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1. 发明授权

US06237498B1 Pyrotechnical inflator and method of making same 失效
标题翻译：火焰充气机及其制作方法
公开(公告)号：US06237498B1
公开(公告)日：2001-05-29
申请号：US09111134
申请日：1998-07-03
申请人： Marc Winterhalder , Paul Adam , Martin Fink , Markus Leifheit
发明人： Marc Winterhalder , Paul Adam , Martin Fink , Markus Leifheit
IPC分类号： B60R2126
CPC分类号： B60R21/2644 , B60R2021/2633 , B60R2021/2648
摘要： An inflator, more particularly for a vehicle occupant restraint system, has a tubular inflator housing which is closed off at its end faces and has radial exit ports via which the gas is able to exit the inflator. The inflator housing has in its interior at least one combustion chamber packed with propellant, at least one ignition unit for igniting the propellant in the combustion chamber and at least one filter which is located upstream of the exit ports. A filter insert featuring an outer housing is provided, the outer housing having a plurality of housing parts which at least partly surround the filter disposed in the filter insert. The outer housing together with its housing parts is radially secured to the inflator housing without the provision of an axial stop. The outer geometry of the outer housing and the inner geometry of the inflator housing permit total insertion of the outer housing or its housing parts in the axial direction into the inflator housing to different insertion depths when the outer housing is still in the non-secured condition.
摘要翻译：更具体地，对于车辆乘员约束系统的充气机具有管状充气机壳体，其在其端面处被封闭，并具有径向出口，气体能够通过该出口端口离开充气机。充气机壳体在其内部具有装有推进剂的至少一个燃烧室，用于点燃燃烧室中的推进剂的至少一个点火单元和位于出口端口上游的至少一个过滤器。提供具有外壳的过滤器插入件，所述外壳具有至少部分围绕设置在过滤器插入件中的过滤器的多个壳体部分。外壳与其壳体部件一起径向地固定到充气机壳体上，而不需要提供轴向止动。外壳体的外部几何形状和充气机壳体的内部几何形状允许当外部壳体仍处于非固定状态时，将外部壳体或其壳体部件沿轴向全部插入到充气器壳体中到不同的插入深度。

2. 发明授权

US10179810B2 Anti-IGF antibodies 有权
公开(公告)号：US10179810B2
公开(公告)日：2019-01-15
申请号：US14304338
申请日：2014-06-13
申请人： Paul Adam , Eric Borges , Robert Rauchenberger , Gabriela Wochnik-Veltrup
发明人： Paul Adam , Eric Borges , Robert Rauchenberger , Gabriela Wochnik-Veltrup
IPC分类号： A61K39/395 , C07K16/22 , A61K31/282 , A61K33/24 , A61K45/06 , A61K31/436 , A61K31/517 , G01N33/574 , A61K39/00
摘要： Antibody molecules, in particular fully human antibodies that bind to human IGF-1 and cross-react with IGF-2 such that binding of IGF-1 and IGF-2 to the IGF-1 receptor is prevented and IGF-1 receptor-mediated signaling is inhibited. The antibodies do not bind to insulin and thus do not affect the mitogenic properties of insulin that are mediated by its binding to the insulin receptors. The antibodies are useful for the treatment of hyperproliferative diseases, in particular cancer.

3. 发明授权

US08956139B2 Mold system for forming multilevel blocks 有权
标题翻译：用于形成多层块的模具系统
公开(公告)号：US08956139B2
公开(公告)日：2015-02-17
申请号：US14318048
申请日：2014-06-27
申请人： Paul Adam
发明人： Paul Adam
IPC分类号： B28B3/08 , B28B7/24 , B29C43/34 , A01G1/08 , B28B3/06
CPC分类号： B28B3/083 , A01G9/28 , B28B3/06 , B28B7/0097 , B28B7/24
摘要： A mold system for forming a multilevel block is disclosed which comprises a multilevel mold box insert for forming a multilevel block, a mold box frame adapted for receiving therein the multilevel mold box insert, a multilevel plunger assembly, and a press head plate adapted for receiving thereon the multilevel plunger assembly.
摘要翻译：公开了一种用于形成多级块的模具系统，其包括用于形成多级块的多级模具盒插入件，适于在其中容纳多级模具盒插入件的多个模具箱框架，多级柱塞组件和适于接收在其上的多级柱塞组件。

4. 发明申请

US20060117697A1 Modular block system 有权
标题翻译：模块化系统
公开(公告)号：US20060117697A1
公开(公告)日：2006-06-08
申请号：US10994859
申请日：2004-11-22
申请人： Paul Adam
发明人： Paul Adam
IPC分类号： E04C2/04
CPC分类号： E04C1/395 , E04B2002/0245 , E04B2002/026 , E04B2002/0263
摘要： A modular block system comprises a first block, a second block, a third block, a fourth block, and a capstone, the first block having a front face, a back face, a first side, a second side, a top, and a bottom, with the front face being wider than the back face and the first side being slanted from the front face toward the back face, the second block having a front face, a back face, a first side, a second side, a top, and a bottom, with the front face being wider than the back face and the first and second sides being slanted from the front face toward the back face, the third block having a front face, a back face, a first side, a second side, a top, and a bottom, with the front face being wider than the back face and the first side being slanted from the front face toward the back face, and the fourth block having a front face, a back face, a first side, a second side, a top, and a bottom, with the front face being wider than the back face and the first side and the second side being from the front face toward the back face.
摘要翻译：模块化块系统包括第一块，第二块，第三块，第四块和盖石，第一块具有正面，背面，第一侧，第二侧，顶部和顶部底部，其前表面比后表面宽，并且第一侧面从前表面向后表面倾斜，第二块具有正面，背面，第一面，第二面，顶部，和底部，其前表面比后表面宽，并且第一和第二侧面从前表面向后表面倾斜，第三块具有前表面，后表面，第一侧，第二侧顶部和底部，其前表面比后表面宽，并且第一侧面从前表面向后表面倾斜，并且第四块具有前表面，后表面，第一侧面，第二面，顶部和底部，前表面比背面宽，第一面和第二面bei 从前面朝向背面。

5. 发明授权

US08580254B2 Anti-IGF antibodies 有权
标题翻译：抗IGF抗体
公开(公告)号：US08580254B2
公开(公告)日：2013-11-12
申请号：US12665373
申请日：2008-06-19
申请人： Paul Adam , Elinborg Ostermann
发明人： Paul Adam , Elinborg Ostermann
IPC分类号： A61K39/395 , C07K16/22
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/21 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： Antibody molecules, in particular fully human antibodies that bind to human IGF-1 and cross-react with IGF-2 such that binding of IGF-1 and IGF-2 to the IGF-1 receptor is prevented and IGF-1 receptor-mediated signaling is inhibited. The antibodies do not bind to insulin and thus do not affect the mitogenic properties of insulin that are mediated by its binding to the insulin receptors. The antibodies are useful for the treatment of hyperproliferative diseases, in particular cancer.
摘要翻译：抗体分子，特别是与人IGF-1结合并与IGF-2交叉反应的完全人类抗体，使得IGF-1和IGF-2与IGF-1受体的结合被阻止，并且IGF-1受体介导的信号传导被抑制。抗体不结合胰岛素，因此不影响胰岛素与胰岛素受体结合介导的促有丝分裂特性。抗体可用于治疗过度增生性疾病，特别是癌症。

6. 外观设计

USD620135S1 Modular block system 有权
标题翻译：模块化系统
公开(公告)号：USD620135S1
公开(公告)日：2010-07-20
申请号：US29316487
申请日：2009-10-03
申请人： Paul Adam
设计人： Paul Adam
CPC分类号： E04C1/395 , E04B2002/0245 , E04B2002/026 , E04B2002/0263

7. 外观设计

USD546478S1 Paver stone 有权
标题翻译：摊铺石
公开(公告)号：USD546478S1
公开(公告)日：2007-07-10
申请号：US29254355
申请日：2006-02-22
申请人： Paul Adam
设计人： Paul Adam

8. 发明申请

US20060233610A1 Interlocking paver stone system 审中-公开
标题翻译：联锁摊铺机石系统
公开(公告)号：US20060233610A1
公开(公告)日：2006-10-19
申请号：US11104837
申请日：2005-04-13
申请人： Paul Adam
发明人： Paul Adam
IPC分类号： E01C5/00
CPC分类号： E01C5/06 , E01C2201/06
摘要： An interlocking paver stone system comprises a first paver stone having a generally oval configuration and a second paver stone having a generally star configuration having a first point, a second point, a third point, a fourth point, a first curved side between the first point and the second point, a second curved side between the second point and the third point, a third curved side between the third point and the fourth point, and a fourth curved side between the fourth point and the first point.
摘要翻译：一种互锁摊铺机石系统，包括具有大致椭圆形构造的第一摊铺机石头和具有通常具有第一点，第二点，第三点，第四点，第一点第二点，第二点和第三点之间的第二弯曲侧，第三点与第四点之间的第三弯曲侧，第四点与第一点之间的第四弯曲侧。

9. 发明申请

US20140308383A1 MOLD SYSTEM FOR FORMING MULTILEVEL BLOCKS 有权
标题翻译：用于形成多块块的模具系统
公开(公告)号：US20140308383A1
公开(公告)日：2014-10-16
申请号：US14318048
申请日：2014-06-27
申请人： Paul Adam
发明人： Paul Adam
IPC分类号： B28B3/08 , B28B3/06
CPC分类号： B28B3/083 , A01G9/28 , B28B3/06 , B28B7/0097 , B28B7/24
摘要： A mold system for forming a multilevel block is disclosed which comprises a multilevel mold box insert for forming a multilevel block, a mold box frame adapted for receiving therein the multilevel mold box insert, a multilevel plunger assembly, and a press head plate adapted for receiving thereon the multilevel plunger assembly.
摘要翻译：公开了一种用于形成多级块的模具系统，其包括用于形成多级块的多级模具盒插入件，适于在其中容纳多级模具盒插入件的多个模具箱框架，多级柱塞组件和适于接收在其上的多级柱塞组件。

10. 发明申请

US20130129853A1 MOLD SYSTEM FOR FORMING MULTILEVEL BLOCKS 有权
标题翻译：用于形成多块块的模具系统
公开(公告)号：US20130129853A1
公开(公告)日：2013-05-23
申请号：US13742968
申请日：2013-01-16
申请人： Paul Adam
发明人： Paul Adam
IPC分类号： B28B3/08
CPC分类号： B28B3/083 , A01G9/28 , B28B3/06 , B28B7/0097 , B28B7/24
摘要： A mold system for forming a multilevel block is disclosed which comprises a multilevel mold box insert for forming a multilevel block, a mold box frame adapted for receiving therein the multilevel mold box insert, a multilevel plunger assembly, and a press head plate adapted for receiving thereon the multilevel plunger assembly.
摘要翻译：公开了一种用于形成多级块的模具系统，其包括用于形成多级块的多级模具盒插入件，适于在其中容纳多级模具盒插入件的多个模具箱框架，多级柱塞组件和适于接收在其上的多级柱塞组件。

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