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1. 发明公开

US20240183771A1 Method and apparatus for spatially manipulating at least one particle in a fluid, computer program product and computer-readable storage medium 审中-公开
公开(公告)号：US20240183771A1
公开(公告)日：2024-06-06
申请号：US18574608
申请日：2021-07-30
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V.
发明人： Elena Erben , Nicola Maghelli , Moritz Kreysing
IPC分类号： G01N15/1409 , B01L3/00 , G01N15/1434 , G02B21/32 , G01N15/1404
CPC分类号： G01N15/1409 , B01L3/502761 , G01N15/1434 , G02B21/32 , B01L2200/0663 , B01L2200/0668 , B01L2200/143 , B01L2300/1872 , B01L2400/0445 , B01L2400/0451 , G01N2015/1413
摘要： The invention concerns a method for spatially manipulating at least one particle in a fluid, wherein the particle or the particles is/are spatially manipulated in the fluid by hydrodynamic flows which are generated in the fluid by means of dynamic localized heating of the fluid. The method according to the invention is characterized in that at least one target spatial configuration of the particle(s) in the fluid is defined and that the following further steps are carried out: a) an actual spatial configuration of the particle(s) is captured, b) a specific dynamic localized heating event to be applied to the fluid is determined in dependence of at least one recent actual spatial configuration of the particle(s) and a target configuration of the particle(s), c) the specific dynamic localized heating as determined in step c) is applied at least once to the fluid and d) at least one or all of the steps a) to c) are repeated. The invention concerns furthermore an apparatus for spatially manipulating at least one particle in a fluid by means of hydrodynamic flows a computer program product and a computer-readable storage medium.

2. 发明授权

US11803046B2 Apparatus and method for simultaneous imaging and execution of contact-free directed hydrodynamic flow 有权
公开(公告)号：US11803046B2
公开(公告)日：2023-10-31
申请号：US16766456
申请日：2018-11-23
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V.
发明人： Moritz Kreysing , Anatol Fritsch , Matthaeus Mittasch
IPC分类号： G02B21/36 , G02B21/02 , G02B21/08 , G02B21/28 , G02B21/30 , G01N21/64 , B01L3/00 , G02B21/00 , G01N15/00
CPC分类号： G02B21/36 , B01L3/50273 , G02B21/0032 , G02B21/02 , G02B21/08 , G02B21/28 , G02B21/30 , B01L3/5027 , B01L2400/0463 , G01N21/6458 , G01N2015/0065
摘要： An apparatus and method for simultaneous imaging and execution of contact-free directed hydrodynamic flow in a specimen. The apparatus includes a laser adapted to dynamically heat the specimen, a microscope with an objective adapted to image at least a part of the specimen and to guide a light beam of the laser into and/or onto the specimen to heat at least one specified location of the specimen, means for manipulating the specified location, and a sample chamber for the specimen that is accessible for imaging radiation and the light beam to allow simultaneous imaging and manipulation of the sample via the objective.

3. 发明公开

US20240241032A1 Method and apparatus for measuring a force on at least one particle in a fluid, computer program product and computer-readable storage medium 审中-公开
公开(公告)号：US20240241032A1
公开(公告)日：2024-07-18
申请号：US18574585
申请日：2021-07-30
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V.
发明人： Iliya Stoev , Nicola Maghelli , Moritz Kreysing
IPC分类号： G01N15/1434 , G01N15/1404 , G01N15/1429
CPC分类号： G01N15/1434 , G01N15/1404 , G01N15/1429 , G01N2015/1413 , G01N2015/1415 , G01N2015/1445
摘要： The invention concerns a method for measuring a force on at least one particle in a fluid wherein an inhomogeneous field of hydrodynamic flows is generated in a fluid by specific dynamic localized heating events, the particle is spatially manipulated by the hydrodynamic flows, a spatial configuration of the particle(s) within the fluid is captured and at least one force acting on the particle(s) is determined by evaluating the captured spatial configuration of the particle(s). The invention concerns furthermore an apparatus for measuring a force on at least one particle in a fluid, a computer program product, and a computer-readable storage medium.

4. 发明公开

US20240142761A1 Apparatus and Method for Simultaneous Imaging and Execution of Contact-Free Directed Hydrodynamic Flow 审中-公开
公开(公告)号：US20240142761A1
公开(公告)日：2024-05-02
申请号：US18497032
申请日：2023-10-30
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V.
发明人： Moritz Kreysing , Anatol Fritsch , Matthaeus Mittasch
IPC分类号： G02B21/36 , B01L3/00 , G02B21/00 , G02B21/02 , G02B21/08 , G02B21/28 , G02B21/30
CPC分类号： G02B21/36 , B01L3/50273 , G02B21/0032 , G02B21/02 , G02B21/08 , G02B21/28 , G02B21/30 , B01L2400/0463 , G01N21/6458
摘要： The present invention relates to an apparatus for simultaneous imaging and execution of contact-free directed hydrodynamic flow in a specimen with at least one light source, in particular a laser, adapted to dynamically heat the interior and/or a surface of the specimen, a microscope with an objective adapted to image at least a part of the specimen and to guide, in particular focus, a light beam of the light source, in particular a laser beam, into and/or onto the specimen to heat at least one specified location of the specimen, means for manipulating the specified location, and a sample chamber for the specimen that is accessible for imaging radiation and the light beam to allow simultaneous imaging and manipulation of the sample via the objective. Furthermore the present invention is directed to a method for simultaneous imaging and executing contact-free directed hydrodynamic flow in a specimen wherein, at least one light source, in particular a laser, dynamically heats the interior and/or a surface of the specimen via a light beam, in particular via a laser beam, the beam of the at least one light source is directed to the specimen through an objective of a microscope, the light beam is variably guided, in particular focused, to specified locations of the specimen inducing a hydrodynamic flow in the specimen, and imaging the specimen via the same objective as used for introduction of the light beam.

5. 发明授权

US11170723B2 System for displaying information to a user 有权
公开(公告)号：US11170723B2
公开(公告)日：2021-11-09
申请号：US16976868
申请日：2018-03-09
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
发明人： Ivan C. Baines , Moritz Kreysing
IPC分类号： G09G3/34 , G02B27/01 , G09G3/00
摘要： The invention relates to a system for displaying information to a user, comprising: an emission device (12, 13) arranged to emit light so as to display information to a user (18), the emission device (12, 13) being adapted to emit the light in a pulsed manner so that the intensity of the light varies between a high value and a low value, a selective viewing device (16) comprising a panel, the panel being adapted so that the user can view the light (11′) which is emitted by the emission device through that panel so as to visually perceive the information being displayed, the panel having a variable transparency which can be varied between a state of high transparency and a state of low transparency, the system being adapted to synchronize the emission device (12, 13) and the selective viewing device (16) so that the states of the emission device emitting light at a high-intensity value and the states of the panel of the selective viewing device of high transparency overlap in time, the emission device being adapted so that the light is emitted in a pulsed manner with a duty cycle of less than or equal to 1/10, wherein the panel of the selective viewing device is adapted to operate at essentially the same duty cycle.

6. 发明申请

US20200379235A1 Apparatus and Method for Simultaneous Imaging and Execution of Contact-Free Directed Hydrodynamic Flow 审中-公开
公开(公告)号：US20200379235A1
公开(公告)日：2020-12-03
申请号：US16766456
申请日：2018-11-23
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V.
发明人： Moritz Kreysing , Anatol Fritsch , Matthaeus Mittasch
IPC分类号： G02B21/36 , G02B21/02 , G02B21/00 , G02B21/08 , G02B21/28 , G02B21/30 , B01L3/00
摘要： The present invention relates to an apparatus for simultaneous imaging and execution of contact-free directed hydrodynamic flow in a specimen with at least one light source, in particular a laser, adapted to dynamically heat the interior and/or a surface of the specimen, a microscope with an objective adapted to image at least a part of the specimen and to guide, in particular focus, a light beam of the light source, in particular a laser beam, into and/or onto the specimen to heat at least one specified location of the specimen, means for manipulating the specified location, and a sample chamber for the specimen that is accessible for imaging radiation and the light beam to allow simultaneous imaging and manipulation of the sample via the objective. Furthermore the present invention is directed to a method for simultaneous imaging and executing contact-free directed hydrodynamic flow in a specimen wherein, at least one light source, in particular a laser, dynamically heats the interior and/or a surface of the specimen via a light beam, in particular via a laser beam, the beam of the at least one light source is directed to the specimen through an objective of a microscope, the light beam is variably guided, in particular focused, to specified locations of the specimen inducing a hydrodynamic flow in the specimen, and imaging the specimen via the same objective as used for introduction of the light beam.

7. 发明授权

US12136367B2 System for displaying information to a user 有权
公开(公告)号：US12136367B2
公开(公告)日：2024-11-05
申请号：US17640708
申请日：2019-09-06
申请人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
发明人： Moritz Kreysing
IPC分类号： G09G3/00 , G02B30/24 , H02S10/20 , H02S10/40 , H02S30/20
CPC分类号： G09G3/002 , G02B30/24 , H02S10/20 , H02S10/40 , H02S30/20 , G09G2310/08 , G09G2320/0233 , G09G2320/0247 , G09G2330/023
摘要： The invention relates to a system for displaying information, comprising: an emission device arranged to emit light so as to display information to a user, the emission device being adapted to emit the light in a pulsed manner so that the intensity of the light varies between a high value and a low value, a selective viewing device comprising a panel, the panel being adapted so that the user can view the light which is emitted by the emission device through that panel so as to visually perceive the information being displayed, the panel having a variable transparency which can be varied between a state of high transparency and a state of low transparency, the system being adapted to synchronize the emission device and the selective viewing device so that the states of the emission device emitting light at a high-intensity value and the states of the panel of the selective viewing device of high transparency overlap in time, the system further comprising a photoelectric conversion means arranged to convert ambient light into electric energy so as to feed the electric energy into the system.

8. 发明授权

US11694640B2 System for displaying information to a user 有权
公开(公告)号：US11694640B2
公开(公告)日：2023-07-04
申请号：US17506750
申请日：2021-10-21
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
发明人： Ivan C. Baines , Moritz Kreysing
IPC分类号： G09G3/34 , G02B27/01 , G09G3/00 , G02B27/00 , H04N13/00
CPC分类号： G09G3/3406 , G02B27/0172 , G09G3/002 , G02B2027/0118 , G02B2027/0178 , G09G2320/0247 , G09G2320/064 , G09G2320/066 , G09G2330/021 , G09G2360/144
摘要： The invention relates to a system for displaying information to a user, comprising:

an emission device arranged to emit light so as to display information to a user, the emission device being adapted to emit the light in a pulsed manner so that the intensity of the light varies between a high value and a low value,
a selective viewing device comprising a panel, the panel being adapted so that the user can view the light which is emitted by the emission device through that panel so as to visually perceive the information being displayed, the panel having a variable transparency which can be varied between a state of high transparency and a state of low transparency,
the system being adapted to synchronize the emission device and the selective viewing device so that the states of the emission device emitting light at a high-intensity value and the states of the panel of the selective viewing device of high transparency overlap in time,
the emission device being adapted so that the light is emitted in a pulsed manner with a duty cycle of less than or equal to 1/10, wherein the panel of the selective viewing device is adapted to operate at essentially the same duty cycle.

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