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1. 发明申请

WO2018026387A1 ANTI-ROTATION CARTRIDGE PIN 审中-公开
标题翻译：防旋转底盘密码
公开(公告)号：WO2018026387A1
公开(公告)日：2018-02-08
申请号：PCT/US2016/068065
申请日：2016-12-21
申请人： MEDIMOP MEDICAL PROJECTS LTD. , WEST PHARMACEUTICAL SERVICES, INC.
发明人： BARCHEN, Lior , BAR-EL, Yossi
IPC分类号： A61M5/24 , A61M5/28 , A61M5/145 , A61J1/06
摘要： A system is disclosed for inserting a pharmaceutical cartridge into a delivery device. Optionally the cartridge is inserted in an arbitrary orientation. Optionally, the system reorients the cartridge to a locked orientation. For example, a driver applies a torque to the cartridge to cause the reorienting. For example, said torque rotates the cartridge around an axis thereof until the cartridge reaches the locked orientation. Optionally, when the cartridge reaches the locked orientation an interference element on the cartridge interlocks with a complementary interference element on the delivery device to lock the cartridge in the locked orientation. Optionally when the cartridge is locked in the second orientation, the torque causes discharge the pharmaceutical.
摘要翻译：公开了一种用于将药筒插入递送装置的系统。可选地，盒以任意方向插入。或者，系统将墨盒重新定向至锁定方向。例如，驾驶员将扭矩施加到墨盒以引起重新定向。例如，所述扭矩使药筒围绕其轴线旋转，直到药筒达到锁定定向。可选地，当盒到达锁定方位时，盒上的干涉元件与输送装置上的互补干涉元件互锁以将盒锁定在锁定方位。可选地，当药筒以第二取向锁定时，扭矩导致药物排出。

2. 发明申请

WO2018026385A1 PARTIAL DOOR CLOSURE PREVENTION SPRING 审中-公开
标题翻译：部分车门关闭防止弹簧
公开(公告)号：WO2018026385A1
公开(公告)日：2018-02-08
申请号：PCT/US2016/068049
申请日：2016-12-21
申请人： MEDIMOP MEDICAL PROJECTS LTD. , WEST PHARMACEUTICAL SERVICES, INC.
发明人： BARCHEN, Lior , BAR-EL, Yossi
IPC分类号： A61M5/14
摘要： A drug delivery device, including: housing, wherein said housing defines an opening and a chamber for a drug cartridge; a movable door connected to the housing, having a range of movement between a fully open position and a closed position, wherein the door blocks access to said opening when the door is in said closed position; a biasing element connected to the housing or the door, wherein the biasing element is positioned to interfere with the movement of the door by applying an opening force to open the door when the range of movement of the door is near the closed position, thus defining an exclusion zone; and a locking mechanism between the door and the housing, the locking mechanism applies a locking force on the door greater and in an opposite direction to the force applied by the biasing element.
摘要翻译：药物输送装置，包括：壳体，其中所述壳体限定用于药筒的开口和腔室; 连接到所述壳体的可动门，所述可动门具有在完全打开位置和关闭位置之间的运动范围，其中，当所述门处于所述关闭位置时，所述门阻挡所述开口进入所述开口; 偏置元件，所述偏置元件连接到所述壳体或所述门，其中所述偏置元件定位成当所述门的移动范围接近所述关闭位置时通过施加打开力来打开所述门来干扰所述门的移动，从而限定禁区; 以及在门与壳体之间的锁定机构，锁定机构在门上施加锁定力，该锁定力更大并且与由偏压元件施加的力相反的方向上施加锁定力。

3. 发明申请

WO2016196934A1 CARTRIDGE INSERTION FOR DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置的药盒插入物
公开(公告)号：WO2016196934A1
公开(公告)日：2016-12-08
申请号：PCT/US2016/035720
申请日：2016-06-03
申请人： MEDIMOP MEDICAL PROJECTS LTD. , WEST PHARMACEUTICAL SERVICES, INC.
发明人： BAR-EL, Yossi , YIGAL, Gil , FILMAN, Reuven, Y.
IPC分类号： A61M5/24 , A61M5/20 , A61M5/142
CPC分类号： A61M5/2422 , A61M5/14244 , A61M5/2033 , A61M5/2053 , A61M5/24 , A61M5/2466 , A61M2005/2414 , A61M2005/2437 , A61M2005/2477 , A61M2005/2496
摘要： A method and assembly are disclosed for interfacing between a drug cartridge and a drug delivery device. Optionally, the drug delivery device includes a compartment that retains the cartridge during drug delivery and/or a stopper pushing assembly mounted to the device behind (proximal to) the compartment. In some embodiments, the cartridge may be inserted laterally into the compartment in front of the pushing assembly. For example, the delivery device may include a moving cartridge bay. The cartridge is optionally inserted into the bay and/or the bay and cartridge optionally move into the cartridge compartment. Alternatively or additionally, the cartridge compartment may have a proximal opening into which the cartridge is inserted and/or the pushing assembly may be moved into position after insertion of the cartridge. In some embodiments the cartridge may have a distal seal that is broken by a longitudinal movement.
摘要翻译：公开了用于药物盒和药物递送装置之间的接口的方法和组件。任选地，药物递送装置包括在药物递送期间保持药筒和/或在隔室后面（靠近）安装到装置上的止动器推动组件的隔室。在一些实施例中，盒可以横向插入到推动组件前面的隔室中。例如，传送设备可以包括移动盒托架。墨盒可选地插入托架和/或托架和墨盒可选地移动到墨盒隔间中。替代地或另外地，盒室可以具有近端开口，盒被插入到其中，和/或推动组件可以在插入盒之后移动到位。在一些实施例中，盒可以具有由纵向运动破坏的远侧密封件。

4. 发明申请

WO2018026386A1 AUTOMATIC INJECTOR HAVING DOOR BLOCK UNTIL PROPER CARTRIDGE INSERTION 审中-公开
标题翻译：自动注射器直到合适的插入器插入
公开(公告)号：WO2018026386A1
公开(公告)日：2018-02-08
申请号：PCT/US2016/068058
申请日：2016-12-21
申请人： MEDIMOP MEDICAL PROJECTS LTD. , WEST PHARMACEUTICAL SERVICES, INC.
发明人： BARCHEN, Lior , BAR-EL, Yossi
IPC分类号： A61M5/145 , A61M5/142
摘要： An automatic injector device for delivering a pharmaceutical substance from a cartridge having a protruding edge, positioned in a housing cartridge bay having an opening sized to allow passage of the cartridge; a door to the cartridge bay opening, the door connected to the housing and having an unlatched position and a latched position, the door defining a trajectory between the unlatched position and the latched position; an interference element having a deflected and an inflected orientation, the deflected orientation mechanically interferes with the trajectory of the door; and a contact interface positioned along the cartridge bay and extending up to the protruding edge, the contact interface mechanically couples the deflected and inflected orientation with a sensed contact of the protruding edge, such that when the protruding edge is positioned at the contact interface, the contact interface shifts the interference element into the inflected orientation.
摘要翻译：自动注射器装置，用于从具有突出边缘的药筒传送药物物质，所述药筒位于具有开口的外壳药筒架中，所述开口的尺寸允许所述药筒通过; 所述盒门开口的门，所述门连接到所述壳体并且具有未锁定位置和锁定位置，所述门限定在所述未锁定位置和所述锁定位置之间的轨迹; 具有偏转和屈曲取向的干涉元件，偏转取向机械干涉门的轨迹; 以及接触界面，所述接触界面沿着所述药筒舱位并延伸到所述突出边缘，所述接触界面将所述偏转和屈曲取向与所述突出边缘的感测触点机械地联接，使得当所述突出边缘定位在所述接触界面时，所述接触界面将干涉元件移动到屈曲方向。

5. 发明申请

WO2017210448A1 THREE POSITION NEEDLE RETRACTION 审中-公开
标题翻译：三位针回缩
公开(公告)号：WO2017210448A1
公开(公告)日：2017-12-07
申请号：PCT/US2017/035486
申请日：2017-06-01
申请人： MEDIMOP MEDICAL PROJECTS LTD. , WEST PHARMACEUTICAL SERVICES, INC.
发明人： YUDELEVICH, Michael , BAR-EL, Yossi , YIGAL, Gil , FILMAN, Reuven, Y.
IPC分类号： A61M5/32
摘要： In some embodiments a system and method are described for safeguarding a hazard, the hazard, for example a needle point, may be moved between a protected retracted position, an active extended position and/or an intermediate position. Optionally in the retracted position, the hazard may be protected inside a housing. Optionally in the extended position, the hazard may be exposed. Optionally, in the intermediate position the hazard may be partially protected and/or concealed, for example by a shield and/or in an indentation. In some embodiments, compromising a shield causes the hazard to be retracted to the retracted position.
摘要翻译：在一些实施例中，描述了用于保护危险的系统和方法，危险（例如针尖）可以在受保护的缩回位置，主动伸出位置和/或中间位置。可选地，在缩回位置中，危险可以在壳体内受到保护。可选地，在伸展位置，危险可能会暴露。可选地，在中间位置中，危险可以例如通过护罩和/或凹陷被部分地保护和/或隐藏。在一些实施例中，危害护罩会导致危险缩回到缩回位置。

6. 发明公开

EP4378500A3 LINEAR ROTATION STABILIZER FOR A TELESCOPING SYRINGE STOPPER DRIVERDRIVING ASSEMBLY 审中-公开
公开(公告)号：EP4378500A3
公开(公告)日：2024-08-28
申请号：EP24171686.9
申请日：2016-05-27
申请人： Medimop Medical Projects Ltd.
发明人： FILMAN, Rueven Y. , YIGAL, Gil , BAR-EL, Yossi
IPC分类号： A61M5/315 , A61M5/20 , A61M5/145
CPC分类号： A61M5/1452 , A61M5/20 , A61M5/31511 , A61M5/31576 , A61M2005/3158820130101 , A61M2205/820620130101 , A61M5/14566 , A61M2005/3151820130101
摘要： A cartridge interface assembly drives a stopper in a drug reservoir or a drug delivery device. An anti-rotational guide optionally moves along an axis of a cavity of the reservoir. The anti-rotational guide is optionally slidably anti-rotationally coupled to a housing of the drug delivery device. A telescoping plunger driver may include a proximal shaft and distal shaft that telescope by relative rotation. The distal shaft is optionally slidably anti-rotationally coupled to the anti-rotational guide. The shafts are optionally oriented along said axis. In some embodiments, rotating the proximal shaft with respect to the anti-rotational guide moves the guide along said axis with respect to the housing and moves the distal shaft along the axis with respect to the anti-rotational guide.

7. 发明公开

EP4378500A2 LINEAR ROTATION STABILIZER FOR A TELESCOPING SYRINGE STOPPER DRIVERDRIVING ASSEMBLY 审中-公开
公开(公告)号：EP4378500A2
公开(公告)日：2024-06-05
申请号：EP24171686.9
申请日：2016-05-27
申请人： Medimop Medical Projects Ltd.
发明人： FILMAN, Rueven Y. , YIGAL, Gil , BAR-EL, Yossi
IPC分类号： A61M5/145
CPC分类号： A61M5/1452 , A61M5/20 , A61M5/31511 , A61M5/31576 , A61M2005/3158820130101 , A61M2205/820620130101
摘要： A cartridge interface assembly drives a stopper in a drug reservoir or a drug delivery device. An anti-rotational guide optionally moves along an axis of a cavity of the reservoir. The anti-rotational guide is optionally slidably anti-rotationally coupled to a housing of the drug delivery device. A telescoping plunger driver may include a proximal shaft and distal shaft that telescope by relative rotation. The distal shaft is optionally slidably anti-rotationally coupled to the anti-rotational guide. The shafts are optionally oriented along said axis. In some embodiments, rotating the proximal shaft with respect to the anti-rotational guide moves the guide along said axis with respect to the housing and moves the distal shaft along the axis with respect to the anti-rotational guide.

8. 发明授权

EP3064235B1 COMPLIANT COUPLING ASSEMBLY FOR CARTRIDGE COUPLING OF A DRUG DELIVERY DEVICE 有权转让
公开(公告)号：EP3064235B1
公开(公告)日：2019-04-10
申请号：EP16157430.6
申请日：2016-02-25
申请人： Medimop Medical Projects Ltd.
发明人： BAR-EL, Yossi , VENISLAVSKI, Evgeni , SOLOMON, Tomer , FILMAN, Rueven Y.
IPC分类号： A61M5/162 , A61M39/14

9. 发明公开

EP3490637A1 AUTOMATIC INJECTOR HAVING DOOR BLOCK UNTIL PROPER CARTRIDGE INSERTION 有权转让
公开(公告)号：EP3490637A1
公开(公告)日：2019-06-05
申请号：EP16825662.6
申请日：2016-12-21
申请人： Medimop Medical Projects Ltd
发明人： BARCHEN, Lior , BAR-EL, Yossi
IPC分类号： A61M5/145 , A61M5/142

10. 发明公开

EP3067083A1 FLEXIBLY MOUNTED CARTRIDGE ALIGNMENT COLLAR FOR DRUG DELIVERY DEVICE 有权
标题翻译： FLEXIBEL MONTIERTER PATRONENAUSRICHTUNGSKRAGENFÜREINE ARZNEIMITTELABGABEVORRICHTUNG
公开(公告)号：EP3067083A1
公开(公告)日：2016-09-14
申请号：EP16157422.3
申请日：2016-02-25
申请人： Medimop Medical Projects Ltd.
发明人： BAR-EL, Yossi , SOLOMON, Tomer , FILMAN, Rueven Y.
IPC分类号： A61M5/24 , A61M5/34 , A61M5/145
CPC分类号： A61J1/1406 , A61M5/1413 , A61M5/1456 , A61M5/1782 , A61M5/24 , A61M5/34 , A61M2209/045
摘要： An alignment assembly for a cartridge interface of a drug delivery device is disclosed. The assembly optionally includes a coupling for opening fluid communication between the cartridge and the delivery device. For example, the coupling optionally includes a cannula insertable through a septum of the cartridge. The assembly may include a guide for positioning the cartridge and/or an access channel thereof within a first precision of a loaded position. The assembly optionally includes a cartridge engagement fitting (for example a gripping expander sleeve collar) attached to the coupling. Optionally when the cartridge is engaged to the fitting, the coupling is retained in connection with the access channel to within a second precision. The second precision is optionally higher than the first precision. In some embodiments one or more compliant supports movably retain the fitting oriented to engage the cartridge when the access channel is in the loaded position.
摘要翻译：公开了用于药物输送装置的药筒接口的对准组件。组件可选地包括用于打开盒和输送装置之间的流体连通的联接器。例如，联接器可选地包括可插入通过盒的隔膜的套管。组件可以包括用于将盒和/或其访问通道定位在加载位置的第一精度内的引导件。组件可选地包括附接到联接器的盒接合配件（例如，夹紧膨胀器套筒套环）。可选地，当墨盒与配件接合时，耦合件与接入通道相连以保持在第二精度内。第二精度可选地高于第一精度。在一些实施例中，当接入通道处于加载位置时，一个或多个柔性支撑件可移动地保持定位成接合盒的配件。

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