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    • 3. 发明申请
    • LIQUID DRUG DELIVERY SYSTEM
    • 液体药物输送系统
    • WO2007015233A1
    • 2007-02-08
    • PCT/IL2006/000881
    • 2006-07-31
    • MEDIMOP MEDICAL PROJECTS LTDZINGER, FreddyDENENBURG, Igor
    • ZINGER, FreddyDENENBURG, Igor
    • A61J1/00
    • A61J1/2096A61J1/201A61J1/2031A61J1/2051A61J1/2075
    • Liquid drug delivery system including an actuating connector (11) with a two-part housing reciprocal between an expanded operative state and a compressed operative state. The actuating connector (11) is coupled on an actuated connector (13) with a Normally Closed (NC) valve (16) having an exteriorly accessible end surface with a Normally Closed (NC) port"Tδ"2) which is opened on manipulation of the actuating connector (11) from its initial expanded operative state to its compressed operative state to enable an initially occluded flow path. The NC valve's exteriorly accessible end surface is dry subsequent to reverse manipulation of the actuating connector (11) and de-coupling "The actuating connector (11) from the actuated connector (13) . A range of actuated connectors (13) are available for handling hazardous liquid drugs supplied in pre-filled syringes or requiring reconstitution, and different modes of administration to a subject. Intended modes of administration include inter alia injection, drip feed, intravenous injection, and the like.
    • 液体药物递送系统包括具有在扩展的操作状态和压缩操作状态之间往复运动的两部分壳体的致动连接器(11)。 致动连接器(11)通过具有外部可接近端面的常闭(NC)阀(16)联接在致动连接器(13)上,该端盖具有常开(NC)端口“Td”2) 致动连接器(11)从其初始扩展的操作状态到其压缩的操作状态以使得能够初始闭塞的流动路径。 在执行连接器(11)的反向操作之后,数控阀的外部可接近的端面是干燥的,并且将致动连接器(11)从致动连接器(13)解耦。一系列致动连接器(13)可用于 处理预填充注射器中提供的危险液体药物或需要重建,以及对受试者施用不同的给药方式。给药方式包括注射,滴注,静脉内注射等。
    • 4. 发明申请
    • FLUID CONTROL DEVICE WITH MANUALLY DEPRESSED ACTUATOR
    • 具有手动执行器的流体控制装置
    • WO2008126090A1
    • 2008-10-23
    • PCT/IL2008/000517
    • 2008-04-16
    • MEDIMOP MEDICAL PROJECTS LTDZINGER, FreddyDENENBURG, Igor
    • ZINGER, FreddyDENENBURG, Igor
    • A61J1/20
    • A61J1/2096A61J1/201A61J1/2037A61J1/2058A61M39/223A61M2039/229
    • Fluid control device (70) including a housing (31) with a syringe port (33) for receiving a syringe, a vial adapter port (36) with a vial adapter (86) for snap fit receiving a vial, and a drug administration port (34) for administering a liquid drug. The vial adapter is intended to be rotationally detached after a mixing procedure for discarding together with a spent vial. The fluid control device additionally includes a manually depressed actuator (74) for sealing pathways which may lead to leakage of liquid drug subsequent to vial adapter detachment, thereby facilitating their use for handling and administration of hazardous liquid drugs. The manually depressed actuator preferably precludes vial adapter detachment prior to actuation, thereby ensuring failsafe operation.
    • 流体控制装置(70)包括具有用于接收注射器的注射器端口(33)的壳体(31),具有适于接合小瓶的小瓶适配器(86)的小瓶适配器端口(36)和药物管理端口 (34),用于施用液体药物。 小瓶适配器旨在在混合程序之后旋转分离,以与废样品瓶一起丢弃。 流体控制装置还包括用于密封通路的手动按压致动器(74),其可能导致在药液瓶适配器拆卸之后泄漏液体药物,从而便于其用于处理和施用危险液体药物。 手动按压的致动器优选地在致动之前防止小瓶适配器拆卸,从而确保故障安全操作。
    • 5. 发明申请
    • NEEDLELESS ADDITIVE CONTROL VALVE
    • 无需辅助控制阀
    • WO2007052252A1
    • 2007-05-10
    • PCT/IL2006/001228
    • 2006-10-26
    • MEDIMOP MEDICAL PROJECTS LTDZINGER, FreddyDENENBURG, Igor
    • ZINGER, FreddyDENENBURG, Igor
    • A61J1/00A61M5/14A61M39/00
    • A61J1/20A61J1/10A61J1/1406A61J1/1412A61J1/1468A61J1/1487A61M5/162A61M39/045A61M39/26
    • A needleless additive control valve for use with a fluid container containing an infusion liquid and having an intravenous (IV) port for administrating the infusion liquid, and an additive transfer device containing a liquid additive and having a male connector for administrating the liquid additive. The needleless additive control valve includes a trifurcated connector body having an IV spike for sealing insertion into the IV port, a substitute IV port for sealingly receiving an IV spike, and a normally closed (NC) needleless additive port with a female connector for sealingly receiving the additive transfer device's male connector. The IV spike, the substitute IV port and the NC needleless additive port are in 3 way direct and continuous fluid communication whereby the additive transfer device's liquid additive is able to be either mixed with the infusion liquid or directly administered to a patient.
    • 一种无针添加剂控制阀,其与含有输注液体的流体容器一起使用,并具有用于施用输注液的静脉内(IV)端口,以及含有液体添加剂的添加剂转移装置,并具有用于施用液体添加剂的阳连接器。 无针添加剂控制阀包括具有用于密封插入IV端口的IV尖钉的三叉连接器主体,用于密封地接收IV尖钉的替代IV端口和具有阴连接器的常闭(NC)无针加法端口,用于密封地接收 添加剂转移装置的公连接器。 IV尖峰,替代IV端口和NC无针加药口是三通直接和连续的流体连通,其中添加剂转移装置的液体添加剂能够与输注液混合或直接施用于患者。
    • 9. 发明申请
    • LIQUID DRUG DELIVERY DEVICES FOR USE WITH SYRINGES WITH WIDENED DISTAL TIPS
    • 液体药物递送装置,使用带有更宽的远距离提示的口令
    • WO2009040804A2
    • 2009-04-02
    • PCT/IL2008/001278
    • 2008-09-24
    • MEDIMOP MEDICAL PROJECTS LTDZINGER, FreddyBEN SHALOM, Niv
    • ZINGER, FreddyBEN SHALOM, Niv
    • A61J1/20
    • A61J1/2096A61J1/201A61J1/2055A61M5/162A61M39/223
    • Liquid drug delivery device includes a housing with a syringe port for sealingly receiving a syringe having a syringe tip ending at a widened distal tip, a vial adapter port with a vial adapter for snap fit receiving a vial, and a drug administration port for administering a liquid drug. The vial adapter is intended to be rotationally detached after a mixing procedure for discarding together with a spent vial. The syringe port additionally includes a single use locking mechanism for securing the syringe to preclude inadvertent syringe detachment under normal use including agitation for reconstitution purposes. The drug administration port has a distal tip preferably similar to a syringe's widened distal tip for the same purpose of preventing conventional needles with a female Luer connector being slidingly mounted thereon.
    • 液体药物输送装置包括具有注射器端口的壳体,用于密封地接收具有终止于加宽的远端尖端的注射器末端的注射器,具有用于卡扣配合的小瓶适配器的小瓶适配器端口接纳小瓶,以及用于施用 液体药物。 小瓶适配器旨在在混合程序之后旋转分离,以与废样品瓶一起丢弃。 注射器端口另外包括用于固定注射器的单次使用的锁定机构,以防止在正常使用下的无意的注射器分离,包括用于重建目的的搅动。 药物给药口具有优选类似于注射器加宽的远侧末端的远端,用于防止在其上滑动地安装有母Luer连接器的常规针。