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    • 1. 发明申请
    • APPARATUS AND METHODS FOR CONTROLLING AND AUTOMATING FLUID INFUSION ACTIVITIES
    • 控制和自动化流体输注活动的装置和方法
    • US20070060874A1
    • 2007-03-15
    • US11530576
    • 2006-09-11
    • Matthew NesbittRoss KroghRandy StephensPaul NiklewskiMichael BoehmSatyajeet Parakh
    • Matthew NesbittRoss KroghRandy StephensPaul NiklewskiMichael BoehmSatyajeet Parakh
    • A61M5/14
    • A61M5/14228A61M5/14A61M5/1408A61M5/142A61M5/168A61M5/16813A61M5/16831A61M5/1723A61M39/28
    • The present invention provides apparatuses and methods to safely and economically deliver infusion fluid to a patient during a medical procedure. The infusion fluid may be a sedative, analgesic, amnestic or other pharmaceutical agent (drug) for alleviating a patient's pain and anxiety before, during and/or after a medical or surgical procedure. In general the apparatus comprises a microprocessor-based controller that receives inputs from a plurality of physiological monitors attached to a patient. The system controller processes the data from the physiological monitors and based upon a fluid infusion algorithm delivers infusion fluid to a patient. The physiological monitors monitor the patient throughout the course of the procedure and depending upon the health of the patient, drug delivery may be adjusted to optimize the procedure while ensuring the patient's health is maintained. Functionality detectors such as an occlusion sensor, air-in-line sensor and a fluid detection sensor alert a clinician to such hazards as a pressure build up in the infusion line, air-bubbles in the infusion line, and the absence of fluid in the infusion line.
    • 本发明提供了在医疗过程中安全和经济地将输注液输送到患者的装置和方法。 输液可以是用于在医疗或外科手术之前,期间和/或之后缓解患者的疼痛和焦虑的镇静剂,止痛剂,遗忘剂或其他药剂(药物)。 通常,该装置包括基于微处理器的控制器,其接收来自附接到患者的多个生理监视器的输入。 系统控制器处理来自生理监视器的数据,并且基于流体输注算法将输注流体输送给患者。 生理监护仪在整个程序过程中监测患者,并且根据患者的健康状况,可以调整药物递送以优化手术,同时确保维持患者的健康。 诸如遮挡传感器,一体式传感器和流体检测传感器的功能检测器警告临床医生诸如在输注管线中积聚的压力,输注管线中的气泡和在输液管线中不存在流体的危险 输液线。
    • 5. 发明授权
    • Device for automatic chemical analysis
    • 自动化学分析装置
    • US5693292A
    • 1997-12-02
    • US477813
    • 1995-06-07
    • Alfredo ChoperenaRoss KroghVenkatesh PrasadGershon Giter
    • Alfredo ChoperenaRoss KroghVenkatesh PrasadGershon Giter
    • G01N35/00G01N35/02G01N35/04G01N35/10
    • G01N35/0092G01N35/021G01N2035/0467G01N2035/1025G01N35/0098G01N35/1004Y10T436/11Y10T436/113332Y10T436/114165Y10T436/114998Y10T436/115831Y10T436/2575
    • This invention provides an automated chemical analyzer with improved processing flexibility and ease. In one embodiment of this invention, the analyzer includes an incubation station, a wash station and a read station. The incubation station includes an elongated, movable track to carry reaction vessels along an incubation path, the wash station includes a movable track to carry vessels along a wash-cycle path, and the read station is adapted to move vessels along a read path. A first transfer station is positioned adjacent a first end of the wash-cycle path to transfer vessels from the incubation path to the wash-cycle path and a second transfer station is positioned adjacent a second end of the wash-cycle path and a first end of the read path for selectively transferring a vessel from the wash-cycle path to either the incubation path or the read path. The system also includes an analyzer controller having scheduling means for allocating assay resources to one of the reaction vessels and transfer control means for controlling the transfer of reaction vessels from one assay resource station to another according to a chronology selected from a plurality of different predetermined chronologies.
    • 本发明提供一种自动化学分析仪,其具有改善的加工灵活性和容易性。 在本发明的一个实施例中,分析仪包括孵化站,洗涤站和读站。 孵化站包括细长的活动轨道,沿着孵化路径携带反应容器,洗涤站包括沿着洗涤循环路径运送血管的活动轨迹,并且读取站适于沿着读取路径移动容器。 第一转运站位于洗涤循环路径的第一端附近,以将容器从孵化路径转移到洗涤循环路径,并且第二转运站位于洗涤循环路径的第二端附近,第一端 用于选择性地将容器从洗涤循环路径转移到培养路径或读取路径的读取路径。 该系统还包括分析器控制器,其具有调度装置,用于将测定资源分配到反应容器之一和转移控制装置,用于控制反应容器从一个测定资源站到另一个测定资源站的转移,根据从多个不同的预定年表选择的年表 。
    • 6. 发明授权
    • Device for automatic chemical analysis
    • 自动化学分析装置
    • US5380487A
    • 1995-01-10
    • US878956
    • 1992-05-05
    • Alfredo ChoperenaRoss KroghVenkatesh PrasadGershon Giter
    • Alfredo ChoperenaRoss KroghVenkatesh PrasadGershon Giter
    • G01N35/00G01N35/02G01N35/04G01N35/10G01N33/48B65G43/08
    • G01N35/0092G01N35/021G01N2035/0467G01N2035/1025G01N35/0098G01N35/1004Y10T436/11Y10T436/113332Y10T436/114165Y10T436/114998Y10T436/115831Y10T436/2575
    • The present invention provides an analyzer which permits clinical analysis of samples for multiple analytes with a variety of assay protocols in a multiple chronology sequence while operating on a predetermined fizzed length cycle method of timing control. In this analyzer, assay resources (e.g. an incubator belt, a wash station, and a signal detection apparatus) are assigned fixed operating sequences which begin and end within a time cycle of fixed duration. Samples may be transferred directly from one assay resource to another without unnecessarily occupying any unused resources. The invention also contemplates a method of analyzing samples consistent with use of this analyzer. In this method, different samples having different assay protocols may be entered into the analyzer. The assay resource requirements of the first sample are determined and "time slots" of the assay resources are allocated to that sample. The second sample, which may have a different assay protocol from the first, is entered and its assay resource requirements are determined, and available time slots of the assay resources are assigned to the second assay. By assigning "time slots" of the resources to the samples, flexibility and throughput of the system may be maximized without unduly complicating the scheduling logic and control.
    • 本发明提供了一种分析仪,其允许以多个时间序列中的多种测定方案临时分析多种分析物的样品,同时以预定的定时长度循环方法进行定时控制。 在该分析仪中,分析资源(例如,孵化器带,洗涤站和信号检测装置)被分配固定的操作序列,其在固定持续时间的时间周期内开始和结束。 样品可以直接从一个测定资源转移到另一个测定资源,而不必占用任何未使用的资源。 本发明还考虑了使用该分析仪分析样品的方法。 在该方法中,可以将不同的具有不同测定方案的样品输入分析仪。 确定第一个样品的测定资源需求,并将分析资源的“时隙”分配给该样品。 输入第二个样品,其可以具有与第一个不同的测定方案,并确定其测定资源需求,并将测定资源的可用时隙分配给第二测定。 通过将资源的“时隙”分配给样本,可以最大化系统的灵活性和吞吐量,而不会使调度逻辑和控制过度复杂化。
    • 7. 发明申请
    • INTRAVENOUS PUMPING AIR MANAGEMENT SYSTEMS AND METHODS
    • 空调泵送空气管理系统及方法
    • US20120172800A1
    • 2012-07-05
    • US12981152
    • 2010-12-29
    • Thomas DudarRoss KroghJames MartucciShmuel Sternberg
    • Thomas DudarRoss KroghJames MartucciShmuel Sternberg
    • A61M5/36A61M5/38
    • A61M5/172A61M5/36A61M5/365A61M5/38A61M5/385A61M2205/60
    • An intravenous (“IV”) liquid delivery system includes: an IV pump tubing set; a shuttle pump or membrane pump actuator operable with the IV pump tubing set; upstream and downstream valve actuators operable with the IV pump tubing set; the IV pump tubing set including an air removal device; an air detector configured to sense air in the IV pump tubing set; a control unit configured and arranged to (i) open the upstream valve actuator and close the downstream valve actuator to allow the pump actuator to draw liquid into a pump actuation portion of the IV pump tubing set, and (ii) close the upstream valve actuator and open the downstream valve actuator to allow the pump actuator to push liquid out of the pump actuation portion, the system configured to attempt to remove the air via the air removal device while operating the upstream and downstream valve actuators according to (i) and (ii).
    • 静脉内(“IV”)液体输送系统包括:IV泵管组; 一个穿梭泵或膜泵驱动器,可与IV泵管组一起操作; 上游和下游阀致动器可与IV泵管组一起操作; 所述IV泵管组包括排气装置; 空气检测器,被配置为感测IV泵管组中的空气; 控制单元,其配置和布置成(i)打开上游阀致动器并关闭下游阀致动器以允许泵致动器将液体引入IV泵管组的泵致动部分,以及(ii)关闭上游阀致动器 并且打开下游阀致动器以允许泵致动器将液体推出泵致动部分,该系统构造成在根据(i)和(i)和(i))操作上游和下游阀致动器期间尝试经由除气装置去除空气, ii)。
    • 10. 发明授权
    • Method and device for automatic chemical analysis
    • 自动化学分析方法和装置
    • US5882596A
    • 1999-03-16
    • US797182
    • 1997-02-10
    • David BreeserAlan WirbiskyRoss Krogh
    • David BreeserAlan WirbiskyRoss Krogh
    • G01N35/04
    • G01N35/04G01N2035/0406G01N2035/0467Y10T436/11Y10T436/113332Y10T436/114165
    • The present invention provides a vessel shuttle which can be used, for example, for moving reaction vessels to or from an assay resource station in an automated chemical analyzer. The vessel shuttle has a plurality of movable plates including first and second vessel carrying plates adapted to move cooperatively with respect to one another to advance a vessel stepwise along a linear path without net motion of the first and second vessel carrying plates as the vessel is advanced one step. In a preferred embodiment, the first and second vessel carrying plates each comprise a plurality of fingers defining recesses for receiving vessels and the first vessel carrying plate is adapted to move in a direction substantially perpendicular to the vessels' linear path and the second vessel carrying plate is adapted to move rectilinearly both generally parallel to and generally perpendicular to that linear path. The present invention may also include a waste chute for disposing of spent reaction vessels, the waste chute having a novel gate design. In accordance with this embodiment, the vessel shuttle can move a new vessel to a position for access by a pipettor or the like, transport a reaction vessel from the vessel shuttle to an adjacent assay resource station, and transport a reaction vessel from that assay resource station to the waste chute in one motion of the vessel shuttle.
    • 本发明提供了可用于例如用于将自动化学分析仪中的测定资源站移动到或来自测定资源站的反应容器的血管梭。 船舶梭具有多个可移动板,包括第一和第二船只承载板,其适于彼此协作地移动,以在船只前进时沿着线性路径逐步推进船舶,而没有第一和第二船只承载板的网络运动 一步。 在优选实施例中,第一和第二容器承载板各自包括限定用于容纳容器的凹部的多个指状件,并且第一容器承载板适于沿基本上垂直于容器的线性路径的方向移动,并且第二容器承载板 适于直线移动,大致平行于并且大致垂直于该线性路径。 本发明还可以包括用于处理用过的反应容器的废料槽,废物槽具有新的浇口设计。 根据本实施例,血管穿梭器可以将新血管移动到通过移液器等进入的位置,将反应容器从血管穿梭器运输到相邻的测定资源站,并从该测定资源输送反应容器 站到垃圾槽一次运动的船只穿梭。