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1. 发明申请

WO2004103470B1 MEDICAL SYSTEM INCLUDING A NOVEL BIPOLAR PACING PAIR 审中-公开
标题翻译：医疗系统包括一个新的双极板对
公开(公告)号：WO2004103470B1
公开(公告)日：2005-06-02
申请号：PCT/US2004015152
申请日：2004-05-13
申请人： MEDTRONIC INC , BROWN MARK L , WARMAN EDUARDO N , GILLBERG JEFFREY M , BONNER MATTHEW D , MARSHALL MARK T , WHITMAN TERESA A
发明人： BROWN MARK L , WARMAN EDUARDO N , GILLBERG JEFFREY M , BONNER MATTHEW D , MARSHALL MARK T , WHITMAN TERESA A
IPC分类号： A61N1/05 , A61N1/368 , A61N1/37 , A61N1/39 , A61N1/00
CPC分类号： A61N1/057 , A61N1/0568 , A61N1/0573 , A61N1/368 , A61N1/3702 , A61N2001/0585
摘要： An implantable electrical medical system comprises a low voltage cathode electrode assembly, including a cathode surface adapted for intimate contact with electrically active tissue, and a low voltage anode electrode assembly, including an anode surface and a porous layer extending over the anode surface. The cathode surface and the anode surface function as a bipolar pair for pacing and the porous layer extending over the anode surface allows conduction therethrough and prevents the anode surface from contacting the electrically active tissue in order to prevent anodal stimulation.
摘要翻译：可植入电气医疗系统包括低压阴极电极组件，其包括适于与电活性组织紧密接触的阴极表面，以及包括阳极表面和在阳极表面上延伸的多孔层的低压阳极电极组件。阴极表面和阳极表面用作用于起搏的双极对，并且在阳极表面上延伸的多孔层允许通过其传导，并且防止阳极表面接触电活性组织以防止阳极刺激。

2. 发明申请

WO2013032624A2 HOLDING MEMBERS FOR IMPLANTABLE CARDIAC STIMULATION DEVICES 审中-公开
标题翻译：用于植入式心脏刺激装置的保持元件
公开(公告)号：WO2013032624A2
公开(公告)日：2013-03-07
申请号：PCT/US2012049264
申请日：2012-08-02
申请人： MEDTRONIC INC , BONNER MATTHEW D , ANDERSON THOMAS A , BERTHIAUME WILLIAM A , HURTIG NOELLE C
发明人： BONNER MATTHEW D , ANDERSON THOMAS A , BERTHIAUME WILLIAM A , HURTIG NOELLE C
IPC分类号： A61N1/372 , A61B17/34 , A61N1/05 , A61N1/375
CPC分类号： A61N1/37205 , A61N1/0573 , A61N1/362 , A61N1/3756
摘要： A holding member for an implantable cardiac device facilitates tether attachment and removal, at time of implant, and snaring, or otherwise capturing, for subsequent explant. Preferably located in proximity to a proximal end wall of a shell of the device, the holding member includes a strut portion, being spaced proximally apart from the proximal end wall, a waist portion, defining a recess, and an engagement section, extending between the strut portion and the waist portion and overhanging the recess. The waist portion may either extend between the strut portion and the proximal end wall, or be formed in the shell, distal to the proximal end wall. Alternately, the holding member includes a loop element and an engagement element coupled thereto, between first and second segments thereof. The segments are initially formed to give the loop element an opening, and have a flexibility to be compressed together.
摘要翻译：用于植入式心脏装置的保持构件有助于在植入时系绳附接和移除，并且为后续移植物捕捉或捕获。优选地，所述保持构件位于所述装置的壳体的近端壁附近，所述保持构件包括与所述近端壁向近侧间隔开的支柱部分，限定凹部的腰部部分和接合部分，支柱部分和腰部分并悬于凹陷处。腰部可以在支柱部分和近端壁之间延伸，或者可以在远离近端壁的外壳中形成。可选地，保持构件包括在其第一段和第二段之间联接的环元件和接合元件。这些部分最初形成为使得环元件具有开口，并且具有被压缩在一起的灵活性。

3. 发明专利

DE602005020500D1 未知
公开(公告)号：DE602005020500D1
公开(公告)日：2010-05-20
申请号：DE602005020500
申请日：2005-11-30
申请人： MEDTRONIC INC
发明人： BONNER MATTHEW D , ROTHSTEIN PAUL T , HINIDUMA-LOKUGE PRASANGA D , KEOGH JAMES R , USHER RAYMOND W , JAHNS SCOTT E , CHEN VICTOR T
IPC分类号： A61B17/34 , A61B17/00 , A61B17/20 , A61B17/28 , A61B17/30 , A61M5/00
摘要： Apparatus and methods for injecting biological agents into tissue. Devices are provided having elongate shafts and distal injection heads for driving needles into tissue and injecting medical agents into the tissue through the needles. A longitudinal force directed along the shaft can be translated to a needle driving force. Some devices provide controllably variable needle penetration depth. Devices include mechanical needle drivers utilizing four link pantographs, rack and pinions, and drive yokes for driving a first needle bearing body toward a second tissue contacting body. Other devices include inflatable members for driving and retracting needles. Still other devices include magnets for biasing the needles in extended and/or retracted positions. The invention includes minimally invasive methods for epicardially injecting cardiocyte precursor cells into infarct myocardial tissue.

4. 发明专利

AU7710198A Single pass lead and method of use 未知
公开(公告)号：AU7710198A
公开(公告)日：1999-03-22
申请号：AU7710198
申请日：1998-06-01
申请人： MEDTRONIC INC
发明人： WARMAN EDUARDO N , BONNER MATTHEW D
IPC分类号： A61N1/05

5. 发明专利

CA2525872A1 MEDICAL SYSTEM INCLUDING A NOVEL BIPOLAR PACING PAIR 未知
公开(公告)号：CA2525872A1
公开(公告)日：2004-12-02
申请号：CA2525872
申请日：2004-05-13
申请人： MEDTRONIC INC
发明人： BONNER MATTHEW D , MARSHALL MARK T , WHITMAN TERESA A , BROWN MARK L , GILLBERG JEFFREY M , WARMAN EDUARDO N
IPC分类号： A61N1/39 , A61N1/00 , A61N1/05 , A61N1/368 , A61N1/37
摘要： An implantable electrical medical system comprises a low voltage cathode electrode assembly, including a cathode surface adapted for intimate contact with electrically active tissue, and a low voltage anode electrode assembly, including an anode surface and a porous layer extending over the anode surface. The cathode surface and the anode surface function as a bipolar pai r for pacing and the porous layer extending over the anode surface allows conduction therethrough and prevents the anode surface from contacting the electrically active tissue in order to prevent anodal stimulation.

6. 发明专利

AU6557998A Medical lead connector system 未知
公开(公告)号：AU6557998A
公开(公告)日：1998-11-24
申请号：AU6557998
申请日：1998-03-16
申请人： MEDTRONIC INC
发明人： BISCHOFF THOMAS C , BONNER MATTHEW D , LASKE TIMOTHY G , RIES ANDREW J , SOMMER JOHN L
IPC分类号： A61N1/05 , A61N1/375 , H01R13/52

7. 发明申请

WO2004028613A3 METHOD AND APPARATUS FOR PROVIDING INTRA-PERICARDIAL ACCESS 审中-公开
标题翻译：用于提供局部心脏接入的方法和设备
公开(公告)号：WO2004028613A3
公开(公告)日：2004-07-29
申请号：PCT/US0330416
申请日：2003-09-25
申请人： MEDTRONIC INC
发明人： BONNER MATTHEW D , LASKE TIMOTHY G
IPC分类号： A61B17/00 , A61B17/22 , A61B17/34 , A61B18/14 , A61M25/04 , A61N1/05
CPC分类号： A61B17/3478 , A61B17/3417 , A61B18/1492 , A61B2017/00247 , A61B2017/22077 , A61B2017/3443 , A61B2017/3484 , A61B2017/3488 , A61B2017/349 , A61B2018/00291 , A61B2018/00357 , A61B2018/00392
摘要： A method and apparatus for accessing the pericardial space is provided for stable short term or long term placement of a delivery catheter or cannula having its distal-most end fixed on the endocardial surface such that a pericardial access device including a dilator and a puncturing device may be advanced through the myocardium into the pericardial space. The catheter is provided with a distal fixation member that maintains the catheter position over the myocardial hole created by the access device allowing various medical instruments to be passed through the hole into the pericardial space. Alternatively, the catheter may be positioned against the septal wall to access a left heart chamber via a right heart chamber.
摘要翻译：提供了一种用于进入心包空间的方法和设备，用于将其最远端固定在心内膜表面上的输送导管或套管的稳定的短期或长期放置，使得包括扩张器和穿刺装置的心包进入装置可以通过心肌进入心包空间。导管设置有远侧固定构件，该远侧固定构件将导管位置保持在由进入装置产生的心肌孔上，从而允许各种医疗器械穿过孔进入心包空间。或者，导管可以靠着隔膜壁定位以经右心室进入左心室。

8. 发明申请

WO2008048573A2 VESSEL TENSIONING HANDLE AND METHOD OF VESSEL HARVESTING 审中-公开
标题翻译：容器张紧手柄和容器收集方法
公开(公告)号：WO2008048573A2
公开(公告)日：2008-04-24
申请号：PCT/US2007022034
申请日：2007-10-16
申请人： MEDTRONIC INC
发明人： CLAGUE CYNTHIA T , HOBDAY MICHAEL J , USHER RAYMOND W , BRISCOE RODERICK E , JOLLY KATHERINE S , BUHR REBECCA A , OLIG CHRISTOPHER P , MEYER ERIC A , CHRISTIAN STEVEN C , DAIGLE THOMAS P , REETZ ROBERT H , SANDSTROM JEFFREY D , KEOGH JAMES R , BONNER MATTHEW D , JAHNS SCOTT E , HAARSTAD PHILIP J
IPC分类号： A61B17/3209
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a vessel tensioning handle and method of placing tension on a section of a vessel being harvested. The handle can include a housing, a bobbin assembly, a vessel tensioning tape, and a tensioning device member. The tensioning device member can be coupled to a cannula that is coupled to the vessel. The method can include using the vessel tensioning tape to place tension on the section of the vessel as the cutting device is advanced over the vessel.
摘要翻译：本发明的实施例提供了一种船只张紧手柄和将张力放置在正被收获的船只的一部分上的方法。手柄可以包括壳体，线轴组件，容器张紧带和张紧装置构件。张紧装置构件可联接到联接到血管的套管。该方法可以包括当切割装置在容器上前进时使用容器张紧带将张力放置在容器的部分上。

9. 发明申请

WO2008048572A2 CUTTING DEVICE AND METHOD OF VESSEL HARVESTING 审中-公开
标题翻译：切割装置和容器收获方法
公开(公告)号：WO2008048572A2
公开(公告)日：2008-04-24
申请号：PCT/US2007022033
申请日：2007-10-16
申请人： MEDTRONIC INC
发明人： CLAGUE CYNTHIA T , HOBDAY MICHAEL J , USHER RAYMOND W , BRISCOE RODERICK E , JOLLY KATHERINE S , BUHR REBECCA A , OLIG CHRISTOPHER P , MEYER ERIC A , CHRISTIAN STEVEN C , DAIGLE THOMAS P , REETZ ROBERT H , SANDSTROM JEFFREY D , KEOGH JAMES R , BONNER MATTHEW D , JAHNS SCOTT E , HAARSTAD PHILIP J
IPC分类号： A61B17/3209
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a cutting device and method of vessel harvesting. The cutting device can include at least one tubular member, a cutting element, and a centering member. The cutting device can include at least one tubular member with a flexible section and a cutting element. The method of vessel harvesting can include spacing a cutting element of the cutting device from the vessel as the cutting element is advanced over the vessel.
摘要翻译：本发明的实施例提供了一种切割装置和血管收获方法。切割装置可以包括至少一个管状构件，切割元件和定心构件。切割装置可以包括具有柔性部分和切割元件的至少一个管状部件。容器收获的方法可包括当切割元件在容器上前进时将切割装置的切割元件与容器隔开。

10. 发明申请

WO2004064646A8 METHODS AND APPARATUS FOR ACCESSING AND STABILIZING AN AREA OF THE HEART 审中-公开
标题翻译：用于访问和稳定心脏区域的方法和装置
公开(公告)号：WO2004064646A8
公开(公告)日：2007-03-08
申请号：PCT/US2004000468
申请日：2004-01-09
申请人： MEDTRONIC INC
发明人： BONNER MATTHEW D , CHEN VICTOR T , USHER RAYMOND W , KEOUGH JAMES R
IPC分类号： A61B18/14 , A61B19/00 , A61B19/02 , A61B19/08 , A61B19/10 , A61M1/00
CPC分类号： A61B18/1485 , A61B18/1402 , A61B46/00 , A61B46/23 , A61B50/20 , A61B2018/00291 , A61B2090/306 , A61B2090/3614 , A61B2218/007 , A61M1/008
摘要： A tubular suction tool (10) for accessing an anatomic surface or anatomic space and particularly the pericardium to access pericardial space and the epicardial surface of the heart to implant cardiac leads (96) in a minimally invasive manner are disclosed. The suction tool incorporates a suction pad concave wall (36) defining a suction cavity, a plurality of suction ports (42) arrayed about the concave wall, and a suction lumen, to form a bleb of tissue into the suction cavity when suction is applied. The suction cavity extends along one side of the suction pad, so that the suction pad and suction cavity can be applied tangentially against a tissue site. The suction tool can incorporate light emission (52) and video imaging (58) of tissue adjacent the suction pad. A working lumen (20) terminating in a working lumen port (46) into the suction cavity enables introduction of tools, cardiac leads, and other instruments, cells, drugs or materials into or through the tissue bleb drawn into the suction cavity.
摘要翻译：公开了一种用于访问解剖表面或解剖空间的管状抽吸工具（10），特别是用于进入心包空间的心包和心脏的心外膜表面以微创方式植入心脏引线（96）。抽吸工具包括限定吸入腔的吸盘凹壁（36），围绕凹壁排列的多个吸入口（42）和吸入腔，以在抽吸时形成吸入腔中的组织泡。吸入腔沿着吸盘的一侧延伸，使得吸力垫和抽吸腔可以相对于组织部位切向施加。吸入工具可以包括邻近吸盘的组织的光发射（52）和视频成像（58）。终止于进入吸入腔的工作管腔端口（46）的工作腔（20）能够将工具，心脏引线以及其它器械，细胞，药物或材料引入到吸入腔中的组织水泡中或穿过其中。

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