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1. 发明申请

WO2012106100A3 MULTI FREQUENCY AND MULTI POLARITY COMPLEX IMPEDANCE MEASUREMENTS TO ASSESS ABLATION LESIONS 审中-公开
标题翻译：多频和多极性复合阻抗测量来评估消除距离
公开(公告)号：WO2012106100A3
公开(公告)日：2012-09-20
申请号：PCT/US2012021478
申请日：2012-01-17
申请人： MEDTRONIC ABLATION FRONTIERS , SHERMAN MARSHALL L , CONDIE CATHERINE R , STEWART MARK T
发明人： SHERMAN MARSHALL L , CONDIE CATHERINE R , STEWART MARK T
IPC分类号： A61B18/12 , A61B18/00
CPC分类号： A61B5/0531 , A61B5/0536 , A61B5/4848 , A61B5/7246 , A61B18/02 , A61B18/12 , A61B18/1492 , A61B2017/00128 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00279 , A61B2018/00285 , A61B2018/00404 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00666 , A61B2018/00869 , A61B2018/00875 , A61B2018/0212
摘要： A method of assessing a tissue ablation treatment, including positioning a medical device adjacent a target tissue; the medical device measuring a first impedance magnitude at a first frequency with the medical device; measuring a first impedance phase at a second frequency with the medical device; ablating at least a portion of the target tissue with the medical device; measuring at second impedance magnitude at a third frequency with the medical device; measuring a second impedance phase at a fourth frequency with the medical device; comparing at least one of (i) the first and second impedance magnitudes and (ii) the first and second impedance phases; and providing an indication of the efficacy of the ablation treatment based at least in part on the comparison.
摘要翻译：一种评估组织消融治疗的方法，包括定位邻近靶组织的医疗装置; 所述医疗设备用所述医疗设备测量第一频率的第一阻抗幅度; 用所述医疗装置测量第二频率的第一阻抗相位; 用医疗装置切除目标组织的至少一部分; 以医疗装置在第三频率的第二阻抗幅度下测量; 用所述医疗装置测量第四频率的第二阻抗相位; 比较（i）第一和第二阻抗幅度和（ii）第一和第二阻抗相位中的至少一个; 以及至少部分地基于比较来提供消融治疗的功效的指示。

2. 发明专利

CA2842350C MESH-OVERLAYED ABLATION AND MAPPING DEVICE 未知
公开(公告)号：CA2842350C
公开(公告)日：2016-10-11
申请号：CA2842350
申请日：2012-07-12
申请人： MEDTRONIC ABLATION FRONTIERS
发明人： STEWART MARK T , HONECK JORDON D
IPC分类号： A61B18/02 , A61B18/14
摘要： A medical system, including a catheter body, an elongate body disposed in the catheter body; an expandable element having a proximal portion coupled to the catheter body and a distal portion coupled to the elongate body, the distal portion of the expandable element defining the distal-most portion of the medical device; a mesh or array of longitudinal splines substantially surrounding the expandable element, at least a portion of the mesh or splines being electrically conductive; and a coolant source in fluid communication with the expandable element.

3. 发明专利

CA2842350A1 MESH-OVERLAYED ABLATION AND MAPPING DEVICE 未知
公开(公告)号：CA2842350A1
公开(公告)日：2013-02-07
申请号：CA2842350
申请日：2012-07-12
申请人： MEDTRONIC ABLATION FRONTIERS
发明人： STEWART MARK T , HONECK JORDON D
IPC分类号： A61B18/02 , A61B18/14
摘要： A medical system, including a catheter body, an elongate body disposed in the catheter body; an expandable element having a proximal portion coupled to the catheter body and a distal portion coupled to the elongate body, the distal portion of the expandable element defining the distal-most portion of the medical device; a mesh or array of longitudinal splines substantially surrounding the expandable element, at least a portion of the mesh or splines being electrically conductive; and a coolant source in fluid communication with the expandable element.

4. 发明申请

WO2007140331A3 METHODS OF USING HIGH INTENSITY FOCUSED ULTRASOUND TO FORM AN ABLATED TISSUE AREA CONTAINING A PLURALITY OF LESIONS 审中-公开
标题翻译：使用高强度聚焦超声波形成包含多种淋巴结的组织组织的方法
公开(公告)号：WO2007140331A3
公开(公告)日：2008-01-17
申请号：PCT/US2007069789
申请日：2007-05-25
申请人： MEDTRONIC INC , STEWART MARK T , FRANCISCHELLI DAVID E , KEOGH JAMES R , HISSONG JAMES B , SKARDA JAMES R , LEE HOTAIK , SMITH NADINE B
发明人： STEWART MARK T , FRANCISCHELLI DAVID E , KEOGH JAMES R , HISSONG JAMES B , SKARDA JAMES R , LEE HOTAIK , SMITH NADINE B
IPC分类号： A61N7/02
CPC分类号： A61B17/320068 , A61B8/4281 , A61B34/20 , A61B2017/320076 , A61B2017/320078 , A61B2018/00291 , A61B2034/2051 , A61B2090/378 , A61B2090/3782 , A61N7/02 , A61N7/022 , A61N2007/0078
摘要： A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.
摘要翻译：公开了一种用于消融组织的装置和方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，在跟踪患者内的消融部件的位置的同时引导患者内的消融部件，定位消融成员在消融组织的期望位置，从烧蚀构件发出消融能量以形成消融的组织区域，并从患者身上移除消融部件。

5. 发明申请

WO2007067945A8 METHOD FOR GUIDING A MEDICAL DEVICE 审中-公开
标题翻译：用于指导医疗设备的方法
公开(公告)号：WO2007067945A8
公开(公告)日：2009-08-20
申请号：PCT/US2006061722
申请日：2006-12-07
申请人： MEDTRONIC INC , FRANCISCHELLI DAVID E , HISSONG JAMES B , KEOGH JAMES R , SKARDA JAMES R , STEWART MARK T
发明人： FRANCISCHELLI DAVID E , HISSONG JAMES B , KEOGH JAMES R , SKARDA JAMES R , STEWART MARK T
IPC分类号： A61N7/02
CPC分类号： A61N7/02 , A61B8/4272 , A61B18/1442 , A61B34/20 , A61B2017/00243 , A61B2018/00291 , A61B2034/2051 , A61B2034/2053 , A61B2034/2063 , A61B2090/378 , A61B2090/397 , A61N7/022 , A61N2007/0078

6. 发明申请

WO2011094073A4 NEEDLE DESIGN FOR RECORDING MONOPHASIC ACTION POTENTIAL AND DELIVERY OF THERAPY 审中-公开
标题翻译：用于记录单因素行动的针头设计和治疗的递送
公开(公告)号：WO2011094073A4
公开(公告)日：2012-01-19
申请号：PCT/US2011021227
申请日：2011-01-14
申请人： MEDTRONIC INC , URBAN JON F , SHARMA VINOD , STEWART MARK T
发明人： URBAN JON F , SHARMA VINOD , STEWART MARK T
IPC分类号： A61N1/05 , A61B17/00 , A61M25/00
CPC分类号： A61N1/0575 , A61B5/042 , A61B5/6848 , A61B5/6852 , A61B2017/00053 , A61M25/0084 , A61M2025/0089 , A61M2025/0091
摘要： A system and associated method measure monophasic action potential signals for identifying a targeted tissue location and delivering a therapy to the targeted tissue location. The system includes a hollow needle having a sharpened distal tip, a first electrode at the distal tip and a fluid delivery lumen extending through the needle from a proximal needle end to an opening in the sharpened distal tip.
摘要翻译：系统和相关联的方法测量用于识别目标组织位置并将治疗递送到目标组织位置的单相动作电位信号。该系统包括具有锐化的远端尖端的中空针头，远侧末端处的第一电极和从近端针端延伸穿过尖锐远端的开口的流体输送腔。

7. 发明申请

WO0027469A3 EXTRACTABLE IMPLANTABLE MEDICAL LEAD 审中-公开
标题翻译：可提取的可植入医疗领域
公开(公告)号：WO0027469A3
公开(公告)日：2000-08-31
申请号：PCT/US9926111
申请日：1999-11-04
申请人： MEDTRONIC INC , SHOBERG BRET R , PADGETT CLARE E , LASKE TIMOTHY G , WALDHAUSER STEVEN L , STEWART MARK T , TAYLOR CATHERINE E , KEENEY KENNETH W , MARSHALL MARK T
发明人： SHOBERG BRET R , PADGETT CLARE E , LASKE TIMOTHY G , WALDHAUSER STEVEN L , STEWART MARK T , TAYLOR CATHERINE E , KEENEY KENNETH W , MARSHALL MARK T
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0563
摘要： A medical electrical lead provided with a generally isodiametric lead body. The lead body includes a first elongated plastic tube and an elongated conductor mounted in the first plastic tube. A first coil electrode is mounted exterior to and around the outer surface of the first tube and is coupled to the conductor. A second elongated plastic tube having an outer diameter approximately equal to the outer diameter of the first coil electrode, is mounted exterior to and around the outer surface of the first tube adjacent the first coil electrode and extends proximally therefrom. A second coil electrode having an outer diameter approximately equal to the outer diameter of the first coil electrode may be mounted exterior to and around the first tube proximal to the first coil electrode such that the second elongated plastic tube extends to a point adjacent the second coil electrode. A third elongated plastic tube having an outer diameter approximately equal to the outer diameter of the second coil electrode may be mounted exterior to the first tube adjacent the second coil electrode and extending proximally therefrom. In a preferred embodiment, the first tube is an extruded multi-lumen tube.
摘要翻译：一个医用电线，带有一个大致等面积的铅体。引线体包括第一细长塑料管和安装在第一塑料管中的细长导体。第一线圈电极安装在第一管的外表面之外并且围绕第一管的外表面并且连接到导体。具有大致等于第一线圈电极的外径的外径的第二细长塑料管被安装在与第一线圈电极相邻并在其周围的第一管的外表面的外部和周围，并从其向近侧延伸。具有大致等于第一线圈电极的外径的外径的第二线圈电极可以安装在靠近第一线圈电极的第一管的外部和周围，使得第二细长塑料管延伸到与第二线圈相邻的点电极。具有大致等于第二线圈电极的外径的外径的第三细长塑料管可以安装在邻近第二线圈电极的第一管的外部并且从其向近侧延伸。在优选实施例中，第一管是挤出的多腔管。

8. 发明申请

WO2004100813A3 MULTI-PURPOSE CATHETER APPARATUS AND METHOD OF USE 审中-公开
标题翻译：多用途导管装置及其使用方法
公开(公告)号：WO2004100813A3
公开(公告)日：2005-01-06
申请号：PCT/US2004014224
申请日：2004-05-07
申请人： MEDTRONIC INC , STEWART MARK T , FIEDLER GARY R , SANDSTONE JEFFREY D
发明人： STEWART MARK T , FIEDLER GARY R , SANDSTONE JEFFREY D
IPC分类号： A61B10/00 , A61B10/02 , A61B18/00 , A61B18/14
CPC分类号： A61B18/1492 , A61B10/0233 , A61B2018/00011 , A61B2018/1407 , A61B2018/1435 , A61B2218/002
摘要： According to the present invention, a catheter having at least one multi-purpose lumen formed through the catheter terminates proximal a relatively complex-shaped distal portion thereof. In one form of this embodiment, the relatively complex-shaped distal portion comprises a looped portion having diagnostic- and/or ablation-type electrodes coupled thereto and an elongated diameter-adjusting member coupled proximal the distal end of the looped portion. The multi-purpose lumen may be used to alternately accommodate a variety of dedicated materials; such as, (i) a guide wire for initial deployment or later repositioning of the catheter, (ii) a volume or flow of a contrast media and the like, (iii) a deployable hollow needle or tube and the like used to biopsy adjacent tissue or dispense a therapeutic agent into a volume of tissue, and (iv) a cooling fluid, such as saline solution and the like dispensed at least during therapeutic tissue ablation procedures.
摘要翻译：根据本发明，具有通过导管形成的至少一个多用途腔的导管终止于其相对复杂形状的远端部分的近端。在该实施例的一种形式中，相对复杂形状的远侧部分包括具有耦合到其上的诊断和/或消融型电极的环形部分和在环形部分的远端附近耦合的细长直径调节构件。多用途腔可用于交替容纳各种专用材料; 例如，（i）用于初始部署或稍后重新定位导管的导丝，（ii）造影剂等的体积或流动，（iii）用于活检相邻的可展开的空心针或管等组织或将治疗剂分配到一定体积的组织中，和（iv）至少在治疗性组织消融过程期间分配的冷却液，例如盐水溶液等。

9. 发明申请

WO2011094073A3 NEEDLE DESIGN FOR RECORDING MONOPHASIC ACTION POTENTIAL AND DELIVERY OF THERAPY 审中-公开
标题翻译：旨在记录单一疗法潜力和治疗方法的药物设计
公开(公告)号：WO2011094073A3
公开(公告)日：2011-11-24
申请号：PCT/US2011021227
申请日：2011-01-14
申请人： MEDTRONIC INC , URBAN JON F , SHARMA VINOD , STEWART MARK T
发明人： URBAN JON F , SHARMA VINOD , STEWART MARK T
IPC分类号： A61N1/05 , A61B17/00 , A61M25/00
CPC分类号： A61N1/0575 , A61B5/042 , A61B5/6848 , A61B5/6852 , A61B2017/00053 , A61M25/0084 , A61M2025/0089 , A61M2025/0091
摘要： A system and associated method measure monophasic action potential signals for identifying a targeted tissue location and delivering a therapy to the targeted tissue location. The system includes a hollow needle having a sharpened distal tip, a first electrode at the distal tip and a fluid delivery lumen extending through the needle from a proximal needle end to an opening in the sharpened distal tip.
摘要翻译：系统和相关方法测量单相动作电位信号，用于识别目标组织位置并向目标组织位置递送治疗。该系统包括具有尖锐远侧尖端的中空针头，位于远侧尖端处的第一电极以及从近侧针头延伸穿过针头到达尖锐远侧尖端中的开口的流体递送内腔。

10. 发明申请

WO2009140359A2 TISSUE LESION EVALUATION 审中-公开
标题翻译：组织评估
公开(公告)号：WO2009140359A2
公开(公告)日：2009-11-19
申请号：PCT/US2009043751
申请日：2009-05-13
申请人： MEDTRONIC INC , STEWART MARK T , FRANCISCHELLI DAVID E , HONG JINBACK
发明人： STEWART MARK T , FRANCISCHELLI DAVID E , HONG JINBACK
IPC分类号： A61B18/14
CPC分类号： A61B18/1445 , A61B2018/00029 , A61B2018/00065 , A61B2018/00113 , A61B2018/0016 , A61B2018/00357 , A61B2018/00363 , A61B2018/00577 , A61B2018/00839 , A61B2018/1472 , A61B2090/064 , A61B2218/002
摘要： Device, system and method for ablating tissue of a heart of a patient. The tissue is clamped between a pair of opposing jaws. A portion of the tissue is ablated at a first generally linear position on the tissue by applying ablative energy to two of a plurality of elongate electrodes, each of the two of the plurality of elongate electrodes being coupled in opposing relationship to each other and the pair of opposing jaws, respectively. An effectiveness of the ablation is sensed at a second generally linear position on the tissue with at least one of the plurality of elongate electrodes positioned on one of the pair of opposing jaws. The second linear position on the tissue is laterally distal to the first linear position on the tissue with respect to the atrium of the heart.
摘要翻译：用于消除患者心脏的组织的装置，系统和方法。将组织夹在一对相对的夹爪之间。通过向多个细长电极中的两个施加烧蚀能量，组织的一部分在组织上的第一大致线性位置被消融，多个细长电极中的每一个彼此相对地相互耦合，并且该对的对颚分别。在组织上的第二大致直线位置处感测消融的有效性，其中多个细长电极中的至少一个位于一对相对的夹爪中的一个上。组织上的第二线性位置相对于心脏的心房横向远离组织上的第一线性位置。

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