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1. 发明申请

WO2013156415A1 DEVICE AND METHOD FOR THE NON-INVASIVE MEASUREMENT OF STATE OF TENSION, BIOMECHANICAL AND VISCOELASTIC PROPERTIES OF SURFACES OF SOFT BIOLOGICAL TISSUES 审中-公开
标题翻译：软生物组织表面非张力测量状态，生物体和粘弹性性质的装置和方法
公开(公告)号：WO2013156415A1
公开(公告)日：2013-10-24
申请号：PCT/EP2013/057732
申请日：2013-04-12
申请人： MYOTON AS
发明人： PEIPSI, Aleko
IPC分类号： A61B5/00 , G01N3/24 , G01N3/30
CPC分类号： A61B5/0051 , A61B5/442 , A61B9/00 , A61B2090/064 , B06B1/04 , G01N3/317 , G01N2203/0089 , G01N2203/0094
摘要： Device and method for the non-invasive measurement of state of tension, biomechanical and viscoelastic properties of surfaces of soft biological tissues A device (10) for measurement of biomechanical and viscoelastic properties of a surface (4) of a soft biological tissue with elastic properties includes a housing (1) comprising electronic, digital and mechanical elements and sensors, and also a testing end (2). The elements within the housing (1) can subject the testing end (2) to a mechanical impulse force (13), and can sense (15) the movement (A) of the testing end (2). The testing end (2) has a contact surface (5) which can be adhered (3) to the surface (4) of the soft biological tissue, and subjected to a mechanical force in a direction parallel to the surface (4).
摘要翻译：用于非侵入性测量软生物组织表面的张力状态，生物力学和粘弹性的装置和方法用于测量具有弹性性质的软生物组织表面（4）的生物力学和粘弹性性质的装置（10）包括包括电子，数字和机械元件和传感器的壳体（1），以及测试端（2）。壳体（1）内的元件可以使测试端（2）受到机械冲击力（13），并且可以感测（15）测试端（2）的运动（A）。测试端（2）具有接触表面（5），该接触表面可以粘附到软生物组织的表面（4）上，并且在平行于表面（4）的方向上受到机械力。

2. 发明申请

WO2014122011A1 SYSTEM AND METHOD FOR NON-INVASIVE MEASUREMENT OF SOFT BIOLOGICAL TISSUE 审中-公开
标题翻译：软生物组织非侵入性测量的系统和方法
公开(公告)号：WO2014122011A1
公开(公告)日：2014-08-14
申请号：PCT/EP2014/051154
申请日：2014-01-21
申请人： MYOTON AS
发明人： PEIPSI, Aleko
IPC分类号： A61B5/103 , G01N3/44
CPC分类号： A61B5/442 , A61B5/0053 , A61B5/4519 , A61B5/4523 , G01N3/42 , G01N2203/0089
摘要： A system (100) and method for the non-invasive measurement of tone, state of tension, biomechanical or viscoelastic properties of soft biological tissues (125) comprises a testing-end (1), an actuator (3) arranged to apply a force to the testing-end (1), and a sensor (2, 21) to sense movement of the testing-end (1). The system comprises a signal generating circuit (6, 10) to supply a control signal to the actuator (3) so the biological tissues are subjected by the testing-end (1) to a load, including means (5) to adjust the signal provided by the signal generating circuit (6, 10) in accordance with the component of weight acting through the testing-end (1) onto the biological tissue so that the load to which the biological tissue is subjected is constant. It also comprises an impulse signal generating circuit (7, 10) to supply an impulse signal to the actuator (3) so the biological tissue is subjected by the testing-end (1) to a mechanical deformation. In use the soft biological tissue is subjected first to the constant load, and then to the impulse signal; and the consequent movement of the biological tissue (125) is then registered.
摘要翻译：用于非侵入性测量软生物组织（125）的音调，张力状态，生物力学或粘弹性质的系统（100）和方法包括测试端（1），致动器（3），其布置成施加力到测试端（1）和用于感测测试端（1）的移动的传感器（2,21）。该系统包括一个向致动器（3）提供控制信号的信号发生电路（6,10），使得生物组织被测试端（1）经受负载，包括用于调节信号的装置（5）由信号发生电路（6,10）根据通过测试端（1）作用在生物组织上的重量分量提供，使得生物组织受到的负荷是恒定的。它还包括脉冲信号发生电路（7,10），以向致动器（3）提供脉冲信号，使得生物组织受到测试端（1）的机械变形。在使用中，软生物组织首先经受恒定负荷，然后进行脉冲信号; 然后记录生物组织（125）的随后移动。

3. 发明公开

EP2953539A1 SYSTEM AND METHOD FOR NON-INVASIVE MEASUREMENT OF SOFT BIOLOGICAL TISSUE 有权
标题翻译：系统VERFAHREN ZUR NICHTINVASIVEN MESSUNG VON WEICHEM生物学家GEWEBE
公开(公告)号：EP2953539A1
公开(公告)日：2015-12-16
申请号：EP14701951.7
申请日：2014-01-21
申请人： Myoton AS
发明人： PEIPSI, Aleko , SULLIN, Anti , LIIK, Mart
IPC分类号： A61B5/103 , G01N3/44
CPC分类号： A61B5/442 , A61B5/0053 , A61B5/4519 , A61B5/4523 , G01N3/42 , G01N2203/0089
摘要： A system (100) and method for the non-invasive measurement of tone, state of tension, biomechanical or viscoelastic properties of soft biological tissues (125) comprises a testing-end (1), an actuator (3) arranged to apply a force to the testing-end (1), and a sensor (2, 21) to sense movement of the testing-end (1). The system comprises a signal generating circuit (6, 10) to supply a control signal to the actuator (3) so the biological tissues are subjected by the testing-end (1) to a load, including means (5) to adjust the signal provided by the signal generating circuit (6, 10) in accordance with the component of weight acting through the testing-end (1) onto the biological tissue so that the load to which the biological tissue is subjected is constant. It also comprises an impulse signal generating circuit (7, 10) to supply an impulse signal to the actuator (3) so the biological tissue is subjected by the testing-end (1) to a mechanical deformation. In use the soft biological tissue is subjected first to the constant load, and then to the impulse signal; and the consequent movement of the biological tissue (125) is then registered.
摘要翻译：用于无创测量软生物组织的音调，张力状态，生物力学或粘弹性属性的系统和方法包括测试端，布置成向测试端施加力的致动器，以及用于感测运动的传感器的测试结束。信号发生电路向致动器提供控制信号，使得生物组织被测试端承载到负载，包括用于根据通过测试时的作用的重量分量来调整由信号发生电路提供的信号的装置，结束生物组织，使得生物组织受到的负荷是恒定的。脉冲信号发生电路将脉冲信号提供给致动器，使得生物组织受到测试端的机械变形。在使用中，软生物组织首先经受恒定负荷，然后进行脉冲信号; 然后记录生物组织的随后运动。

4. 发明授权

EP2953539B1 SYSTEM AND METHOD FOR NON-INVASIVE MEASUREMENT OF SOFT BIOLOGICAL TISSUE 有权
标题翻译：用于非侵入性测量软生物组织的系统和方法
公开(公告)号：EP2953539B1
公开(公告)日：2017-12-13
申请号：EP14701951.7
申请日：2014-01-21
申请人： Myoton AS
发明人： PEIPSI, Aleko , SULLIN, Anti , LIIK, Mart
IPC分类号： A61B5/103 , G01N3/44
CPC分类号： A61B5/442 , A61B5/0053 , A61B5/4519 , A61B5/4523 , G01N3/42 , G01N2203/0089

5. 发明授权

EP2658442B1 DEVICE FOR REAL-TIME MEASUREMENT OF PARAMETERS OF MECHANICAL STRESS STATE AND BIOMECHANICAL PROPERTIES OF SOFT BIOLOGICAL TISSUE 有权
标题翻译：用于实时测量软生物组织机械应力状态参数和生物力学性能的装置
公开(公告)号：EP2658442B1
公开(公告)日：2017-09-06
申请号：EP11749721.4
申请日：2011-07-07
申请人： Myoton AS
发明人： VAIN, Arved , PEIPSI, Aleko , LIIK, Mart
IPC分类号： A61B5/00 , G01D5/12 , G01D5/22
CPC分类号： A61B5/103 , A61B5/0051 , A61B5/0053 , A61B5/4519 , A61B9/00 , G01D5/2033 , H01F7/122 , H01F7/1615
摘要： A device and a method for simultaneous recording, in real time, parameters characterising the mechanical tension, elasticity, dynamical stiffness, creepability and mechanical stress of soft biological tissue are provided. By means of the myometer, a constant external pre-pressure is created, independently of the device's position, between the tissue and the testing end of the device. Next, the tissue is subjected to a short-term external dynamic influence. A mechanical change in the shape of the tissue and its mechanical response are registered as a graph of the tissue's oscillations. For calculating the parameters, a time span on the graph is used which involves an oscillation period from the beginning to the end of the effect on the tissue plus its subsequent first 1.5 self-oscillation period. This enables recording and data-processing to be carried out simultaneously as well as statistically significant estimates to be made in real time.
摘要翻译：提供了用于实时同时记录表征软生物组织的机械张力，弹性，动态刚度，可蠕变性和机械应力的参数的装置和方法。通过肌计，在组织和设备的测试端之间产生恒定的外部预压，与设备的位置无关。接下来，组织受到短期外部动态影响。组织形状的机械变化及其机械响应被记录为组织振荡的图形。为了计算参数，使用图上的时间跨度，其涉及从组织的影响从开始到结束的振荡周期加上其随后的第一个1.5自振周期。这使得记录和数据处理可以同时进行，并且可以实时进行统计显着的估计。

6. 发明公开

EP2838417A1 DEVICE AND METHOD FOR THE NON-INVASIVE MEASUREMENT OF STATE OF TENSION, BIOMECHANICAL AND VISCOELASTIC PROPERTIES OF SURFACES OF SOFT BIOLOGICAL TISSUES 有权
标题翻译： DEVICE AND METHOD FOR A国地位的非侵入式测量和生物软组织表面的生物力学和粘弹性特性
公开(公告)号：EP2838417A1
公开(公告)日：2015-02-25
申请号：EP13716287.1
申请日：2013-04-12
申请人： Myoton AS
发明人： PEIPSI, Aleko
IPC分类号： A61B5/00 , G01N3/24 , G01N3/30
CPC分类号： A61B5/0051 , A61B5/442 , A61B9/00 , A61B2090/064 , B06B1/04 , G01N3/317 , G01N2203/0089 , G01N2203/0094
摘要： A device and method for the non-invasive measurement of state of tension, biomechanical and viscoelastic properties of surfaces of soft biological tissues includes electronic, digital and mechanical elements and sensors, and a testing end. The elements within the housing can subject the testing end to a mechanical impulse force, and can sense the movement of the testing end. The testing end has a contact surface which can be adhered to the surface of the soft biological tissue, and subjected to a mechanical force in a direction parallel to the surface.

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