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1. 发明申请

WO2008094818A2 SYSTEM AND METHOD FOR ISCHEMIA CLASSIFICATION WITH IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：具有可植入医疗器械的ISCHEMIA分类的系统和方法
公开(公告)号：WO2008094818A2
公开(公告)日：2008-08-07
申请号：PCT/US2008/051981
申请日：2008-01-25
申请人： MEDTRONIC, INC. , SONG, Zhendong , LU, Steven Ning , MUSLEY, Shailesh Kumar V. , WARMAN, Eduardo N.
发明人： SONG, Zhendong , LU, Steven Ning , MUSLEY, Shailesh Kumar V. , WARMAN, Eduardo N.
IPC分类号： A61B5/0452
CPC分类号： A61B5/0452 , A61B5/7264 , Y10S128/92 , Y10S128/923
摘要： An implantable medical device monitors ST segment data collected from EGM. ST trends are established and monitored over time. The IMD is able to discern whether the data indicate supply ischemia, demand ischemia, or other physiological causes. The IMD is then able to provide appropriate information and alerts.
摘要翻译：可植入医疗器械监测从EGM收集的ST段数据。随着时间的推移建立和监测ST趋势。 IMD能够辨别数据是否表明供血缺血，需求缺血或其他生理原因。 IMD然后能够提供适当的信息和警报。

2. 发明申请

WO2008094895A1 APPARATUS FOR ISCHEMIA CLASSIFICATION WITH IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于具有可植入医疗装置的ISCHEMIA分类的装置
公开(公告)号：WO2008094895A1
公开(公告)日：2008-08-07
申请号：PCT/US2008/052287
申请日：2008-01-29
申请人： MEDTRONIC, INC. , SONG, Zhendong , LU, Steven Ning , SONG, Zhendong , LU, Steven Ning
发明人： SONG, Zhendong , LU, Steven Ning , SONG, Zhendong , LU, Steven Ning
IPC分类号： A61B5/0452
CPC分类号： A61B5/0006 , A61B5/0452 , A61B5/0468 , A61B5/7264 , A61N1/3627 , A61N1/36542
摘要： An implantable medical device monitors ST segment data collected from EGM. ST trends are established and monitored over time. The IMD is able to discern whether the data indicate supply ischemia, demand ischemia, or other physiological causes. The IMD is then able to provide appropriate information and alerts.
摘要翻译：可植入医疗器械监测从EGM收集的ST段数据。随着时间的推移建立和监测ST趋势。 IMD能够辨别数据是否表明供血缺血，需求缺血或其他生理原因。 IMD然后能够提供适当的信息和警报。

3. 发明申请

WO2013033296A1 METHOD AND APPARATUS FOR MONITORING CARDIAC AND RESPIRATORY CONDITIONS USING ACOUSTIC SOUNDS 审中-公开
标题翻译：使用声音监测心脏和呼吸道条件的方法和装置
公开(公告)号：WO2013033296A1
公开(公告)日：2013-03-07
申请号：PCT/US2012/052985
申请日：2012-08-30
申请人： MEDTRONIC, INC. , SONG, Zhendong , ZHOU, Xiaohong
发明人： SONG, Zhendong , ZHOU, Xiaohong
IPC分类号： A61B7/00 , A61B5/0205 , A61B5/08 , A61N1/36
CPC分类号： A61B7/003 , A61B5/0205 , A61B5/0826 , A61N1/3627 , A61N1/36514
摘要： A medical device system and associated method discriminate respiratory and cardiac conditions using respiratory sounds. A sensing module acquires a first signal and a second signal, at least the second signal acquired from an acoustic transducer. A processor is configured to receive the first signal and to control the sensing module to acquire the second acoustic signal in response to a change in the first signal. The processor discriminates between a cardiac condition and a respiratory condition as a cause of the change in the first signal in response to the second acoustic signal.
摘要翻译：医疗设备系统和相关方法使用呼吸音来辨别呼吸和心脏病状。感测模块至少从声换能器获取的第二信号获取第一信号和第二信号。处理器被配置为接收第一信号并且响应于第一信号的改变来控制感测模块获取第二声信号。处理器根据第二声信号，将心脏状况与呼吸状况鉴别为第一信号的变化的原因。

4. 发明申请

WO2012057852A1 ISCHEMIA DETECTION AND CLASSIFICATION 审中-公开
标题翻译： ISCHEMIA检测和分类
公开(公告)号：WO2012057852A1
公开(公告)日：2012-05-03
申请号：PCT/US2011/033811
申请日：2011-04-25
申请人： MEDTRONIC, INC. , SONG, Zhendong , STADLER, Robert, W.
发明人： SONG, Zhendong , STADLER, Robert, W.
IPC分类号： A61B5/0452 , A61B5/0245
CPC分类号： A61B5/0452 , A61B5/0245 , A61B5/1118
摘要： Techniques for detecting ischemia and classifying a type of ischemia are described. Electrograms of cardiac activity may be generated using implanted or external electrodes, e.g., electrodes carried on vascular leads within the heart and a housing electrode. In some examples, ischemia is detected and classified as benign or malignant based on whether a change an electrogram metric is detected, or first detected, in an endocardial electrogram or a non-endocardial electrogram. The relative timing of the change in the electrogram metric and a change in heart rate or patient activity may also be considered. In some examples, the system may create a stress test for detecting ischemia by instructing the patient to exercise or increasing the cardiac pacing rate.
摘要翻译：描述了用于检测缺血和分类一种缺血的技术。可以使用植入或外部电极（例如，在心脏内的血管引线上承载的电极和外壳电极）产生心脏活动的电描记图。在一些实例中，基于在心内膜电图或非心内膜电图中是否检测到或者首先检测到电描记图量度，检测到缺血并将其分类为良性或恶性。也可以考虑电描记图度量的变化和心率或患者活动变化的相对时间。在一些实例中，系统可以通过指示患者运动或增加心脏起搏速率来产生用于检测缺血的压力测试。

5. 发明申请

WO2010011632A1 VIRTUAL PHYSICIAN ACUTE MYOCARDIAL INFARCTION DETECTION SYSTEM AND METHOD 审中-公开
标题翻译：虚拟医学急性心肌梗死检测系统及方法
公开(公告)号：WO2010011632A1
公开(公告)日：2010-01-28
申请号：PCT/US2009/051220
申请日：2009-07-21
申请人： MEDTRONIC, INC. , WENGREEN, Eric, J. , SONG, Zhendong , LEE, Brian, B.
发明人： WENGREEN, Eric, J. , SONG, Zhendong , LEE, Brian, B.
IPC分类号： A61B5/00
CPC分类号： A61B5/0002 , A61B5/0006 , A61B5/0031 , A61B5/02405 , A61B5/0404 , A61B5/0452 , A61B5/04525 , A61B5/076 , A61N1/365
摘要： A system and method for virtually detecting a medical condition, such as acute myocardial infarction (AMI), in a patient using holistic diagnostic procedures implemented in medical devices. Physiological parameters in a patient are monitored in an implantable medical device (IMD) to detect deviations from desired characteristics. When severe physiological parameter deviations exist indicating with a desired certainty that the patient is experiencing a medical condition (e.g., AMI), an alert is generated. If only minor deviations from the desired characteristics exist, additional holistic diagnostic procedures are performed virtually for diagnosing whether the patient is likely to be experiencing the medical condition, such as querying the patient through an external device regarding symptoms the patient is experiencing and analyzing the patient's responses to the questions to determine whether the patient is experiencing the medical condition. When diagnosis is still unclear, additional holistic diagnostic procedures can be performed virtually until diagnosis is certain.
摘要翻译：用于使用在医疗装置中实施的整体诊断程序来虚拟检测医疗状况的系统和方法，例如急性心肌梗塞（AMI）。在可植入医疗器械（IMD）中监测患者的生理参数，以检测与所需特征的偏差。当存在严重的生理参数偏差，指示患者正在经历医疗状况（例如，AMI）的期望确定性时，产生警报。如果仅存在与期望特征的微小偏差，则虚拟地执行附加的整体诊断程序，用于诊断患者是否可能经历医疗状况，例如通过外部设备查询患者所遇到的症状并分析患者的回答问题以确定患者是否正在经历医疗状况。当诊断仍不清楚时，可以进行额外的整体诊断程序，直到诊断确定为止。

6. 发明申请

WO2020023839A1 FLUID STATUS DETECTION FROM A CARDIAC ELECTRICAL SIGNAL AND AN IMPEDANCE SIGNAL 审中-公开
公开(公告)号：WO2020023839A1
公开(公告)日：2020-01-30
申请号：PCT/US2019/043597
申请日：2019-07-26
申请人： MEDTRONIC, INC.
发明人： SONG, Zhendong , ZIELINSKI, Todd M. , LEE, Brian B.
IPC分类号： A61B5/053 , A61B5/0456 , A61B5/11 , A61B5/00
摘要： A medical device is configured to generate fluid status signal data of a patient by determining impedance metrics from an impedance signal, determining cardiac electrical signal amplitudes from a cardiac electrical signal and determining a calibration relationship between the impedance metrics and cardiac electrical signal amplitudes. The medical device generates a fluid status signal data by adjusting cardiac electrical signal amplitudes according to the determined calibration relationship. The fluid status signal data may be displayed or monitored for detecting a change in the patient's fluid status.

7. 发明公开

EP3829431A1 FLUID STATUS DETECTION FROM A CARDIAC ELECTRICAL SIGNAL AND AN IMPEDANCE SIGNAL 审中-公开
公开(公告)号：EP3829431A1
公开(公告)日：2021-06-09
申请号：EP19756276.2
申请日：2019-07-26
申请人： Medtronic, Inc
发明人： SONG, Zhendong , ZIELINSKI, Todd M. , LEE, Brian B.
IPC分类号： A61B5/053 , A61B5/0456 , A61B5/11 , A61B5/00

8. 发明公开

EP2111155A2 SYSTEM AND METHOD FOR ISCHEMIA CLASSIFICATION WITH IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：系统和方法分类缺血再植入式医疗设备
公开(公告)号：EP2111155A2
公开(公告)日：2009-10-28
申请号：EP08728243.0
申请日：2008-01-25
申请人： MEDTRONIC, INC.
发明人： SONG, Zhendong , LU, Steven Ning , MUSLEY, Shailesh Kumar V. , WARMAN, Eduardo N.
IPC分类号： A61B5/0452
CPC分类号： A61B5/0452 , A61B5/7264 , Y10S128/92 , Y10S128/923
摘要： An implantable medical device monitors ST segment data collected from EGM. ST trends are established and monitored over time. The IMD is able to discern whether the data indicate supply ischemia, demand ischemia, or other physiological causes. The IMD is then able to provide appropriate information and alerts.

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