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1. 发明申请

WO2010138343A1 NEUROMEDIN U RECEPTOR AGONISTS 审中-公开
标题翻译： NEUROMEDIN U受体激素
公开(公告)号：WO2010138343A1
公开(公告)日：2010-12-02
申请号：PCT/US2010/035260
申请日：2010-05-18
申请人： MERCK SHARP & DOHME CORP. , ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA , PESSI, Antonello , BIANCHI, Elisabetta , INGALLINELLA, Paolo , LAHM, Armin , NEUNER, Philippe , TALAMO, Fabio , BARBATO, Gaetano , MARSH, Donald, J. , PEIER, Andrea
发明人： PESSI, Antonello , BIANCHI, Elisabetta , INGALLINELLA, Paolo , LAHM, Armin , NEUNER, Philippe , TALAMO, Fabio , BARBATO, Gaetano , MARSH, Donald, J. , PEIER, Andrea
IPC分类号： A61K38/00
CPC分类号： A61K38/22 , A61K47/643 , A61K47/6835
摘要： Neuromedin U receptor agonists comprising neuromedin U or derivative or analog thereof conjugated to a carrier protein for use in the treatment of metabolic disorders such as obesity and diabetes are disclosed.
摘要翻译：公开了包含神经介肽U或其与载体蛋白缀合的衍生物或类似物用于治疗代谢性疾病如肥胖症和糖尿病的神经介肽U受体激动剂。

2. 发明公开

EP3097180A1 DEVICE FOR ULTRASOUND TESTS 有权
标题翻译：设备技术超声波检查
公开(公告)号：EP3097180A1
公开(公告)日：2016-11-30
申请号：EP15707791.8
申请日：2015-01-20
申请人： Promedica Bioelectronics S.r.l. , Barbato, Gaetano , Image Guided Therapy SA
发明人： BARBATO, Gaetano , CATALLO, Nadia , CORSO, Cristiano , SCOARUGHI, Gian Luca , DUMONT, Erik
IPC分类号： C12M1/42 , A61K41/00 , G01N29/22
CPC分类号： G01N29/27 , C12M35/04 , G01N29/222 , G01N29/346 , G01N29/348 , G01N33/4833 , G01N2291/02466
摘要： A device (1) for ultrasound tests, comprising one or more transducers (4) for generating ultrasound beams with different powers and/or frequencies to be projected in direction of a plurality of targets (11), guaranteeing the separate control of the temperature both of the targets and of the transducers and it allows performing several tests contemporarily, by optimizing the functionality and the efficiency of the device, at the same time by guaranteeing results comparable therebetween for each test, and to this purpose it comprises: a first supporting structure (3) having at least a closed chamber (7; 23) receiving the body of said one or more transducers (4) and it is isolated from a propagation liquid medium, by leaving exposed each respective vibrating surface in contact with said liquid medium at a prefixed distance from the respective targets (11), the closed chamber containing a thermorefrigerating fluid in contact with the body of said one or more transducers; a second supporting structure (10) for said targets (11); means for refrigerating, through said thermorefrigerating fluid, the body of said one or more transducers (4); and means for keeping the liquid medium, which dampens said targets (11), at a predetermined temperature.

3. 发明申请

WO2015110955A1 DEVICE FOR ULTRASOUND TESTS 审中-公开
标题翻译：用于超声测试的设备
公开(公告)号：WO2015110955A1
公开(公告)日：2015-07-30
申请号：PCT/IB2015/050434
申请日：2015-01-20
申请人： PROMEDICA BIOELECTRONICS S.R.L. , BARBATO, Gaetano , IMAGE GUIDED THERAPY SA
发明人： BARBATO, Gaetano , CATALLO, Nadia , CORSO, Cristiano , SCOARUGHI, Gian Luca , DUMONT, Erik
IPC分类号： C12M1/42 , A61K41/00 , G01N29/22
CPC分类号： G01N29/27 , C12M35/04 , G01N29/222 , G01N29/346 , G01N29/348 , G01N33/4833 , G01N2291/02466
摘要： A device (1) for ultrasound tests, comprising one or more transducers (4) for generating ultrasound beams with different powers and/or frequencies to be projected in direction of a plurality of targets (11), guaranteeing the separate control of the temperature both of the targets and of the transducers and it allows performing several tests contemporarily, by optimizing the functionality and the efficiency of the device, at the same time by guaranteeing results comparable therebetween for each test, and to this purpose it comprises: a first supporting structure (3) having at least a closed chamber (7; 23) receiving the body of said one or more transducers (4) and it is isolated from a propagation liquid medium, by leaving exposed each respective vibrating surface in contact with said liquid medium at a prefixed distance from the respective targets (11), the closed chamber containing a thermorefrigerating fluid in contact with the body of said one or more transducers; a second supporting structure (10) for said targets (11); means for refrigerating, through said thermorefrigerating fluid, the body of said one or more transducers (4); and means for keeping the liquid medium, which dampens said targets (11), at a predetermined temperature.
摘要翻译： 1.一种用于超声波测试的装置（1），包括用于产生具有不同功率和/或频率的超声波束的多个换能器（4），以在多个目标（11）的方向上投射，保证了两者的温度的单独控制的目标和传感器，并且它允许通过优化设备的功能和效率同时执行几个测试，同时通过保证每个测试的可比性，并且为此目的，它包括：第一支撑结构（3）至少具有接收所述一个或多个换能器（4）的主体的封闭腔（7; 23），并且通过使每个相应的振动表面与所述液体介质接触而将其与传播液体介质隔离距离各个目标（11）的预定距离，所述封闭室包含与所述一个或多个换能器的主体接触的热致冷流体; 用于所述目标（11）的第二支撑结构（10）; 用于通过所述制冷剂流体冷却所述一个或多个换能器（4）的主体的装置; 以及用于保持将所述目标（11）抑制在预定温度的液体介质的装置。

4. 发明公开

EP3732476A1 ULTRASOUND TEST METHOD, AND RELATED TEST DEVICE AND WELL PLATE 审中-公开
公开(公告)号：EP3732476A1
公开(公告)日：2020-11-04
申请号：EP18796771.6
申请日：2018-10-15
申请人： Barbato, Gaetano
发明人： BARBATO, Gaetano , SCOARUGHI, Gian Luca , CORSO, Cristiano
IPC分类号： G01N29/02 , B01J19/10 , B01L3/00 , G01N29/22 , G01N29/27 , G01N29/28 , G01N29/32

5. 发明公开

EP3732475A1 ULTRASOUND TEST METHOD, AND RELATED TEST DEVICE AND WELL PLATE 审中-公开
公开(公告)号：EP3732475A1
公开(公告)日：2020-11-04
申请号：EP18796770.8
申请日：2018-10-15
申请人： Barbato, Gaetano
发明人： BARBATO, Gaetano , SCOARUGHI, Gian Luca , CORSO, Cristiano
IPC分类号： G01N29/02 , B01J19/10 , G01N29/22 , G01N29/27 , G01N29/28 , G01N29/32 , B01L3/00

6. 发明申请

WO2019077465A1 ULTRASOUND TEST METHOD, AND RELATED TEST DEVICE AND WELL PLATE 审中-公开
公开(公告)号：WO2019077465A1
公开(公告)日：2019-04-25
申请号：PCT/IB2018/057966
申请日：2018-10-15
申请人： PROMEDICA BIOELECTRONICS S.R.L. , BARBATO, Gaetano
发明人： BARBATO, Gaetano , SCOARUGHI, Gian Luca , CORSO, Cristiano
IPC分类号： G01N29/02 , B01J19/10 , B01L3/00 , G01N29/22 , G01N29/27 , G01N29/28 , G01N29/32
CPC分类号： G01N29/222 , B01L3/5085 , B01L2200/12 , B01L2300/0829 , B01L2300/123 , G01N29/02 , G01N29/27 , G01N29/28 , G01N29/32 , G01N2291/02466 , G01N2291/106
摘要： In a method for performing ultrasound tests which uses a suitable device for performing such tests, a well plate (11) implements a perfect insulation between the different wells (21) of the well plate (21) of such set, without significant ultrasound transmissions in the plate material, wherein a filling material of the accessible spaces (36, 37) outside the wells (21) is provided which do not reflect nor transmit waves in an extent higher than +/-10%, preferably +/- 5%.

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