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1. 发明申请

US20100261205A1 MICROCHIPS, KITS, AND METHODS FOR IMMUNOASSAYS 有权
标题翻译： MICROCHIPS，KITS和免疫学方法
公开(公告)号：US20100261205A1
公开(公告)日：2010-10-14
申请号：US12159371
申请日：2006-12-25
申请人： Masaya Kakuta , Manabu Tokeshi , Hitoshi Izumida , Takahide Takadera , Kenji Miyagawa
发明人： Masaya Kakuta , Manabu Tokeshi , Hitoshi Izumida , Takahide Takadera , Kenji Miyagawa
IPC分类号： G01N33/53
CPC分类号： G01N33/54366 , G01N33/54313
摘要： An objective of the present invention is to provide immunoassay microchips in which microstructures of beads having a sufficient reaction area were constructed within microchannels while suppressing flow path resistance, and to provide simple and highly-sensitive immunoassay methods for microsamples. The objective was achieved by immunoassay microchips comprising microchannels with microstructures arranged in at least a portion of the microchannels, the microstructures retaining microbeads uniformly dispersed in photo-cured hydrophilic resins, and the microbeads having a primary antibody immobilized on their surfaces, and by immunoassay methods using the microchips.
摘要翻译：本发明的目的是提供免疫测定微芯片，其中在微通道内构建具有足够反应面积的珠的微结构，同时抑制流路阻力，并提供用于微样品的简单和高灵敏度的免疫测定方法。目的是通过免疫测定微芯片实现，该微芯片包括微通道的微通道，该微通道布置在微通道的至少一部分上，保持微珠均匀分散在光固化的亲水性树脂中的微观结构，以及具有固定在其表面上的一抗体的微珠，以及通过免疫测定方法使用微芯片。

2. 发明授权

US08802449B2 Microchips, kits, and methods for immunoassays 有权
标题翻译：微芯片，试剂盒和免疫测定方法
公开(公告)号：US08802449B2
公开(公告)日：2014-08-12
申请号：US12159371
申请日：2006-12-25
申请人： Masaya Kakuta , Manabu Tokeshi , Hitoshi Izumida , Takahide Takadera , Kenji Miyagawa
发明人： Masaya Kakuta , Manabu Tokeshi , Hitoshi Izumida , Takahide Takadera , Kenji Miyagawa
IPC分类号： G01N33/544
CPC分类号： G01N33/54366 , G01N33/54313
摘要： An objective of the present invention is to provide immunoassay microchips in which microstructures of beads having a sufficient reaction area were constructed within microchannels while suppressing flow path resistance, and to provide simple and highly-sensitive immunoassay methods for microsamples. The objective was achieved by immunoassay microchips comprising microchannels with microstructures arranged in at least a portion of the microchannels, the microstructures retaining microbeads uniformly dispersed in photo-cured hydrophilic resins, and the microbeads having a primary antibody immobilized on their surfaces, and by immunoassay methods using the microchips.
摘要翻译：本发明的目的是提供免疫测定微芯片，其中在微通道内构建具有足够反应面积的珠的微结构，同时抑制流路阻力，并提供用于微样品的简单和高灵敏度的免疫测定方法。目的是通过免疫测定微芯片实现，该微芯片包括微通道的微通道，该微通道布置在微通道的至少一部分上，保持微珠均匀分散在光固化的亲水性树脂中的微观结构，以及具有固定在其表面上的一抗体的微珠，以及通过免疫测定方法使用微芯片。

3. 发明授权

US5130834A Liquid crystal display including a dye complementary to the liquid crystal's bright state color 失效
标题翻译：液晶显示器包括与液晶的亮状态互补的染料
公开(公告)号：US5130834A
公开(公告)日：1992-07-14
申请号：US263458
申请日：1988-10-27
申请人： Mitsuru Kano , Kenji Miyagawa , Masahiko Yamaguchi , Eiji Imaizumi
发明人： Mitsuru Kano , Kenji Miyagawa , Masahiko Yamaguchi , Eiji Imaizumi
IPC分类号： G02F1/133 , C09K19/00 , G02F1/137 , G02F1/139
CPC分类号： G02F1/1397 , G02F1/13725
摘要： A liquid crystal display includes a pair of substrates and a liquid crystal composition sealed between the substrates. The liquid crystal composition has a twist angle set within a range of 180-300 degrees and a retardation set within a range of 0.45-0.7 .mu.m wherein when an electric field is applied, the liquid crystal display is in a dark state, while when the electrid field is not applied, the liquid crystal display is in a bright state. A dichromatic coloring matter is contained in the liquid crystal composition, and it has a hue complementary to that of an image color of the liquid-crystal display in the bright state.
摘要翻译：液晶显示器包括一对基板和密封在基板之间的液晶组合物。液晶组合物的扭转角设定在180〜300度的范围内，相位差设定在0.45〜0.7μm的范围内，当施加电场时，液晶显示器处于黑暗状态，而当不施加电场，液晶显示器处于亮状态。液晶组合物中含有二色性色素，并且在亮状态下具有与液晶显示器的图像颜色互补的色调。

4. 发明授权

US06855746B2 Process for the production of molded particles for enzyme- or microbial cell-immobilization 失效
标题翻译：用于生产用于酶或微生物细胞固定的模制颗粒的方法
公开(公告)号：US06855746B2
公开(公告)日：2005-02-15
申请号：US10293500
申请日：2002-11-14
申请人： Junya Yoshitake , Kenji Miyagawa , Kenji Seko
发明人： Junya Yoshitake , Kenji Miyagawa , Kenji Seko
IPC分类号： C08G18/12 , C08G18/32 , C08G18/48 , C08G18/67 , C08G18/81 , C12N11/08 , C12N11/10 , C08F2/46
CPC分类号： C08G18/12 , C08G18/4833 , C08G18/672 , C08G18/675 , C08G18/8116 , C08G2220/00 , C12N11/08 , C12N11/10 , Y10T428/2982
摘要： This invention provides a process for the production of molded particles for enzyme- or microbial cell-immobilization which is characterized in that:an aqueous liquid composition which comprises: (A) an unsaturated group-containing urethane resin which is obtained by making a compound (a) having one hydroxyl group and one epoxy group in a molecule react with a compound (b) having one carboxyl group and one ethylenically unsaturated group in a molecule, and further making thus obtained unsaturated group-containing diol (c) react with polyisocyanate compound (d); (B) a polymerization initiator; and (C) water-soluble macromolecular polysaccharides which are capable of gelation by contact with metal ion; is gelatinized, in an aqueous medium which contains metal ion, to be particulate gel, which is then subjected to photopolymerization and/or thermopolymerization by which to cause the crosslinking reaction of ethylenically unsaturated group in said particulate gel.
摘要翻译：本发明提供一种生产用于酶或微生物细胞固定的模塑颗粒的方法，其特征在于：一种含水液体组合物，其包含：（A）含不饱和基团的聚氨酯树脂，其通过制备化合物 a）在分子中具有一个羟基和一个环氧基与分子中具有一个羧基和一个烯键式不饱和基团的化合物（b）反应，并且进一步制得如此获得的不饱和基团的二醇（c）与多异氰酸酯化合物（d）;（B）聚合引发剂; 和（C）能够通过与金属离子接触而凝胶化的水溶性大分子多糖在含有金属离子的水性介质中凝胶化成为颗粒状凝胶，然后将其进行光聚合和/或热聚合，引起所述颗粒状凝胶中烯属不饱和基团的交联反应。

5. 发明授权

US06706778B2 Process for the production of molded particles for microbial cell-immobilization 有权
标题翻译：用于生产用于微生物细胞固定的模制颗粒的方法
公开(公告)号：US06706778B2
公开(公告)日：2004-03-16
申请号：US10059309
申请日：2002-01-31
申请人： Junya Yoshitake , Kenji Miyagawa , Kenji Seko
发明人： Junya Yoshitake , Kenji Miyagawa , Kenji Seko
IPC分类号： C08F246
CPC分类号： C08G18/0814 , C08F299/06 , C08G18/672 , C08G2210/00 , C08G18/48
摘要： This invention provides a process for the production of molded particles for microbial cell-immobilization which is characterized in that: an aqueous liquid composition which comprises: (a) an ethylenically unsaturated group-containing urethane resin which is obtained by making a tertiary amino group-containing diol react with a polyisocyanate compound, and by further introducing an ethylenically unsaturated group; (b) a polymerization initiator; and (c) water-soluble macromolecular polysaccharides; is gelatinized, in an aqueous medium which contains metal ion, to be particulate gel which is then subjected to photopolymerization and/or thermopolymerization by which to cause the crosslinking reaction of ethylenically unsaturated group in said particulate gel.
摘要翻译：本发明提供一种生产用于微生物细胞固定的模制颗粒的方法，其特征在于：一种含水液体组合物，其包含：（a）含烯属不饱和基团的聚氨酯树脂，其通过制备叔氨基 - 含二醇与多异氰酸酯化合物反应，并进一步引入烯属不饱和基团;（b）聚合引发剂; 和（c）水溶性大分子多糖;在含有金属离子的水性介质中胶凝成为颗粒状凝胶，然后将其进行光聚合和/或热聚合，通过该聚合和/或热聚合使烯属不饱和基团在所述颗粒中的交联反应凝胶。

6. 发明授权

US4930877A Liquid crystal display 失效
标题翻译：液晶显示器
公开(公告)号：US4930877A
公开(公告)日：1990-06-05
申请号：US263468
申请日：1988-10-27
申请人： Mitsuru Kano , Kenji Miyagawa , Masahiko Yamaguchi , Eiji Imaizumi
发明人： Mitsuru Kano , Kenji Miyagawa , Masahiko Yamaguchi , Eiji Imaizumi
IPC分类号： G02F1/133 , C09K19/00 , G02F1/1335 , G02F1/139
CPC分类号： G02F1/1397 , G02F1/133509
摘要： A liquid crystal display includes a pair of substrates and a liquid crystal composition sealed between the substrates. The liquid crystal composition has a twist angle set within a range of 180-300 degrees and a retardation set within a range of 0.45-0.7, wherein when an electric field is applied, the liquid crystal display is in a dark state, while when the electric field is not applied, the liquid crystal display is in a bright state. A filter is laminated on the outside of the substrates, and it has a hue complementary to that of an image color of the liquid crystal display in the bright state.
摘要翻译：液晶显示器包括一对基板和密封在基板之间的液晶组合物。液晶组合物的扭转角设定在180〜300度的范围内，相位差设定在0.45〜0.7的范围内，其中当施加电场时，液晶显示器处于黑暗状态，而当不施加电场，液晶显示器处于亮状态。在基板的外侧层叠有过滤器，并且在亮状态下具有与液晶显示器的图像颜色互补的色调。

7. 发明授权

US06780561B2 Polybenzoxazole precursor and coating composition using the same 失效
标题翻译：聚苯并恶唑前体和使用其的涂料组合物
公开(公告)号：US06780561B2
公开(公告)日：2004-08-24
申请号：US10303988
申请日：2002-11-26
申请人： Mitsuru Ueda , Kazuya Ebara , Kenji Miyagawa , Kazuo Yamanaka , Yoichi Yonehara
发明人： Mitsuru Ueda , Kazuya Ebara , Kenji Miyagawa , Kazuo Yamanaka , Yoichi Yonehara
IPC分类号： G03F7023
CPC分类号： G03F7/0233 , C08G73/22 , H01L23/49894 , H01L23/5329 , H01L2924/0002 , H01L2924/00
摘要： Provided is a polybenzoxazole precursor having a high purity which does not contain ionic by-products. The above polybenzoxazole precursor comprises a repetitive unit represented by Formula (1): wherein A1 represents a tetravalent aromatic group; N and OH which are bonded to A1 are paired, and the respective pairs of N and OH are bonded to carbons which are adjacent to each other on the same aromatic ring; A2 represents a divalent organic group; and n represents a number of 2 to 300.
摘要翻译：本发明提供高纯度的不含离子副产物的聚苯并恶唑前体。上述聚苯并恶唑前体包含由式（1）表示的重复单元：其中A1表示四价芳族基团; 与A1键合的N和OH成对，并且各对的N和OH与相同芳环上彼此相邻的碳键合; A2表示二价有机基团; n表示2〜300的数。

8. 发明授权

US6114092A Photosensitive resin compositions for photoresist 失效
标题翻译：用于光致抗蚀剂的光敏树脂组合物
公开(公告)号：US6114092A
公开(公告)日：2000-09-05
申请号：US161717
申请日：1998-09-29
申请人： Kenji Miyagawa , Kenji Seko
发明人： Kenji Miyagawa , Kenji Seko
IPC分类号： G03F7/031 , G03F7/033 , G03F7/038
CPC分类号： G03F7/033 , G03F7/031 , G03F7/0388 , Y10S430/12 , Y10S430/121 , Y10S430/123 , Y10S430/127 , Y10S430/148
摘要： A photosensitive resin composition for photoresist which is highly sensitive and can directly form an image using a laser is disclosed. Said composition comprises (A) an unsaturated resin having carboxyl group(s) which is obtained by firstly reacting 0.8 to 1.3 moles of an ethylenic unsaturated monocarboxylic acid with 1 mole of an epoxy group of a homopolymer or copolymer of ethylenic unsaturated monomer having an epoxy group to obtain an unsaturated resin which is then reacted with a dibasic acid anhydride, (B) ethylenic unsaturated compound without epoxy group, and (C) photopolymerization initiator.
摘要翻译：公开了一种高灵敏度并且可以使用激光直接形成图像的光致抗蚀剂用感光性树脂组合物。所述组合物包含（A）具有羧基的不饱和树脂，其通过首先使0.8至1.3摩尔的烯属不饱和单羧酸与1摩尔环氧基的具有环氧基的烯键式不饱和单体的均聚物或共聚物得到不饱和树脂，然后与二元酸酐反应，（B）不含环氧基的烯属不饱和化合物，和（C）光聚合引发剂。

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