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1. 发明申请

WO2018014030A1 MULTI-COMPARTMENT CAPSULE 审中-公开
标题翻译：多分区胶囊
公开(公告)号：WO2018014030A1
公开(公告)日：2018-01-18
申请号：PCT/US2017/042430
申请日：2017-07-17
申请人： MULTIPLY LABS INC.
发明人： PARIETTI, Federico , MELOCCHI, Alice , ZEMA, Lucia , GAZZANIGA, Andrea
IPC分类号： A61K9/48 , A61K9/52 , A61K9/14 , A61K45/06
摘要： A method of making a capsule comprising a plurality of compartments, the method comprising: initiating extrusion of a filament solution through a filament extruder; laying the filament solution to form a base of the capsule; forming a first compartment in the plurality of compartments, wherein the forming creates a first barrier wall having a first predetermined release time; forming a second compartment in the plurality of compartments, wherein the forming creates a second barrier wall having a second predetermined release time; filling the first compartment with a first material; filling the second compartment with a second material; and sealing the plurality of compartments thereby forming the capsule with a first sealed compartment and a second sealed compartment.
摘要翻译：一种制造包含多个隔室的胶囊的方法，所述方法包括：开始通过长丝挤出机挤出长丝溶液; 铺设细丝溶液以形成胶囊的基部; 在所述多个隔室中形成第一隔室，其中所述形成形成具有第一预定释放时间的第一隔壁; 在所述多个隔室中形成第二隔室，其中所述形成形成具有第二预定释放时间的第二隔壁; 用第一材料填充第一隔室; 用第二种材料填充第二隔室; 并密封多个隔室，从而形成具有第一密封隔室和第二密封隔室的胶囊。

2. 发明申请

WO2018232411A1 SYSTEMS AND METHODS FOR DESIGNING AND MANUFACTURING MULTI-COMPARTMENT CAPSULES 审中-公开
公开(公告)号：WO2018232411A1
公开(公告)日：2018-12-20
申请号：PCT/US2018/038114
申请日：2018-06-18
申请人： MULTIPLY LABS INC.
发明人： PARIETTI, Federico , CHAN, Kameron, C. , BRIGHT, Lawrence, Zachary , CURHAN, Jeffrey, Ackerman , MELOCCHI, Alice , ZEMA, Lucia , GAZZANIGA, Andrea , WILSON, Joseph, Siener , KUO, Tiffany, Amy , SHARMA, Vaibhav , RUTTER, Andrew
IPC分类号： B29C64/118 , B33Y30/00
CPC分类号： B29C64/209 , A61K9/48 , A61K9/4808 , A61K9/4833 , B01J13/04 , B29C64/118 , B33Y30/00
摘要： A dispensing system includes a filament extruder that lays filament solutions. The filament extruder comprises multiple extruder sets. Each extruder set includes a first and a second extruder. Each of the first and the second extruder includes an extruder portion, a hot end portion, and a shroud. The extruder portion includes a first and a second insert that combine to form a channel and a needle tube that receives the filament solution from the channel and lays the filament solution on the target surface.

3. 发明申请

WO2021168368A1 SYSTEMS AND METHODS FOR FACILITATING MODULAR AND PARALLELIZED MANUFACTURING AT A BIOLOGICAL FOUNDRY 审中-公开
公开(公告)号：WO2021168368A1
公开(公告)日：2021-08-26
申请号：PCT/US2021/018927
申请日：2021-02-19
申请人： MULTIPLY LABS, INC.
发明人： PARIETTI, Federico , CHAN, Kameron, C. , MELOCCHI, Alice , CURHAN, Jeffrey Ackerman , CHEN, Michelle , DICKEY, Nolan , GIRALDO-LAGUNA, Joaquin , LO, Roger , BRIGHT, Lawrence, Zachary
IPC分类号： G16B50/00 , G05B19/418 , G06F9/38
摘要： Systems and methods for implementing one or more compiled workflows at a biological foundry are provided. A representation of an uncompiled workflow to produce engineering targets is obtained. The representation is translated into a first corresponding instance of a compiled workflow. If the translation satisfaction of various threshold translation criteria is determined, and the first corresponding instance of the compiled workflow is executed to complete a first portion of manufacture of the engineering targets. If the executing satisfaction of various threshold execution criteria is determined, the representation is translated into a second corresponding instance of the compiled workflow different from the first corresponding instance. If this translation satisfaction of the various threshold translation criteria is determined, the second corresponding instance of the compiled workflow is executed to complete a second portion of the manufacture of the engineering targets.

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