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    • 1. 发明申请
    • SUPPORT ELEMENT FOR USE IN THE ANALYSIS OF SUBSTANCES
    • 支撑元件用于物质的分析
    • WO2005019818A3
    • 2005-06-02
    • PCT/EP2004009301
    • 2004-08-19
    • MICRONAS GMBHLEHMANN MIRKOSIEBEN ULRICH
    • LEHMANN MIRKOSIEBEN ULRICH
    • B01L3/00C40B70/00G01N31/22G01N33/50G01N33/543G06F19/20G06K7/10G06K19/06
    • G01N33/543B01J2219/00542B01J2219/00547B01J2219/00554B01J2219/00659B01L3/545B01L2300/021B01L2300/0819C40B70/00G06F19/20G06K19/06037
    • The invention relates to a support element (10, 20, 30, 30') for use in the analysis of substances to be analyzed to which, in at least two defined areas (11, 21, 31, 31'), biological and/or chemical substances (A to I) are applied and which comprises a code (12, 32, 32') indicating which biological and/or chemical substance (A to I) is present in which of the defined areas (11, 21, 31, 31'). The invention also relates to a method for producing support elements. The invention further relates to a device for reading out a support element by means of at least one optical detector per defined area (31) on the support element (30), whereby the optical detectors detect the reactions of the biological and/or chemical substances (A to I) in the defined areas (31) to the substance to be analyzed in the form of signals once the support element (30) is brought into a reading position relative to the device (50). The invention finally relates to a method for reading out a support element by means of a device for reading out a support element.
    • 本发明涉及一种支撑元件(10,20,30,30“),用于将物质的分析待分析在其上的至少两个区域(11,21,31,31”限定)生物和/或化学物质(A至I) 被施加,具有代码(12,32,32 '),指示哪个生物和/或化学物质(a至I),其中,限定的区域(11,21,31,31')的位置。 本发明还涉及一种用于支撑元件的制造方法。 本发明还涉及一种用于承载元件(30),每个定义的区域(31)读出的载体元件具有至少一个光学检测器,其中光学检测器,生物和/或化学物质的反应(A至I)中的定义的范围 检测(31)的物质,以尽快承载元件(30)被引入到相对于装置(50)和读取的支撑构件的方法的读取位置分析为信号。
    • 6. 发明申请
    • DEVICE FOR MEASURING PHYSIOLOGICAL PARAMETERS
    • 用于测量生理参数的装置
    • WO9928037A8
    • 1999-09-02
    • PCT/EP9807598
    • 1998-11-25
    • MICRONAS INTERMETALL GMBHWOLF BERNHARDSIEBEN ULRICH
    • WOLF BERNHARDSIEBEN ULRICH
    • G01N33/48B01L3/00C12M1/34G01N27/414G01N33/487G01N35/02
    • G01N33/48728B01L3/5027B01L3/508B01L2200/025B01L2300/0636B01L2300/0645B01L2300/0822Y10S435/808
    • The invention relates to a device (1) for measuring physiological parameters having a testing chamber (2) which is bordered by a first semiconductor chip (3) and a second semiconductor chip (4). A seal (7) which bounds the testing chamber (2) is arranged as a spacer between said semiconductor chips. The first semiconductor chip (3) has an active side which faces the testing chamber (2) and comprises the planar sensors. Biological cells located in a nutrient medium can be adherently attached on said active side in order to directly measure physiological parameters of the cells (6). The second semiconductor chip (4) comprises at least one addition sensor situated on an active side which faces the testing chamber (2) in order to measure global physiological parameters. The semiconductor chips (3, 4) are held in a sealing position by means of a holding device (8) which externally overlaps said chips. Outside the testing chamber (2), the semiconductor chips (3, 4) each comprise electrical connection contacts (2) which contact counter-contacts of the holding device. The invention is constructed in a simple and economical manner.
    • 一种用于测量生理参数的装置(1)具有测试室(2)由第一半导体芯片(3)和第二半导体芯片(4)被该边界作为间隔物的测试室(2)密封件之间限定 (7)被安排。 在第一半导体芯片(3)具有(2)的面向测试室,其具有有源侧平面传感器在其上位于在营养培养基中的生物细胞(6)的贴壁anlagerbar测量生理参数直接在细胞(6)。 第二半导体芯片(4)具有至少一个附加传感器,用于测量面向测试室(2)的有效侧上的全局生理参数。 半导体芯片(3,4)通过与外部重叠的支架(8)保持在密封位置。 在测试室(2)的外部,半导体芯片(3,4)各自具有电连接触点,所述电连接触点使保持器与配合触点接触。 该设备简单且便宜。
    • 7. 发明申请
    • TEST STRIP AND METHOD FOR MEASURING AN ANALYTE CONCENTRATION IN A SAMPLE OF A BIOLOGICAL FLUID
    • 用于测量生物流体样品中分析浓度的测试条和方法
    • WO2007079843A3
    • 2007-09-13
    • PCT/EP2006011662
    • 2006-12-05
    • MICRONAS HOLDING GMBHKLAPPROTH HOLGERSIEBEN ULRICHYEE KEEN
    • KLAPPROTH HOLGERSIEBEN ULRICHYEE KEEN
    • G01N21/86H04M1/725
    • G01N21/8483G01N21/272G01N2021/8488
    • Disclosed is a method for measuring a concentration of an analyte contained in a sample of a biological fluid. In said method, a test strip (1) is provided which comprises at least one test point and at least one reference color section encompassing the color white and/or a color scale. The fluid sample is brought in contact with the test point, and a color indicator is disposed on the test point in accordance with the concentration of the analyte. A camera (8) is placed on the test strip (1). At least one measured value is detected for the relative position between the camera (8) and the test strip (1) and is compared to a set value range. If the measured value deviates from the set value range, the camera (8) is moved relative to the test strip (1) to reduce the deviation. A colored image on which at least the color indicator (3) and the reference color section (4) are represented is detected with the aid of the camera (8). The image areas assigned to the color indicator (3) and the color matching section (4) are located, and the color values of said image areas are determined. The analyte concentration in the sample is determined based on the color values with the aid of predefined comparative values.
    • 在用于测量包含在生物流体的样品中的分析物的浓度的方法中,测试条(1)提供了具有至少一个测试位点和至少一种颜色的白色和/或彩色标度全面的参考色区域。 流体样品被带入与测试位点接触,并且根据所述分析物的浓度,颜色指示器被布置在测试位点。 照相机(8)位于测试条(1)上。 用于摄像机(8)和测试条(1)之间的相对位置被检测到的至少一个测量值和与目标值范围进行比较。 当相对于所述测试条(1)的偏差减小的测量值和目标值之间的范围内的偏差,照相机(8)被移动。 借助照相机(8),至少记录颜色指示器(3)和参考颜色区域(4)的彩色图像被记录。 定位与颜色指示器(3)和颜色平衡区域(4)相关联的图像区域并确定这些图像区域的颜色值。 基于颜色值,借助于预定的比较值确定样品中的分析物浓度。