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1. 发明授权

EP1020495B1 ION COMPLEX, COATING MATERIAL, AND COATING METHOD 有权
标题翻译：离子复合物，涂层材料及涂装工艺
公开(公告)号：EP1020495B1
公开(公告)日：2004-09-22
申请号：EP99933116.8
申请日：1999-07-27
申请人： Mebiol Inc. , TERUMO KABUSHIKI KAISHA
发明人： YOSHIOKA, Hiroshi , MORI, Yuichi , KUBOTA, Sunao
IPC分类号： C08L101/00 , C09D201/00 , A61L33/00 , C09D201/02 , C09D105/10
CPC分类号： A61L33/00 , A61L33/0011 , A61L33/0035 , A61L33/062 , C09D201/02 , Y10T428/31 , Y10T428/31504 , Y10T428/31855
摘要： An ion complex which comprises a water-insoluble polyion (P) and a water-soluble polyion (A) and which is insoluble in water and soluble in water-containing organic solvents. The ion complex is suitable for use as a coating material to be applied to various ionic substances (e.g., a substance having physiological activity such as anticoagulant or antibacterial activity).

2. 发明申请

WO2006103685A2 A METHOD FOR CULTIVATING CELLS DERIVED FROM CORNEAL LIMBAL TISSUE AND CELLS DEIVED FROM CORNEAL LIMBAL TISSUE 审中-公开
标题翻译：用于培养从角膜组织和从角膜组织中分离的细胞产生的细胞的方法
公开(公告)号：WO2006103685A2
公开(公告)日：2006-10-05
申请号：PCT/IN2005/000092
申请日：2005-03-28
申请人： VISION RESEARCH FOUNDATION , NICHI-IN-DRUGS & DEVICES (P) LTD. , MEBIOL INC.
发明人： MADHAVAN, Hajib, Naraharirao , JEBAKUMAR, Abraham, Samuel , MORI, Yuichi , YOSHIOKA, Hiroshi
IPC分类号： C12N5/06
CPC分类号： C12N5/0623 , C12N5/0621 , C12N2533/30
摘要： The present inventors have found that corneal limbal stem cells, which can be used to treat diseases associated with cornea can be obtained by a method for cultivating corneal limbal stem cells characterized in that the method comprises the steps of: embedding the corneal limbal tissue within an aqueous solution in a low temperature sol state wherein the aqueous solution contains at least a hydrogel-forming polymer showing thereto-reversible sol-gel transition and wherein the aqueous solution is in a sol state at a low temperature and is in a gel state at a high temperature; heating the said aqueous solution to cultivate the said corneal limbal tissue within the said hydrogel in a high temperature gel state so that the corneal limbal stem cells spread and grow outside of the said corneal limbal tissue; cooling the said hydrogel to return from the gel state to a low temperature sol state; and collecting the spread and grown cells derived from corneal limbal tissue.
摘要翻译：本发明人已经发现，可用于治疗与角膜相关的疾病的角膜缘干细胞可以通过培养角膜缘干细胞的方法获得，其特征在于该方法包括以下步骤：将角膜缘膜组织嵌入到水溶液，其中所述水溶液含有至少一种显示其可逆的溶胶 - 凝胶转变的水凝胶形成聚合物，并且其中所述水溶液在低温下处于溶胶状态，并且处于凝胶状态高温; 加热所述水溶液以在高温凝胶状态下在所述水凝胶内培养所述角膜缘膜组织，使得角膜缘干细胞在所述角膜缘组织外展开并生长; 冷却所述水凝胶以从凝胶状态返回到低温溶胶状态; 并收集衍生自角膜缘膜组织的扩散和生长的细胞。

3. 发明公开

EP2064942A1 PLANT CULTIVATION SYSTEM 有权
标题翻译： PFLANZENANBAUSYSTEM UNDOVERHREN
公开(公告)号：EP2064942A1
公开(公告)日：2009-06-03
申请号：EP07828221.7
申请日：2007-09-10
申请人： Mebiol Inc.
发明人： OKAMOTO, Akihiro , FUJII, Manabu , YOSHIOKA, Hiroshi , MORI, Yuichi
IPC分类号： A01G27/00 , A01G1/00 , A01G7/00 , A01G13/00 , A01G25/00
CPC分类号： A01G31/02 , Y02P60/216
摘要： [Problems] To provide a system for producing safe and high nutrition vegetables at low cost. [Means to solve the problems] A plant cultivation system for cultivating a plant on a nonporous hydrophilic film, which comprises a nonporous hydrophilic film and a feeding means for supplying water or a nutrient fluid to the lower surface of the film in the absence of a hydroponic tank for accommodating water or a nutrient fluid and cultivating a plant therein. As the feeding means, use is made of a water absorbing material which is in contact with the film and which is disposed between the film and a water impermeable material. A system for producing safe and high nutrition vegetables at low cost can be obtained by disposing the water impermeable material directly on ground soil, whereupon the water absorbing material and an irrigation tube are disposed, followed by disposing the film thereon.
摘要翻译： [问题]提供低成本生产安全，高营养蔬菜的制度。解决问题的手段用于在无孔亲水膜上培养植物的植物栽培系统，其包含无孔亲水膜和用于在不存在的情况下向膜的下表面供应水或营养液的进料装置用于容纳水或营养液的水培罐，并在其中培养植物。作为进料装置，使用与膜接触并且设置在膜和不透水材料之间的吸水材料。通过将不透水材料直接放置在地面土壤上，由此设置吸水材料和冲洗管，然后在其上设置薄膜，可以获得低成本生产安全和高营养蔬菜的系统。

4. 发明授权

EP1145621B8 WATER-HOLDING CARRIERS FOR PLANTS AND WATER-HOLDING MATERIALS FOR GROWING PLANTS 有权
标题翻译：水托架保持为PFLANZENZUCHT布站和水利STOP END
公开(公告)号：EP1145621B8
公开(公告)日：2008-10-15
申请号：EP99954416.6
申请日：1999-11-05
申请人： Mebiol Inc. , Sanyo Chemical Industries, Ltd.
发明人： OBONAI, Yasuhiro, Mukoyama Orchids Ltd. , FURUKAWA, Koji, Mukoyama Orchids Ltd. , YOSHIOKA, Hiroshi , MORI, Yuichi , KASUYA, Kazuhiro, Sanyo Chem Ind. Ltd.
IPC分类号： A01G1/00
CPC分类号： A01G24/00 , A01G24/35
摘要： A water-retaining support for plants comprising a hydrogel-forming polymer (A) having a calcium ion absorption of 0-100 mg per 1 g of the dry weight thereof, having a chlorine ion content of 0.07-7 mmol per 1 g of the dry weight thereof and having a water absorption magnification in ion-exchange water at 25 DEG C of 1.0 x 10 to 1.0 x 10 ; or a plant body-growing water-retaining material comprising a molded product of a mixture of such a polymer (A) and a plant body-growing support (B). The water-retaining support for plants and the plant body-growing water-retaining material are those which have an excellent water-retaining property and they substantially do not cause inhibition of root generation or inhibition of root elongation.

5. 发明公开

EP1020495A1 ION COMPLEX, COATING MATERIAL, AND COATING METHOD 有权
标题翻译：离子复合物，涂层材料及涂装工艺
公开(公告)号：EP1020495A1
公开(公告)日：2000-07-19
申请号：EP99933116.8
申请日：1999-07-27
申请人： M & M Laboratory Co., Ltd. , TERUMO KABUSHIKI KAISHA
发明人： YOSHIOKA, Hiroshi , MORI, Yuichi , KUBOTA, Sunao
IPC分类号： C08L101/00 , C09D201/00 , A61L33/00
CPC分类号： A61L33/00 , A61L33/0011 , A61L33/0035 , A61L33/062 , C09D201/02 , Y10T428/31 , Y10T428/31504 , Y10T428/31855
摘要： An ion complex which comprises a water-insoluble polyion (P) and a water-soluble polyion (A); and is insoluble in water and soluble in an aqueous organic solvent. Such an ion complex becomes a coating material which can preferably be used for coating of various ionic substances (e.g., substance having biological activity such as an anticoagulant property or an antibacterial property).

6. 发明授权

EP3036988B1 PLANT CULTIVATION SYSTEM AND PLANT CULTIVATION METHOD 有权
公开(公告)号：EP3036988B1
公开(公告)日：2019-04-24
申请号：EP14837962.1
申请日：2014-08-11
申请人： Mebiol Inc.
发明人： YOSHIOKA, Hiroshi , MORI, Yuichi , OKAMOTO, Akihiro , MIURA, Shigeki , MIZUTANI, Tomoyoshi
IPC分类号： A01G31/02 , A01G31/00

7. 发明授权

EP2064942B1 PLANT CULTIVATION SYSTEM AND METHOD 有权
标题翻译：植物生长系统及方法
公开(公告)号：EP2064942B1
公开(公告)日：2016-10-26
申请号：EP07828221.7
申请日：2007-09-10
申请人： Mebiol Inc.
发明人： OKAMOTO, Akihiro , FUJII, Manabu , YOSHIOKA, Hiroshi , MORI, Yuichi
IPC分类号： A01G27/00 , A01G1/00 , A01G7/00 , A01G13/00 , A01G25/00 , A01G31/02
CPC分类号： A01G31/02 , Y02P60/216

8. 发明公开

EP1416044A1 SUPPORT FOR CELL / TISSUE CULTURE AND CULTURE METHOD 审中-公开
标题翻译： ZELLKULTUR- / GEWEBEKULTUR-TRÄGERUND KULTIVIERUNGSVERFAHREN
公开(公告)号：EP1416044A1
公开(公告)日：2004-05-06
申请号：EP02746025.2
申请日：2002-07-12
申请人： Mebiol Inc.
发明人： YOSHIOKA, Hiroshi , KUBOTA, Sunao , MORI, Yuichi
IPC分类号： C12N5/06 , C12M1/00
CPC分类号： C12N5/0068 , C12N2533/30
摘要： A cell or tissue-culturing carrier which can effectively regenerate an intended a cell or tissue, while suppressing an excessive growth of fibroblasts, and a method of culturing a cell or tissue by using the above carrier. the cell or tissue-culturing carrier wherein fibroblasts showing substantially no growing property in a gel based on the hydrogel-forming polymer, is constituted by using a hydrogel-forming polymer; an aqueous solution of which shows a thermo-reversible sol-gel transition such that it assumes a sol state at a lower temperature and assumes a gel state at a higher temperature.
摘要翻译：含有至少含有水凝胶形成聚合物的细胞和组织的支持是新的，其在低温下以溶胶形式出现，而在高温下作为凝胶显示热可逆溶胶 - 凝胶转移。由于构成的水凝胶形成聚合物，成纤维细胞在凝胶中不会增殖。对于细胞和组织的培养方法，通过使用载体还包括将细胞或组织在溶胶 - 凝胶转移的溶胶状态下在低温下加入到载体中的独立权利要求，在凝胶中在高温下培养状态，并且当支持体再次进行溶胶 - 凝胶转移时，在低温下以溶胶状态培养后的细胞或组织回收。

9. 发明公开

EP1407791A1 MATERIAL FOR TISSUE/ORGAN REGENERATION AND METHOD OF TISSUE/ORGAN REGENERATION 审中-公开
标题翻译：材料组织器官再生以及织物的器官再生程序
公开(公告)号：EP1407791A1
公开(公告)日：2004-04-14
申请号：EP02746014.6
申请日：2002-07-12
申请人： Mebiol Inc.
发明人： YOSHIOKA, Hiroshi , KUBOTA, Sunao , MORI, Yuichi , NOISHIKI, Yasuharu
IPC分类号： A61L27/52 , A61L27/54
CPC分类号： A61L27/54 , A61L27/38 , A61L27/52 , A61L2300/412 , A61L2300/414 , A61L2300/43 , A61L2300/602
摘要： A tissue or organ regeneration material which can easily be placed in a necrotic area or defective space of a tissue or organ in a living body, while suppressing an excessive growth of fibroblasts, to thereby effectively regenerate an intended tissue or organ, and a method of regenerating a tissue or organ by using the above material. The tissue or organ regeneration material wherein fibroblasts shows substantially no growing property in a gel based on the hydrogel-forming polymer is constituted by using a hydrogel-forming polymer, an aqueous solution of which shows a thermo-reversible sol-gel transition such that it assumes a sol state at a lower temperature and assumes a gel state at a higher temperature.
摘要翻译：组织和器官再生的材料包括水凝胶形成材料这表明可逆溶胶 - 凝胶转变表示在低温和凝胶状态在较高温度下的溶胶状态，和成纤维细胞将不会在基于聚合物凝胶增殖。因此独立权利要求中包括了（1）组织和细胞的培养其中具有酚红（PR），甲基蓝（MB）和绿色miogro（原文如此）（MG）的膨胀系数比作为测试载体（DPR / DMB）-2和DPR / DMG 1.2和（2）通过将材料注射到其中具有组织缺损部分再生组织和器官的方法。

10. 发明授权

EP2064942B9 PLANT CULTIVATION SYSTEM AND METHOD 有权
标题翻译：植物生长系统及方法
公开(公告)号：EP2064942B9
公开(公告)日：2017-01-25
申请号：EP07828221.7
申请日：2007-09-10
申请人： Mebiol Inc.
发明人： OKAMOTO, Akihiro , FUJII, Manabu , YOSHIOKA, Hiroshi , MORI, Yuichi
IPC分类号： A01G27/00 , A01G1/00 , A01G7/00 , A01G13/00 , A01G25/00 , A01G31/02
CPC分类号： A01G31/02 , Y02P60/216

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