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    • 2. 发明申请
    • IMPLANTABLE MEDICAL CATHETER CONNECTOR FOR MEDICAL TUBING WITH ANCHORING FEATURES
    • 具有锚固特征的医用导管接头医用导管连接器
    • WO2003090840A1
    • 2003-11-06
    • PCT/US2003/012245
    • 2003-04-17
    • MEDTRONIC, INC.
    • OLSEN, James, M.HEGLAND, Michael
    • A61M39/10
    • A61M39/12A61M2039/1027
    • A connector (20) includes at least a first protrusion (38) and a second protrusion (40) projecting from the connector(20), and a first and second tubular strain reliefs (42, 52). The first end (24) of the connector (20) is inserted into a proximal connector-receiving portion to form a first interlock fit, and the second end (32) of the connector (20) is inserted into the distal connector-receiving portion to form a second interlock fit, resulting in a fluid tight connection between the proximal connector-receiving portion and the distal connector-receiving portion, with at least a middle portion (28) of the connector (20) exposed. The middle portion (28) of the connector (20) can include a suture receiving section that can be sutured to tissue of patient.
    • 连接器(20)至少包括从连接器(20)突出的第一突起(38)和第二突起(40),以及第一和第二管状应变释放元件(42,52)。 连接器(20)的第一端(24)被插入到近端连接器接收部分中以形成第一互锁配合,并且连接器(20)的第二端(32)插入到远端连接器接收部分 以形成第二互锁配合,导致近侧连接器接收部分和远端连接器接收部分之间的流体密封连接,其中连接器(20)的至少中间部分(28)暴露。 连接器(20)的中间部分(28)可以包括可缝合到患者组织的缝线接收部分。
    • 10. 发明申请
    • THREE-DIMENSIONAL IN-VITRO SPINAL MODELS AND METHODS OF ANALYZING SUBSTANCE DISTRIBUTION THEREIN
    • 三维体内脊髓模型和分析其中物质分布的方法
    • WO2005036502A2
    • 2005-04-21
    • PCT/US2004/032642
    • 2004-10-01
    • MEDTRONIC, INC.HERUTH, Kenneth, T.LENT, Mark, S.HEGLAND, Michael
    • HERUTH, Kenneth, T.LENT, Mark, S.HEGLAND, Michael
    • G09B23/28
    • G09B23/34B33Y50/00B33Y80/00G09B23/30
    • An in-vitro model apparatus of a human spine and methods for detecting and analyzing substance distribution patterns therein. In one embodiment, the model apparatus includes a column body defining a passageway that substantially mimics the size, shape, and structure of an adult human spinal canal. Also included is a cord structure that may be located and anchored within the passageway. The cord structure substantially mimics the size, shape, and structure of an adult human spinal cord. For example, the cord structure may include connecting elements that resemble nerve roots, dentate ligaments, and the septum posticurn of a human spine. The passageway of the model apparatus may be filled with a first fluid that simulates cerebro-spinal fluid (CSF), and a second fluid containing a drug (or simulated drug) may be introduced into the passageway, after which the drug's distribution within the passageway may be analyzed.
    • 人体脊柱的体外模型装置和用于检测和分析其中的物质分布模式的方法 在一个实施例中,模型设备包括限定通道的柱体,该通道基本上模仿成人椎管的尺寸,形状和结构。 还包括可以定位并锚定在通道内的绳索结构。 绳结构基本上模仿成人脊髓的尺寸,形状和结构。 例如,绳结构可以包括类似于神经根,齿状韧带和人体脊柱的间隔的连接元件。 模型设备的通道可以填充模拟脑脊髓液(CSF)的第一流体,并且可以将含有药物(或模拟药物)的第二流体引入通道中,之后药物在通道内分布 可能会被分析。