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1. 发明授权

US5928297A Suspension control device of vehicle according to genetic algorithm 失效
标题翻译：根据遗传算法车辆悬架控制装置
公开(公告)号：US5928297A
公开(公告)日：1999-07-27
申请号：US792802
申请日：1997-02-03
申请人： Masahiro Murata , Tomomi Nakayama , Toshiyuki Kobayashi , Yasuhiko Mishio , Mitsuhiko Morita , Tomoko Tashiro
发明人： Masahiro Murata , Tomomi Nakayama , Toshiyuki Kobayashi , Yasuhiko Mishio , Mitsuhiko Morita , Tomoko Tashiro
IPC分类号： B60G17/015 , B60G17/016 , B60G17/0195 , B60G17/06
CPC分类号： B60G17/0195 , B60G17/016 , B60G17/06
摘要： A suspension control device for a vehicle equipped with suspension dampers variable of damping coefficient, including: a means for storing a group of schedules each having a plurality of information units for controlling the variation of the damping coefficient of the damper; a means for generating a new schedule by hybridizing more than one of the schedules selected from the group according to a predetermined genetic algorithm including mutation based upon a fictionalization that the schedules are living individuals each having the plurality of information units as a set of genes; a means for evaluating each of the schedules under current operation environment of the vehicle to determine the ranking of the schedules in the group in improving a predetermined performance of the suspension; a means for adopting a highest ranked schedule for controlling the damping coefficient of the damper; a means for deleting a lowest ranked schedule to keep the number of the schedules forming the group substantially constant; and a means for generating a control signal for controlling the damper based upon the highest ranked schedule.
摘要翻译：一种用于车辆的悬架控制装置，其具有可变阻尼系数的悬挂阻尼器，包括：用于存储一组调度表的装置，每个调度表具有用于控制阻尼器的阻尼系数变化的多个信息单元; 一种用于通过根据包含基于虚构化的虚构化的预定遗传算法从组中选出的多于一个的时间表来选择一个以上的多个信息单元作为一组基因的生活个体来产生新时间表的装置; 在车辆的当前操作环境下评估每个时间表的装置，以确定组中的时间表的排名，以改善暂停的预定性能; 采用排名最高的控制阻尼系数阻尼系数的方法; 一种用于删除排名最低的日程表以保持形成该组的日程表数量基本上恒定的方法; 以及用于基于最高排序的时间表产生用于控制阻尼器的控制信号的装置。

2. 发明授权

US08222405B2 Phenylalanine derivatives 有权
标题翻译：苯丙氨酸衍生物
公开(公告)号：US08222405B2
公开(公告)日：2012-07-17
申请号：US12951180
申请日：2010-11-22
申请人： Shingo Makino , Tatsuya Okuzumi , Toshihiko Yoshimura , Yuko Satake , Nobuyasu Suzuki , Hiroyuki Izawa , Kazuyuki Sagi , Akira Chiba , Eiji Nakanishi , Masahiro Murata , Takashi Tsuji
发明人： Shingo Makino , Tatsuya Okuzumi , Toshihiko Yoshimura , Yuko Satake , Nobuyasu Suzuki , Hiroyuki Izawa , Kazuyuki Sagi , Akira Chiba , Eiji Nakanishi , Masahiro Murata , Takashi Tsuji
IPC分类号： C07D285/24 , C07D239/72 , C07D403/04 , C07D253/08 , C07D265/26 , C07D487/04
CPC分类号： C07D239/22 , C07D239/54 , C07D239/78 , C07D239/80 , C07D239/91 , C07D239/95 , C07D239/96 , C07D253/08 , C07D265/26 , C07D285/16 , C07D285/24 , C07D401/12 , C07D471/04 , C07D475/02 , C07D487/04 , Y02P20/582
摘要： Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin.
摘要翻译：指定的苯丙氨酸衍生物及其类似物对α4整联蛋白具有拮抗作用。它们被用作关于α4整联蛋白的各种疾病的治疗剂。

3. 发明申请

US20110065918A1 NEW PHENYLALANINE DERIVATIVES 有权
标题翻译：新的苯乙烯胺衍生物
公开(公告)号：US20110065918A1
公开(公告)日：2011-03-17
申请号：US12951180
申请日：2010-11-22
申请人： Shingo MAKINO , Tatsuya Okuzumi , Toshihiko Yoshimura , Yuko Satake , Nobuyasu Suzuki , Hiroyuki Izawa , Kazuyuki Sagi , Akira Chiba , Eiji Nakanishi , Masahiro Murata , Takashi Tsuji
发明人： Shingo MAKINO , Tatsuya Okuzumi , Toshihiko Yoshimura , Yuko Satake , Nobuyasu Suzuki , Hiroyuki Izawa , Kazuyuki Sagi , Akira Chiba , Eiji Nakanishi , Masahiro Murata , Takashi Tsuji
IPC分类号： C07D285/24 , C07D239/72 , C07D403/04 , C07D253/08 , C07D265/26 , C07D487/04 , C07D239/54
CPC分类号： C07D239/22 , C07D239/54 , C07D239/78 , C07D239/80 , C07D239/91 , C07D239/95 , C07D239/96 , C07D253/08 , C07D265/26 , C07D285/16 , C07D285/24 , C07D401/12 , C07D471/04 , C07D475/02 , C07D487/04 , Y02P20/582
摘要： Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin.
摘要翻译：指定的苯丙氨酸衍生物及其类似物对α4整联蛋白具有拮抗作用。它们被用作关于α4整联蛋白的各种疾病的治疗剂。

4. 发明授权

US07872125B2 Phenylalanine derivatives 有权
标题翻译：苯丙氨酸衍生物
公开(公告)号：US07872125B2
公开(公告)日：2011-01-18
申请号：US11442141
申请日：2006-05-30
申请人： Shingo Makino , Tatsuya Okuzumi , Toshihiko Yoshimura , Yuko Satake , Nobuyasu Suzuki , Hiroyuki Izawa , Kazuyuki Sagi , Akira Chiba , Eiji Nakanishi , Masahiro Murata , Takashi Tsuji
发明人： Shingo Makino , Tatsuya Okuzumi , Toshihiko Yoshimura , Yuko Satake , Nobuyasu Suzuki , Hiroyuki Izawa , Kazuyuki Sagi , Akira Chiba , Eiji Nakanishi , Masahiro Murata , Takashi Tsuji
IPC分类号： A61K31/517 , C07D239/96
CPC分类号： C07D239/22 , C07D239/54 , C07D239/78 , C07D239/80 , C07D239/91 , C07D239/95 , C07D239/96 , C07D253/08 , C07D265/26 , C07D285/16 , C07D285/24 , C07D401/12 , C07D471/04 , C07D475/02 , C07D487/04 , Y02P20/582
摘要： Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin.
摘要翻译：指定的苯丙氨酸衍生物及其类似物对α4整联蛋白具有拮抗作用。它们被用作关于α4整联蛋白的各种疾病的治疗剂。

5. 发明申请

US20090048236A1 NEW PHENYLALANINE DERIVATIVES 失效
标题翻译：新的苯乙烯胺衍生物
公开(公告)号：US20090048236A1
公开(公告)日：2009-02-19
申请号：US12253060
申请日：2008-10-16
申请人： Nobuyasu SUZUKI , Toshihiko Yoshimura , Hiroyuki Izawa , Kazuyuki Sagi , Shingo Makino , Eiji Nakanishi , Masahiro Murata , Takashi Tsuji
发明人： Nobuyasu SUZUKI , Toshihiko Yoshimura , Hiroyuki Izawa , Kazuyuki Sagi , Shingo Makino , Eiji Nakanishi , Masahiro Murata , Takashi Tsuji
IPC分类号： A61K31/4035 , C07D209/48 , A61K31/55 , A61P37/00 , A61P9/00 , C07D223/18
CPC分类号： C07D207/452 , A61K31/395 , A61K31/4015 , A61K31/403 , A61K31/4035 , A61K31/435 , A61K31/4355 , A61K31/4365 , A61K31/437 , A61K31/438 , A61K31/4412 , A61K31/45 , A61K31/472 , A61K31/48 , A61K31/4985 , A61K31/55 , C07D207/38 , C07D209/46 , C07D209/48 , C07D209/52 , C07D209/66 , C07D209/76 , C07D211/88 , C07D217/24 , C07D217/26 , C07D221/14 , C07D221/20 , C07D223/10 , C07D223/18 , C07D403/12 , C07D471/04 , C07D487/04 , C07D495/04
摘要： Specific phenylalanine derivatives or pharmaceutically acceptable salts thereof have an antagonistic effect on the α4 integrins and, therefore, are usable as therapeutic agents or preventive agents for diseases in which α4 integrin-depending adhesion process participates in the pathology, such as inflammatory diseases, rheumatoid arthritis, inflammatory bowel diseases, systemic lupus erythematosus, multiple sclerosis, Sjögren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis, restenosis, tumor proliferation, tumor metastasis and transplantation rejection.
摘要翻译：特定的苯丙氨酸衍生物或其药学上可接受的盐对α4整联蛋白具有拮抗作用，因此可用作治疗剂或预防药物，其中α4整联蛋白依赖性粘附过程参与病理学，例如炎症性疾病，类风湿性关节炎炎症性肠病，系统性红斑狼疮，多发性硬化症，Sjögren综合征，哮喘，牛皮癣，过敏，糖尿病，心血管疾病，动脉硬化，再狭窄，肿瘤增殖，肿瘤转移和移植排斥。

6. 发明授权

US07452905B2 Phenylalanine derivatives 有权
标题翻译：苯丙氨酸衍生物
公开(公告)号：US07452905B2
公开(公告)日：2008-11-18
申请号：US10402006
申请日：2003-03-31
申请人： Nobuyasu Suzuki , Toshihiko Yoshimura , Eiji Nakanishi , Masahiro Murata , Takashi Tsuji
发明人： Nobuyasu Suzuki , Toshihiko Yoshimura , Eiji Nakanishi , Masahiro Murata , Takashi Tsuji
IPC分类号： A61K31/47 , C07D471/10 , C07D221/04
CPC分类号： C07D207/452 , A61K31/395 , A61K31/4015 , A61K31/403 , A61K31/4035 , A61K31/435 , A61K31/4355 , A61K31/4365 , A61K31/437 , A61K31/438 , A61K31/4412 , A61K31/45 , A61K31/472 , A61K31/48 , A61K31/4985 , A61K31/55 , C07D207/38 , C07D209/46 , C07D209/48 , C07D209/52 , C07D209/66 , C07D209/76 , C07D211/88 , C07D217/24 , C07D217/26 , C07D221/14 , C07D221/20 , C07D223/10 , C07D223/18 , C07D403/12 , C07D471/04 , C07D487/04 , C07D495/04
摘要： Specific phenylalanine derivatives or pharmaceutically acceptable salts thereof have an antagonistic effect on the α 4 integrins and, therefore, are usable as therapeutic agents or preventive agents for diseases in which α 4 integrin-depending adhesion process participates in the pathology, such as inflammatory diseases, rheumatoid arthritis, inflammatory bowel diseases, systemic lupus erythematosus, multiple sclerosis, Sjögren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis, restenosis, tumor proliferation, tumor metastasis and transplantation rejection.
摘要翻译：特定的苯丙氨酸衍生物或其药学上可接受的盐对α4整联蛋白具有拮抗作用，因此可用作治疗剂或其中α4整联蛋白依赖性粘附过程参与病理学的疾病的预防剂，例如炎性疾病，类风湿关节炎，炎性肠病，系统性红斑狼疮，多发性硬化症，Sjögren综合征，哮喘，牛皮癣，过敏，糖尿病，心血管疾病，动脉硬化，再狭窄，肿瘤增生，肿瘤转移和移植排斥。

7. 发明授权

US07291402B2 Surface-treated steel sheets of good white rust resistance, and method for producing them 失效
标题翻译：表面处理好的耐白锈锈钢板及其制造方法
公开(公告)号：US07291402B2
公开(公告)日：2007-11-06
申请号：US10515303
申请日：2003-02-14
申请人： Okai Kazuhisa , Akira Matsuzaki , Naoto Yoshimi , Takahiro Kubota , Masaaki Yamashita , Hisato Noro , Haruo Nakamichi , Kaoru Sato , Hiroyasu Matsuki , Reijiro Nishida , Masahiro Murata , Shoichi Tanaka , Yoshikazu Morohoshi , Shingo Amaki
发明人： Okai Kazuhisa , Akira Matsuzaki , Naoto Yoshimi , Takahiro Kubota , Masaaki Yamashita , Hisato Noro , Haruo Nakamichi , Kaoru Sato , Hiroyasu Matsuki , Reijiro Nishida , Masahiro Murata , Shoichi Tanaka , Yoshikazu Morohoshi , Shingo Amaki
IPC分类号： B32B15/08 , B32B15/092 , B32B15/18 , B32B15/20 , B05D3/02
CPC分类号： C23C22/08 , B05D7/56 , B05D2202/10 , B05D2350/65 , C08G59/4035 , C09D5/08 , C09D163/00 , C23C22/12 , C23C22/18 , C23C22/20 , C23C22/22 , C23C22/34 , C23C22/42 , C23C2222/20 , Y10T428/12569 , Y10T428/12611 , Y10T428/12757 , Y10T428/12799 , Y10T428/12951 , Y10T428/24967 , Y10T428/265 , Y10T428/31529 , Y10T428/31663 , Y10T428/31678 , C08L2666/28 , C08L2666/20 , C08L2666/54
摘要： The invention is to provide a surface-treated steel sheet of good white rust resistance with no chromium in its surface treatment film, and it has realized a surface-treated steel sheet of higher-level corrosion resistance by forming a reaction layer of plating metal with a barrier layer effective for anticorrosion not in a two-layered film but in a single-layered film. The surface-treated steel sheet is fabricated by applying a surface-treating composition that contains: (a) a water-dispersible resin and/or a water-soluble resin obtained through reaction of an epoxy group-containing resin (A) with an active hydrogen-containing compound (B) a part or all of which is an active hydrogen-containing hydrazine derivative and preferably with a hydrophilic organic component (C), (b) a silane coupling agent, (c) a phosphoric acid and/or a hexafluoro-metal acid, and (d) preferably an aqueous dispersion of an urethane resin, to a zinc-plated or aluminium-plated steel sheet followed by drying it to form thereon a surface treatment film having a thickness of from 0.02 to 5 μm. Regarding its film structure, the surface treatment film comprises an amorphous compound layer containing P, Zn and/or Al, and O, and an overlying organic resin matrix layer where the matrix is a hydrazine derivative-modified epoxy group-containing resin or the epoxy group-containing resin and an urethane resin.
摘要翻译：本发明提供一种在其表面处理膜中不产生铬的耐白锈锈的表面处理钢板，通过形成电镀金属的反应层，实现了具有较高耐腐蚀性的表面处理钢板不是在双层膜中而是在单层膜中有效地防腐蚀的阻挡层。表面处理钢板通过涂布表面处理组合物制造，所述表面处理组合物包含：（a）通过含环氧基的树脂（A）与活性物质的反应获得的水分散性树脂和/或水溶性树脂含氢化合物（B）的一部分或全部为含活性氢的肼衍生物，优选具有亲水性有机成分（C），（b）硅烷偶联剂，（c）磷酸和/或六氟金属酸，（d）优选为聚氨酯树脂的水分散体，涂布到镀锌或镀铝钢板上，然后干燥，形成厚度为0.02〜5μm的表面处理膜。关于其膜结构，表面处理膜包括含有P，Zn和/或Al和O的无定形化合物层，以及基质是含有肼衍生物改性的含环氧基的树脂或环氧树脂的上覆有机树脂基质层含有基团的树脂和聚氨酯树脂。

8. 发明申请

US20070031898A1 Kit for determining polysaccharide-binding ability of mononuclear cells present in peripheral blood 有权
标题翻译：用于测定外周血中存在的单核细胞的多糖结合能力的试剂盒
公开(公告)号：US20070031898A1
公开(公告)日：2007-02-08
申请号：US11580936
申请日：2006-10-16
申请人： Tetsuya Suga , Yasuyo Suga , Masahiro Murata
发明人： Tetsuya Suga , Yasuyo Suga , Masahiro Murata
IPC分类号： G01N33/567 , A61K31/716
CPC分类号： G01N33/56972 , G01N2400/10 , Y10S435/975
摘要： A kit for the determination of the ability of a peripheral blood mononuclear cell to bind to a polysaccharide herein provided comprises a detection reagent comprising a fluorescence-labeled immunostimulant polysaccharide; and a reference reagent comprising a fluorescence-labeled material of a polysaccharide different from that used in the fluorescence-labeled immunostimulant polysaccharide, and/or an immunostimulant polysaccharide which is not labeled with any fluorescent material and whose polysaccharide moiety is identical to that included in the fluorescence-labeled immunostimulant polysaccharide. The use of this kit would permit the estimation of the polysaccharide-binding ability of a peripheral blood mononuclear cell in a higher precision of estimation.
摘要翻译：用于测定外周血单核细胞与本文提供的多糖结合的能力的试剂盒包括含有荧光标记的免疫刺激多糖的检测试剂; 和包含不同于荧光标记的免疫刺激多糖中使用的多糖的荧光标记物质的参考试剂，和/或未用任何荧光材料标记的多糖部分与其中包含的多糖部分相同的免疫刺激多糖荧光标记免疫刺激多糖。该试剂盒的使用将允许以更高的估计精度估计外周血单核细胞的多糖结合能力。

9. 发明申请

US20060141230A1 Highly corrosion-resistant surface-treated steel sheet and method for producing same 失效
公开(公告)号：US20060141230A1
公开(公告)日：2006-06-29
申请号：US10559641
申请日：2004-06-14
申请人： Tatsuya Miyoshi , Kenichi Sasaki , Naoto Yoshimi , Akira Matsuzaki , Kazuhisa Okai , Takao Ooshima , Takashi Nakano , Masahiro Murata , Syoichi Tanaka
发明人： Tatsuya Miyoshi , Kenichi Sasaki , Naoto Yoshimi , Akira Matsuzaki , Kazuhisa Okai , Takao Ooshima , Takashi Nakano , Masahiro Murata , Syoichi Tanaka
IPC分类号： B32B15/092 , B32B15/18
CPC分类号： C23C28/00 , C09D163/00 , C23C2/26 , C23C2222/20 , Y02T50/67 , Y10T428/12569 , Y10T428/12757 , Y10T428/12799 , Y10T428/24967 , Y10T428/24975 , Y10T428/265 , Y10T428/31529 , Y10T428/31551 , Y10T428/31612 , Y10T428/31678 , C08L2666/54
摘要： The surface-treated steel sheet has a zinc-based plated steel sheet, a surface-treatment coating being formed on the surface of the zinc-based steel sheet by applying and drying a surface treatment coating composition thereon, and a top coating being formed by applying and drying a coating composition for top coating on the surface-treatment coating. The surface treatment coating composition contains a water-epoxy resin dispersion, a silane coupling agent, and phosphoric acid and/or a hexafluorometal acid. The coating composition for top coating contains a high molecular weight epoxy group-containing resin having number average molecular weights ranging from 6000 to 20000.

10. 发明申请

US20050170613A1 Wafer dividing method 有权
标题翻译：晶圆分割法
公开(公告)号：US20050170613A1
公开(公告)日：2005-08-04
申请号：US11047585
申请日：2005-02-02
申请人： Masahiro Murata , Yusuke Nagai , Yukio Morishige , Satoshi Kobayashi , Naoki Ohmiya
发明人： Masahiro Murata , Yusuke Nagai , Yukio Morishige , Satoshi Kobayashi , Naoki Ohmiya
IPC分类号： B23K26/00 , B23K26/40 , B23K101/40 , B28D5/00 , H01L21/301 , H01L21/46 , H01L21/68 , H01L21/78 , H05K3/00
CPC分类号： H01L21/6836 , B23K26/40 , B23K26/57 , B23K2101/40 , B23K2103/50 , B28D5/0011 , B28D5/0052 , H01L21/78 , H01L2221/68327
摘要： A method of dividing, along dividing lines, a wafer having function elements formed in areas sectioned by the dividing lines formed in a lattice pattern on the front surface, comprising: a frame holding step for affixing the back surface of the wafer to a dicing tape mounted on an annular frame; a deteriorated layer forming step for forming a deteriorated layer along the dividing lines in the inside of the wafer by applying a pulse laser beam capable of passing through the wafer to the wafer along the dividing lines, from the side of the front surface of the wafer held on the frame; a dividing step for dividing the wafer into individual chips along the dividing lines by exerting external force along the dividing lines where the deteriorated layers have been formed of the wafer held on the frame; an expansion step for enlarging the interval between chips by stretching the dicing tape affixed to the wafer divided into individual chips; and a picking up step for picking up each chip from the expanded dicing tape.
摘要翻译：沿着分割线划分具有由在前表面上以格子图案形成的分割线划分的区域中形成的功能元件的晶片的方法，包括：框架保持步骤，用于将晶片的背面固定到切割带安装在环形框架上; 劣化层形成步骤，用于通过从晶片的前表面侧沿分割线施加能够穿过晶片的脉冲激光束沿晶片内部的分割线形成劣化层; 在框架上举行分割步骤，通过沿着由保持在框架上的晶片形成劣化层的分割线施加外力，沿着分割线将晶片分割成单个芯片; 扩展步骤，用于通过拉伸固定到划分成单个芯片的晶片上的切割带来扩大芯片之间的间隔; 以及用于从扩展的切割胶带拾取每个芯片的拾取步骤。

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