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1. 发明专利

IL251301D0 Boronic acid derivatives , their preparation and medicaments containing them 未知
公开(公告)号：IL251301D0
公开(公告)日：2017-05-29
申请号：IL25130117
申请日：2017-03-21
申请人： MERCK PATENT GMBH , KLEIN MARKUS , SCHADT OLIVER , HASELMAYER PHILIPP , BUSCH MICHAEL
发明人： KLEIN MARKUS , SCHADT OLIVER , HASELMAYER PHILIPP , BUSCH MICHAEL
IPC分类号： C07F20060101
摘要： Compounds of formula (I) are inhibitors of LMP7 and can be employed, inter alia, for the treatment of an autoimmue disorder abnomality or hematological malignancies.

2. 发明专利

IL251301A Boronic acid derivatives , their preparation and medicaments containing them 未知
公开(公告)号：IL251301A
公开(公告)日：2022-02-01
申请号：IL25130117
申请日：2017-03-21
申请人： MERCK PATENT GMBH , KLEIN MARKUS , SCHADT OLIVER , HASELMAYER PHILIPP , BUSCH MICHAEL
发明人： KLEIN MARKUS , SCHADT OLIVER , HASELMAYER PHILIPP , BUSCH MICHAEL
IPC分类号： A61K31/69 , A61P11/00 , A61P11/06 , A61P17/06 , A61P19/02 , A61P29/00 , A61P35/00 , A61P35/02 , A61P37/06
摘要： Compounds of formula (I) are inhibitors of LMP7 and can be employed, inter alia, for the treatment of an autoimmue disorder abnomality or hematological malignancies.

3. 发明专利

IL251300D0 Boronic acid derivatives , their preparation and medicaments containing them 未知
公开(公告)号：IL251300D0
公开(公告)日：2017-05-29
申请号：IL25130017
申请日：2017-03-21
申请人： MERCK PATENT GMBH , KLEIN MARKUS , SCHADT OLIVER , HASELMAYER PHILIPP , BUSCH MICHAEL
发明人： KLEIN MARKUS , SCHADT OLIVER , HASELMAYER PHILIPP , BUSCH MICHAEL
IPC分类号： C07F20060101
摘要： Compounds of formula (I) are inhibitors of LMP7 and can be employed, inter alia, for the treatment of an autoimmue disorder or hematological malignancies.

4. 发明专利

IL251299D0 Boronic acid derivatives , their preparation and medicaments containing them 未知
公开(公告)号：IL251299D0
公开(公告)日：2017-05-29
申请号：IL25129917
申请日：2017-03-21
申请人： MERCK PATENT GMBH , KLEIN MARKUS , SCHADT OLIVER , HASELMAYER PHILIPP , BUSCH MICHAEL
发明人： KLEIN MARKUS , SCHADT OLIVER , HASELMAYER PHILIPP , BUSCH MICHAEL
IPC分类号： C07F20060101
摘要： Compounds of formula (I) are inhibitors of LMP7 and can be employed, inter alia, for the treatment of an autoimmue disorder or hematological malignancies.

5. 发明申请

WO2013045028A1 BENZYL PIPERIDINE COMPOUNDS AS LYSOPHOSPHATIDIC ACID (LPA) RECEPTOR ANTAGONIST 审中-公开
标题翻译：苯甲酸胆碱化合物作为LOSOPHOSPHATIDIC ACID（LPA）受体拮抗剂
公开(公告)号：WO2013045028A1
公开(公告)日：2013-04-04
申请号：PCT/EP2012003771
申请日：2012-09-07
申请人： MERCK PATENT GMBH , SCHIEMANN KAI , STAEHLE WOLFGANG , BUSCH MICHAEL , WIENKE DIRK , POESCHKE OLIVER , BURGER CHRISTA
发明人： SCHIEMANN KAI , STAEHLE WOLFGANG , BUSCH MICHAEL , WIENKE DIRK , POESCHKE OLIVER , BURGER CHRISTA
IPC分类号： C07D401/04 , A61K31/4523 , A61P29/00 , A61P35/00 , C07D407/04 , C07D417/04
CPC分类号： C07D487/04 , A61K31/4525 , A61K31/4535 , A61K31/454 , A61K31/4545 , A61K31/4985 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D471/04
摘要： The invention provides novel substituted benzyl piperidine compounds according to Formula (I) as lysophosphatidic acid (LPA) receptor antagonists, their manufacture and use for the treatment of proliferative or inflammatory diseases, such as cancer, fibrosis or arthritis.
摘要翻译：本发明提供了作为溶血磷脂酸（LPA）受体拮抗剂的式（I）的新型取代的苄基哌啶化合物，其用于治疗增殖性或炎性疾病如癌症，纤维化或关节炎的制备和用途。

6. 发明申请

WO2010136162A3 METHOD FOR PRODUCING A SOLAR MODULE 审中-公开
标题翻译：用于生产太阳能电池组件
公开(公告)号：WO2010136162A3
公开(公告)日：2011-09-01
申请号：PCT/EP2010003137
申请日：2010-05-19
申请人： FRAUNHOFER GES FORSCHUNG , BUSCH MICHAEL , KERN HANS-JUERGEN , SANDER MAGNUS , ECKL OLIVER
发明人： BUSCH MICHAEL , KERN HANS-JUERGEN , SANDER MAGNUS , ECKL OLIVER
IPC分类号： H01L31/048 , H01L31/05
CPC分类号： B29C39/025 , B29C39/10 , B29C39/26 , B29C67/246 , B29K2075/00 , H01L31/048 , H01L31/05 , H01L31/18 , Y02E10/50
摘要： The present invention relates to a method for producing a solar module. A carrier structure (28) is thereby submerged by means of a low-viscosity wetting material, photovoltaic cells (52) are applied to the submerged carrier structure after at least partial curing of the wetting material, wherein contact lines (54) protrude past the coating and can each be brought into contact with connecting conductors. Electrically conducting connections are then produced between the contact lines and the connecting conductors, the top side of the photovoltaic cells (52), and the contact lines and the connecting conductors are submerged in a low-viscosity wetting material that is light-permeable in the cured state, and a cover plate is applied to the at least partially cured, transparent material after at the least partial curing of the transparent wetting material.
摘要翻译：本发明涉及一种用于制造太阳能电池组件。在这种情况下，支撑结构（28）被部分地低粘度通过被水淹没的交联材料的装置之后施加到淹没支撑结构，其中接触线（54）延伸超出所述涂层和在每种情况下与连接导体轨迹的交联材料的光伏电池的至少部分完整的反应（52）相互接触。随后，制备接触线和连接导体轨迹之间的导电连接洪水光伏电池的上表面侧（52）和所述KontaktIeitungen和具有低粘度的交联材料中的连接导体轨迹，其是在固化状态和交联的所述至少部分固化后透明透光材料，盖板施加在至少部分固化的，透光性的材料。

7. 发明申请

WO2009109180A2 SOLAR MODULE 审中-公开
标题翻译：太阳能电池板
公开(公告)号：WO2009109180A2
公开(公告)日：2009-09-11
申请号：PCT/DE2009000305
申请日：2009-03-03
申请人： FRAUNHOFER GES FORSCHUNG , BUSCH MICHAEL , BAGDAHN JOERG
发明人： BUSCH MICHAEL , BAGDAHN JOERG
IPC分类号： H01L31/048
CPC分类号： H01L31/0508 , H01L31/048 , H01L31/055 , Y02E10/52
摘要： The invention relates to a solar module, comprising a solar cell arrangement configured in a planar manner, at the back of which a rear design and at the front of which a radiation-transparent front disk are provided, having a potting compound that surrounds the solar cell arrangement between the rear design and front disk and can solidify and transmits mechanical loads, wherein said potting compound connects the entire surface of the front disk facing the rear design to the rear design and completely encloses the solar cell arrangement. The invention is characterized in that the rear design is configured as a separate module in the form of a plastic support produced by injection molding, compression molding or pressing, or in the form of a flexurally rigid ceramic or organic surface element. The plastic carrier, or the surface element, provide for a metal electrical connecting structure for an electrical connection to the solar cell arrangement, said structure being integrated into the plastic carrier or into the surface element, such that at least one partial region of the connecting structure is completely surrounded by the plastic carrier material or by the ceramic or organic material, and at least one other partial region of the connecting structure has a free contact region facing the solar cell arrangement.
摘要翻译：公开的是具有扁平形式的太阳能电池阵列，在其前侧设置有太阳能电池组件，在靠背结构和辐射透明前面板的背面，与背面侧的结构和挡风玻璃之间的太阳能电池装配件周围，是能够固化和机械负荷的传送面向挡风玻璃以其后侧结构的灌封化合物连接表面在与所述背面结构的整个区域和完全包围太阳能电池阵列。本发明的特征在于，所述后侧结构形成为形式的单独的模块通过注射成型，注射压缩成型或挤压塑料衬底或在刚性陶瓷或有机表面元件的形式制成。所述塑料支承体或表面元件看到集成到塑料载体或在表面元件，用于以这样的方式对太阳能电池阵列的电连接的金属电连接结构需要至少所述终端结构的一部分完全由塑料载体材料或陶瓷或有机材料的包围和具有面向自由接触面积的太阳能电池阵列中的一个的连接结构的至少一个其它部分。

8. 发明专利

AU2015327412B2 Boronic acid derivatives 未知
公开(公告)号：AU2015327412B2
公开(公告)日：2020-01-16
申请号：AU2015327412
申请日：2015-10-01
申请人： MERCK PATENT GMBH
发明人： KLEIN MARKUS , SCHADT OLIVER , HASELMAYER PHILIPP , BUSCH MICHAEL
IPC分类号： C07F5/02 , A61K31/69 , A61P37/00
摘要： Compounds of formula (I) are inhibitors of LMP7 and can be employed, inter alia, for the treatment of an autoimmue disorder or hematological malignancies.

9. 发明专利

AU2012314943B9 Benzyl piperidine compounds as lysophosphatidic acid (LPA) receptor antagonist 未知
公开(公告)号：AU2012314943B9
公开(公告)日：2017-06-08
申请号：AU2012314943
申请日：2012-09-07
申请人： MERCK PATENT GMBH
发明人： SCHIEMANN KAI , STAEHLE WOLFGANG , BUSCH MICHAEL , WIENKE DIRK , POESCHKE OLIVER , BURGER CHRISTA
IPC分类号： C07D401/04 , A61K31/4523 , A61P29/00 , A61P35/00 , C07D407/04 , C07D417/04
摘要： The invention provides novel substituted benzyl piperidine compounds according to Formula (I) as lysophosphatidic acid (LPA) receptor antagonists, their manufacture and use for the treatment of proliferative or inflammatory diseases, such as cancer, fibrosis or arthritis.

10. 发明专利

ES2614872T3 Derivados de 9-(aril o heteroaril)-2-(pirazolilo, pirrolidinilo o ciclopentilo) aminopurina como agentes anticancer 未知
公开(公告)号：ES2614872T3
公开(公告)日：2017-06-02
申请号：ES14705029
申请日：2014-02-11
申请人： MERCK PATENT GMBH
发明人： HOELZEMANN GUENTER , DORSCH DIETER , WEGENER ANSGAR , POESCHKE OLIVER , BUSCH MICHAEL , SEENISAMY JEYAPRAKASHNARAYANAN
IPC分类号： C07D473/32 , A61K31/52 , A61P35/00
摘要： Compuestos de la fórmula I**Fórmula** en la que X representa H, CH3 o NH2, R1 representa Ar o Het, R2 representa pirazolilo, pirrolidinilo o ciclopentilo, cada uno de los cuales es no sustituido o monosustituido por A, [C(R3)2]pAr, [C(R3)2]pHet1, Cyc, CO[C(R3)2]pN(R3)2 o CO[C(R3)2]pHet1, R3 representa H o alquilo no ramificado o ramificado con 1-4 átomos de C, Ar representa fenilo, que es no sustituido o mono-, di- o trisustituido por Hal, A, [C(R3)2]pHet110 , CONH2, CONHA y/o CONA2, Het representa pirazolilo, piridilo, indolilo, isoindolilo, indolinilo, quinolilo o isoquinolilo, cada uno de los cuales es no sustituido o mono- o disustituido por A y/o >=O, Het1 representa pirazolilo, piridilo, pirrolidinilo, piperidinilo, morfolinilo, tetrahidropiranilo o piperazinilo, cada uno de los cuales es no sustituido o mono- o disustituido por A y/o [C(R3)2]pHet2, Het2 representa pirrolidinilo, piperidinilo, morfolinilo o piperazinilo, cada uno de los cuales es no sustituido o monosustituido por A, Cyc representa cicloalquilo con 3-7 átomos de C, que es no sustituido o monosustituido por NH2, A representa alquilo no ramificado o ramificado con 1-6 átomos de C, en donde uno o dos no adyacentes grupos CH- y/o CH2 se pueden reemplazar por átomo de N-, O- y/o S- y en donde 1-7 átomos de H se pueden reemplazar por F o Cl, Hal representa F, Cl, Br o I, p representa 0, 1, 2, 3 o 4, y solvatos, sales, tautómeros y estereoisómeros farmacéuticamente aceptables de los mismos, incluyendo mezclas de los mismos en todas las proporciones.

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