to form a penetration tract from a body lumen in which the catheter is positioned to a target location outside of that body lumen. The MRI apparatus (e.g., coil(s) ) is/are used in conjunction with an MRI imaging system to indicate the position and/or rotational orientation of the penetrating catheter within the subject's body.

7. 发明公开

EP2279020A2 DEVICES AND METHODS FOR CONTROLLED-DEPTH INJECTION 有权
标题翻译： DEVICES AND METHOD FOR受控注射深度
公开(公告)号：EP2279020A2
公开(公告)日：2011-02-02
申请号：EP09734167.1
申请日：2009-03-18
申请人： Medtronic Vascular Inc.
发明人： THOMPSON, Dustin , MACAULAY, Patrick
IPC分类号： A61M5/19 , A61M5/315 , A61M5/178 , A61M5/20
CPC分类号： A61M5/19 , A61B17/00491 , A61B2017/00495 , A61B2017/00685 , A61B2017/2925 , A61M5/16827 , A61M5/31511
摘要： Devices and methods for simultaneous injection or delivery of two or more substances from separate syringes. The syringes are loaded into a device that has a handle and a screw driven mechanism for simultaneously depressing the plungers of the syringes. The user grasps the handle and positions the device. Thereafter, the screw mechanism is used to simultaneously advance the plungers of the syringes thereby simultaneously expelling the substances from the syringes.

8. 发明授权

EP2010263B1 MICROCATHETER DEVICES AND METHODS FOR TARGETED SUBSTANCE DELIVERY 有权
标题翻译：微导管装置和有针对性的主动释放方法
公开(公告)号：EP2010263B1
公开(公告)日：2010-06-16
申请号：EP07760330.6
申请日：2007-04-09
申请人： Medtronic Vascular Inc.
发明人： LAMSOM, Theodore , MACAULAY, Patrick
IPC分类号： A61M25/00
CPC分类号： A61M25/007 , A61B18/1477 , A61B2017/00247 , A61B2018/00392 , A61B2018/1425 , A61M5/3286 , A61M5/3291 , A61M25/0068 , A61M25/0069 , A61M25/0082 , A61M25/0084 , A61M2025/0042 , A61M2025/0092 , A61M2025/0096
摘要： Delivery catheters useable to deliver substances, articles or devices to target locations within the bodies of human or animal subjects. The delivery catheter generally comprises a catheter having a tissue penetrating distal tip member on the distal end and one or more delivery aperture(s) whereby a substance, article or device may be delivered through the lumen of the catheter body and out of the delivery aperture(s). In some applications, the substance delivery catheter is used in combination with a transluminal tissue penetrating catheter having a penetrator that is advanced to a first location. The delivery catheter is then advanced through (or over) the penetrator, through intervening tissue, to a desired target location.

9. 发明公开

EP2010263A2 MICROCATHETER DEVICES AND METHODS FOR TARGETED SUBSTANCE DELIVERY 有权
标题翻译：微导管装置和有针对性的主动释放方法
公开(公告)号：EP2010263A2
公开(公告)日：2009-01-07
申请号：EP07760330.6
申请日：2007-04-09
申请人： Medtronic Vascular Inc.
发明人： LAMSOM, Theodore , MACAULAY, Patrick
IPC分类号： A61M25/00
CPC分类号： A61M25/007 , A61B18/1477 , A61B2017/00247 , A61B2018/00392 , A61B2018/1425 , A61M5/3286 , A61M5/3291 , A61M25/0068 , A61M25/0069 , A61M25/0082 , A61M25/0084 , A61M2025/0042 , A61M2025/0092 , A61M2025/0096
摘要： Delivery catheters useable to deliver substances, articles or devices to target locations within the bodies of human or animal subjects. The delivery catheter generally comprises a catheter having a tissue penetrating distal tip member on the distal end and one or more delivery aperture(s) whereby a substance, article or device may be delivered through the lumen of the catheter body and out of the delivery aperture(s). In some applications, the substance delivery catheter is used in combination with a transluminal tissue penetrating catheter having a penetrator that is advanced to a first location. The delivery catheter is then advanced through (or over) the penetrator, through intervening tissue, to a desired target location.

10. 发明公开

EP2249713A2 OBSTRUCTION REMOVAL SYSTEM 审中-公开
标题翻译：系统脱除障碍物
公开(公告)号：EP2249713A2
公开(公告)日：2010-11-17
申请号：EP08869656.2
申请日：2008-12-23
申请人： Medtronic Vascular Inc.
发明人： THOMPSON, Dustin , PERKINS, DH , JOHNSON, Jeremy , SILVER, Michele , MAUCH, Kevin , MACAULAY, Patrick
IPC分类号： A61B17/22 , A61B17/00 , A61B17/32 , A61B10/02
CPC分类号： A61B17/320758 , A61B10/0266 , A61B17/320708 , A61B17/320725 , A61B2010/0225 , A61B2017/00345 , A61B2017/00398 , A61B2017/00867 , A61B2017/320008 , A61B2017/320012 , A61B2017/32006 , A61B2017/320064 , A61B2017/320741
摘要： An obstruction removal system (100) for percutaneous removal of clots or obstructions within the vascular system is disclosed. The obstruction removal system (100) includes a multi-lumen catheter (102) with a plurality of circulating capture devices (114) attached to or integral with a drive belt (112). The circulating capture or interference devices (114) affect removal of the clot or obstruction bit-by-bit through a series of passes. The obstruction removal system (100) may include one or more drive mechanisms (116), such as a pulley system and/or a vacuum source and/or a pressurization source, on its proximal end for driving the drive belt (112) and capture devices (114) through the catheter (102) in a circulating manner. The obstruction removal system (100) may also include one or more cleaning mechanisms, such as a vacuum chamber and/or a fluid rinse chamber, for removing the captured clot pieces from the capture devices (114).

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