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1. 发明申请

WO2013162690A1 RADIOPAQUE ENHANCED COBALT ALLOY FOR STENTS 审中-公开
标题翻译：放射性增强钴合金
公开(公告)号：WO2013162690A1
公开(公告)日：2013-10-31
申请号：PCT/US2013/026942
申请日：2013-02-20
申请人： MEDTRONIC VASCULAR INC.
发明人： THOMPSON, Dustin
IPC分类号： A61L31/02 , C22C19/07
CPC分类号： A61F2/915 , A61F2/82 , A61F2002/91558 , A61F2210/0076 , A61F2250/0098 , A61L31/022 , A61L31/18 , C22C19/07
摘要： A stent is formed of at least a cobalt-based alloy. The cobalt-based alloy may include 10-35 weight % metal member selected from the group consisting of platinum (Pt), gold (Au), iridium (Ir), osmium (Os), rhenium (Re), tungsten (W), palladium (Pd), tantalum (Ta), and combinations thereof; 16-21 weight % chromium (Cr); 9-12 weight % molybdenum (Mo); 0-25 weight % nickel (Ni); and balance cobalt (Co). The cobalt-based alloy may be a thin outer shell of a hollow stent. The cobalt-based alloy may be used to form at least one of an inner core and an outer shell of a core-shell structure of a stent. The cobalt-based alloy may be used to form an end of a wire for forming a stent.
摘要翻译：支架由至少一种钴基合金形成。钴基合金可以包括选自铂（Pt），金（Au），铱（Ir），锇（Os），铼（Re），钨（W），钯（Pd），钽（Ta）及其组合; 16-21重量％铬（Cr）; 9-12重量％钼（Mo）; 0-25重量％镍（Ni）; 并平衡钴（Co）。钴基合金可以是中空支架的薄外壳。钴基合金可以用于形成支架的核 - 壳结构的内芯和外壳中的至少一个。钴基合金可用于形成用于形成支架的线的端部。

2. 发明申请

WO2009088783A2 OBSTRUCTION REMOVAL SYSTEM 审中-公开
标题翻译：取走系统
公开(公告)号：WO2009088783A2
公开(公告)日：2009-07-16
申请号：PCT/US2008/088234
申请日：2008-12-23
申请人： MEDTRONIC VASCULAR INC. , THOMPSON, Dustin , PERKINS, DH , JOHNSON, Jeremy , SILVER, Michele , MAUCH, Kevin , MACAULAY, Patrick
发明人： THOMPSON, Dustin , PERKINS, DH , JOHNSON, Jeremy , SILVER, Michele , MAUCH, Kevin , MACAULAY, Patrick
IPC分类号： A61B17/22 , A61B17/00 , A61B17/32 , A61B10/02
CPC分类号： A61B17/320758 , A61B10/0266 , A61B17/320708 , A61B17/320725 , A61B2010/0225 , A61B2017/00345 , A61B2017/00398 , A61B2017/00867 , A61B2017/320008 , A61B2017/320012 , A61B2017/32006 , A61B2017/320064 , A61B2017/320741
摘要： An obstruction removal system for percutaneous removal of clots or obstructions within the vascular system is disclosed. The obstruction removal system includes a multi-lumen catheter with a plurality of circulating capture devices attached to or integral with a drive belt. The circulating capture or interference devices affect removal of the clot or obstruction bit-by-bit through a series of passes. The obstruction removal system may include one or more drive mechanisms, such as a pulley system and/or a vacuum source and/or a pressurization source, on its proximal end for driving the drive belt and capture devices through the catheter in a circulating manner. The obstruction removal system may also include one or more cleaning mechanisms, such as a vacuum chamber and/or a fluid rinse chamber, for removing the captured clot pieces from the capture devices.
摘要翻译：公开了一种用于经皮去除血管系统内的血块或障碍物的阻塞去除系统。阻塞去除系统包括多腔导管，其具有附接到驱动带或与传动带一体的多个循环捕获装置。循环捕获或干扰装置通过一系列通路影响凝块的清除或逐位阻塞。障碍物移除系统可以在其近端包括一个或多个驱动机构，例如皮带轮系统和/或真空源和/或加压源，用于驱动驱动带并以循环方式通过导管捕获装置。阻塞去除系统还可以包括一个或多个清洁机构，例如真空室和/或流体冲洗室，用于从捕获装置移除捕获的凝块。

3. 发明申请

WO2011126676A1 STENT WITH THERAPEUTIC SUBSTANCE 审中-公开
标题翻译：具有治疗药物的STENT
公开(公告)号：WO2011126676A1
公开(公告)日：2011-10-13
申请号：PCT/US2011/028349
申请日：2011-03-14
申请人： MEDTRONIC VASCULAR INC. , THOMPSON, Dustin , ADLER, Paus , ARREGUIN, Maria , MAUCH, Kevin , STORMENT, Christopher , ENSIGN, Lance , ZIMMERMAN, Stephen
发明人： THOMPSON, Dustin , ADLER, Paus , ARREGUIN, Maria , MAUCH, Kevin , STORMENT, Christopher , ENSIGN, Lance , ZIMMERMAN, Stephen
IPC分类号： A61F2/90 , A61F2/00
CPC分类号： A61F2/90 , A61F2250/0067 , A61F2250/0068 , B21F45/008
摘要： A stent (10) includes a wave form that includes a cable (14) including a plurality of strands (316). The wave form has a plurality of struts (18) and a plurality of crowns (20), with each crown connecting two adjacent struts. The wave form is wrapped around a longitudinal axis at a pitch to define a plurality of helical turns. The stent includes a filler located within the cable. The filler includes a therapeutic substance.
摘要翻译：支架（10）包括波形，其包括包括多个股线（316）的电缆（14）。波形具有多个支柱（18）和多个冠部（20），每个冠部连接两个相邻的支柱。波形以间距缠绕在纵向轴线上以限定多个螺旋形匝。支架包括位于电缆内的填充物。填料包括治疗物质。

4. 发明申请

WO2011053467A1 IVC FILTER WITH DRUG DELIVERY 审中-公开
标题翻译： IVC过滤器与药物递送
公开(公告)号：WO2011053467A1
公开(公告)日：2011-05-05
申请号：PCT/US2010/052735
申请日：2010-10-14
申请人： MEDTRONIC VASCULAR INC. , THOMPSON, Dustin , PERKINS, D. H.
发明人： THOMPSON, Dustin , PERKINS, D. H.
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2002/016 , A61F2230/005 , A61F2230/0067 , A61F2230/0091 , A61F2250/0068
摘要： Retrievable inferior vena cava filters are disclosed. Such filters provide for easy removal of the filter and provide drug delivery for dissolution of captured emboli. Methods of using such systems for the prevention, capture, dissolution and removal of emboli are described.
摘要翻译：公开了可检索的下腔静脉滤器。这种过滤器提供容易地去除过滤器并提供用于溶出捕获的栓子的药物递送。描述了使用这种系统来预防，捕获，溶解和去除栓子的方法。

5. 发明申请

WO2009088750A1 OBSTRUCTION REMOVAL SYSTEM 审中-公开
标题翻译：取走系统
公开(公告)号：WO2009088750A1
公开(公告)日：2009-07-16
申请号：PCT/US2008/088032
申请日：2008-12-22
申请人： MEDTRONIC VASCULAR INC. , THOMPSON, Dustin , PERKINS, Dh , JOHNSON, Jeremy , SILVER, Michele , MAUCH, Kevin
发明人： THOMPSON, Dustin , PERKINS, Dh , JOHNSON, Jeremy , SILVER, Michele , MAUCH, Kevin
IPC分类号： A61B17/22 , A61B17/00 , A61B17/32 , A61B10/02
CPC分类号： A61B17/320758 , A61B10/0266 , A61B17/32002 , A61B17/320708 , A61B17/320725 , A61B2010/0225 , A61B2017/00345 , A61B2017/00867 , A61B2017/320008 , A61B2017/320012 , A61B2017/32006 , A61B2017/320064 , A61B2017/320741
摘要： An obstruction removal system (100) for percutaneous removal of clots or obstructions within the vascular system is disclosed. The obstruction removal system includes a multi-lumen catheter (102) with a plurality of circulating capture devices (114) occurring along a drive belt (112). The plurality of capture devices may be' basket-like devices attached to the drive belt, or may be formed by integral coiled or protuberant sections of the drive belt. The circulating capture or interference devices affect removal of the clot or obstruction bit-by-bit through a series of passes.
摘要翻译：公开了一种用于经皮去除血管系统内的凝块或障碍物的阻塞去除系统（100）。阻塞去除系统包括具有多个循环捕获装置（114）的多腔导管（102），沿着驱动带（112）发生。多个捕获装置可以是“连接到驱动带的篮状装置”，或者可以由驱动带的一体的卷绕或突出部分形成。循环捕获或干扰装置通过一系列通路影响凝块的清除或逐位阻塞。

6. 发明申请

WO2014152131A1 WELDED STENT AND STENT DELIVERY SYSTEM 审中-公开
标题翻译：焊接的STENT和STENT交付系统
公开(公告)号：WO2014152131A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/026984
申请日：2014-03-14
申请人： MEDTRONIC VASCULAR INC.
发明人： THOMPSON, Dustin
IPC分类号： A61F2/86
CPC分类号： A61F2/86 , A61F2/95 , A61F2/966 , A61F2002/825 , A61F2220/0058 , A61F2240/001 , A61F2250/0031 , A61L31/022 , A61L31/148 , B23K9/007 , B23K11/11 , B23K26/22 , B23K31/02
摘要： A welded stent and stent delivery system, with a stent including a first strut having a first strut nickel titanium alloy layer and nickel titanium soluble core, the first strut nickel titanium alloy layer being disposed around the first strut nickel titanium soluble core; and a second strut having a second strut nickel titanium alloy layer and nickel titanium soluble core, the second strut nickel titanium alloy layer being disposed around the second strut nickel titanium soluble core, the second strut nickel titanium alloy layer being connected to the first strut nickel titanium alloy layer with a weld. The first and second strut nickel titanium alloy layers are made of a nickel titanium alloy, the first and second strut nickel titanium soluble cores are made of a nickel titanium soluble material, and the weld is made of an alloy of the nickel titanium alloy and the nickel titanium soluble material.
摘要翻译：一种焊接的支架和支架输送系统，其中支架包括具有第一支柱镍钛合金层和镍钛可溶性芯的第一支柱，第一支柱镍钛合金层设置在第一支柱镍钛可溶芯周围; 以及具有第二支柱镍钛合金层和镍钛可溶性芯的第二支柱，所述第二支柱镍钛合金层设置在所述第二支柱镍钛可溶性芯周围，所述第二支柱镍钛合金层连接到所述第一支柱镍钛合金层与焊缝。第一和第二支撑镍钛合金层由镍钛合金制成，第一和第二支柱镍钛可溶性芯由镍钛可溶性材料制成，焊缝由镍钛合金和镍钛可溶性材料。

7. 发明申请

WO2013162691A1 RADIOPAQUE ENHANCED NICKEL ALLOY FOR STENTS 审中-公开
标题翻译：放射性增强镍合金
公开(公告)号：WO2013162691A1
公开(公告)日：2013-10-31
申请号：PCT/US2013/027161
申请日：2013-02-21
申请人： MEDTRONIC VASCULAR INC.
发明人： THOMPSON, Dustin
IPC分类号： C22C19/05 , A61L31/02
CPC分类号： A61F2/82 , A61L31/022 , A61L31/18 , B23K35/0266 , B23K35/3033 , C22C1/02 , C22C19/051 , C22C19/055 , C22C19/056 , C22C30/00 , C22F1/10
摘要： A stent includes a nickel-based alloy that includes 10-35 weight % metal member selected from the group consisting of platinum (Pt), gold (Au), iridium (Ir), osmium (Os), rhenium (Re), palladium (Pd), tantalum (Ta), and combinations thereof; 0-6 weight % cobalt (Co); 17-24 weight % chromium (Cr); 13-15 weight % tungsten (W); 0-3 weight % molybdenum (Mo); 0-5 weight % iron (Fe); and balance nickel (Ni). The nickel -based alloy may be a thin outer shell of a hollow stent. The nickel-based alloy may be used to form at least one of an inner core and an outer shell of a core-shell structure of a stent.
摘要翻译：支架包括镍基合金，其包括选自铂（Pt），金（Au），铱（Ir），锇（Os），铼（Re），钯（ Pd），钽（Ta）及其组合; 0-6重量％钴（Co）; 17-24重量％铬（Cr）; 13-15重量％钨（W）; 0-3重量％钼（Mo）; 0-5重量％铁（Fe）; 并平衡镍（Ni）。镍基合金可以是中空支架的薄外壳。镍基合金可以用于形成支架的核 - 壳结构的内芯和外壳中的至少一个。

8. 发明申请

WO2013154666A1 HOLLOW DRUG-FILLED STENT AND METHOD OF FORMING HOLLOW DRUG-FILLED STENT 审中-公开
标题翻译：中空药液填充瓶和形成中药液灌注液的方法
公开(公告)号：WO2013154666A1
公开(公告)日：2013-10-17
申请号：PCT/US2013/025688
申请日：2013-02-12
申请人： MEDTRONIC VASCULAR INC.
发明人： BIENVENU, Ryan , MITCHELL, James E. , THOMPSON, Dustin
IPC分类号： A61F2/86 , A61L31/16 , A61K31/16
CPC分类号： A61F2/915 , A61F2/86 , A61F2002/91575 , A61F2230/0091 , A61F2240/001 , A61F2250/0068 , A61F2250/0098 , A61L31/022 , A61L31/16 , A61L31/18
摘要： A stent is formed from a wire (508) having an outer member (522) and a radiopaque core member (526) disposed within a portion of the outer member, and an annular lumen between the radiopaque core member and the outer member. A substance (512) is disposed in the annular lumen to be eluted through at least one opening (504) disposed through the outer member. A plurality of radiopaque core members are disposed within portions of the outer member and are separated by lumens defined by the inner surface of the outer member. The lumens and annular lumens are in fluid communication with each other. In a method for making the stent, a composite wire including an outer member, an intermediate member, and a core member is shaped into a stent pattern and processed to remove the intermediate member and portions of the radiopaque core member, without damaging the outer member.
摘要翻译：支架由具有外部构件（522）和设置在外部构件的一部分内的不透射线芯构件（526）的线（508）形成，以及位于不透射线芯构件和外部构件之间的环形腔。物质（512）设置在环形腔中以通过穿过外部构件设置的至少一个开口（504）被洗脱。多个不透射线的芯构件设置在外部构件的部分内并且由外部构件的内表面限定的腔分开。管腔和环形腔相互流体连通。在制造支架的方法中，将包括外部构件，中间构件和芯部构件的复合线材成形为支架图案并进行处理以去除不透射线的芯构件的中间构件和部分，而不损坏外部构件。

9. 发明申请

WO2011059630A1 INDWELLING TEMPORARY IVC FILTER SYSTEM WITH DRUG DELIVERY AND ASPIRATION 审中-公开
标题翻译：使用药物递送和吸入来维持临时IVC过滤系统
公开(公告)号：WO2011059630A1
公开(公告)日：2011-05-19
申请号：PCT/US2010/052690
申请日：2010-10-14
申请人： MEDTRONIC VASCULAR INC. , THOMPSON, Dustin , PERKINS, D. H.
发明人： THOMPSON, Dustin , PERKINS, D. H.
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61F2230/0091 , A61F2250/0068
摘要： Indwelling temporary inferior vena cava filter systems are disclosed. Such filter systems provide for easy removal of the filter without the need for additional invasive procedures and provide for dissolution and aspiration of captured emboli. Methods of using such systems for the dissolution, capture and removal of emboli are described.
摘要翻译：公开了留置临时下腔静脉过滤系统。这种过滤系统提供了容易地去除过滤器而不需要额外的侵入性程序并提供了捕获的栓塞的溶解和抽吸。描述了使用这种系统来溶解，捕获和去除栓子的方法。

10. 发明申请

WO2014018769A2 MATCHED END STIFFNESS STENT AND METHOD OF MANUFACTURE 审中-公开
标题翻译：相匹配的硬度和制造方法
公开(公告)号：WO2014018769A2
公开(公告)日：2014-01-30
申请号：PCT/US2013/052086
申请日：2013-07-25
申请人： MEDTRONIC VASCULAR INC.
发明人： THOMPSON, Dustin
IPC分类号： A61F2/88
CPC分类号： A61F2/88 , A61F2220/0058 , A61F2250/0018 , A61F2250/0036
摘要： The matched end stiffness stent system and method of manufacture includes a stent delivery system including a catheter, balloon, and stent. The stent includes a wire bent into a waveform having a constant frequency and wrapped into a hollow cylindrical shape, the wire having a body portion having body struts connected between body crowns, the body struts having substantially equal lengths, and the waveform in the body portion having a constant amplitude; and at least one end portion attached to the body portion, the at least one end portion having end struts connected between end crowns, the waveform in the at least one end portion having an amplitude different from the constant amplitude of the waveform in the body portion. The cross sections of the end struts are selected so that the body struts and the end struts have a substantially equal stiffnesses in response to an applied load.
摘要翻译：匹配的端部刚性支架系统和制造方法包括包括导管，球囊和支架的支架输送系统。支架包括弯曲成具有恒定频率并缠绕成中空圆柱形状的波形的线，该线具有主体部分，主体部分具有连接在主体冠之间的主体支柱，主体支柱具有基本相等的长度，并且主体部分中的波形具有恒定幅度; 以及至少一个端部，其附接到所述主体部分，所述至少一个端部具有连接在端部冠部之间的端部支柱，所述至少一个端部部分中的波形具有与所述主体部分中的波形的恒定幅度不同的幅度。选择端支柱的横截面，使得主体支柱和端支柱响应于所施加的负载具有基本相等的刚度。

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