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1. 发明申请

WO2016077661A1 VISUAL AND TACTILE ASSESSMENT TOOL FOR ATTACHING TO A MOBILE DEVICE 审中-公开
标题翻译：用于连接移动设备的视觉和触觉评估工具
公开(公告)号：WO2016077661A1
公开(公告)日：2016-05-19
申请号：PCT/US2015/060512
申请日：2015-11-13
申请人： MEDTRONIC VASCULAR, INC.
发明人： O'CONNELL, Barry , DOWLING, Brian , SMEDLEY, James
IPC分类号： H04M1/21 , A61B5/02 , G06F1/16
CPC分类号： H04N5/2254 , A61B5/02007 , A61B5/7425 , G02B25/002 , G02B25/02 , G06F1/163 , G06F1/1632 , G06F1/1686 , H04M1/21
摘要： A selectively attachable and removable visual and tactile assessment tool or clip for use with a mobile device is provided. Clip is an elongate member forming a curvilinear shape having a magnifying lens at a distal end thereof. Clip has a transparent tubular member disposed between first and second openings through the body portion of the clip. Tubular member has varying internal diameters to simulate, for example, the constriction or stenosis of a patient's vessel lumen. Once clip is attached to mobile device and the magnifying lens is positioned over the camera of the mobile device, a catheter is inserted through tubular member. The magnifying lens enlarges the size of the catheter displayed on the screen of the mobile device.
摘要翻译：提供了一种用于移动设备的可选择性地附接和可拆卸的视觉和触觉评估工具或夹子。夹子是形成在其远端具有放大透镜的曲线形状的细长构件。夹具具有通过夹子的主体部分设置在第一和第二开口之间的透明管状构件。管状构件具有不同的内径以模拟例如患者血管腔的收缩或狭窄。一旦将夹子连接到移动设备并且放大镜被定位在移动设备的相机上方，则通过管状构件插入导管。放大镜放大显示在移动设备的屏幕上的导管的尺寸。

2. 发明申请

WO2017214434A1 DRUG-ELUTING STENT FORMED FROM A DEFORMABLE HOLLOW STRUT FOR A CUSTOMIZABLE ELUTION RATE 审中-公开
标题翻译：用于可定制选率的由可变形空心支架形成的药物支架
公开(公告)号：WO2017214434A1
公开(公告)日：2017-12-14
申请号：PCT/US2017/036607
申请日：2017-06-08
申请人： MEDTRONIC VASCULAR INC.
发明人： CIAN, Ryan , HOBBINS, David , NOLAN, Shane , SAYERS, Michael , KEANE, Eamon , DOWLING, Brian , COPE, Jonathan , O'DONOVAN, Conor
IPC分类号： A61F2/915
摘要： Methods and apparatus are disclosed for customizing an elution rate of a stent. The stent includes a hollow strut that forms the stent, the hollow strut defining a lumenal space, a drug formulation disposed within the lumenal space of the hollow strut, and at least one side port for eluting the drug formulation in vivo . When the stent is in the radially expanded configuration the hollow strut is deformable from a first configuration that has a first elution rate for the drug formulation to a second configuration that has a second elution rate for the drug formulation. The second elution rate is faster than the first elution rate. The hollow strut deforms from the first configuration to the second configuration upon application of an applied pressure above a predetermined threshold.
摘要翻译：公开了用于定制支架的洗脱速率的方法和设备。支架包括形成支架的中空支柱，中空支柱限定内腔空间，布置在中空支柱的腔空间内的药物制剂以及用于在体内洗脱药物制剂的至少一个侧端口， I>。当支架处于径向扩张构型时，中空支柱可从具有药物制剂的第一洗脱速率的第一构型变形成具有药物制剂的第二洗脱速率的第二构型。第二次洗脱速率比第一次洗脱速率快。在施加高于预定阈值的施加压力时，中空支柱从第一构型变形为第二构型。

3. 发明申请

WO2017214432A1 CUSTOMIZING THE ELUTION PROFILE OF A STENT 审中-公开
标题翻译：定制一个支架的选择简介
公开(公告)号：WO2017214432A1
公开(公告)日：2017-12-14
申请号：PCT/US2017/036604
申请日：2017-06-08
申请人： MEDTRONIC VASCULAR INC.
发明人： HOBBINS, David , O'DONOVAN, Conor , WOLLEY, Lana , NOLAN, Shane , SAYERS, Michael , KEANE, Eamon , DOWLING, Brian , COPE, Jonathan , ANDERSON, Marc , EGERTER, Risa
IPC分类号： A61F2/88 , A61F2/915
摘要： Methods and apparatus are disclosed for customizing an elution profile of a stent after manufacture of the stent has been completed. The stent includes a plurality of side ports for eluting a drug formulation within a lumenal space of a hollow strut that forms the stent. An effective diameter of at least one side port of the plurality of side ports of the stent is modified in order to customize an elution profile of the stent. In an embodiment hereof, the plurality of side ports are completely blocked or plugged with a filler material during the manufacture of the stent and at least a portion of the filler material is removed to increase an effective diameter of at least one side port of the plurality of side ports of the stent in order to customize an elution profile of the stent. In another embodiment hereof, the plurality of side ports are open following the manufacture of the stent and at least one side port of the plurality of side ports of the stent is at least partially filled with a filler material to decrease the effective diameter of the at least one side port in order to customize an elution profile of the stent. In another embodiment hereof, the stent is soaked within a liquid to remove at least a portion of the drug formulation from the lumenal space of the hollow strut to thereby customize an elution profile of the stent.
摘要翻译：公开了用于在支架制造完成后定制支架的洗脱轮廓的方法和设备。该支架包括多个侧孔，用于在形成支架的中空支柱的内腔空间内洗脱药物制剂。对支架的多个侧孔中的至少一个侧孔的有效直径进行修改以便定制支架的洗脱轮廓。在本发明的一个实施例中，在制造支架期间，多个侧孔被填充材料完全堵塞或堵塞，并且至少一部分填充材料被去除以增加多个侧孔中的至少一个侧孔的有效直径为了定制支架的洗脱曲线，支架侧孔的尺寸。在本发明的另一个实施例中，在制造支架之后，多个侧端口是开放的，并且支架的多个侧端口中的至少一个侧端口至少部分地填充有填充材料，以减小支架的有效直径至少一个侧端口以定制支架的洗脱轮廓。在本发明的另一个实施方案中，将支架浸入液体中以从中空支撑物的腔空间去除至少一部分药物制剂，从而定制支架的洗脱轮廓。

4. 发明授权

EP3219088B1 VISUAL AND TACTILE ASSESSMENT TOOL FOR ATTACHING TO A MOBILE DEVICE 有权
公开(公告)号：EP3219088B1
公开(公告)日：2019-02-20
申请号：EP15804250.7
申请日：2015-11-13
申请人： Medtronic Vascular, Inc.
发明人： O'CONNELL, Barry , DOWLING, Brian , SMEDLEY, James
IPC分类号： A61B5/00 , G02B25/00 , G02B25/02 , H04N5/225 , H04M1/21 , A61B5/02 , G06F1/16

5. 发明公开

EP3219088A1 VISUAL AND TACTILE ASSESSMENT TOOL FOR ATTACHING TO A MOBILE DEVICE 有权
标题翻译：视觉和触觉评估工具，用于连接移动设备
公开(公告)号：EP3219088A1
公开(公告)日：2017-09-20
申请号：EP15804250.7
申请日：2015-11-13
申请人： Medtronic Vascular, Inc.
发明人： O'CONNELL, Barry , DOWLING, Brian , SMEDLEY, James
IPC分类号： H04M1/21 , A61B5/02 , G06F1/16
CPC分类号： H04N5/2254 , A61B5/02007 , A61B5/7425 , G02B25/002 , G02B25/02 , G06F1/163 , G06F1/1632 , G06F1/1686 , H04M1/21
摘要： A selectively attachable and removable visual and tactile assessment tool or clip for use with a mobile device is provided. Clip is an elongate member forming a curvilinear shape having a magnifying lens at a distal end thereof. Clip has a transparent tubular member disposed between first and second openings through the body portion of the clip. Tubular member has varying internal diameters to simulate, for example, the constriction or stenosis of a patient's vessel lumen. Once clip is attached to mobile device and the magnifying lens is positioned over the camera of the mobile device, a catheter is inserted through tubular member. The magnifying lens enlarges the size of the catheter displayed on the screen of the mobile device.
摘要翻译：提供了与移动设备一起使用的可选择性连接和可移除的视觉和触觉评估工具或夹子。夹子是形成在其远端具有放大镜的曲线形状的细长构件。夹子具有透明的管状部件，其设置在夹子的主体部分的第一和第二开口之间。管状构件具有不同的内径以模拟例如患者血管内腔的狭窄或狭窄。一旦将夹子连接到移动设备并且将放大镜定位在移动设备的照相机上，则将导管插入穿过管状构件。放大镜扩大了移动设备屏幕上显示的导管的尺寸。

6. 发明授权

EP3468511B1 CUSTOMIZING THE ELUTION PROFILE OF A STENT 有权
公开(公告)号：EP3468511B1
公开(公告)日：2020-04-15
申请号：EP17731407.7
申请日：2017-06-08
申请人： Medtronic Vascular Inc.
发明人： HOBBINS, David , O'DONOVAN, Conor , WOLLEY, Lana , NOLAN, Shane , SAYERS, Michael , KEANE, Eamon , DOWLING, Brian , COPE, Jonathan , ANDERSON, Marc , EGERTER, Risa
IPC分类号： A61F2/88 , A61F2/915

7. 发明公开

EP3468511A1 CUSTOMIZING THE ELUTION PROFILE OF A STENT 有权
公开(公告)号：EP3468511A1
公开(公告)日：2019-04-17
申请号：EP17731407.7
申请日：2017-06-08
申请人： Medtronic Vascular Inc.
发明人： HOBBINS, David , O'DONOVAN, Conor , WOLLEY, Lana , NOLAN, Shane , SAYERS, Michael , KEANE, Eamon , DOWLING, Brian , COPE, Jonathan , ANDERSON, Marc , EGERTER, Risa
IPC分类号： A61F2/88 , A61F2/915
摘要： Methods and apparatus are disclosed for customizing an elution rate of a stent. The stent includes a hollow strut that forms the stent, the hollow strut defining a lumenal space, a drug formulation disposed within the lumenal space of the hollow strut, and at least one side port for eluting the drug formulation in vivo. When the stent is in the radially expanded configuration the hollow strut is deformable from a first configuration that has a first elution rate for the drug formulation to a second configuration that has a second elution rate for the drug formulation. The second elution rate is faster than the first elution rate. The hollow strut deforms from the first configuration to the second configuration upon application of an applied pressure above a predetermined threshold.

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