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1. 发明授权

US06248934B1 Gene trap vectors 有权
标题翻译：基因陷阱载体
公开(公告)号：US06248934B1
公开(公告)日：2001-06-19
申请号：US09191652
申请日：1998-11-13
申请人： Marc Tessier-Lavigne , William C. Skarnes , Kevin Mitchell , Philip A. Leighton
发明人： Marc Tessier-Lavigne , William C. Skarnes , Kevin Mitchell , Philip A. Leighton
IPC分类号： C12N1500
CPC分类号： C12N15/1051 , A01K2217/05 , C07K2319/02 , C07K2319/03 , C07K2319/04 , C07K2319/60 , C12N15/62 , C12N15/85 , C12N2800/60 , C12N2840/203 , C12N2840/44 , C12Q1/6897
摘要： The invention provides methods and compositions for expressing targeted gene products in vertebrate neurons. The compositions include gene trap vectors comprising a polynucleotide comprising promoterless selectable marker and axon reporter encoding sequences, which may be operatively joined to an internal ribosome-entry site, and may comprise a splice acceptor site located 5′ to the selectable marker and axon reporter encoding sequences. The methods include methods of expressing an axon reporter in a cell by transferring the subject vectors into an embryonic stem cell and incubating the cell under conditions whereby the cell or a progeny of the cell differentiates into a neuron comprising an axon or dendrites, and the neuron expresses the axon reporter under the transcriptional control of the gene; and specifically detecting the axon reporter in the axon or dendrites. Neuronal specific expression may also be effected in disclosed binary systems.
摘要翻译：本发明提供用于在脊椎动物神经元中表达靶基因产物的方法和组合物。组合物包括基因捕获载体，其包含多核苷酸，其包含无启动子选择标记和轴突报道子编码序列，其可以可操作地连接到内部核糖体进入位点，并且可以包含位于选择性标记5'的剪接受体位点和轴突报告基因编码序列。所述方法包括通过将受试载体转移到胚胎干细胞中并在细胞或细胞的后代分化为包含轴突或树突的神经元和神经元的条件下孵育细胞来在细胞中表达轴突报告物的方法在基因的转录控制下表达轴突记者; 并具体检测轴突或树突中的轴突记录。神经元特异性表达也可以在公开的二元系统中进行。

2. 发明申请

US20170228740A1 EVALUATING A PLACEMENT OF OPTICAL FIRE DETECTOR(S) BASED ON A PLUME MODEL 审中-公开
公开(公告)号：US20170228740A1
公开(公告)日：2017-08-10
申请号：US15429625
申请日：2017-02-10
申请人： Edward Marszal , Sean Cunningham , Kevin Mitchell
发明人： Edward Marszal , Sean Cunningham , Kevin Mitchell
IPC分类号： G06Q30/00 , G06F17/50 , G06Q10/06 , G08B29/18 , G08B17/103
摘要： The aspects disclosed herein are directed to systems, methods, implementations, and devices for evaluating the efficacy of optical fire placement(s) with a plume-based model. Employing the aspects disclosed herein, an implementer may review a real-world implementation and determine if said real-world implementation is covered adequately by a proposed optical fire placement strategy.

3. 发明申请

US20130311999A1 RESOURCE MANAGEMENT SUBSYSTEM THAT MAINTAINS FAIRNESS AND ORDER 有权
标题翻译：资源管理子系统维护公平和秩序
公开(公告)号：US20130311999A1
公开(公告)日：2013-11-21
申请号：US13476791
申请日：2012-05-21
申请人： Michael FETTERMAN , Shirish Gadre , John H. Edmondson , Omkar Paranjape , Anjana Rajendran , Eric Lyell Hill , Rajeshwaran Selvanesan , Charles McCarver , Kevin Mitchell , Steven James Heinrich
发明人： Michael FETTERMAN , Shirish Gadre , John H. Edmondson , Omkar Paranjape , Anjana Rajendran , Eric Lyell Hill , Rajeshwaran Selvanesan , Charles McCarver , Kevin Mitchell , Steven James Heinrich
IPC分类号： G06F9/50
CPC分类号： G06F9/5011 , G06F2209/507
摘要： One embodiment of the present disclosure sets forth an effective way to maintain fairness and order in the scheduling of common resource access requests related to replay operations. Specifically, a streaming multiprocessor (SM) includes a total order queue (TOQ) configured to schedule the access requests over one or more execution cycles. Access requests are allowed to make forward progress when needed common resources have been allocated to the request. Where multiple access requests require the same common resource, priority is given to the older access request. Access requests may be placed in a sleep state pending availability of certain common resources. Deadlock may be avoided by allowing an older access request to steal resources from a younger resource request. One advantage of the disclosed technique is that older common resource access requests are not repeatedly blocked from making forward progress by newer access requests.
摘要翻译：本公开的一个实施例阐述了在与重放操作相关的公共资源访问请求的调度中维持公平性和顺序的有效方式。具体地说，流式多处理器（SM）包括配置成通过一个或多个执行周期调度访问请求的总顺序队列（TOQ）。访问请求被允许在需要时将共同资源分配给该请求来进行进展。在多个访问请求需要相同的公共资源的情况下，优先级被赋予较旧的访问请求。访问请求可能处于睡眠状态，等待某些公共资源的可用性。可以通过允许较旧的访问请求从较年轻的资源请求中窃取资源来避免死锁。所公开的技术的一个优点是较旧的公共资源访问请求不被重复阻止以通过较新的访问请求提前进展。

4. 发明申请

US20120090119A1 WET WIPES AND METHODS FOR MAKING SAME 审中-公开
标题翻译：湿织物及其制造方法
公开(公告)号：US20120090119A1
公开(公告)日：2012-04-19
申请号：US13272748
申请日：2011-10-13
申请人： Michael Edward Carrier , John Allen Manifold , Khosrow Parviz Mohammadi , Kevin Mitchell
发明人： Michael Edward Carrier , John Allen Manifold , Khosrow Parviz Mohammadi , Kevin Mitchell
IPC分类号： A47K7/03
CPC分类号： C11D17/049
摘要： Wet wipes formed from a fibrous structure and a liquid composition that exhibit novel properties are provided.
摘要翻译：提供由纤维结构形成的湿巾和表现出新颖性质的液体组合物。

5. 发明授权

US08001539B2 Historical data management 有权
标题翻译：历史数据管理
公开(公告)号：US08001539B2
公开(公告)日：2011-08-16
申请号：US11712065
申请日：2007-02-28
申请人： Kevin Mitchell
发明人： Kevin Mitchell
IPC分类号： G06F9/44 , G06F9/45
CPC分类号： G06F17/30551
摘要： An apparatus and method for managing historical data includes receiving a compiled application program and a declarative specification. An enhancer generates one or more representations of at least one data class defined in the application program based on at least one historical metatag and historical metadata associated therewith from the declarative specification. The enhancer also generates configuring instructions for configuring a database in accordance with the storage representation(s), an enhanced compiled application program including instructions for accessing data in the configured database, and a historical updater program for updating the data in the database based on the historical metadata. Once the database is configured in accordance with the configuring instructions and data is stored in accordance with the storage representation(s), the enhanced compiled application program is executed to access the database so as to retrieve historical data therefrom and the historical updater program is executed to update the data in the database based on the historical metadata.
摘要翻译：用于管理历史数据的装置和方法包括接收编译的应用程序和声明性规范。基于与声明性规范相关联的至少一个历史元标签和历史元数据，增强器生成在应用程序中定义的至少一个数据类别的一个或多个表示。该增强器还生成用于根据存储表示配置数据库的配置指令，包括用于访问所配置的数据库中的数据的指令的增强编译应用程序，以及用于基于该数据库更新数据库中的数据的历史更新程序历史元数据一旦根据配置指令配置数据库，并且根据存储表示存储数据，则执行增强编译的应用程序以访问数据库，以从其中检索历史数据，并执行历史更新程序根据历史元数据更新数据库中的数据。

6. 发明授权

US07059004B2 Floor surface treatment apparatus 失效
标题翻译：地板表面处理设备
公开(公告)号：US07059004B2
公开(公告)日：2006-06-13
申请号：US10216582
申请日：2002-08-09
申请人： Kevin Mitchell , John L. Obenshain
发明人： Kevin Mitchell , John L. Obenshain
IPC分类号： A47L11/293
CPC分类号： A47L11/4055
摘要： A floor surface treatment apparatus having a wheeled vehicle including a support for a floor surface treatment unit, the support being moveable relative to the vehicle. A floor surface treatment unit is pivotally carried by the support for swinging movement relative thereto. The support is configured to raise and lower the unit relative to the floor surface, upon movement of the support relative to the vehicle, through a range of working positions in which the unit maintains a generally vertical orientation relative to the floor surface and is generally in contact therewith and a servicing position in which the unit is swung up relative to the vehicle above the floor surface to a position in which the unit is generally angled relative to the floor surface.
摘要翻译：一种具有轮式车辆的地板表面处理装置，其包括用于地板表面处理单元的支撑件，所述支撑件能够相对于所述车辆移动。地板表面处理单元由支撑件枢转地支承，以相对于其摆动运动。支撑件被配置为在支撑件相对于车辆移动时，相对于地板表面升高和降低单元通过一定范围的工作位置，在该范围内，该单元保持相对于地板表面的大致垂直的取向，并且通常在与其接触和维修位置，其中单元相对于地板表面上方的车辆向上摆动到该单元相对于地板表面大体成角度的位置。

7. 发明申请

US20060083179A1 Probe apparatus and metod therefor 审中-公开
标题翻译：探测仪器和仪器
公开(公告)号：US20060083179A1
公开(公告)日：2006-04-20
申请号：US11229232
申请日：2005-09-16
申请人： Kevin Mitchell
发明人： Kevin Mitchell
IPC分类号： H04J1/16
CPC分类号： H04L43/50 , H04L41/0813 , H04L41/0823 , H04L43/12
摘要： A probe for a communications network is arranged to implement an aggregate test constituted from a plurality of individual tests, and to optimise modifications to the aggregate test with respect to an optimisation goal.
摘要翻译：用于通信网络的探测器被布置成实现由多个单独测试构成的聚合测试，并且针对优化目标优化对聚合测试的修改。

8. 发明申请

US20050281259A1 Method of generating a monitoring datagram 审中-公开
标题翻译：生成监控数据报的方法
公开(公告)号：US20050281259A1
公开(公告)日：2005-12-22
申请号：US11129188
申请日：2005-05-13
申请人： Kevin Mitchell
发明人： Kevin Mitchell
IPC分类号： H04L12/24 , H04L12/26 , H04L12/701 , H04L12/723 , H04L12/56
CPC分类号： H04L45/00 , H04L41/0213 , H04L43/026 , H04L45/502
摘要： A method of generating a monitoring datagram for a predetermined network includes generating an initial datagram and encapsulating the initial datagram with a shim header, where the shim header has a first shim entry and a second shim entry, the first and second shim entries are associated with the predetermined network, the first shim entry is next to and follows the second shim entry, and where the first shim entry identifies the initial datagram as having a monitoring status.
摘要翻译：生成预定网络的监视数据报的方法包括：生成初始数据报并用垫片头部封装初始数据报，其中垫片头部具有第一垫片条目和第二垫片条目，第一和第二垫片条目与所述预定网络，所述第一垫片条目在所述第二垫片条目旁边并且跟随所述第一垫片入口，并且其中所述第一垫片条目将所述初始数据报识别为具有监视状态。

9. 发明授权

US08881272B2 System and method for selecting and applying filters for intrusion protection system within a vulnerability management system 有权
标题翻译：在漏洞管理系统中选择和应用入侵保护系统的过滤器的系统和方法
公开(公告)号：US08881272B2
公开(公告)日：2014-11-04
申请号：US12726492
申请日：2010-03-18
申请人： Eva Bunker , Nelson Bunker , Kevin Mitchell , David Harris
发明人： Eva Bunker , Nelson Bunker , Kevin Mitchell , David Harris
IPC分类号： G06F21/56 , H04L29/06 , G06F21/57
CPC分类号： H04L63/20 , G06F21/577 , Y10S707/957 , Y10S707/959
摘要： A system for controlling selection of filters for protecting against vulnerabilities of a computer network includes a vulnerability management system analyzes the computer network and determines network vulnerabilities for the computer network. The vulnerability management system is configured to receive real-time data on a status of filters protecting against vulnerabilities of the computer network. A database contains a pre-generated mapping of network vulnerabilities to filters for protecting against the network vulnerabilities. The vulnerability management system enables user control of filters for protecting against vulnerabilities of the computer network based upon the determined network vulnerabilities of the computer network, the pre-generated mapping of network vulnerabilities to the filters for protecting against the network vulnerabilities and the real-time data on the status of the filters.
摘要翻译：用于控制用于防止计算机网络的漏洞的过滤器的选择的系统包括分析计算机网络并确定计算机网络的网络漏洞的漏洞管理系统。漏洞管理系统被配置为接收关于防止计算机网络的漏洞的过滤器的状态的实时数据。数据库包含预先生成的网络漏洞映射到过滤器以防止网络漏洞。该漏洞管理系统使得用户能够根据确定的计算机网络的网络漏洞来保护过滤器以防止计算机网络的漏洞，将预先生成的网络漏洞映射到过滤器以防止网络漏洞和实时有关过滤器状态的数据。

10. 发明申请

US20100124013A1 Laptop computer carrying case that transforms into a desk top 有权
标题翻译：笔记本电脑手提箱转换成桌面
公开(公告)号：US20100124013A1
公开(公告)日：2010-05-20
申请号：US12313065
申请日：2008-11-17
申请人： Kevin Mitchell
发明人： Kevin Mitchell
IPC分类号： H02B1/00
CPC分类号： G06F1/1628 , A45C3/02 , A45C9/00 , A45C2011/002 , A45C2013/025 , A45F3/02 , A45F3/12 , A45F5/00 , A45F2005/006 , A45F2200/0525
摘要： A laptop computer carrying case transforms into a desktop for use of a laptop or similar electronic device having a keyboard and a hingeably openable display. The laptop key board is held by bands in the lower portion of the case and the display is held in the top section of the case. Hinge structures are provided on the left and right sidewalls of the bottom section of the case. When the hinge structures are pivotally angularly separated, the bottom section containing the keyboard will be substantially horizontal enabling use of the laptop in a standing or mobile position. When the laptop is not being used, the case may be closed and the hinge structures closed with the laptop being carried by the strap over the shoulder. The hinge structure is provided with structure for limiting the amount by which the arms of the hinge may be pivotally angularly separated thereby providing stability to the laptop case in the desk top position. Detent means is provided to hold the arms of the hinge structure in aligned position when the case is being used to carry the laptop.
摘要翻译：膝上型计算机手提箱转换成桌面以用于具有键盘和可铰接地打开的显示器的笔记本电脑或类似的电子设备。笔记本电脑键盘由外壳的下部的带子保持，显示器被保持在外壳的顶部。铰链结构设置在壳体底部的左侧壁和右侧壁上。当铰链结构以角度方式分开时，包含键盘的底部部分将基本上是水平的，使得可以在站立或移动的位置使用笔记本电脑。当笔记本电脑没有被使用时，外壳可能会被关闭，并且铰链结构用膝上型计算机被肩带承载的关闭。铰链结构设置有用于限制铰链的臂可以以角度方式分开的量的结构，从而为桌面位置的膝上型计算机壳体提供稳定性。当壳体被用于携带膝上型计算机时，提供定位装置以将铰链结构的臂保持在对准位置。

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