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1. 发明专利

JP2014184317A System, device, method and procedure for noninvasive tissue treatment using microwave energy 有权
标题翻译：使用微波能量的非感染组织治疗的系统，装置，方法和程序
公开(公告)号：JP2014184317A
公开(公告)日：2014-10-02
申请号：JP2014095998
申请日：2014-05-07
申请人： Miramar Labs Inc , ミラマーラブズ, インコーポレイテッド
发明人： JESSI ERNEST JOHNSON , DEEM MARK E , DANIEL FRANCIS , KIM STEVEN , ALEXEY SALAMINI , SU TED , PETER SMITH , DANIEL HALLOCK , YOAV BEN-HAIM , SHAILENDHAR SARAF
IPC分类号： A61N5/04
摘要： PROBLEM TO BE SOLVED: To provide a system, a device, a method and a procedure, for noninvasive tissue treatment using microwave energy.SOLUTION: A system, a device and a method for noninvasive treatment of a tissue, use microwave energy. In one embodiment of the present invention, a medical device, a related device and a procedure are used so as to treat a skin symptom by use of the microwave energy. For example, the device is a disposable medical device, and includes: a tissue chamber disposed in a distal end of a disposable member; an applicator chamber disposed in a proximal end of the disposable member; a tissue biological barrier separating an interface between the tissue chamber and an applicator; and a vacuum circuit connecting the tissue chamber and the applicator chamber.
摘要翻译：要解决的问题：提供用于使用微波能量的无创组织处理的系统，装置，方法和程序。解决方案：用于非侵入性处理组织的系统，装置和方法，使用微波能量。在本发明的一个实施例中，使用医疗装置，相关装置和程序，以便通过使用微波能量来治疗皮肤症状。例如，该装置是一次性医疗装置，并且包括：设置在一次性构件的远端中的组织室; 设置在所述一次性构件的近端中的施用器室; 组织生物屏障，其分离所述组织室和施用器之间的界面; 以及连接组织室和施用器室的真空回路。

2. 发明专利

JP2014184319A System and method for causing effect in specific tissue by use of microwave energy 有权
标题翻译：通过使用微波能量引起特定组织中的影响的系统和方法
公开(公告)号：JP2014184319A
公开(公告)日：2014-10-02
申请号：JP2014096614
申请日：2014-05-08
申请人： Miramar Labs Inc , ミラマーラブズ, インコーポレイテッド
发明人： DEEM MARK E , FRANCIS DAN , JESSI ERNEST JOHNSON , KIM STEVEN , SALAMINI ALEXEY , SU TED , PETER SMITH , DAN HALLOCK
IPC分类号： A61N5/04 , A61B18/18
CPC分类号： A61B18/1815 , A61B18/18 , A61B90/37 , A61B2018/00005 , A61B2018/00023 , A61B2018/00029 , A61B2018/00041 , A61B2018/00291 , A61F2007/0075 , A61N5/02
摘要： PROBLEM TO BE SOLVED: To provide a system and a method for causing effect in a specific tissue by use of microwave energy.SOLUTION: According to some embodiments, a system for applying microwave energy to a tissue can include: a signal generator fit to generate a microwave signal having a prescribed characteristic; an applicator which is connected to the generator, is fit to apply the microwave energy to the tissue, and includes one or more microwave antennas and a tissue interface; a decompression source connected to the tissue interface; a refrigerant source connected to the tissue interface; and a controller fit to control the signal generator, the decompression source, and the refrigerant source. The controller is configured such that the system delivers the energy so as to generate a peak power loss density profile in a second layer present below a first layer of the tissue.
摘要翻译：要解决的问题：提供通过使用微波能量在特定组织中产生效果的系统和方法。解决方案：根据一些实施例，用于向组织施加微波能量的系统可以包括：适合产生具有规定特性的微波信号; 连接到发生器的施加器适于将微波能量施加到组织，并且包括一个或多个微波天线和组织界面; 连接到组织界面的减压源; 连接到组织界面的制冷剂源; 以及适于控制信号发生器，减压源和制冷剂源的控制器。控制器被配置为使得系统传送能量，以便在存在于组织的第一层下方的第二层中产生峰值功率损耗密度分布。

3. 发明专利

JP2014014721A System, apparatus, method, and procedure for noninvasive treatment of tissue using microwave energy 有权
标题翻译：用微波能量组织非治疗性治疗的系统，装置，方法和程序
公开(公告)号：JP2014014721A
公开(公告)日：2014-01-30
申请号：JP2013222012
申请日：2013-10-25
申请人： Miramar Labs Inc , ミラマーラブズ, インコーポレイテッド
发明人： KIM STEVEN , DANIEL FRANCIS , JESSI E JOHNSON , ALEXEY SALAMINI , SU TED , DONG HOON CHAN , YOAV BEN-HAIM
IPC分类号： A61B18/18
摘要： PROBLEM TO BE SOLVED: To provide systems, apparatuses, methods and procedures for noninvasive treatment of tissue using microwave energy.SOLUTION: The present invention is directed to systems, apparatuses, methods and procedures for the noninvasive treatment of tissue using microwave energy. In one embodiment of the invention, a medical device and associated apparatus and procedures are used, for example, to treat dermatological conditions using microwave energy. The present application relates to methods, apparatuses and systems for non-invasively delivering energy, such as, for example, microwave energy, to the epidermal, dermal and sub-dermal tissue of a patient to achieve various therapeutic results and/or aesthetic results.
摘要翻译：要解决的问题：提供使用微波能量对组织进行无创处理的系统，装置，方法和程序。解决方案：本发明涉及使用微波能量对组织进行无创处理的系统，装置，方法和程序。在本发明的一个实施例中，使用医疗装置和相关联的装置和程序，例如，使用微波能量治疗皮肤病学病症。本申请涉及用于非侵入性地将能量（例如微波能量）递送到患者的表皮，皮肤和皮下组织以实现各种治疗结果和/或美学结果的方法，装置和系统。

4. 发明专利

BRPI0810066A2 Sistemas e métodos para criação de um efeito utilizando energia de microondas à tecido específico 未知
公开(公告)号：BRPI0810066A2
公开(公告)日：2015-05-05
申请号：BRPI0810066
申请日：2008-04-18
申请人： THE FOUNDRY INC , MIRAMAR LABS INC
发明人： DEEM MARK E , FRANCIS DAN , JOHNSON JESSI ERNEST , KIM STEVEN , SALAMINI ALEXEY , SU TED , SMITH PETER , HALLOCK DAN
IPC分类号： A61B18/18

5. 发明专利

SG186642A1 SYSTEMS, APPARATUS, METHODS AND PROCEDURES FOR THE NONINVASIVE TREATMENT OF TISSUE USING MICROWAVE ENERGY 未知
公开(公告)号：SG186642A1
公开(公告)日：2013-01-30
申请号：SG2012090429
申请日：2008-12-12
申请人： MIRAMAR LABS INC
发明人： JOHNSON JESSI ERNEST , DEEM MARK E , FRANCIS DANIEL , KIM STEVEN , SALAMINI ALEXEY , SU TED , SMITH PETER , HALLOCK DANIEL , BEN-HAIM YOAV , SARAF SHAILENDHAR
摘要： - 123 -SYSTEMS, APPARATUS, METHODS AND PROCEDURES FOR THE NONINVASIVE TREATMENT OF TISSUE USING MICROWAVE ENERGYAbstractThe present invention is directed to systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy. In one embodiment of the invention a medical device and associated apparatus and procedures are used to treat dermatological conditions using microwave energy.Figure 1

6. 发明申请

WO2009075879A8 SYSTEMS, APPARATUS, METHODS AND PROCEDURES FOR THE NONINVASIVE TREATMENT OF TISSUE USING MICROWAVE ENERGY 审中-公开
标题翻译：使用微波能量的组织非侵袭性治疗的系统，装置，方法和程序
公开(公告)号：WO2009075879A8
公开(公告)日：2010-07-22
申请号：PCT/US2008013650
申请日：2008-12-12
申请人： MIRAMAR LABS INC , THE FOUNDRY INC , JOHNSON JESSI ERNEST , DEEM MARK E , FRANCIS DANIEL , KIM STEVEN , SALAMINI ALEXEY , SU TED , SMITH PETER , HALLOCK DANIEL , BEN-HAIM YOAV , SARAF SHAILENDHAR
发明人： JOHNSON JESSI ERNEST , DEEM MARK E , FRANCIS DANIEL , KIM STEVEN , SALAMINI ALEXEY , SU TED , SMITH PETER , HALLOCK DANIEL , BEN-HAIM YOAV , SARAF SHAILENDHAR
IPC分类号： A61N5/02
CPC分类号： A61B18/1815 , A61B18/02 , A61B18/14 , A61B18/18 , A61B18/20 , A61B2017/00106 , A61B2018/00023 , A61B2018/00291 , A61F2007/0075 , A61N7/02 , A61N2007/0008
摘要： The present invention is directed to systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy. In one embodiment of the invention a medical device and associated apparatus and procedures are used to treat dermatological conditions using microwave energy.
摘要翻译：本发明涉及使用微波能量对组织进行非侵入性处理的系统，装置，方法和程序。在本发明的一个实施例中，使用医疗装置和相关联的装置和程序来使用微波能量来治疗皮肤病学条件。

7. 发明申请

WO2015013502A3 APPARATUS AND METHODS FOR THE TREATMENT OF TISSUE USING MICROWAVE ENERGY 审中-公开
标题翻译：用微波能治疗组织的装置和方法
公开(公告)号：WO2015013502A3
公开(公告)日：2015-11-26
申请号：PCT/US2014047996
申请日：2014-07-24
申请人： MIRAMAR LABS INC
发明人： KIM STEVEN , SU TED , FRANCIS DANIEL , JOHNSON JESSI ERNEST , CHUN DONGHOON
IPC分类号： A61N5/02
CPC分类号： A61B18/1815 , A61B2018/00452 , A61N5/04
摘要： Systems and methods for delivering microwave energy to skin are provided, such that a focal zone of destructive heat is generated in the upper sub-dermis, mid-dermis, and/or lower dermis. This microwave therapy may be used for hair removal, treatment of acne, skin tightening, treatment of toe nail fungus, or sweat reduction. According to one embodiment, a system can include a microwave applicator having a distal treatment portion that includes at least one microwave antenna, a cooling system, and vacuum features. In some embodiments, the interaction between incident waves transmitted from the microwave applicator and reflected waves may be used to generate a standing wave with a peak energy density in selected regions of the dermis.
摘要翻译：提供用于将微波能量递送到皮肤的系统和方法，使得在上部真皮下，中部真皮和/或下部真皮中产生破坏性热的聚焦区。这种微波疗法可用于脱毛，治疗痤疮，紧致皮肤，治疗脚趾甲真菌或减少汗水。根据一个实施例，一种系统可以包括具有远端处理部分的微波施加器，所述远端处理部分包括至少一个微波天线，冷却系统和真空特征。在一些实施例中，从微波施加器发射的入射波与反射波之间的相互作用可用于在真皮的选定区域中产生具有峰值能量密度的驻波。

8. 发明申请

WO2010096840A3 TISSUE INTERFACE SYSTEM AND METHOD 审中-公开
标题翻译：组织界面系统和方法
公开(公告)号：WO2010096840A3
公开(公告)日：2011-01-20
申请号：PCT/US2010025124
申请日：2010-02-23
申请人： MIRAMAR LABS INC , KIM STEVEN , FRANCIS DANIEL , JOHNSON JESSI E , SALAMINI ALEXEY , SU TED , CHUNG DONG HOON , BEN-HAIM YOAV , LOEW CHRISTOPHER
发明人： KIM STEVEN , FRANCIS DANIEL , JOHNSON JESSI E , SALAMINI ALEXEY , SU TED , CHUNG DONG HOON , BEN-HAIM YOAV , LOEW CHRISTOPHER
IPC分类号： A61H7/00 , A61B5/00 , A61B5/04 , A61B5/05 , A61M1/00
CPC分类号： A61B18/18 , A61B18/1815 , A61B90/98 , A61B2017/306 , A61B2018/00005 , A61B2090/3937 , A61H9/0057 , A61H2201/10 , A61H2201/1685 , A61N5/02 , A61N5/04
摘要： An applicator-tissue interface is disclosed for use in connection with medical device treatment applicators. The interface provides a cover to protect applicator components against contamination and may be disposable or reusable. Also included are tissue acquisition features including a tissue receiving chamber defined by a bio-barrier with vacuum ports or channels for tissue acquisition. Vacuum balancing is provided to prevent contamination on the applicator side of the bio-barrier. Locking mechanisms are disclosed for ensuring secure attachment between the interface and applicator. Methods of using the applicator-tissue interface in connection with an applicator are also disclosed.
摘要翻译：公开了一种与医疗器械治疗敷料器结合使用的涂抹器 - 组织界面。界面提供了一个保护涂料组件免受污染的盖子，可以是一次性的或可重复使用的。还包括组织采集特征，包括由具有用于组织采集的真空端口或通道的生物屏障限定的组织接收室。提供真空平衡以防止生物屏障的施用器侧的污染。公开了锁定机构以确保接口和施加器之间的牢固连接。还公开了与施用器相关地使用施用器 - 组织界面的方法。

9. 发明专利

CA2842797C APPLICATOR AND TISSUE INTERFACE MODULE FOR DERMATOLOGICAL DEVICE 未知
公开(公告)号：CA2842797C
公开(公告)日：2019-09-24
申请号：CA2842797
申请日：2012-07-31
申请人： MIRAMAR LABS INC
发明人： BEN-HAIM YOAV , BENTLEY PETER J , CHUN DONG HOON , FRANCIS DANIEL , JOHNSON JESSI E , SHAN KEVIN , SU TED , KIM STEVEN
IPC分类号： A61B18/18 , A61N5/02
摘要： A dermatological energy applicator and tissue interface module are provided which may include any number of features. The dermatological energy applicator can be configured to apply microwave energy to tissue to treat conditions of the skin, including hyperhidrosis or excessive sweating. The energy applicator can further include a cooling element and vacuum ports. The tissue interface module can include an applicator chamber adapted to receive the energy applicator, and can further include a tissue acquisition chamber adapted to engage tissue, a bio-barrier configured to prevent passage of gas and liquid, and a filter disposed between the applicator chamber and the tissue acquisition chamber configured to prevent passage of gas but prevent passage of liquid.

10. 发明专利

CA2741109C SYSTEMS, APPARATUS, METHODS, AND PROCEDURES FOR THE NON-INVASIVE TREATMENT OF TISSUE USING MICROWAVE ENERGY 未知
公开(公告)号：CA2741109C
公开(公告)日：2019-05-21
申请号：CA2741109
申请日：2009-10-22
申请人： MIRAMAR LABS INC
发明人： KIM STEVEN , FRANCIS DANIEL , JOHNSON JESSI E , SALAMINI ALEXEY , SU TED , CHUN DONG HOON , BEN-HAIM YOAV , LOEW CHRISTOPHER , KOPELOW LEO , CHEW SUNMI
IPC分类号： A61N5/02 , A61B18/18
摘要： A system applies, in a non- invasive manner, energy to a targeted tissue region employing a controlled source of energy, a multiple use applicator, and a single use, applicator- tissue interface carried by the applicator. The system can generate and apply energy in a controlled fashion to form a predefined pattern of lesions that provide therapeutic benefit, e.g., to moderate or interrupt function of the sweat glands in the underarm (axilla).

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