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2. 发明授权

US4761268A Liquid handling 失效
标题翻译：液体处理
公开(公告)号：US4761268A
公开(公告)日：1988-08-02
申请号：US599509
申请日：1984-04-12
申请人： Marlo R. Andersen , Thomas O. Tiffany , Mario J. Gangitano
发明人： Marlo R. Andersen , Thomas O. Tiffany , Mario J. Gangitano
IPC分类号： G01N1/00 , G01N35/04 , G01N35/10 , G01N21/07 , G01N35/06
CPC分类号： G01N35/1002 , G01N2035/0443 , G01N2035/0446 , G01N2035/0448 , G01N35/1083 , G01N35/1095
摘要： A liquid handling system that is particularly useful in a clinical analysis system includes a cuvette loading station for receiving a centrifugal analyzer rotor with two compartment cuvettes. Fixedly mounted on transfer structure are two spaced apart liquid handling probes such that the two probes may be simultaneously inserted into the two compartments of an analysis cuvette. A sample station has a sample container support mechanism, and means for indexing the support mechanism past the sample station for sequentially positioning successive sample containers at the sample station. An auxiliary station that is spaced from the sample station a distance corresponding to the spacing of the two probes includes a support mechanism for supporting a plurality of auxiliary containers and a drive mechanism for selectively positioning auxiliary containers at the auxiliary station. A first drive provides relative movement between the transfer structure and the loading sample and auxiliary stations; a second drive is adapted to concurrently insert the tips of the two liquid handling probes into containers at the loading, sample or auxiliary stations. First and second liquid metering means are coupled to the probes by storage chamber structure so that each metering means controls the flow of a liquid into and out of its storage chamber through its probe; and control means operate the drive mechanisms and the liquid metering means in coordinated manner to transfer sample and reagent materials from sample and auxiliary containers at the sample and auxiliary stations to an analysis cuvette at the loading station. The system provides coordinated automatic pipetting and transfer of sample, diluent and reagent liquids in rapid, efficient and precise manner.
摘要翻译：在临床分析系统中特别有用的液体处理系统包括用于接收具有两个隔室比色皿的离心分析器转子的反应杯装载站。固定安装在转移结构上的是两个间隔开的液体处理探针，使得两个探针可以同时插入分析比色皿的两个隔室中。样品台具有样品容器支持机构，以及用于将支撑机构分度通过样品台的装置，用于将连续样品容器顺序地定位在样品台。与采样站间隔开的与两个探针的间隔相对应的距离的辅助站包括用于支撑多个辅助容器的支撑机构和用于在辅助站处选择性地定位辅助容器的驱动机构。第一驱动器提供传送结构和装载样本和辅助站之间的相对运动; 第二驱动器适于同时将两个液体处理探针的尖端插入装载，取样或辅助站中的容器中。第一和第二液体计量装置通过储存室结构联接到探针，使得每个计量装置通过其探针控制液体进出其储存室的流动; 并且控制装置以协调的方式操作驱动机构和液体计量装置，以将样品和试剂材料从样品和辅助站处的样品和辅助容器转移到装载站处的分析试管中。该系统以快速，高效和精确的方式提供了样品，稀释剂和试剂液体的协调自动移液和转移。

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