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1. 发明申请

WO2016065227A2 MICROCATHETER SENSOR DESIGN FOR MINIMIZING PROFILE AND IMPACT OF WIRE STRAIN ON SENSOR 审中-公开
标题翻译：微型传感器设计，用于最小化轮廓和线束传感器的影响
公开(公告)号：WO2016065227A2
公开(公告)日：2016-04-28
申请号：PCT/US2015/057058
申请日：2015-10-23
申请人： MEDTRONIC VASCULAR INC.
发明人： MURPHY, Christopher , MCCAFFREY, Gerry , SWEENEY, Fiachra , WARD, Sean
IPC分类号： A61B5/0215
CPC分类号： A61B5/0215 , A61B5/02007 , A61B5/026 , A61B5/6852 , A61B2562/0247 , A61B2562/028 , A61B2562/187 , A61B2562/227
摘要： A catheter, such as a fractional flow reserve catheter, includes an elongate shaft having a pressure sensing wire extending to the distal portion of the elongate shaft. The wire has a pressure sensor mounted on the distal end for measuring a pressure of a fluid within lumen of vessel. The pressure sensor wire is disposed within a pocket formed adjacent to the pressure sensor thereby minimizing the profile of the catheter. Bending stresses experienced by a pressure sensor mounted to a fractional flow reserve catheter when tracking the catheter through the vasculature creates a distortion of the sensor resulting in an incorrect pressure reading or bend error. In order to isolate the sensor from bending stresses, the sensor is spaced apart from the pressure sensor wire to allow the pressure sensor and the pressure sensor wire to move independently from one another.
摘要翻译：诸如分数储备导管的导管包括细长轴，其具有延伸到细长轴的远端部分的压力感测线。导线具有安装在远端的压力传感器，用于测量容器内腔内的流体的压力。压力传感器线设置在邻近压力传感器形成的凹穴内，从而使导管的轮廓最小化。当通过脉管系统跟踪导管时，安装到分流储备导管上的压力传感器经历的弯曲应力会导致传感器的变形，从而导致不正确的压力读数或弯曲误差。为了将传感器与弯曲应力隔离，传感器与压力传感器线间隔开，以使压力传感器和压力传感器线彼此独立地移动。

2. 发明申请

WO2011035222A1 METHOD OF FORMING HOLLOW TUBULAR DRUG ELUTING MEDICAL DEVICES 审中-公开
标题翻译：形成中空管药液治疗医疗器械的方法
公开(公告)号：WO2011035222A1
公开(公告)日：2011-03-24
申请号：PCT/US2010/049439
申请日：2010-09-20
申请人： MEDTRONIC VASCULAR INC. , MAUCH, Kevin , WARD, Sean , JAMOUS, Aram
发明人： MAUCH, Kevin , WARD, Sean , JAMOUS, Aram
IPC分类号： A61L31/16 , A61F2/86
CPC分类号： A61M31/002 , A61F2/88 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2240/001 , A61F2250/0068 , A61L31/16 , Y10T29/49995
摘要： A method of a forming a hollow, drug-eluting medical device includes utilizing a hollow wire having an outer member and a lumen of the outer member, and filling the lumen with a fluid to form a supported hollow wire. The supported hollow wire is shaped into a stent pattern. Openings are formed through the outer member. The supported hollow wire is processed to remove the fluid from the lumen of the outer member without adversely affecting the outer member, leaving the hollow wire shaped into a stent pattern. The lumen is filled with a biologically or pharmacologically active substance.
摘要翻译：形成中空的药物洗脱医疗装置的方法包括利用具有外部构件的外部构件和内腔的中空丝，并且用流体填充内腔以形成支撑的中空丝。支撑的中空丝被成形为支架图案。开口通过外部构件形成。处理支撑的中空丝线以从外部构件的内腔中除去流体，而不会对外部构件产生不利影响，从而将空心线材成形为支架图案。管腔充满生物或药理活性物质。

3. 发明申请

WO2017053663A1 GUIDE EXTENSION CATHETER WITH PERFUSION OPENINGS 审中-公开
标题翻译：指导延伸导管与灌注开口
公开(公告)号：WO2017053663A1
公开(公告)日：2017-03-30
申请号：PCT/US2016/053253
申请日：2016-09-23
申请人： MEDTRONIC VASCULAR INC.
发明人： O'CONNELL, Barry , MORRISSEY, Michael , WARD, Sean , TUOHY, John , DONEGAN, Michael (Mick)
IPC分类号： A61M25/00 , A61M25/06
CPC分类号： A61M25/005 , A61M25/007 , A61M2025/0004 , A61M2025/0681
摘要： A guide extension catheter 100 includes a proximal shaft 102, a distal shaft 104, and a plurality of perfusion openings 106. The distal shaft includes a jacket 118 and a helical coil structure 120 embedded in the jacket 118, the distal shaft defining a lumen. The plurality of perfusion openings are disposed though the jacket of the distal shaft between windings of the helical coil structure. The guide extension catheter provides additional back support to the guide catheter. The plurality of perfusion openings allow fluid communication between an area outside the guide extension catheter and the lumen.
摘要翻译：引导延伸导管100包括近端轴102，远侧轴104和多个灌注开口106.远端轴包括护套118和嵌入护套118中的螺旋线圈结构120，远侧轴限定内腔。多个灌注开口通过远端轴的护套设置在螺旋线圈结构的绕组之间。引导延伸导管为引导导管提供额外的后支撑。多个灌注开口允许在引导延伸导管外部的区域与内腔之间的流体连通。

4. 发明申请

WO2018200874A1 FFR CATHETER WITH COVERED DISTAL PRESSURE SENSOR AND METHOD OF MANUFACTURE 审中-公开
公开(公告)号：WO2018200874A1
公开(公告)日：2018-11-01
申请号：PCT/US2018/029650
申请日：2018-04-26
申请人： MEDTRONIC VASCULAR, INC.
发明人： MCCAFFREY, Gerry , WARD, Sean
IPC分类号： A61B5/00 , A61B5/0215 , A61B5/02
摘要： A distal shaft for measuring pressure distal of a stenosis includes a housing, a pressure sensor, a cover, a tip, and an aperture. The pressure sensor is mounted in the housing. The cover is coupled to the housing and covers the pressure sensor. The tip is coupled to a distal end of the housing. The aperture is disposed through the tip and/or cover. The aperture is configured to allow blood flow to the pressure sensor. The cover further includes a coupling mechanism or coupling that couples the cover to the housing. The coupling mechanism may be a snap-fit mechanism, a friction-fit mechanism, and/or an adhesive.

5. 发明申请

WO2018063859A1 PRESSURE MEASURING CATHETER WITH ADENOSINE INFUSION 审中-公开
标题翻译：测量输注腺苷的导管
公开(公告)号：WO2018063859A1
公开(公告)日：2018-04-05
申请号：PCT/US2017/052271
申请日：2017-09-19
申请人： MEDTRONIC VASCULAR INC.
发明人： MCCAFFREY, Gerry , KELLY, John , WARD, Sean
IPC分类号： A61B5/02 , A61B5/026 , A61B5/0215 , A61B5/00 , A61M25/00
摘要： An intracoronary catheter measures pressure distal to a lesion (Pd) and has a fluid lumen for administers adenosine to a patient's vasculature. A controller is configured to provide an injection of adenosine, wait for a period of time, measure Pd, and compare Pd to the Pd measured before the injection of the adenosine. If the difference between the pressures is small or below a threshold, the controller will stop further injections of adenosine because Pd has been determined to be at a relatively constant value. If the pressure difference is large or above a threshold, the controller will provide another adenosine injection, wait for a time period and again measure Pd and compare it to the previous Pd. This process will continue until the measured Pd reaches a relatively constant value.
摘要翻译：冠状动脉内导管测量病变远端的压力（Pd），并具有用于向患者的脉管系统施用腺苷的流体腔。控制器配置为提供腺苷的注射，等待一段时间，测量Pd，并将Pd与注射腺苷之前测量的Pd进行比较。如果压力差小或低于阈值，控制器将停止进一步注射腺苷，因为Pd已被确定为处于相对恒定的值。如果压力差大于或高于阈值，控制器将提供另一次腺苷注射，等待一段时间并再次测量Pd并将其与先前的Pd进行比较。这个过程将继续，直到测量的Pd达到一个相对恒定的值。

6. 发明申请

WO2017100472A1 CATHETER WITH A LUMEN SHAPED AS AN IDENTIFICATION SYMBOL 审中-公开
标题翻译：带有流明标识作为标识符号的导管
公开(公告)号：WO2017100472A1
公开(公告)日：2017-06-15
申请号：PCT/US2016/065655
申请日：2016-12-08
申请人： MEDTRONIC VASCULAR INC.
发明人： TUOHY, John , WARD, Sean
IPC分类号： A61M25/01 , A61M25/00 , A61B90/96 , A61B90/00
CPC分类号： A61M25/0023 , A61B90/39 , A61B90/96 , A61B2090/3933 , A61B2090/3966 , A61M25/0009 , A61M25/0108 , A61M31/005 , A61M2205/32 , A61M2205/6072 , A61M2207/00 , B29C59/16 , B29L2031/7543
摘要： A catheter (100) includes a catheter shaft having a shaft wall and a lumen (135) extending longitudinally within the shaft wall. The lumen is bounded in radially outward and radially inward directions. The lumen includes a feed portion (138) and an identification symbol (140) fluidly connected to the feed portion. The lumen is configured to receive a contrast media. The lumen may be formed by a channel (130) formed in an outer surface of a first shaft (120) of the catheter shaft, and a covering (115) disposed around the outer surface of the first shaft to cover the channel.
摘要翻译：导管（100）包括具有轴壁和在轴壁内纵向延伸的内腔（135）的导管轴。内腔沿径向向外和径向向内方向界定。内腔包括馈送部分（138）和流体连接到馈送部分的识别符号（140）。内腔配置成接收造影剂。内腔可以由形成在导管轴的第一轴（120）的外表面中的通道（130）和围绕第一轴的外表面布置以覆盖通道的覆盖物（115）形成。 p>

7. 发明授权

EP2477673B1 METHOD OF FORMING HOLLOW TUBULAR DRUG ELUTING MEDICAL DEVICES 有权
标题翻译：形成中空管药物医疗装置的方法
公开(公告)号：EP2477673B1
公开(公告)日：2014-11-26
申请号：EP10766152.2
申请日：2010-09-20
申请人： Medtronic Vascular Inc.
发明人： MAUCH, Kevin , WARD, Sean , JAMOUS, Aram
IPC分类号： A61L31/16 , A61F2/88
CPC分类号： A61M31/002 , A61F2/88 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2240/001 , A61F2250/0068 , A61L31/16 , Y10T29/49995

8. 发明公开

EP2477673A1 METHOD OF FORMING HOLLOW TUBULAR DRUG ELUTING MEDICAL DEVICES 有权
标题翻译：形成中空管药物医疗装置的方法
公开(公告)号：EP2477673A1
公开(公告)日：2012-07-25
申请号：EP10766152.2
申请日：2010-09-20
申请人： Medtronic Vascular Inc.
发明人： MAUCH, Kevin , WARD, Sean , JAMOUS, Aram
IPC分类号： A61L31/16 , A61F2/86
CPC分类号： A61M31/002 , A61F2/88 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2240/001 , A61F2250/0068 , A61L31/16 , Y10T29/49995
摘要： A method of a forming a hollow, drug-eluting medical device includes utilizing a hollow wire having an outer member and a lumen of the outer member, and filling the lumen with a fluid to form a supported hollow wire. The supported hollow wire is shaped into a stent pattern. Openings are formed through the outer member. The supported hollow wire is processed to remove the fluid from the lumen of the outer member without adversely affecting the outer member, leaving the hollow wire shaped into a stent pattern. The lumen is filled with a biologically or pharmacologically active substance.
摘要翻译：一种形成空心的药物洗脱医疗装置的方法包括利用具有外部构件和外部构件的内腔的中空线，并且用流体填充内腔以形成支撑的中空线。被支撑的空心线被成形为支架图案。开口通过外部构件形成。处理被支撑的中空线以从外部构件的内腔移除流体而不会不利地影响外部构件，使中空线成形为支架图案。内腔充满生物或药理活性物质。

9. 发明公开

EP3518752A1 PRESSURE MEASURING CATHETER WITH ADENOSINE INFUSION 审中-公开
公开(公告)号：EP3518752A1
公开(公告)日：2019-08-07
申请号：EP17784073.3
申请日：2017-09-19
申请人： Medtronic Vascular Inc.
发明人： MCCAFFREY, Gerry , KELLY, John , WARD, Sean
IPC分类号： A61B5/02 , A61B5/026 , A61B5/0215 , A61B5/00 , A61M25/00

10. 发明授权

EP3209199B1 MICROCATHETER SENSOR DESIGN FOR MINIMIZING PROFILE AND IMPACT OF WIRE STRAIN ON SENSOR 有权
公开(公告)号：EP3209199B1
公开(公告)日：2019-04-24
申请号：EP15794384.6
申请日：2015-10-23
申请人： Medtronic Vascular Inc.
发明人： MURPHY, Christopher , MCCAFFREY, Gerry , SWEENEY, Fiachra , WARD, Sean
IPC分类号： A61B5/0215 , A61B5/026 , A61M25/00 , A61M25/09

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