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1. 发明授权

US4624735A Constituent members of a semiconductor element-manufacturing apparatus and a reaction furnace for making said constituent members 失效
标题翻译：半导体元件制造装置的构成部件和用于制造所述构成部件的反应炉
公开(公告)号：US4624735A
公开(公告)日：1986-11-25
申请号：US701641
申请日：1985-02-11
申请人： Masao Koyama , Syuitu Matuo , Chiaki Nakayama , Katsumi Hoshina
发明人： Masao Koyama , Syuitu Matuo , Chiaki Nakayama , Katsumi Hoshina
IPC分类号： C04B35/52 , C04B41/50 , C04B41/87 , C30B15/10 , C30B25/08 , C30B25/12 , C30B35/00 , H01L21/205 , H01L21/22
CPC分类号： C04B41/009 , C04B35/52 , C04B41/5059 , C04B41/87 , C30B15/10 , C30B25/08 , C30B25/12 , C30B35/00 , H01L21/02376 , H01L21/02529 , H01L21/0262 , Y10S117/90 , Y10S438/931 , Y10T117/1024 , Y10T428/26 , Y10T428/263
摘要： The constituent members of a semiconductor element-manufacturing apparatus which are formed by depositing a silicon carbide layer on a carbon substrate, and wherein a peak X-ray diffraction on the (200) plane of the silicon carbide layer has a half value width of 0.35.degree. or less as measured by the C.sub.u --K.sub..alpha. ray used in the X-ray diffraction analysis.
摘要翻译：通过在碳衬底上沉积碳化硅层而形成的半导体元件制造装置的构成部件，其中碳化硅层的（200）面上的峰值X射线衍射的半值宽度为0.35 DEG或以下，通过X射线衍射分析中使用的Cu-Kα射线测量。

2. 发明授权

US4424193A Constituent members of a semiconductor element-manufacturing apparatus and a reaction furnace for making said constituent members 失效
标题翻译：半导体元件制造装置的构成部件和用于制造所述构成部件的反应炉
公开(公告)号：US4424193A
公开(公告)日：1984-01-03
申请号：US162943
申请日：1980-06-25
申请人： Masao Koyama , Syuitu Matuo , Chiaki Nakayama , Katsumi Hoshina
发明人： Masao Koyama , Syuitu Matuo , Chiaki Nakayama , Katsumi Hoshina
IPC分类号： C04B35/52 , C04B41/50 , C04B41/87 , C30B15/10 , C30B25/08 , C30B25/12 , C30B35/00 , H01L21/205 , H01L21/22 , C30B25/10
CPC分类号： C04B41/009 , C04B35/52 , C04B41/5059 , C04B41/87 , C30B15/10 , C30B25/08 , C30B25/12 , C30B35/00 , H01L21/02376 , H01L21/02529 , H01L21/0262 , Y10S117/90 , Y10S438/931 , Y10T117/1024 , Y10T428/26 , Y10T428/263
摘要： The constituent members of a semiconductor element-manufacturing apparatus which are formed by depositing a silicon carbide layer on a carbon substrate, and wherein a peak X-ray diffraction on the (200) plane of the silicon carbide layer has a half value width of 0.35.degree. or less as measured by the C.sub.u -K.sub..alpha. ray used in the X-ray diffraction analysis.
摘要翻译：通过在碳衬底上沉积碳化硅层而形成的半导体元件制造装置的构成部件，其中碳化硅层的（200）面上的峰值X射线衍射的半值宽度为0.35 DEG或以下，通过X射线衍射分析中使用的Cu-Kα射线测量。

3. 发明授权

US06498251B1 Tetrahydrobenzindole derivatives 失效
标题翻译：四氢苯并吲哚衍生物
公开(公告)号：US06498251B1
公开(公告)日：2002-12-24
申请号：US09582416
申请日：2001-03-08
申请人： Chika Kikuchi , Takashi Ando , Kazuyuki Fuji , Masayo Okuno , Eriko Morita , Masako Imai , Osamu Ushiroda , Masao Koyama , Toyokazu Hiranuma
发明人： Chika Kikuchi , Takashi Ando , Kazuyuki Fuji , Masayo Okuno , Eriko Morita , Masako Imai , Osamu Ushiroda , Masao Koyama , Toyokazu Hiranuma
IPC分类号： C07D20990
CPC分类号： C07D401/06 , C07D209/92 , C07D405/12 , C07D471/04 , C07D487/04
摘要： Compounds containing tetrahydrobenzindole which bind to serotonin receptor and are useful in treatment or prevention of disease induced by abnormality of central peripheral serotonin controlling functions.
摘要翻译：含有与5-羟色胺受体结合的四氢苯并吲哚的化合物，可用于治疗或预防由中枢外周血清素控制功能异常引起的疾病。

4. 发明授权

US06407112B1 Optically active tetrahydrobenzindole derivative 失效
标题翻译：光活性四氢苯并吲哚衍生物
公开(公告)号：US06407112B1
公开(公告)日：2002-06-18
申请号：US09673833
申请日：2000-10-23
申请人： Masao Koyama , Osamu Ushiroda , Chika Kikuchi , Takashi Ando , Eriko Morita , Masayo Okuno , Toyokazu Hiranuma
发明人： Masao Koyama , Osamu Ushiroda , Chika Kikuchi , Takashi Ando , Eriko Morita , Masayo Okuno , Toyokazu Hiranuma
IPC分类号： C07D20992
CPC分类号： C07D471/04 , C07D209/92 , C07D491/04 , C07D495/04
摘要： Optically active tetrahydrobenzindole type compounds having affinity for a 5-HT receptor, useful for prevention and treatment of mental diseases. A species compound is (S)-2a-4-(4-(2-methoxyphenyl)piperazinyl)butyl)-2a,3,4,5,-tetrahydro 1 H-benz[cd]indol-2-one.
摘要翻译：对5-HT受体具有亲和力的光学活性四氢苯并吲哚型化合物，可用于预防和治疗精神疾病。化合物为（S）-2a-4-（4-（2-甲氧基苯基）哌嗪基）丁基）-2a，3,4,5， - 四氢-1H-苯并[cd]吲哚-2-酮。

5. 发明授权

US4994578A Certain anti-tumor duocarmycin antibiotics from streptomyces 失效
标题翻译：某些来自链霉菌的抗肿瘤双卡霉素抗生素
公开(公告)号：US4994578A
公开(公告)日：1991-02-19
申请号：US344738
申请日：1989-04-28
申请人： Kazunori Ohba , Hiroomi Watabe , Mieko Nagasawa , Shiro Sakakibara , Takashi Shomura , Masaji Sezaki , Shinichi Kondo , Masao Koyama , Tadashi Nakazawa , Haruo Yamamoto
发明人： Kazunori Ohba , Hiroomi Watabe , Mieko Nagasawa , Shiro Sakakibara , Takashi Shomura , Masaji Sezaki , Shinichi Kondo , Masao Koyama , Tadashi Nakazawa , Haruo Yamamoto
IPC分类号： C07D471/04 , C07D487/04 , C12P17/18
CPC分类号： C07D471/04 , C07D487/04 , C12P17/182
摘要： Novel substances exhibiting antimicrobial activity and antitumor activity, a process for producing them by cultivating a microorganism belonging to the genus Streptomyces and capable of producing them and derivatives of such substances.
摘要翻译：具有抗微生物活性和抗肿瘤活性的新型物质，通过培养属于链霉菌属的微生物并能够生产它们和这些物质的衍生物的方法。

6. 发明授权

US4758325A Ion selective electrode and flow type ion sensor using the same 失效
标题翻译：离子选择电极和流量型离子传感器使用相同
公开(公告)号：US4758325A
公开(公告)日：1988-07-19
申请号：US817798
申请日：1986-01-10
申请人： Ken-ichi Kanno , Tetsuya Gatayama , Masao Koyama
发明人： Ken-ichi Kanno , Tetsuya Gatayama , Masao Koyama
IPC分类号： G01N27/27 , G01N27/28 , G01N27/333 , G01N27/403 , G01N27/46
CPC分类号： G01N27/403 , G01N27/3335
摘要： There are disclosed an ion selective electrode comprising a polyvinyl chloride series resin plate having a through hole; conductive member disposed along the through hole; ion sensitive membrane of a polyvinyl chloride series resin membrane; and a lead wire connected to the conductive member, and the flow type ion sensor comprises a plurality of the ion selective electrodes mutually integrally associated with each other with the interposition of electrical insulating members so that through holes of the respective ion selective electrodes may define a flow passage for a liquid to be measured, and a flow type ion sensor using the same.The ion selective electrode and flow type ion sensor using the same of this invention allow the measurement in a smaller amount of the sample to be measured and are excellect in the adhesion of the ion sensitive membranes, therefore they have effects of a stable potential supply and a prolonged life time, and these industrial merits are highly great.
摘要翻译：公开了一种离子选择电极，其包括具有通孔的聚氯乙烯系树脂板; 导电构件沿着通孔设置; 聚氯乙烯系列树脂膜的离子敏感膜; 以及连接到导电构件的引线，并且流式离子传感器包括彼此一体地相互连接的多个离子选择电极，插入电绝缘构件，使得各个离子选择电极的通孔可以限定一个用于待测液体的流路，以及使用该液体的流动型离子传感器。使用本发明的离子选择电极和流动型离子传感器允许在较少量的待测量样品上进行测量，并且在离子敏感膜的粘附中具有优越性，因此它们具有稳定的电势供应和寿命延长，这些工业优点非常好。

7. 发明授权

US5053431A Derivatives of chrysophanol as topoisomerase II inhibitors 失效
标题翻译： chrysophanol的衍生物作为拓扑异构酶II抑制剂
公开(公告)号：US5053431A
公开(公告)日：1991-10-01
申请号：US544203
申请日：1990-06-26
申请人： Kyoichi A. Watanabe , Masao Koyama , Ting-Chao Chou
发明人： Kyoichi A. Watanabe , Masao Koyama , Ting-Chao Chou
IPC分类号： C07C50/34 , C07C225/24 , C07C271/12 , C07D295/116 , C07D521/00
CPC分类号： C07D295/116 , C07C225/24 , C07C271/12 , C07C50/34 , C07D231/12 , C07D233/56 , C07D249/08 , C07C2103/24
摘要： The present invention concerns compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen, a hydroxy group or a methoxy group;R.sup.2 is hydrogen or a methyl group;R.sup.3 is hydrogen or a methyl group;Y is a secondary amino group (NHalkyl) or a tertiary amino group (N(alkyl).sub.2); andZ is hydrogen or a halogen.The invention further provides a method of inhibiting topoisomerase II using a compound having the structure: ##STR2## wherein R.sup.1 is hydrogen, a hydroxy group or a methoxy group;R.sup.2 is hydrogen or a methyl group;R.sup.3 is hydrogen or a methyl group;Y is a halogen, secondary amino group (NHalkyl) or a tertiary amino group (N(alkyl).sub.2); andZ is hydrogen or a halogen.The invention further concerns pharmaceutical compositions which comprise the above-identified compound or the acid salts thereof, and the use of the compound or compositions for treating a malignancy in a subject.
摘要翻译：本发明涉及下式的化合物：其中R 1是氢，羟基或甲氧基; R2是氢或甲基; R3是氢或甲基; Y是仲氨基（NH烷基）或叔氨基（N（烷基）2）; Z是氢或卤素。本发明还提供了使用具有以下结构的化合物抑制拓扑异构酶II的方法：其中R1是氢，羟基或甲氧基; R2是氢或甲基; R3是氢或甲基; Y是卤素，仲氨基（NH烷基）或叔氨基（N（烷基）2）; Z是氢或卤素。本发明还涉及包含上述化合物或其酸式盐的药物组合物，以及该化合物或组合物用于治疗受试者恶性肿瘤的用途。

8. 发明授权

US3963712A 3-Halo-cephalosporins 失效
标题翻译： 3-卤代头孢菌素
公开(公告)号：US3963712A
公开(公告)日：1976-06-15
申请号：US350199
申请日：1973-04-11
申请人： Masao Koyama , Shigeo Seki
发明人： Masao Koyama , Shigeo Seki
IPC分类号： A61K31/545 , A61K31/546 , A61P31/04 , C07D501/10 , C07D501/14
CPC分类号： C07D501/10 , C07D501/14
摘要： A novel ester of 7-acylamido-3-methyl-cepham-4-carboxylic acid derivative and a process for the preparation thereof which comprises reacting penicillin sulfoxide ester with the metal halide, and a novel 7-acylamido-3-methyl-cepham-4-carboxylic acid derivative and a process for the preparation thereof which comprises reacting penicillin sulfoxide ester with the metal halide and decomposing the resultant in a reductive atmosphere.
摘要翻译：一种7-酰基氨基-3-甲基 - 头孢烯-4-羧酸衍生物的新型酯及其制备方法，其包括使青霉素亚砜酯与金属卤化物反应，以及新的7-酰基氨基-3-甲基 - 头孢烯-4-羧酸衍生物， 4-羧酸衍生物及其制备方法，其包括使青霉素亚砜酯与金属卤化物反应并在还原气氛中分解所得物。

9. 发明授权

US3939349A Method and device for classifying tires 失效
标题翻译：轮胎分级方法和装置
公开(公告)号：US3939349A
公开(公告)日：1976-02-17
申请号：US428014
申请日：1973-12-26
申请人： Masami Shimizu , Masao Koyama
发明人： Masami Shimizu , Masao Koyama
IPC分类号： C09J7/02 , G01N23/18 , G01T1/16
CPC分类号： G01N23/185 , G01N2223/627
摘要： During the process of manufacturing tires, vulcanized tires are classified by the utilization of radiations into the white tire having a white rubber compound layer, or a white ribbon, and the black tire having no such white ribbon, while those tires are classified according to the external dimensions such as an inside diameter. More specifically, a radiation source provided on the side of one wallside of a tire emits radiations to the tire at a predetermined angle of inclination, while a radiation detector provided on the side of the other wallside of the tire detects the intensity of radiations which have passed through the tire, whereby the classification of tires is carried out according to the comparison of two outputs which the radiation detector produces at two predetermined relative positions of the tire and the radiation source.
摘要翻译：在制造轮胎的过程中，通过利用具有白色橡胶化合物层或白色带状物的白色轮胎的辐射和不具有这种白色带的黑色轮胎来对硫化轮胎进行分类，而这些轮胎根据外部尺寸如内径。更具体地，设置在轮胎的一个侧壁侧的辐射源以预定的倾斜角度向轮胎发射辐射，而设置在轮胎另一侧面的辐射检测器检测到具有通过轮胎，从而根据辐射检测器在轮胎和辐射源的两个预定相对位置处产生的两个输出的比较来执行轮胎的分类。

10. 发明授权

US3935056A Apparatus for splicing parallelogrammatic pieces of rubber cloth without overlap 失效
标题翻译：用于拼接平行四边形橡胶布片而不重叠的装置
公开(公告)号：US3935056A
公开(公告)日：1976-01-27
申请号：US504418
申请日：1974-09-09
申请人： Masao Koyama , Noboru Okada , Masahiro Ogawa
发明人： Masao Koyama , Noboru Okada , Masahiro Ogawa
IPC分类号： G11B15/093 , B29C65/00 , B29D30/42 , G11B15/18 , G11B15/22 , G03D15/04
CPC分类号： B29D30/42 , B29C66/43 , B29C66/71 , B29C65/7891 , B29C66/1142 , B29D2030/427 , B29D2030/4406 , B29D2030/4418 , B29K2021/00 , Y10T156/1751
摘要： Rubber cloth splicing apparatus broadly comprising a forward vibrating conveyor, a butt-splicer, a backward vibrating conveyor, and a take-up conveyor. Each piece of rubber cloth is fed by the forward vibrating conveyor onto the rear table of the butt-splicer and is clamped in position thereon, whereas the precedingly spliced rubber cloth piece is fed backwardly by the backward vibrating conveyor onto the front table of the butt-splicer and is similarly clamped in position thereon. The two rubber cloth pieces are joined end to end without overlap as the rear table is forced into abutting contact with the front table. The take-up conveyor carries the spliced pieces of rubber cloth away from the butt-splicer via the backward vibrating conveyor by indexed movement.
摘要翻译：橡胶拼接装置广泛地包括前振动输送机，对接机，向后振动输送机和卷取输送机。每片橡胶布由正向振动输送机输送到对接机的后台上，并被夹紧在其上的位置，而前面拼接的橡胶布片由向后的振动输送机向后馈送到对接的前台上并且类似地夹在其上的位置。两个橡胶布片由于后台被迫与前台相接触而端对端连接而不重叠。卷取输送机通过向后振动输送机通过分度运动将拼接的橡胶布从对接机上分离。

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