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1. 发明申请

WO2008137539A1 METHOD AND APPARATUS FOR DETECTING ARRHYTHMIAS IN A MEDICAL DEVICE 审中-公开
标题翻译：用于检测医疗器械中的ARRHYTHMIAS的方法和装置
公开(公告)号：WO2008137539A1
公开(公告)日：2008-11-13
申请号：PCT/US2008/062206
申请日：2008-05-01
申请人： MEDTRONIC, INC. , GHANEM, Raja N. , STADLER, Robert W. , ZHANG, Xusheng , KLECKNER, Karin J. , KRAUSE, Paul, G. , KRAUSE, Paul, G.
发明人： GHANEM, Raja N. , STADLER, Robert W. , ZHANG, Xusheng , KLECKNER, Karin J. , KRAUSE, Paul, G. , KRAUSE, Paul, G.
IPC分类号： A61B5/046 , A61B5/0464 , A61B5/0472 , A61N1/362 , A61N1/39
CPC分类号： A61B5/0464 , A61B5/7239 , A61N1/3621 , A61N1/3704 , A61N1/3925
摘要： A method and apparatus for determining oversensing in a medical device that includes sensing cardiac signals, determining an oversensing characteristic associated with cardiac signals sensed during a predetermined sensing window, identifying oversensing in response to the oversensing characteristic, determining, in response to oversensing being identified, an adjusting characteristic associated with cardiac signals sensed during the predetermined sensing window, and updating a sensing parameter in response to the determined adjusting characteristic.
摘要翻译：一种用于确定医疗装置中的过度感测的方法和装置，包括感测心脏信号，确定与在预定感测窗口期间感测到的心脏信号相关联的过度感应特征，响应于过敏特性识别过敏，响应于被识别的过冷而确定，与在预定感测窗口期间感测到的心脏信号相关联的调整特性，以及响应于确定的调整特性来更新感测参数。

2. 发明申请

WO2008137536A1 METHOD AND APPARATUS FOR DETECTING ARRHYTHMIAS IN A MEDICAL DEVICE 审中-公开
标题翻译：用于检测医疗器械中的ARRHYTHMIAS的方法和装置
公开(公告)号：WO2008137536A1
公开(公告)日：2008-11-13
申请号：PCT/US2008/062201
申请日：2008-05-01
申请人： MEDTRONIC, INC. , GHANEM, Raja N. , STADLER, Robert W. , ZHANG, Xusheng , KLECKNER, Karin J. , KRAUSE, Paul, G.
发明人： GHANEM, Raja N. , STADLER, Robert W. , ZHANG, Xusheng , KLECKNER, Karin J. , KRAUSE, Paul, G.
IPC分类号： A61B5/046 , A61B5/0464 , A61B5/0472 , A61N1/362 , A61N1/39
CPC分类号： A61N1/3704 , A61B5/046 , A61B5/0464 , A61B5/7239 , A61N1/3621 , A61N1/3925
摘要： A method and apparatus for adjusting a sensing parameter in a medical device that includes a sensing electrode sensing cardiac signals, a processor to determine an adjusting characteristic associated with the cardiac signals sensed over a predetermined sensing window, and a control unit to update the sensing parameter in response to the determined adjusting characteristic.
摘要翻译：一种用于调整包括感测心脏信号的感测电极的医疗装置中的感测参数的方法和装置，用于确定与在预定感测窗口上感测到的心脏信号相关联的调整特性的处理器以及用于更新感测参数的控制单元响应于确定的调整特性。

3. 发明申请

WO2010033405A1 METHOD AND APPARATUS FOR DETECTING RESPIRATORY EFFORT IN A MEDICAL DEVICE 审中-公开
标题翻译：用于检测医疗装置中呼吸道作用的方法和装置
公开(公告)号：WO2010033405A1
公开(公告)日：2010-03-25
申请号：PCT/US2009/056305
申请日：2009-09-09
申请人： MEDTRONIC, INC. , CHO, Yong K. , BENNETT, Tommy D. , ERICKSON, Mark K. , SHRIVASTAV, Maneesh , GREENHUT, Saul E. , KLECKNER, Karin J. , SPERLING, Charles P. , COREY, Robert A.
发明人： CHO, Yong K. , BENNETT, Tommy D. , ERICKSON, Mark K. , SHRIVASTAV, Maneesh , GREENHUT, Saul E. , KLECKNER, Karin J. , SPERLING, Charles P. , COREY, Robert A.
IPC分类号： A61B5/08 , A61B5/0205 , A61B5/03 , A61N1/365 , A61N1/37 , A61N1/372 , H03H21/00
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/0816 , A61B5/4818 , A61N1/36514 , A61N1/3702 , A61N1/37258
摘要： A medical device for determining a respiratory effort having a pressure sensor to sense pressure signals, a housing having system components positioned therein, and a microprocessor positioned within the housing, wherein the microprocessor detects an inspiration and an expiration in response to the pressure signals, detects a breath in response to the detected inspiration and the detected expiration, and determines the respiratory effort in response to the detected breath.
摘要翻译：一种用于确定具有用于感测压力信号的压力传感器的呼吸力的医疗装置，具有定位在其中的系统部件的壳体和位于壳体内的微处理器，其中微处理器响应于压力信号检测吸气和呼气，检测响应于检测到的吸气和检测到的呼气而呼吸，并且响应于检测到的呼吸来确定呼吸努力。

4. 发明申请

WO2010111207A1 COMBINED HEMODYNAMIC AND EGM-BASED ARRHYTHMIA DETECTION 审中-公开
标题翻译：联合HEMODYNAMIC和基于EGM的ARRHYTHMIA检测
公开(公告)号：WO2010111207A1
公开(公告)日：2010-09-30
申请号：PCT/US2010/028213
申请日：2010-03-23
申请人： MEDTRONIC, INC. , WHITMAN, Teresa A. , KUMAR, Arun , KLECKNER, Karin J. , GILLBERG, Jeffrey M. , JACKSON, Troy E. , SHRIVASTAV, Maneesh , BROWN, Mark L.
发明人： WHITMAN, Teresa A. , KUMAR, Arun , KLECKNER, Karin J. , GILLBERG, Jeffrey M. , JACKSON, Troy E. , SHRIVASTAV, Maneesh , BROWN, Mark L.
IPC分类号： A61N1/39 , A61B5/0205 , A61B5/046 , A61B5/0464 , A61B5/0215 , A61N1/365
CPC分类号： A61N1/3621 , A61B5/0215 , A61B5/0464 , A61N1/36564 , A61N1/36571 , A61N1/36578
摘要： A medical device for detecting arrhythmias that includes sensing cardiac electrical signals and cardiac hemodynamic signals, determining a long-term baseline hemodynamic measurement in response to a plurality of the sensed cardiac hemodynamic signals, detecting a period of increased metabolic demand in response to the sensed cardiac electrical signals, determining a sinus tachycardia baseline hemodynamic measurement in response to sensing of cardiac hemodynamic signals during the detected period of increased metabolic demand, and detecting the arrhythmia and delivering therapy in response to one of only the sensed cardiac electrical signals and the sensed cardiac electrical signals in combination with one or both of the determined long-term baseline hemodynamic measurement and the sinus tachycardia baseline hemodynamic measurement.
摘要翻译：一种用于检测心律失常的医疗装置，其包括感测心脏电信号和心脏血液动力学信号，响应于多个所感测到的心脏血流动力信号确定长期基线血液动力学测量，响应于感测的心脏检测增加的代谢需求的时期电信号，响应于在增加的代谢需求的检测期间响应于心脏血液动力学信号的感测而确定窦性心动过速基线血液动力学测量，以及响应于仅感测的心电信号和感测到的心脏电信之一检测心律失常并递送治疗信号与确定的长期基线血液动力学测量和窦性心动过速基线血液动力学测量中的一个或两个相结合。

5. 发明申请

WO2008097959A1 FUSION PACING ENHANCEMENTS 审中-公开
标题翻译：融合增强
公开(公告)号：WO2008097959A1
公开(公告)日：2008-08-14
申请号：PCT/US2008/053037
申请日：2008-02-05
申请人： MEDTRONIC, INC. , BURNES, John E. , KLECKNER, Karin J. , MULLEN, Thomas J.
发明人： BURNES, John E. , KLECKNER, Karin J. , MULLEN, Thomas J.
IPC分类号： A61N1/368
CPC分类号： A61N1/3627 , A61N1/3682 , A61N1/3684
摘要： The disclosure provides methods and apparatus of left ventricular pacing including automated adjustment of a atrio-ventricular (AV) pacing delay interval and intrinsic AV nodal conduction testing. It includes - upon expiration or reset of a programmable AV Evaluation Interval (AVEI) - performing the following: temporarily increasing a paced AV interval and a sensed AV interval and testing for adequate AV conduction and measuring an intrinsic atrio-ventricular (PR) interval for a right ventricular (RV) chamber. Thus, in the event that the AV conduction test reveals a physiologically acceptable intrinsic PR interval then storing the physiologically acceptable PR interval in a memory structure (e.g., a median P-R from one or more cardiac cycles). In the event that the AV conduction test reveals an AV conduction block condition or if unacceptably long PR intervals are revealed then a pacing mode-switch to a bi-ventricular (Bi-V) pacing mode occurs and the magnitude of the AVEI is increased.
摘要翻译：本公开提供了左心室起搏的方法和装置，包括自动调节心房（AV）起搏延迟间隔和内部AV节点传导测试。它包括 - 在可编程AV评估间隔（AVEI）到期或复位时 - 执行以下操作：临时增加节奏的AV间隔和感测到的AV间隔，并测试足够的AV传导并测量内在房室（PR）间隔右心室（RV）室。因此，在AV传导测试揭示生理上可接受的内在PR间隔的情况下，然后将生理上可接受的PR间期存储在存储器结构中（例如，来自一个或多个心动周期的中值P-R）。在AV传导测试显示AV传导阻滞状态或者如果不能接受的长PR间隔被揭示的情况下，则起搏模式切换到双心室（Bi-V）起搏模式并且AVEI的幅度增加。

6. 发明申请

WO2010033400A1 FILTERING OF A PHYSIOLOGIC SIGNAL IN A MEDICAL DEVICE 审中-公开
标题翻译：医疗设备中生理信号的过滤
公开(公告)号：WO2010033400A1
公开(公告)日：2010-03-25
申请号：PCT/US2009/056184
申请日：2009-09-08
申请人： MEDTRONIC, INC. , CHO, Yong K. , BENNETT, Tommy D. , ERICKSON, Mark K. , SHRIVASTAV, Maneesh , KLECKNER, Karin J. , SPERLING, Charles P. , COREY, Robert A. , GREENHUT, Saul E.
发明人： CHO, Yong K. , BENNETT, Tommy D. , ERICKSON, Mark K. , SHRIVASTAV, Maneesh , KLECKNER, Karin J. , SPERLING, Charles P. , COREY, Robert A. , GREENHUT, Saul E.
IPC分类号： A61B5/08 , A61B5/0205 , A61B5/03 , H03H21/00 , A61N1/365 , A61N1/37 , A61N1/372
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/0816 , A61B5/4818 , A61N1/36514 , A61N1/3702 , A61N1/37258
摘要： A system and method for filtering a pressure signal in a medical device in which a sensor terminal senses the pressure signal, an electrode terminal receives cardiac electrical signals, a signal filtering system filters the sensed pressure signal in response to a determined heart rate to generate a heart-rate dependent frequency response, and a microprocessor derives a respiration signal in response to the heart rate dependent frequency response, and determines metrics of hemodynamic function in response to the derived respiration signal.
摘要翻译：一种用于过滤医疗装置中的压力信号的系统和方法，其中传感器端子感测压力信号，电极端子接收心脏电信号，信号滤波系统响应于确定的心率来过滤感测到的压力信号，以产生心率依赖频率响应，并且微处理器响应于心率依赖的频率响应导出呼吸信号，并且响应于所得到的呼吸信号确定血液动力学函数的度量。

7. 发明公开

EP2152152A1 METHOD AND APPARATUS FOR DETECTING ARRHYTHMIAS IN A MEDICAL DEVICE 审中-公开
标题翻译：方法和装置性心律失常的医疗设备检测
公开(公告)号：EP2152152A1
公开(公告)日：2010-02-17
申请号：EP08747333.6
申请日：2008-05-01
申请人： MEDTRONIC, INC.
发明人： GHANEM, Raja N. , STADLER, Robert W. , ZHANG, Xusheng , KLECKNER, Karin J. , KRAUSE, Paul, G.
IPC分类号： A61B5/046 , A61B5/0464 , A61B5/0472 , A61N1/362 , A61N1/39
CPC分类号： A61B5/0464 , A61B5/7239 , A61N1/3621 , A61N1/3704 , A61N1/3925
摘要： A method and apparatus for determining oversensing in a medical device that includes sensing cardiac signals, determining an oversensing characteristic associated with cardiac signals sensed during a predetermined sensing window, identifying oversensing in response to the oversensing characteristic, determining, in response to oversensing being identified, an adjusting characteristic associated with cardiac signals sensed during the predetermined sensing window, and updating a sensing parameter in response to the determined adjusting characteristic.

8. 发明授权

EP2358273B1 APPARATUS FOR DETECTING RESPIRATORY EFFORT IN A MEDICAL DEVICE 有权
标题翻译：装置，用于检测呼吸努力医疗设备中
公开(公告)号：EP2358273B1
公开(公告)日：2016-07-13
申请号：EP09792348.6
申请日：2009-09-09
申请人： Medtronic, Inc.
发明人： CHO, Yong K. , BENNETT, Tommy D. , ERICKSON, Mark K. , SHRIVASTAV, Maneesh , GREENHUT, Saul E. , KLECKNER, Karin J. , SPERLING, Charles P. , COREY, Robert A.
IPC分类号： A61B5/0205 , A61B5/00 , A61B5/0215 , A61B5/08 , A61N1/365 , A61N1/37 , A61N1/372
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/0816 , A61B5/4818 , A61N1/36514 , A61N1/3702 , A61N1/37258

9. 发明授权

EP2117646B1 FUSION PACING ENHANCEMENTS 有权
标题翻译：改进融合起搏
公开(公告)号：EP2117646B1
公开(公告)日：2013-09-04
申请号：EP08729034.2
申请日：2008-02-05
申请人： Medtronic, Inc.
发明人： BURNES, John E. , KLECKNER, Karin J. , MULLEN, Thomas J.
IPC分类号： A61N1/368
CPC分类号： A61N1/3627 , A61N1/3682 , A61N1/3684

10. 发明公开

EP2358273A1 METHOD AND APPARATUS FOR DETECTING RESPIRATORY EFFORT IN A MEDICAL DEVICE 有权
标题翻译：装置，用于检测呼吸努力医疗设备中
公开(公告)号：EP2358273A1
公开(公告)日：2011-08-24
申请号：EP09792348.6
申请日：2009-09-09
申请人： Medtronic, Inc.
发明人： CHO, Yong K. , BENNETT, Tommy D. , ERICKSON, Mark K. , SHRIVASTAV, Maneesh , GREENHUT, Saul E. , KLECKNER, Karin J. , SPERLING, Charles P. , COREY, Robert A.
IPC分类号： A61B5/08 , A61B5/0205 , A61B5/03 , A61N1/365 , A61N1/37 , A61N1/372 , H03H21/00
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/0816 , A61B5/4818 , A61N1/36514 , A61N1/3702 , A61N1/37258
摘要： A medical device for determining a respiratory effort having a pressure sensor to sense pressure signals, a housing having system components positioned therein, and a microprocessor positioned within the housing, wherein the microprocessor detects an inspiration and an expiration in response to the pressure signals, detects a breath in response to the detected inspiration and the detected expiration, and determines the respiratory effort in response to the detected breath.

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