专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

2. 发明专利

SG10201606409TA AMINO ACID SEQUENCES DIRECTED AGAINST IL-17A, IL-17F AND/OR IL17-A/F AND POLYPEPTIDES COMPRISING THE SAME 未知
公开(公告)号：SG10201606409TA
公开(公告)日：2016-09-29
申请号：SG10201606409T
申请日：2012-05-04
申请人： MERCK PATENT GMBH
发明人： ROMMELAERE HEIDI , KOLKMAN JOOST ALEXANDER , SAUNDERS MICHAEL JOHN SCOTT , UNION ANN , CHVATCHKO YOLANDE , PROUDFOOT AMANDA E I , VICARI ALAIN , BRUNIQUEL DENIS , CHEVALET LAURENT , LEGER OLIVIER
摘要： The present invention relates to amino acid sequences that are directed against (as defined herein) any of IL-17A, IL-17F and/or IL-17A/F including combinations thereof, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences (also referred to herein as "amino acid sequences of the invention", "compounds of the invention", and "polypeptides of the invention", respectively).

3. 发明专利

NZ616761A Amino acid sequences directed against il-17a, il-17f and/or il17-a/f and polypeptides comprising the same 未知
公开(公告)号：NZ616761A
公开(公告)日：2016-01-29
申请号：NZ61676112
申请日：2012-05-04
申请人： MERCK PATENT GMBH
发明人： ROMMELAERE HEIDI , KOLKMAN JOOST ALEXANDER , SAUNDERS MICHAEL JOHN SCOTT , UNION ANN , CHVATCHKO YOLANDE , PROUDFOOT AMANDA E I , VICARI ALAIN , BRUNIQUEL DENIS , CHEVALET LAURENT , LEGER OLIVIER
IPC分类号： C07K16/24 , A61K39/395 , A61P37/06 , C07K16/46
摘要： Discloses a polypeptide comprising (i) a first amino acid sequence comprising at least one immunoglobulin single variable domain (ISV), which specifically binds to IL-17F (SEQ ID NO: 840) and to a heterodimer of IL-17A (SEQ ID NO: 839) and IL-17F (SEQ ID NO: 840) but does not specifically bind to IL-17A (SEQ ID NO: 839); and (ii) a second amino acid sequence comprising at least one immunoglobulin single variable domain (ISV), which specifically binds to IL-17A (SEQ ID NO: 839), to IL-17F (SEQ ID NO: 840) and to a heterodimer of IL-17A (SEQ ID NO: 839) and IL-17F (SEQ ID NO: 840), wherein the sequences are as defined in the complete specification.

4. 发明专利

EA035973B1 АМИНОКИСЛОТНЫЕ ПОСЛЕДОВАТЕЛЬНОСТИ, НАПРАВЛЕННЫЕ ПРОТИВ IL-17A, IL-17F И/ИЛИ IL-17A/F, И СОДЕРЖАЩИЕ ИХ ПОЛИПЕПТИДЫ 未知
公开(公告)号：EA035973B1
公开(公告)日：2020-09-08
申请号：EA201391632
申请日：2012-05-04
申请人： MERCK PATENT GMBH
发明人： ROMMELAERE HEIDI , KOLKMAN JOOST ALEXANDER , SAUNDERS MICHAEL JOHN SCOTT , UNION ANN , CHVATCHKO YOLANDE , PROUDFOOT AMANDA E I , VICARI ALAIN , BRUNIQUEL DENIS , CHEVALET LAURENT , LEGER OLIVIER
IPC分类号： C07K16/24 , A61K39/395 , A61P37/06 , C07K16/46
摘要： Изобретениеотноситсяк полипептиду, которыйспецифическисвязываетсяс человеческим IL-17A, человеческим IL-17F и/иличеловеческим IL-17A/F, кприменениютакогополипептида, кспособулечениязаболеванияи кфармацевтическойкомпозиции, содержащейего. Полипептидможетбытьиспользовандлялечениязаболевания, выбранногоизгруппы, состоящейизсистемнойкраснойволчанки, ревматоидногоартрита, остеоартрита, юношескогохроническогоартрита, спондилоартропатий, системногосклероза, идиопатическихвоспалительныхмиопатий, синдромаШегрена, системноговаскулита, саркоидоза, аутоиммуннойгемолитическойанемии, аутоиммуннойтромбоцитопении, тиреоидита, сахарногодиабета, иммуноопосредованныхзаболеванийпочек, демиелинизирующихзаболеванийцентральнойи периферическойнервнойсистемы, такихкакрассеянныйсклероз, идиопатическаядемиелинизирующаяполинейропатияилисиндромГийена-Барреи хроническаявоспалительнаядемиелинизирующаяполинейропатия, болезнейжелчии желчныхпутей, такихкакинфекционныйаутоиммунныйхроническийактивныйгепатит, первичныйбиллиарныйцирроз, гранулематозныйгепатити склерозирующийхолангит, воспалительногозаболеваниякишечника, глютенчувствительнойэнтеропатиии болезниУиппла, аутоиммунныхилииммуноопосредованныхзаболеванийкожи, включающихбуллезныезаболеваниякожи, полиморфнуюэритемуи контактныйдерматит, псориаза, аллергическихзаболеваний, такихкакастма, аллергическийринит, атопическийдерматит, гиперчувствительностьк пищеи крапивница, иммунологическихзаболеванийлегких, такихкакэозинофильнаяпневмония, идиопатическийлегочныйфибрози гиперчувствительныйпневмонит, связанныхс трансплантациейзаболеваний, включающихотторжениетрансплантатаи реакцию "трансплантатпротивхозяина".

5. 发明专利

MY167231A Amino acid sequences directed against IL-17A, IL-17F and/or IL17-A/F and polypeptides comprising the same 未知
公开(公告)号：MY167231A
公开(公告)日：2018-08-14
申请号：MYPI2013702070
申请日：2012-05-04
申请人： MERCK PATENT GMBH
发明人： ROMMELAERE HEIDI , LEGER OLIVIER , KOLKMAN JOOST ALEXANDER , SAUNDERS MICHAEL JOHN SCOTT , UNION ANN , CHVATCHKO YOLANDE , PROUDFOOT AMANDA E I , VICARI ALAIN , BRUNIQUEL DENIS , CHEVALET LAURENT
IPC分类号： A61K39/395 , C07K16/24 , A61P37/06 , C07K16/46
摘要： The present invention relates to amino acid sequences that are directed against (as defined herein) any of IL-17 A, IL- 17F and/or IL-17 A/F including combinations thereof, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences (also referred to herein as “amino acid sequences of the invention”, “compounds of the invention”, and “polypeptides of the invention”, respectively).

6. 发明专利

BR112013028407A2 "sequências de aminoácido direcionadas em relação aos polipeptídeos de il-17a, il-17f e/ou il17-a/f compreendendo as mesmas, seus usos, polipeptídeos, e composição farmacêutica". 未知
公开(公告)号：BR112013028407A2
公开(公告)日：2016-11-29
申请号：BR112013028407
申请日：2012-05-04
申请人： MERCK PATENT GMBH
发明人： VICARI ALAIN , PROUDFOOT AMANDA E I , UNION ANN , BRUNIQUEL DENIS , ROMMELAERE HEIDI , KOLKMAN JOOST ALEXANDER , CHEVALET LAURENT , SAUNDERS MICHAEL JOHN SCOTT , LEGER OLIVIER , CHVATCHKO YOLANDE
IPC分类号： A61K39/395 , A61P37/06 , C07K16/24 , C07K16/46
摘要： resumo patente de invenção: "sequências de aminoácido direcionadas em relação aos polipeptídeos de il-17a, il-17f e/ou il17-a/f compreendendo as mesmas". a presente invenção refere-se às sequências de aminoácido que são direcionadas em relação a (como aqui definido) qualquer um dentre il-17a, il-17f e/ou il-17a/f, inclusive combinações das mesmas, bem como a compostos ou construtos, e em particular proteínas e polipeptídeos que compreendem ou essencialmente consistem em uma ou mais tais sequências de aminoácido (da mesma forma referida aqui como "sequências de aminoácido da invenção", "compostos da invenção", e "polipeptídeos da invenção", respectivamente).

7. 发明专利

AU2012257942A2 Amino acid sequences directed against IL-17A, IL-17F and/or ILl17-A/F and polypeptides comprising the same 未知
公开(公告)号：AU2012257942A2
公开(公告)日：2014-06-05
申请号：AU2012257942
申请日：2012-05-04
申请人： MERCK PATENT GMBH
发明人： ROMMELAERE HEIDI , KOLKMAN JOOST ALEXANDER , SAUNDERS MICHAEL JOHN SCOTT , UNION ANN , CHVATCHKO YOLANDE , PROUDFOOT AMANDA E I , VICARI ALAIN , BRUNIQUEL DENIS , CHEVALET LAURENT , LEGER OLIVIER
IPC分类号： C07K16/24 , A61K39/395 , A61P37/06 , C07K16/46
摘要： The present disclosure relates to amino acid sequences that are directed against (as defined herein) any of IL-17A, IL-17F and/or IL-17A/ F including combinations thereof, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.

8. 发明专利

ES2662371T3 Secuencias de aminoácidos dirigidas contra IL-17A, IL-17F y/o IL-17A/F y polipéptidos que comprenden las mismas 未知
公开(公告)号：ES2662371T3
公开(公告)日：2018-04-06
申请号：ES12726593
申请日：2012-05-04
申请人： MERCK PATENT GMBH
发明人： ROMMELAERE HEIDI , KOLKMAN JOOST ALEXANDER , SAUNDERS MICHAEL JOHN SCOTT , UNION ANN , CHVATCHKO YOLANDE , PROUDFOOT AMANDA E I , VICARI ALAIN , BRUNIQUEL DENIS , CHEVALET LAURENT , LEGER OLIVIER
IPC分类号： C07K16/24 , A61K39/395 , A61P37/06 , C07K16/46
摘要： Un polipéptido que comprende i) una primera secuencia de aminoácidos que comprende al menos un dominio variable único de inmunoglobulina (ISV), que se une específicamente a la IL-17F humana y a un heterodímero de la IL- 17A humana y la IL-17F humana pero no se une específicamente a la IL-17A humana; y ii) una segunda secuencia de aminoácidos que comprende al menos un dominio variable único de inmunoglobulina (ISV), que se une específicamente a la IL-17A humana, a la IL-17F humana y a un heterodímero de la IL-17A humana y la IL-17F humana.

9. 发明专利

AU2012257942B2 Amino acid sequences directed against IL-17A, IL-17F and/or ILl17-A/F and polypeptides comprising the same 未知
公开(公告)号：AU2012257942B2
公开(公告)日：2015-08-20
申请号：AU2012257942
申请日：2012-05-04
申请人： MERCK PATENT GMBH
发明人： ROMMELAERE HEIDI , KOLKMAN JOOST ALEXANDER , SAUNDERS MICHAEL JOHN SCOTT , UNION ANN , CHVATCHKO YOLANDE , PROUDFOOT AMANDA E I , VICARI ALAIN , BRUNIQUEL DENIS , CHEVALET LAURENT , LEGER OLIVIER
IPC分类号： C07K16/24 , A61K39/395 , A61P37/06 , C07K16/46
摘要： The present disclosure relates to amino acid sequences that are directed against (as defined herein) any of IL-17A, IL-17F and/or IL-17A/ F including combinations thereof, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.

10. 发明专利

AU2012257942A1 Amino acid sequences directed against IL-17A, IL-17F and/or ILl17-A/F and polypeptides comprising the same 未知
公开(公告)号：AU2012257942A1
公开(公告)日：2013-05-02
申请号：AU2012257942
申请日：2012-05-04
申请人： ABLYNX NV , MERCK PATENT GMBH
发明人： ROMMELAERE HEIDI , KOLKMAN JOOST ALEXANDER , SAUNDERS MICHAEL JOHN SCOTT , UNION ANN , CHVATCHKO YOLANDE , PROUDFOOT AMANDA E I , VICARI ALAIN , BRUNIQUEL DENIS , CHEVALET LAURENT , LEGER OLIVIER
IPC分类号： C07K16/24 , A61K39/395 , A61P37/06 , C07K16/46
摘要： The present disclosure relates to amino acid sequences that are directed against (as defined herein) any of IL-17A, IL-17F and/or IL-17A/ F including combinations thereof, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式