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1. 发明申请

WO2005016119A2 RADIO-FREQUENCY BASED CATHETER SYSTEM AND METHOD FOR ABLATING BIOLOGICAL TISSUES 审中-公开
标题翻译：基于无线电频率的导管系统及其生物组织研究方法
公开(公告)号：WO2005016119A2
公开(公告)日：2005-02-24
申请号：PCT/US2004/024696
申请日：2004-07-30
申请人： MEDWAVES, INC. , ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
发明人： ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61B
CPC分类号： A61B18/1492 , A61B18/18 , A61B90/39 , A61B2017/003 , A61B2018/00214 , A61B2018/00839 , A61B2018/00875 , A61B2018/1407 , A61B2018/1437
摘要： An improved radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency ("RF") generator for selectively generating high frequency energy in a deployable catheter having a RF co-axial transmission line with a hollow lumen, a RF antenna mounted on the distal portion of the catheter, and steering control lines in the lumen of the transmission line for steering catheter while being inserted into the body vessel and for deflecting the RF antenna to accommodate the contour of the body vessel where tissue ablation is needed. The RF generator having variable output frequency is adapted to generate and communicate RF energy to the RF antenna that minimizes reflected energy from the antenna-tissue interface. In application, the RF antenna establishes line of contact with the body vessel conformable to its internal contour to prescribe the precise tissue ablation pathway despite body vessel movements. The RF antenna is steered by the steering control lines to establish its body vessel conformation. The catheter system is energized and system senses the reflected RF power relative to its output power and adjusts the frequency of the power output to effect impedance match between the transmission line of the system and the tissue ablation load.
摘要翻译：改进的基于射频的导管系统和用于消除患者体内血液中生物组织的方法包括：射频（“RF”）发生器，用于在具有RF同轴传输线的可展开导管中选择性地产生高频能量具有中空管腔，安装在导管的远端部分上的RF天线以及用于转向导管的传输线的内腔中的转向控制线，同时插入到身体容器中并用于偏转RF天线以适应需要组织消融的身体血管。具有可变输出频率的RF发生器适于产生RF通信并将RF能量传送到RF天线，其使得天线 - 组织界面的反射能量最小化。在应用中，RF天线与体内血管建立接触线，以符合其内部轮廓，以规定精确的组织消融路径，尽管身体血管运动。 RF天线由转向控制线转向以建立其身体血管构象。导管系统被通电，系统相对于其输出功率感测反射的RF功率，并且调节功率输出的频率以实现系统的传输线与组织消融负载之间的阻抗匹配。

2. 发明申请

WO2004073766A2 PREFORMED CATHETER SET FOR USE WITH A LINEAR ABLATION SYSTEM TO PRODUCE ABLATION LINES IN THE LEFT AND RIGHT ATRIUM FOR TREATMENT OF ATRIAL FIBRILLATION 审中-公开
标题翻译：用于线性牵引系统的预制导管装置，用于在左心室和右心室内产生用于治疗椎间盘突出的消融线
公开(公告)号：WO2004073766A2
公开(公告)日：2004-09-02
申请号：PCT/US2004/004693
申请日：2004-02-19
申请人： MEDWAVES INC. , FELD, Gregory, K. , ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
发明人： FELD, Gregory, K. , ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61M
CPC分类号： A61B18/1492 , A61B2018/183
摘要： A preformed catheter set for production of linear ablation lines in the left and right atrium for treatment of atrial fibrillation includes at least a first catheter including a pre-shaped distal segment having a distal linear ablation antenna and a U-shaped curve portion proximal to the distal linear ablation antenna.
摘要翻译：用于在左心房和右心房中产生线性消融线的预成型导管套件用于治疗房颤包括至少第一导管，其包括具有远端线性消融天线的预形远端区段和靠近该房间的U形曲线部分远端线性消融天线。

3. 发明申请

WO2003047448A1 RADIO-FREQUENCY-BASED CATHETER SYSTEM WITH IMPROVED DEFLECTION AND STEERING MECHANISMS 审中-公开
标题翻译：具有改进的偏转和转向机构的无线电频率导管系统
公开(公告)号：WO2003047448A1
公开(公告)日：2003-06-12
申请号：PCT/US2002/037886
申请日：2002-11-27
申请人： MEDWAVES, INC.
发明人： ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61B18/18
CPC分类号： H01Q1/42 , A61B18/1492 , A61B2017/003 , A61B2017/00867 , A61B2018/00357 , A61B2018/00839 , C08L2201/12
摘要： A shapeable curvilinear radio-frequency antenna apparatus (110) for ablating biological tissue within the body vessel of a patient includes a flexible catheter body (120) having a distal portion (140) and an elongated lumen (150). Inner and outer coaxially aligned conductors (640, 660) extend within the catheter (120) and are coaxial with the lumen (150). A flexible shapeable curvilinear radio-frequency antenna (250) is carried by the distal portion of the flexible catheter body (120) and is in electrical communication with the inner and outer coaxially aligned conductors (640, 660). The flexible shapeable curvilinear radio-frequency antenna (250) is adaptable to receive and transmit radio-frequency energy for ablating biological tissue and is shapeable between a straight configuration (190) and a curvilinear configuration (180) for creating a curvilinear ablation pattern in biological tissue within the body vessel of a patient.
摘要翻译：一种用于消除患者体内容器内生物组织的可变形曲线射频天线装置，包括具有远侧部分（140）和细长腔（150）的柔性导管主体（120）。内部和外部同轴对准的导体（640,660）在导管（120）内延伸并且与内腔（150）同轴。灵活的可变形的曲线射频天线（250）由柔性导管主体（120）的远端部分承载，并且与内部和外部同轴对准的导体（640,660）电连通。柔性可变形曲线射频天线（250）适于接收和发送用于烧蚀生物组织的射频能量，并且可在直线构型（190）和曲线构型（180）之间成形，用于在生物体中形成曲线消融图案患者体内的组织。

4. 发明公开

EP1460954A1 RADIO−FREQUENCY−BASED CATHETER SYSTEM WITH IMPROVED DEFLECTION AND STEERING MECHANISMS 有权
标题翻译：具有改进的偏转和控制机制高频导管系统
公开(公告)号：EP1460954A1
公开(公告)日：2004-09-29
申请号：EP02804448.5
申请日：2002-11-27
申请人： Medwaves, Inc.
发明人： ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61B18/18 , A61B5/04 , H01Q1/36
CPC分类号： H01Q1/42 , A61B18/1492 , A61B2017/003 , A61B2017/00867 , A61B2018/00357 , A61B2018/00839 , C08L2201/12
摘要： A shapeable curvilinear radio-frequency antenna apparatus (110) for ablating biological tissue within the body vessel of a patient includes a flexible catheter body (120) having a distal portion (140) and an elongated lumen (150). Inner and outer coaxially aligned conductors (640, 660) extend within the catheter (120) and are coaxial with the lumen (150). A flexible shapeable curvilinear radio-frequency antenna (250) is carried by the distal portion of the flexible catheter body (120) and is in electrical communication with the inner and outer coaxially aligned conductors (640, 660). The flexible shapeable curvilinear radio-frequency antenna (250) is adaptable to receive and transmit radio-frequency energy for ablating biological tissue and is shapeable between a straight configuration (190) and a curvilinear configuration (180) for creating a curvilinear ablation pattern in biological tissue within the body vessel of a patient.

5. 发明授权

EP1653874B1 RADIO-FREQUENCY BASED CATHETER SYSTEM AND METHOD FOR ABLATING BIOLOGICAL TISSUES 有权
标题翻译：导管系统上消融生物组织高频基地和方法
公开(公告)号：EP1653874B1
公开(公告)日：2010-12-29
申请号：EP04779679.2
申请日：2004-07-30
申请人： Medwaves, Inc.
发明人： ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61B18/04 , A61B18/12 , A61B18/14
CPC分类号： A61B18/1492 , A61B18/18 , A61B90/39 , A61B2017/003 , A61B2018/00214 , A61B2018/00839 , A61B2018/00875 , A61B2018/1407 , A61B2018/1437
摘要： An improved radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency ('RF') generator for selectively generating high frequency energy in a deployable catheter having a RF co-axial transmission line with a hollow lumen, a RF antenna mounted on the distal portion of the catheter, and steering control lines in the lumen of the transmission line for steering catheter while being inserted into the body vessel and for deflecting the RF antenna to accommodate the contour of the body vessel where tissue ablation is needed.

6. 发明授权

EP1460954B1 RADIO-FREQUENCY BASED CATHETER SYSTEM WITH IMPROVED DEFLECTION AND STEERING MECHANISMS 有权
标题翻译：具有改进的偏转和控制机制高频导管系统
公开(公告)号：EP1460954B1
公开(公告)日：2007-10-10
申请号：EP02804448.5
申请日：2002-11-27
申请人： Medwaves, Inc.
发明人： ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61B18/18 , A61B5/04 , H01Q1/36 , A61B18/14 , A61B18/12
CPC分类号： H01Q1/42 , A61B18/1492 , A61B2017/003 , A61B2017/00867 , A61B2018/00357 , A61B2018/00839 , C08L2201/12
摘要： A shapeable curvilinear radio-frequency antenna apparatus (110) for ablating biological tissue within the body vessel of a patient includes a flexible catheter body (120) having a distal portion (140) and an elongated lumen (150). Inner and outer coaxially aligned conductors (640, 660) extend within the catheter (120) and are coaxial with the lumen (150). A flexible shapeable curvilinear radio-frequency antenna (250) is carried by the distal portion of the flexible catheter body (120) and is in electrical communication with the inner and outer coaxially aligned conductors (640, 660). The flexible shapeable curvilinear radio-frequency antenna (250) is adaptable to receive and transmit radio-frequency energy for ablating biological tissue and is shapeable between a straight configuration (190) and a curvilinear configuration (180) for creating a curvilinear ablation pattern in biological tissue within the body vessel of a patient.

7. 发明公开

EP1653874A2 RADIO-FREQUENCY BASED CATHETER SYSTEM AND METHOD FOR ABLATING BIOLOGICAL TISSUES 有权
标题翻译：导管系统上消融生物组织高频基地和方法
公开(公告)号：EP1653874A2
公开(公告)日：2006-05-10
申请号：EP04779679.2
申请日：2004-07-30
申请人： Medwaves, Inc.
发明人： ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61B18/04
CPC分类号： A61B18/1492 , A61B18/18 , A61B90/39 , A61B2017/003 , A61B2018/00214 , A61B2018/00839 , A61B2018/00875 , A61B2018/1407 , A61B2018/1437
摘要： An improved radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency ('RF') generator for selectively generating high frequency energy in a deployable catheter having a RF co-axial transmission line with a hollow lumen, a RF antenna mounted on the distal portion of the catheter, and steering control lines in the lumen of the transmission line for steering catheter while being inserted into the body vessel and for deflecting the RF antenna to accommodate the contour of the body vessel where tissue ablation is needed.

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