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1. 发明授权

US5695524A Constant width, adjustable grip, staple apparatus and method 失效
标题翻译：恒定宽度，可调握柄，装订装置和方法
公开(公告)号：US5695524A
公开(公告)日：1997-12-09
申请号：US538001
申请日：1995-10-02
申请人： Mark Kelley , Phil McDuffie
发明人： Mark Kelley , Phil McDuffie
IPC分类号： A61B17/064 , A61B17/068 , A61B17/10 , A61B17/04
CPC分类号： A61B17/10 , A61B17/0644 , A61B17/0686 , Y10S227/902 , Y10S411/92
摘要： A staple and stapler for injecting the staple in a manner so that the staple maintains a near constant width upon penetration of material to be joined and during staple closure/forming such that material perturbation and staple to staple spacing may be minimized. The staple has a rectilinear bridge part from which depend oppositely positioned side parts and from the side parts a pair of straight legs. In a preferred embodiment, the oppositely positioned side parts consist of a proximal arcuate section attached to the bridge part and an oppositely directed distal arcuate section attached to the legs. The legs may have sharpened points. Also disclosed is a stapler adapted to force the oppositely directed distal arcuate sections outward, in one embodiment, thereby forcing a reaction of the legs of the staple to face each other in linear alignment and form a closed staple. The unpreloaded fully-formed staple may be deformed in situ by means of a preload part on a cam slide so as to create a U-shaped central portion for the compression of captured material. Alternatively, a preformed staple with the U-shaped central portion may also be used.
摘要翻译：一种钉和订书机，用于以这样的方式注射订书钉，使得订书钉在待接合的材料穿透时以及在缝合期间/成型期间保持接近恒定的宽度，使得材料扰动和订书针至订书钉的间隔可以最小化。订书钉具有直线桥部分，从该位置的相对定位的侧部和从侧面部分是一对直的腿。在优选实施例中，相对定位的侧面部分由附接到桥接部分的近端弧形部分和附接到腿部的相反方向的远端弧形部分组成。腿可能有磨尖点。还公开了一种订书机，其在一个实施例中适合于将相对方向的远端弓形部分向外强制，由此迫使订书针的腿部以线性对准的方式彼此面对并形成封闭的订书钉。未加载的完全成型的订书钉可以通过凸轮滑块上的预加载部分原位变形，以便形成用于压缩所捕获材料的U形中心部分。或者，还可以使用具有U形中心部分的预制钉。

2. 发明授权

US08965871B2 System and method for providing targeted content to a user based on user characteristics 有权
标题翻译：基于用户特征向用户提供有针对性的内容的系统和方法
公开(公告)号：US08965871B2
公开(公告)日：2015-02-24
申请号：US13166708
申请日：2011-06-22
申请人： Mark Kelley , Steven John Caliguri , Souheil Gallouzi
发明人： Mark Kelley , Steven John Caliguri , Souheil Gallouzi
IPC分类号： H04L29/08 , G06Q30/02 , H04W4/18 , H04W4/02
CPC分类号： H04L67/20 , G06Q30/02 , H04L67/306 , H04W4/02 , H04W4/18
摘要： A system and method for providing a personalized advertisement for a good or service for display to a user is described. The system includes a communications device operated by the user; a virtual person database comprising information about the user; and a search engine useful for finding advertisements of interest to the user and generating personalized advertisements for display on the communications device.
摘要翻译：描述了一种为用户提供个性化广告以供显示给用户的系统和方法。该系统包括由用户操作的通信设备; 虚拟人数据库，其包括关于用户的信息; 以及搜索引擎，用于查找用户感兴趣的广告并且生成用于在通信设备上显示的个性化广告。

3. 发明申请

US20130164779A1 DISPOSABLE CARTRIDGE FOR FLUID ANALYSIS 有权
标题翻译：用于流体分析的可拆卸盒
公开(公告)号：US20130164779A1
公开(公告)日：2013-06-27
申请号：US13337916
申请日：2011-12-27
申请人： Mark Kelley , Ron Bardell , Robert Janisch , Pam Wong , Eric Peltola
发明人： Mark Kelley , Ron Bardell , Robert Janisch , Pam Wong , Eric Peltola
IPC分类号： C12Q1/06 , C12M1/34 , G01N33/48
CPC分类号： G01N33/5094 , B01L3/502738 , B01L2200/10 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2300/0883 , B01L2400/0406 , B01L2400/049 , B01L2400/0655 , Y10T436/11
摘要： A disposable blood analysis cartridge may include a sample collection reservoir, an absorbance measurement channel, and an optical light scattering measurement channel. One or more valves may be disposed between the sample collection reservoir and the absorbance measurement channel and/or the optical light scattering measurement channel. A negative pressure may be applied to the cartridge to pull sample from the sample collection reservoir through the one or more valves and into the absorbance measurement channel and/or the optical light scattering measurement channel. Once the sample is pulled into the absorbance measurement channel and/or the optical light scattering measurement channel, the one or more valves may be closed. With the one or more valves closed, and in some cases, a pusher fluid may be provided to push the fluid sample to other regions of the disposable fluid blood analysis cartridge.
摘要翻译：一次性血液分析盒可以包括样品收集容器，吸光度测量通道和光学散射测量通道。一个或多个阀可以设置在样品收集容器和吸光度测量通道和/或光学光散射测量通道之间。可以向盒施加负压，以将样品从样品收集容器中通过一个或多个阀拉入吸光度测量通道和/或光学光散射测量通道。一旦将样品拉入吸光度测量通道和/或光学散射测量通道中，则可以关闭一个或多个阀。在一个或多个阀关闭的情况下，并且在一些情况下，可以提供推动器流体以将流体样本推送到一次性液体血液分析盒的其它区域。

4. 发明申请

US20050219631A1 Methods and apparatus for electronically trapping digital images 有权
标题翻译：用于电子捕获数字图像的方法和装置
公开(公告)号：US20050219631A1
公开(公告)日：2005-10-06
申请号：US10718211
申请日：2003-11-20
申请人： Yigal Accad , Richard Falk , Mark Kelley
发明人： Yigal Accad , Richard Falk , Mark Kelley
IPC分类号： H04N1/58
CPC分类号： H04N1/58
摘要： Methods and apparatus are provided for electronically trapping a selected digital color image pixel. A plurality of pixels that surround the selected pixel are identified, a colorant value of each of the surrounding pixels is compared with a corresponding colorant value of the selected pixel, one of the surrounding pixels is identified to control trapping of the selected pixel, and the selected pixel is trapped based on a relationship between a colorant value of the selected pixel and a corresponding colorant value of the identified controlling pixel.
摘要翻译：提供了用于电子捕获所选择的数字彩色图像像素的方法和装置。识别围绕所选择的像素的多个像素，将每个周围像素的着色剂值与所选择的像素的相应着色剂值进行比较，识别周围像素中的一个以控制所选择的像素的捕获，基于所选择的像素的着色剂值和所识别的控制像素的相应着色剂值之间的关系来捕获所选择的像素。

5. 发明授权

US6046036A DNA sequences encoding fusions of DNA repair proteins and uses thereof 失效
标题翻译：编码DNA修复蛋白融合物的DNA序列及其用途
公开(公告)号：US6046036A
公开(公告)日：2000-04-04
申请号：US957302
申请日：1997-10-24
申请人： Mark Kelley , David Williams
发明人： Mark Kelley , David Williams
IPC分类号： A61K38/00 , C12N9/00 , C12N9/10 , C12N9/18 , C12N15/00 , C07H21/04 , C12N15/63 , C12N15/85
CPC分类号： C12N9/1007 , C12N9/18 , C12N9/93 , A01K2217/05 , A61K38/00 , C07K2319/00
摘要： Described are DNA-repair fusion proteins of multiple, complementary DNA repair proteins and having the activity of each protein, and related polynucleotides and vectors. The proteins, when expressed in cells, e.g., hematopoietic cells, increase the survival rate of the cells when contacted with chemotherapeutic agents. Also described are transgenic animal models wherein these proteins are expressed in essentially all cells of the animal. Such animal models are useful for instance in testing chemotherapeutic agents.
摘要翻译：描述了多个互补DNA修复蛋白的DNA修复融合蛋白，并具有每种蛋白质的活性，以及相关的多核苷酸和载体。当在细胞中表达的蛋白质例如造血细胞当与化学治疗剂接触时增加细胞的存活率。还描述了其中这些蛋白质在动物的基本上所有细胞中表达的转基因动物模型。这样的动物模型在例如化学治疗剂的测试中是有用的。

6. 发明授权

US5715987A Constant width, adjustable grip, staple apparatus and method 失效
标题翻译：恒定宽度，可调握柄，装订装置和方法
公开(公告)号：US5715987A
公开(公告)日：1998-02-10
申请号：US641835
申请日：1996-05-02
申请人： Mark Kelley , Phil McDuffie
发明人： Mark Kelley , Phil McDuffie
IPC分类号： A61B17/064 , A61B17/068
CPC分类号： A61B17/0644
摘要： A staple and stapler for injecting the staple in a manner so that the staple maintains a near constant width upon penetration of material to be joined and during staple closure/forming such that material perturbation and staple to staple spacing may be minimized. The staple has a rectilinear bridge part from which depend oppositely positioned side parts and from the side parts a pair of straight legs. In a preferred embodiment, the oppositely positioned side parts consist of a proximal arcuate section attached to the bridge part and an oppositely directed distal arcuate section attached to the legs. The legs may have sharpened points. Also disclosed is a stapler adapted to force the oppositely directed distal arcuate sections outward, in one embodiment, thereby forcing a reaction of the legs of the staple to face each other in linear alignment and form a closed staple. The unpreloaded fully-formed staple may be deformed in situ by means of a preload part on a cam slide so as to create a U-shaped central portion for the compression of captured material. Alternatively, a preformed staple with the U-shaped central portion may also be used.
摘要翻译：一种钉和订书机，用于以这样的方式注射订书钉，使得订书钉在待接合的材料穿透时以及在缝合期间/成型期间保持接近恒定的宽度，使得材料扰动和订书针至订书钉的间隔可以最小化。订书钉具有直线桥部分，从该位置的相对定位的侧部和从侧面部分是一对直的腿。在优选实施例中，相对定位的侧面部分由附接到桥接部分的近端弧形部分和附接到腿部的相反方向的远端弧形部分组成。腿可能有磨尖点。还公开了一种订书机，其在一个实施例中适合于将相对方向的远端弓形部分向外强制，由此迫使订书针的腿部以线性对准的方式彼此面对并形成封闭的订书钉。未加载的完全成型的订书钉可以通过凸轮滑块上的预加载部分原位变形，以便形成用于压缩所捕获材料的U形中心部分。或者，还可以使用具有U形中心部分的预制钉。

7. 发明授权

US09360412B2 Rotating optics for multiple cuvette array 有权
标题翻译：用于多个比色皿阵列的旋转光学元件
公开(公告)号：US09360412B2
公开(公告)日：2016-06-07
申请号：US13678990
申请日：2012-11-16
申请人： Mark Kelley
发明人： Mark Kelley
IPC分类号： G01N21/03 , G01N21/01
CPC分类号： G01N21/01
摘要： A system includes a testing instrument to hold a test card having multiple cuvettes radially spaced about a point on the card. A rotatable mount is supported in relation the point on the card when the card is held in the testing system. Optics are supported on the rotatable mount to provide radiation to the multiple cuvettes.
摘要翻译：一种系统包括一个测试仪器，用于保持测试卡，该测试卡具有围绕卡上点的径向间隔开的多个比色皿。当卡被保持在测试系统中时，相对于卡上的点来支持可旋转的支架。可转动支架支持光学元件，为多个比色皿提供辐射。

8. 发明申请

US20060106368A1 Smart Surgical Device Operating System With Radio Frequency Identification 审中-公开
标题翻译：智能手术设备操作系统与射频识别
公开(公告)号：US20060106368A1
公开(公告)日：2006-05-18
申请号：US10904530
申请日：2004-11-15
申请人： Ronald Miller , Hanaan Elmessiri , Scott Dulchavsky , Ilan Rubinfeld , Mark Kelley
发明人： Ronald Miller , Hanaan Elmessiri , Scott Dulchavsky , Ilan Rubinfeld , Mark Kelley
IPC分类号： A61B17/00
CPC分类号： A61B90/90 , A61B90/98
摘要： A smart surgical device (10) for use during an operating procedure includes a surgical apparatus (12) that aids in the facilitation of an operating procedure. A body internal readable control circuit (14) is coupled and stores identification information related to the surgical apparatus (12).
摘要翻译：在操作过程中使用的智能手术装置（10）包括有助于促进操作程序的手术装置（12）。身体内部可读控制电路（14）被连接并存储与手术装置（12）有关的识别信息。

9. 发明授权

US4882533A Linear integrated circuit voltage drop generator having a base-10-emitter voltage independent current source therein 失效
标题翻译：线性集成电路压降发生器，其中具有基极 - 发射极电压独立的电流源
公开(公告)号：US4882533A
公开(公告)日：1989-11-21
申请号：US312373
申请日：1989-02-15
申请人： Mark Kelley
发明人： Mark Kelley
IPC分类号： G05F3/26
CPC分类号： G05F3/265 , Y10S323/907
摘要： A voltage drop generator having a current source having reduced sensitivity to transistor base-emitter voltage process and temperature induced variations, is used to generate a precise voltage drop across a resistor. Transistor emitter area ratios are selected and an additional resistance is used in conjunction with the selected ratios to reduce the sensitivity (of the output voltage drop) to base-emitter voltages, to provide substantial improvement in process and temperature dependent output variations.
摘要翻译：使用具有对晶体管基极 - 发射极电压处理和温度诱导的变化具有降低的灵敏度的电流源的电压降发生器，以在电阻器两端产生精确的电压降。选择晶体管发射极面积比，并且使用额外的电阻与所选择的比率相结合，以降低基极 - 发射极电压的灵敏度（输出电压降），从而显着改善工艺和温度相关输出变化。

10. 发明授权

US09289761B2 Card waste storage mechanism 有权
标题翻译：卡废物储存机制
公开(公告)号：US09289761B2
公开(公告)日：2016-03-22
申请号：US13678925
申请日：2012-11-16
申请人： Mark Kelley , Ron Bardell , Tighe Belden
发明人： Mark Kelley , Ron Bardell , Tighe Belden
IPC分类号： B01L1/00 , B01L3/00
CPC分类号： B01L1/50 , B01L3/502723 , B01L2200/0684 , B01L2200/082 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0406 , B01L2400/086 , Y10T137/0318 , Y10T156/1002
摘要： A multiple layer test card includes a waste channel to receive biological waste from an area of the test card utilized for testing biological samples. Multiple compartments in a waste layer of the card are separated from each other by a rib in the waste layer. A first compartment is positioned to receive biological waste from the waste channel. A pass is coupled between each adjacent set of compartments to pass biological waste and air between compartments. A vent in a last compartment provides an air exit from the card.
摘要翻译：多层测试卡包括从用于测试生物样品的测试卡的区域接收生物废物的废物通道。卡的废物层中的多个隔室通过废物层中的肋条彼此分离。定位第一隔室以从废物通道接收生物废物。在每个相邻的隔间组之间连接通道以在隔室之间传递生物废物和空气。最后一个隔间内的通风口提供了卡的空气出口。

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