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1. 发明申请

US20130102617A1 METHOD OF TREATING DIABETES, METABOLIC SYNDROME AND OBESITY USING PHENYLACETAMIDE DERIVATIVE 审中-公开
标题翻译：治疗糖尿病的方法，代谢综合征和使用苯乙胺衍生物的成分
公开(公告)号：US20130102617A1
公开(公告)日：2013-04-25
申请号：US13449401
申请日：2012-04-18
申请人： Masahiko Hayakawa , Yoshiyuki Kido , Takahiro Nigawara , Mitsuaki Okumura , Akira Kanai , Keisuke Maki , Nobuaki Amino
发明人： Masahiko Hayakawa , Yoshiyuki Kido , Takahiro Nigawara , Mitsuaki Okumura , Akira Kanai , Keisuke Maki , Nobuaki Amino
IPC分类号： C07D405/12 , C07D413/08 , C07D231/40 , C07D417/12 , C07D213/75 , C07D405/14 , C07D513/04 , C07D241/20 , C07D261/14 , C07D239/42 , C07D285/135 , C07D413/06 , C07D277/46
CPC分类号： C07D405/12 , C07D213/75 , C07D213/80 , C07D231/40 , C07D239/42 , C07D241/20 , C07D241/26 , C07D241/28 , C07D261/14 , C07D263/48 , C07D277/46 , C07D277/54 , C07D277/56 , C07D285/08 , C07D285/135 , C07D405/14 , C07D409/12 , C07D413/06 , C07D413/08 , C07D413/12 , C07D417/12 , C07D513/04
摘要： Phenylacetamide compounds of the formula having sulfonyl group and cycloalkyl group on the phenyl group and having heteroaryl group on the nitrogen atom in the amide have an excellent glucokinase activation action. The compound of the present invention is useful as an agent for treating diabetes, in particular, type II diabetes, as well as metabolic syndrome and obesity.
摘要翻译：具有磺酰基和环烷基的苯基乙酰胺化合物在苯基上并且在酰胺的氮原子上具有杂芳基具有优异的葡糖激酶活化作用。本发明的化合物可用作治疗糖尿病，特别是II型糖尿病以及代谢综合征和肥胖症的药剂。

2. 发明授权

US08329707B2 Substituted pyrazine compounds 有权
标题翻译：取代的吡嗪化合物
公开(公告)号：US08329707B2
公开(公告)日：2012-12-11
申请号：US12812385
申请日：2009-01-16
申请人： Masahiko Hayakawa , Yoshiyuki Kido , Takahiro Nigawara , Mitsuaki Okumura , Akira Kanai , Keisuke Maki , Nobuaki Amino
发明人： Masahiko Hayakawa , Yoshiyuki Kido , Takahiro Nigawara , Mitsuaki Okumura , Akira Kanai , Keisuke Maki , Nobuaki Amino
IPC分类号： A61K31/4965
CPC分类号： C07D405/12 , C07D213/75 , C07D213/80 , C07D231/40 , C07D239/42 , C07D241/20 , C07D241/26 , C07D241/28 , C07D261/14 , C07D263/48 , C07D277/46 , C07D277/54 , C07D277/56 , C07D285/08 , C07D285/135 , C07D405/14 , C07D409/12 , C07D413/06 , C07D413/08 , C07D413/12 , C07D417/12 , C07D513/04
摘要： Phenylacetamide compounds of the formula having sulfonyl group and cycloalkyl group on the phenyl group and having heteroaryl group on the nitrogen atom in the amide have an excellent glucokinase activation action.
摘要翻译：具有磺酰基和环烷基的苯基乙酰胺化合物在苯基上并且在酰胺的氮原子上具有杂芳基具有优异的葡糖激酶活化作用。

3. 发明申请

US20100286171A1 PHENYLACETAMIDE DERIVATIVE 有权
标题翻译：苯甲酰胺衍生物
公开(公告)号：US20100286171A1
公开(公告)日：2010-11-11
申请号：US12812385
申请日：2009-01-16
申请人： Masahiko Hayakawa , Yoshiyuki Kido , Takahiro Nigawara , Mitsuaki Okumura , Akira Kanai , Keisuke Maki , Nobuaki Amino
发明人： Masahiko Hayakawa , Yoshiyuki Kido , Takahiro Nigawara , Mitsuaki Okumura , Akira Kanai , Keisuke Maki , Nobuaki Amino
IPC分类号： A61K31/497 , C07D407/12 , A61K31/443 , C07D413/10 , A61K31/422 , C07D277/46 , A61K31/426 , C07D277/54 , C07D241/20 , A61K31/4965 , C07D231/40 , A61K31/415 , C07D285/135 , A61K31/433 , C07D239/42 , A61K31/505 , C07D495/04 , A61K31/437 , A61P3/00 , A61P3/04 , A61P3/10
CPC分类号： C07D405/12 , C07D213/75 , C07D213/80 , C07D231/40 , C07D239/42 , C07D241/20 , C07D241/26 , C07D241/28 , C07D261/14 , C07D263/48 , C07D277/46 , C07D277/54 , C07D277/56 , C07D285/08 , C07D285/135 , C07D405/14 , C07D409/12 , C07D413/06 , C07D413/08 , C07D413/12 , C07D417/12 , C07D513/04
摘要： A phenylacetamide derivative having sulfonyl group and cycloalkyl group on the phenyl group and having heteroaryl group on the nitrogen atom in the amide has an excellent GK activation action, thereby completing the present invention. The compound of the present invention is useful as an agent for treating diabetes, in particular, type II diabetes, since it has an excellent GK activation action.
摘要翻译：在苯基上具有磺酰基和环烷基的苯乙酰胺衍生物在酰胺中的氮原子上具有杂芳基具有优异的GK活化作用，从而完成了本发明。本发明的化合物可用作治疗糖尿病，特别是II型糖尿病的药剂，因为它具有优异的GK活化作用。

4. 发明授权

US4523410A Composite guide mechanism 失效
标题翻译：复合导向机构
公开(公告)号：US4523410A
公开(公告)日：1985-06-18
申请号：US564782
申请日：1983-12-27
申请人： Junichi Yoshioka , Koichi Koizumi , Akira Kanai , Kazuo Shiba
发明人： Junichi Yoshioka , Koichi Koizumi , Akira Kanai , Kazuo Shiba
IPC分类号： B23Q1/26 , B23Q1/38 , F16C29/02 , B24B41/00
CPC分类号： F16C32/06 , B23Q1/38 , F16C29/025 , B29K2105/06 , B29L2023/003 , B29L2023/18
摘要： In a machine tool such as a surface grinding machine or the like, a guide mechanism for the machine tool wherein one of a pair of opposed guideways is formed into a hydrodynamic guideway, whilst the other guideway is formed into a hydrostatic guideway, the hydrodynamic guideway is utilized as only one master guide, and on the other hand, the hydrostatic guideway is made to act in such that a moving body is pushed onto the hydrodynamic guideway with a constant pressure, so that this arrangement makes uniform the contact pressure distribution in the hydrodynamic guideway, thus the posture of the moving body is improved thereby making the same to perform precision linear motion.
摘要翻译：在诸如表面磨床等的机床中，用于机床的引导机构，其中一对相对的导轨中的一个形成为流体动力导轨，而另一导轨形成为静压导轨，流体动力导轨仅用于一个主导向器，另一方面，使静液压导轨作用成使得移动体以恒定的压力被推到流体动力导轨上，使得这种布置使接触压力分布均匀流体动力导轨，因此提高了移动体的姿势，从而使其相同地进行精密的直线运动。

5. 发明授权

US4656951A Rotary table unit 失效
标题翻译：旋转台单元
公开(公告)号：US4656951A
公开(公告)日：1987-04-14
申请号：US737267
申请日：1985-05-23
申请人： Sosaku Kimura , Toshikazu Hatsuse , Masami Shimizu , Masakazu Miyashita , Junichi Yoshioka , Akira Kanai , Koichi Koizumi
发明人： Sosaku Kimura , Toshikazu Hatsuse , Masami Shimizu , Masakazu Miyashita , Junichi Yoshioka , Akira Kanai , Koichi Koizumi
IPC分类号： B23Q1/38 , B23Q1/52 , B23Q5/38 , A47B45/00
CPC分类号： B23Q5/385 , B23Q1/38 , B23Q1/522
摘要： A rotary table unit having a stationary base element and a table element rotatably mounted on the stationary base element is provided with hydrostatic and hydrodynamic bearing guides forming a composite bearing guide mechanism for enabling smooth and stable rotation of the table element under application of local load to the table element. The rotary table unit is also provided with a main drive motor for rotating the table element and an auxiliary drive motor for supplementing a drive force of the main drive motor in response to a change in load applied to the table element.
摘要翻译：具有固定基座元件和可旋转地安装在固定基座元件上的工作台元件的旋转台单元设置有静压和流体动力轴承引导件，其形成复合轴承引导机构，用于在施加局部负载的情况下使台式元件平稳和稳定地旋转表元素。旋转台单元还设置有用于使桌子元件旋转的主驱动马达和辅助驱动马达，用于补偿主驱动马达的驱动力，以响应施加到台元件的负载变化。

6. 发明申请

US20070073514A1 Walking analyzer 审中-公开
标题翻译：步行分析仪
公开(公告)号：US20070073514A1
公开(公告)日：2007-03-29
申请号：US11526769
申请日：2006-09-26
申请人： Wataru Nogimori , Hideaki Yamaguchi , Mitsutoshi Uematsu , Akira Kanai
发明人： Wataru Nogimori , Hideaki Yamaguchi , Mitsutoshi Uematsu , Akira Kanai
IPC分类号： G01C22/00 , G01B11/02 , G01B11/14
CPC分类号： G01C22/006 , A61B5/1038 , A61B5/1117 , A61B5/224 , A61B5/4528 , A61B2562/0219
摘要： A walking analyzer includes an acceleration sensor detecting an up-down acceleration, a front-rear acceleration, and a right-left acceleration of a person, an acceleration change calculating device for calculating changes of each acceleration in time, a time period extracting device extracting a certain time period in which a certain walking movement is performed on the basis of the changes of the acceleration in time of one of the up-down acceleration, the front-rear acceleration and the right-left acceleration, an estimated indicator calculating device calculating an estimated indicator related to a walking ability and a walking ability estimating device estimating a walking ability by use of the estimated indicator and by use of a predetermined relation between an estimated indicator and a walking ability.
摘要翻译：步行分析器包括检测人的上下加速度，前后加速度和左右加速度的加速度传感器，用于计算每个加速时间的变化的加速度变化计算装置，时间段提取装置提取基于上下加速度，前后加速度和右后加速度之一的时间加速度的变化执行某个步行运动的一定时间段，估计指标计算装置计算与步行能力相关的估计指标和行走能力估计装置，通过使用估计指标和使用估计指标与行走能力之间的预定关系来估计行走能力。

7. 发明授权

US6034666A System and method for displaying a color picture 失效
标题翻译：用于显示彩色图像的系统和方法
公开(公告)号：US6034666A
公开(公告)日：2000-03-07
申请号：US905277
申请日：1997-08-06
申请人： Akira Kanai , Masaki Yamakawa
发明人： Akira Kanai , Masaki Yamakawa
IPC分类号： H04N9/31 , G09G1/28 , G09G5/02 , G09G5/20
CPC分类号： H04N9/47 , G09G1/04 , G09G1/165 , G09G3/001 , G09G5/02 , G09G5/04 , H04N9/18 , G09G2310/0224 , G09G2310/0235 , G09G5/005 , G09G5/18 , G09G5/399
摘要： A system for displaying a color picture. This system has a field sequential signal generator for receiving and storing a color picture signal, which includes a plurality of signal components per field, at a first rate and sequentially sending the plurality of signal components, as a field sequential signal, at a second rate which is higher than the first rate; a picture display for displaying a monochromatic picture based on each of the signal components; a coloring device for coloring light emitted from the monochromatic picture displayed on the picture display; and a controller for sending a vertical sync signal, which includes a plurality of vertical sync pulses corresponding to the signal components respectively, to the picture display. The controller controls a timing at which each of the vertical sync pulses is sent to the picture display in such a way that respective time intervals between when the vertical sync pulse is sent from the controller to the picture display and when the signal component is sent from the field sequential signal generator to the picture display are equal.
摘要翻译：用于显示彩色图像的系统。该系统具有场顺序信号发生器，用于以第一速率接收和存储彩色图像信号，其包括每场的多个信号分量，并以第二速率顺序发送多个信号分量作为场顺序信号高于第一率; 用于基于每个信号分量显示单色图像的图像显示器; 着色装置，用于着色在图像显示器上显示的单色图像发出的光; 以及控制器，用于向图像显示器发送包括分别对应于信号分量的多个垂直同步脉冲的垂直同步信号。控制器控制每个垂直同步脉冲被发送到图像显示器的定时，使得垂直同步脉冲从控制器发送到图像显示器之间的时间间隔以及信号分量从图像显示的场顺序信号发生器相等。

8. 发明授权

US4528074A Method for producing a grinding wheel by electroplating 失效
标题翻译：电镀砂轮生产方法
公开(公告)号：US4528074A
公开(公告)日：1985-07-09
申请号：US585293
申请日：1984-03-01
申请人： Masakazu Miyashita , Akira Kanai , Junichi Yoshioka , Koichi Koizumi , Fukuo Hashimoto , Michimasa Daito , Takashi Hasebe
发明人： Masakazu Miyashita , Akira Kanai , Junichi Yoshioka , Koichi Koizumi , Fukuo Hashimoto , Michimasa Daito , Takashi Hasebe
IPC分类号： C25D1/00 , C25D15/00
CPC分类号： C25D15/00
摘要： Disclosed is a method of producing a grinding wheel by electroplating. A part of the outer peripheral portion of a grinding wheel body is immersed in a plating solution. While rotating the grinding wheel body at a low speed, electric current is supplied to flow between an anode disposed in the plating solution and a cathode contacting the grinding wheel body, so that a pre-plating layer of uniform thickness is formed on the outer peripheral surface of the grinding wheel body. Plating operation is continued while adhering abrasive grains to the pre-plating layer to further cause a precipitation of a plating layer to temporarily fix the abrasive grains. The abrasive grains are then pressed by a pressing roller so as to be forcibly embedded into the pre-plating layer by making an effective use of plastic deformation of the pre-plating layer, thereby to obtain a uniform projection height of the abrasive grains from the surface of the grinding wheel. Then, a final plating is conducted to finally fix the abrasive grains. Disclosed also is an apparatus suitable for use in carrying out this method.
摘要翻译：公开了通过电镀制造砂轮的方法。研磨轮体的外周部的一部分浸渍在电镀液中。在低速旋转砂轮体的同时，供给电流以在布置在电镀溶液中的阳极与接触砂轮主体的阴极之间流动，从而在外周形成均匀厚度的预镀层磨轮表面。在将磨粒粘附到预镀层上的同时继续进行电镀操作，以进一步引起镀层的沉淀以暂时固定磨粒。然后通过加压辊压制磨粒，通过有效地利用预镀层的塑性变形将其强制地嵌入到预镀层中，从而获得磨粒的均匀突出高度砂轮表面。然后进行最终电镀以最终固定磨粒。还公开了适用于实施该方法的装置。

9. 发明授权

US4193644A Servo control system 失效
标题翻译：伺服控制系统
公开(公告)号：US4193644A
公开(公告)日：1980-03-18
申请号：US890908
申请日：1978-03-28
申请人： Masakazu Miyashita , Akira Kanai
发明人： Masakazu Miyashita , Akira Kanai
IPC分类号： B23Q1/38 , F16C32/06 , G05D3/12 , F16C35/00
CPC分类号： F16C32/0648 , B23Q1/385 , G05D3/12
摘要： A servo control system which can automatically control a position of a hydrostatically supported member such as a table of a machine tool, rotary shaft or the like is disclosed. The system comprises a closed loop control system including a differential amplifier for effecting a subtraction operation between an amount of displacement of a member and an amount of reference signal and a servo amplifier delivering a control signal and a servovalve for supplying operating pressure upon receipt of the control signal to the member, whereby the position of the member is controlled by the pressure applied thereto.
摘要翻译：公开了一种能够自动控制诸如机床，旋转轴等的静电支撑构件的位置的伺服控制系统。该系统包括闭环控制系统，其包括差分放大器，用于在部件的位移量与参考信号量之间进行减法运算，以及传送控制信号的伺服放大器和用于在接收到运算压力时提供运行压力的伺服阀控制信号到构件，从而通过施加到构件的压力来控制构件的位置。

10. 发明授权

US07655528B2 Manufacturing method of semiconductor device 有权
标题翻译：半导体器件的制造方法
公开(公告)号：US07655528B2
公开(公告)日：2010-02-02
申请号：US10588959
申请日：2005-01-17
申请人： Satoshi Eguchi , Akira Kanai , Isao Miyashita , Seigo Nagashima
发明人： Satoshi Eguchi , Akira Kanai , Isao Miyashita , Seigo Nagashima
IPC分类号： H01L21/331
CPC分类号： H01L29/78 , H01L21/0237 , H01L21/02529 , H01L21/02532 , H01L21/02573 , H01L21/02579 , H01L21/0262 , H01L21/02639 , H01L29/1054 , H01L29/66242
摘要： SiH3CH3 having the concentration of 1 to 10% is diluted with H2 and a portion of the diluted SiH3CH3, GeH4 and SiH4 (or DCS) are respectively supplied to a chamber of an epitaxial device at predetermined flow rates, and SiGe:C is formed by an epitaxial growth technique. By diluting the SiH3CH3, the concentration of oxygen-based impurity contained in the SiH3CH3 is reduced and hence, the oxygen-based impurity which is supplied to a chamber are reduced whereby the concentration of oxygen-based impurity contained in the SiGe:C formed in a film is reduced.
摘要翻译：浓度为1〜10％的SiH 3 CH 3用H2稀释，一部分稀释的SiH 3 CH 3，GeH 4和SiH 4（或DCS）分别以规定的流量供给到外延装置的室，SiGe：C由外延生长技术。通过稀释SiH 3 CH 3，SiH 3 CH 3中含有的氧基杂质的浓度降低，因此供给到室的氧系杂质减少，由此形成SiGe:C中含有的氧基杂质的浓度一部电影减少了。

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