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1. 发明公开

EP2047498A1 METHOD FOR STORING AND REACTING IONS IN A MASS SPECTROMETER 审中-公开
标题翻译：一种用于在质谱仪蓄光和应对BY ION
公开(公告)号：EP2047498A1
公开(公告)日：2009-04-15
申请号：EP07763829.4
申请日：2007-06-28
申请人： MDS Analytical Technologies, a business unit of MDS INC., doing business through its SCIEX Division , Applied Biosystems Inc.
发明人： THOMSON, Bruce
IPC分类号： H01J49/36 , H01J49/06
CPC分类号： H01J49/063 , H01J49/0072 , Y10T436/24
摘要： A method of analyzing ions is provided having a first ion guide with first and second ends and introducing a first group of ions and a second group of ions of opposite polarity into the first ion guide, and applying an RF voltage potential to the first ion guide for confining the first and second groups of ions radially within the first ion guide. A first trapping barrier is provided to the first end of the first ion guide for trapping the first group of ions within the first ion guide and a second trapping barrier is provided to the second end of the first ion guide for trapping the second group of ions within the first ion guide and an axial field is provided for pushing the first group of ions toward the first trapping barrier and pushing the second group of ions toward the second trapping barrier.

2. 发明公开

EP2047244A1 METHOD OF OPERATING A MASS SPECTROMETER TO PROVIDE RESONANT EXCITATION ION TRANSFER 审中-公开
标题翻译：一种用于操作质谱仪共振激发离子运输
公开(公告)号：EP2047244A1
公开(公告)日：2009-04-15
申请号：EP07800421.5
申请日：2007-07-17
申请人： MDS Analytical Technologies, a business unit of MDS INC., doing business through its SCIEX Division , Applied Biosystems Inc.
发明人： THOMSON, Bruce , HAGER, Jim
IPC分类号： G01N30/72 , H01J49/10 , H01J49/40
CPC分类号： H01J49/4225 , H01J49/004 , H01J49/4265 , H01J49/4285
摘要： A method of operating a mass spectrometer having a rod set is provided. The rod set has a first end, a second end opposite to the first end, and a longitudinal axis extending between the first end and the second end. The method comprises a) admitting ions into the rod set; b) trapping at least some of the ions in the rod set by i) producing a first barrier field at a first end member adjacent to the first end of the rod set, ii) producing a second barrier field at a second end member adjacent to the second end of the rod set, and iii) providing an aggregate field comprising an RF field between the rods of the rod set; c) selecting a first selected mass to charge ratio of a first group of ions in the ions; d) determining a first excitement level of a selected characteristic of the aggregate field for the first group of ions; e) adjusting the selected characteristic of the aggregate field to the first excitement level to resonantly excite the first group of ions to mass selectively eject the first group of ions from the rod set past the barrier field; and, f) maintaining the selected characteristic of the aggregate field at the first excitement level during an excitement time interval wherein the excitation time interval is at least 1 millisecond.

3. 发明申请

WO2008009108A1 METHOD OF OPERATING A MASS SPECTROMETER TO PROVIDE RESONANT EXCITATION ION TRANSFER 审中-公开
标题翻译：操作质谱仪以提供共振激发离子传输的方法
公开(公告)号：WO2008009108A1
公开(公告)日：2008-01-24
申请号：PCT/CA2007/001256
申请日：2007-07-17
申请人： MDS ANALYTICAL TECHNOLOGIES, A BUSINESS UNIT OF MDS INC., DOING BUSINESS THROUGH ITS SCIEX DIVISION , APPLERA CORPORATION , THOMSON, Bruce , HAGER, Jim
发明人： THOMSON, Bruce , HAGER, Jim
IPC分类号： G01N30/72 , H01J49/10 , H01J49/40
CPC分类号： H01J49/4225 , H01J49/004 , H01J49/4265 , H01J49/4285
摘要： A method of operating a mass spectrometer having a rod set is provided. The rod set has a first end, a second end opposite to the first end, and a longitudinal axis extending between the first end and the second end. The method comprises a) admitting ions into the rod set; b) trapping at least some of the ions in the rod set by i) producing a first barrier field at a first end member adjacent to the first end of the rod set, ii) producing a second barrier field at a second end member adjacent to the second end of the rod set, and iii) providing an aggregate field comprising an RF field between the rods of the rod set; c) selecting a first selected mass to charge ratio of a first group of ions in the ions; d) determining a first excitement level of a selected characteristic of the aggregate field for the first group of ions; e) adjusting the selected characteristic of the aggregate field to the first excitement level to resonantly excite the first group of ions to mass selectively eject the first group of ions from the rod set past the barrier field; and, f) maintaining the selected characteristic of the aggregate field at the first excitement level during an excitement time interval wherein the excitation time interval is at least 1 millisecond.
摘要翻译：提供了具有棒组的操作质谱仪的方法。杆组具有第一端，与第一端相对的第二端和在第一端和第二端之间延伸的纵向轴线。该方法包括：a）将离子进入棒组; b）通过以下步骤捕获所述棒组中的至少一些离子：i）在与所述棒组的第一端相邻的第一端构件处产生第一屏障场，ii）在邻近所述杆组的第二端构件处产生第二屏障场所述杆组的第二端，以及iii）提供包括所述杆组的杆之间的RF场的聚集场; c）选择离子中的第一组离子的第一选择质量与电荷比; d）确定第一组离子的聚集场的选定特征的第一兴奋度; e）将聚集场的所选特征调整到第一兴奋水平以共振地激发第一组离子以质量选择性地从穿过屏障场的棒组中弹出第一组离子; 以及f）在所述激发时间间隔至少为1毫秒的兴奋时间间隔期间将所述聚集场的选定特性保持在所述第一兴奋度水平。

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