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1. 发明专利

CA2484193A1 COMBINED ANTI-TACHYCARDIA PACING (ATP) AND HIGH VOLTAGE THERAPY FOR TREATING VENTRICULAR ARRHYTHMIAS 未知
公开(公告)号：CA2484193A1
公开(公告)日：2003-11-13
申请号：CA2484193
申请日：2003-03-10
申请人： MEDTRONIC INC
发明人： OLSON WALTER H , SHARMA VINOD , KRAUSE PAUL G , KASZAS CAMERON J , PADMANABHAN VASANT , OUSDIGIAN KEVIN T , DEGROOT PAUL J
IPC分类号： A61N1/365 , A61N1/39
摘要： The present invention provides a system and method for treating an arrhythmi a of the heart. The system and method involves delivery of anti-tachy pacing (ATP) pulses to the heart, possibly followed by the delivery of a high-volta ge shock. ATP delivery is controlled such that the time of delivery of any high - voltage shock is not affected by the prior delivery of the ATP pulses. Syste m control may be accomplished using one or more programmable parameters, which may include a user-specified shock energy.

2. 发明专利

CA2489366A1 METHOD AND APPARATUS FOR PREVENTION OF ARRHYTHMIA CLUSTERS USING OVERDRIVE PACING 未知
公开(公告)号：CA2489366A1
公开(公告)日：2003-12-24
申请号：CA2489366
申请日：2003-06-13
申请人： MEDTRONIC INC
发明人： GEORGE WILLIAM J , MULLEN THOMAS J , PADMANABHAN VASANT , OLSON WALTER H , MEHRA RAHUL , ZHOU XIAOHONG
IPC分类号： A61B5/0402 , A61N1/362 , A61N1/37
摘要： An implantable medical device that includes a microprocessor that characterizes cardiac activity of apatient to enable the implantable medical device to deliver therapy in response to an identified arrhythmia event. A monitor/controller monitors the characterized cardiac activity and the delivered therapy, and controls activation of triggered overdrive pacing subsequent to the delivered therapy.

3. 发明专利

DE60319223T2 未知
公开(公告)号：DE60319223T2
公开(公告)日：2009-02-12
申请号：DE60319223
申请日：2003-06-13
申请人： MEDTRONIC INC
发明人： PADMANABHAN VASANT , OLSON WALTER H , MEHRA RAHUL , ZHOU XIAOHONG , MULLEN THOMAS J , GEORGE WILLIAM J
IPC分类号： A61B5/0402 , A61N1/37 , A61N1/362

4. 发明专利

DE60327622D1 未知
公开(公告)号：DE60327622D1
公开(公告)日：2009-06-25
申请号：DE60327622
申请日：2003-03-10
申请人： MEDTRONIC INC
发明人： OUSDIGIAN KEVIN T , PADMANABHAN VASANT , DEGROOT PAUL J , SHARMA VINOD , KASZAS CAMERON J , KRAUSE PAUL G , OLSON WALTER H
IPC分类号： A61N1/365 , A61N1/39
摘要： A system and method for treating an arrhythmia of the heart, involves delivery of anti-tachy pacing (ATP) pulses to the heart, possibly followed by the delivery of a high-voltage shock. ATP delivery is controlled such that the time delivery of any high-voltage shock is not affected by the prior delivery of the ATP pulses. System control may be accomplished using one or more programmable parameters, which may include a user-specified shock energy.

5. 发明专利

CA2529289A1 AUTOMATIC EGM AMPLITUDE MEASUREMENTS DURING TACHYARRHYTHMIA EPISODES 未知
公开(公告)号：CA2529289A1
公开(公告)日：2004-12-29
申请号：CA2529289
申请日：2004-06-18
申请人： MEDTRONIC INC
发明人： BRANDSTETTER JOHN S , PADMANABHAN VASANT
IPC分类号： A61N1/362 , A61B5/352 , A61B5/363 , A61N1/37
摘要： In an IMD (10), when tachyarrhythmia detection criterion are satisfied or a high intrinsic heart rate is detected, a peak amplitude detection circuit (186) is enabled to detect the peak amplitude of the cardiac signal of interest, i.e., the P-wave in the case of atrial tachyarrhythmias and the R- wave in case of ventricular tachyarrhythmias. Peak amplitude data is accumulated for subsequent use in setting sensing thresholds and/or gain of a sense amplifier (128) to reduce undersensing of lower amplitude cardiac signals during such tachyarrhythmias.

6. 发明专利

DE60319223D1 未知
公开(公告)号：DE60319223D1
公开(公告)日：2008-04-03
申请号：DE60319223
申请日：2003-06-13
申请人： MEDTRONIC INC
发明人： PADMANABHAN VASANT , OLSON WALTER H , MEHRA RAHUL , ZHOU XIAOHONG , MULLEN THOMAS J , GEORGE WILLIAM J
IPC分类号： A61B5/0402 , A61N1/37 , A61N1/362

7. 发明专利

DE60012895T2 未知
公开(公告)号：DE60012895T2
公开(公告)日：2005-08-25
申请号：DE60012895
申请日：2000-03-01
申请人： MEDTRONIC INC
发明人： PADMANABHAN VASANT , OLSON H
IPC分类号： A61N1/37 , A61N1/39
摘要： An implantable monitoring device for monitoring a patient's heart rate variability over time. The device includes a cardiac electrogram amplifier, a sensing electrode coupled to an input of the amplifier, timing circuitry, processing circutry and a memory. The timing circuitry defines successive monitoring periods each extending over a period of hours, the monitoring periods together extending at least over a period of weeks and also defines successive shorter time periods during each monitoring period. The memory stores heart intervals between depolarizations of the patient's heart sensed by the amplifier during the shorter time periods. The processing circuitry calculates median intervals between depolarizations of the patient's heart sensed by the amplifier during the shorter time periods and calculates standard deviations of the median intervals calculated during each monitoring period. The processing circuitry may also reject heart intervals occurring during tachyarrhythmias and calculate median intervals based only on heart intervals not rejected.

8. 发明专利

DE60012895D1 未知
公开(公告)号：DE60012895D1
公开(公告)日：2004-09-16
申请号：DE60012895
申请日：2000-03-01
申请人： MEDTRONIC INC
发明人： PADMANABHAN VASANT , OLSON H
IPC分类号： A61N1/37 , A61N1/39
摘要： An implantable monitoring device for monitoring a patient's heart rate variability over time. The device includes a cardiac electrogram amplifier, a sensing electrode coupled to an input of the amplifier, timing circuitry, processing circutry and a memory. The timing circuitry defines successive monitoring periods each extending over a period of hours, the monitoring periods together extending at least over a period of weeks and also defines successive shorter time periods during each monitoring period. The memory stores heart intervals between depolarizations of the patient's heart sensed by the amplifier during the shorter time periods. The processing circuitry calculates median intervals between depolarizations of the patient's heart sensed by the amplifier during the shorter time periods and calculates standard deviations of the median intervals calculated during each monitoring period. The processing circuitry may also reject heart intervals occurring during tachyarrhythmias and calculate median intervals based only on heart intervals not rejected.

9. 发明专利

CA2454235A1 METHOD AND APPARATUS TO CONTROL DELIVERY OF HIGH-VOLTAGE ANDANTI-TACHY PACING THERAPY IN AN IMPLANTABLE MEDICAL DEVICE 未知
公开(公告)号：CA2454235A1
公开(公告)日：2003-02-13
申请号：CA2454235
申请日：2002-07-25
申请人： MEDTRONIC INC
发明人： PADMANABHAN VASANT , SHARMA VINOD , KRAUSE PAUL G , OUSDIGIAN KEVIN T , DEGROOT PAUL J
IPC分类号： A61N1/365 , A61N1/39 , A61N1/362
摘要： A system and method for delivering both anti-tachy pacing (ATP) therapy and high-voltage shock therapy in response to detection of abnormal cardiac rhythms is disclosed. The system controls the time between delivering ATP therapy and the charging of high-voltage capacitors in preparation for shock delivery based on a predetermined set of criteria. In one embodiment, the inventive system operates in an ATP during Capacitor Charging (ATP-DCC) mode wherein all, or substantially all, of the ATP therapy is delivered during charging of the high-voltage capacitors. Based on evaluation of the predetermined set of criteria, the system may switch to an additional ATP before Capacitor Charging (ATP-BCC) mode, wherein substantially all of the A TP therapy is delivered prior to charging of the high-voltage capacitor. According to one aspect of the invention, the predetermined set of criteria is based, at least in part, on the effectiveness of previously-delivered ATP therapy.

10. 发明申请

WO0170331A3 METHOD AND APPARATUS FOR MONITORING PHYSIOLOGIC PARAMETERS IN CONJUNCTION WITH A TREATMENT REGIMEN 审中-公开
标题翻译：用于监测与治疗方案相关的生理参数的方法和装置
公开(公告)号：WO0170331A3
公开(公告)日：2002-03-14
申请号：PCT/US0106898
申请日：2001-03-02
申请人： MEDTRONIC INC
发明人： OUSDIGIAN KEVIN T , STONE KAREN A , PADMANABHAN VASANT
IPC分类号： A61N1/372
CPC分类号： A61N1/37247
摘要： A system including an implantable medical device and an associated external device, in which the implantable device is adapted to monitor a physiologic parameter and includes a telemetry system for transmitting information to and receiving information from the external device, including information regarding the measured physiological parameter and in which wherein the external device includes a telemetry system for receiving information from the implanted device and for transmitting information to the implanted device and is provided with a mechanism for receiving information indicative of occurences of significant therapeutic events and is further provided with a display system which combines information received from the implantable device related to the monitored physiologic parameter with the information of therapeutic significance and for displays the combined information in a time-scaled display in which the measured physiologic parameter is displayed along a common time scale with indications of occurences of the significant therapy related events. The implantable device may also include a mechanism for delivering a therapy; and the mechanism in the external device for receiving information indicative of occurrences of significant therapeutic events may receive information regarding changes in the therapy delivered by the implantable device. The mechanism in the external device for receiving information indicative of occurrences of significant therapeutic events may also or in addition receive information indicative of changes in the therapy delivered by a physician, e.g. changes in a drug therapy.
摘要翻译：一种包括可植入医疗装置和相关联的外部装置的系统，其中所述可植入装置适于监测生理参数，并且包括用于向所述外部装置发送信息并从外部装置接收信息的遥测系统，所述遥测系统包括关于所测量的生理参数的信息，其中所述外部设备包括用于从所述植入设备接收信息并用于向所述植入设备发送信息的遥测系统，并且设置有用于接收指示重要治疗事件发生的信息的机构，并且还设置有显示系统，所述显示系统将从与所监视的生理参数相关的可植入装置接收到的信息与具有治疗意义的信息相结合，并且以按照公共时间标度w显示测量的生理参数的时间尺度显示中显示组合信息明显的治疗相关事件发生的迹象。可植入装置还可以包括用于递送治疗的机构; 并且用于接收指示重大治疗事件发生的信息的外部设备中的机制可以接收关于由可植入装置递送的治疗变化的信息。用于接收指示重大治疗事件发生的信息的外部设备中的机制还可以或另外接收指示由医师传递的治疗变化的信息，例如，药物治疗的变化。

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