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1. 发明申请

WO0134835A3 METHOD FOR THE PRODUCTION OF BIOPOLYMERS WITH MODIFIED PROPERTIES 审中-公开
标题翻译：用于生产具有改性特性的生物聚合物的方法
公开(公告)号：WO0134835A3
公开(公告)日：2002-01-10
申请号：PCT/EP0011049
申请日：2000-11-08
申请人： MAX PLANCK GESELLSCHAFT , DIREVO BIOTECH AG
发明人： KOLTERMANN ANDRE , KETTLING ULRICH , EIGEN MANFRED
IPC分类号： C12N15/09 , C12Q1/68 , C12N15/10
CPC分类号： C12N15/1027
摘要： A method for the production of biopolymers with modified properties as well as a kit containing instructions for carrying out said method are described.
摘要翻译：描述了具有改进性质的生物聚合物的制备方法以及包含用于实施所述方法的说明书的试剂盒。

2. 发明专利

CA2390867A1 METHOD FOR THE PRODUCTION OF BIOPOLYMERS WITH MODIFIED PROPERTIES 未知
公开(公告)号：CA2390867A1
公开(公告)日：2001-05-17
申请号：CA2390867
申请日：2000-11-08
申请人： DIREVO BIOTECH AG , MAX PLANCK GESELLSCHAFT
发明人： EIGEN MANFRED , KETTLING ULRICH , KOLTERMANN ANDRE
IPC分类号： C12N15/09 , C12N15/10 , C12Q1/68
摘要： A method for the production of biopolymers with modified properties as well as a kit containing instructions for carrying out said method are described.

3. 发明专利

AU783823B2 Method for the production of biopolymers with modified properties 未知
公开(公告)号：AU783823B2
公开(公告)日：2005-12-08
申请号：AU1520101
申请日：2000-11-08
申请人： MAX PLANCK GESELLSCHAFT , DIREVO BIOTECH AG
发明人： KOLTERMANN ANDRE , KETTLING ULRICH , EIGEN MANFRED
IPC分类号： C12N15/09 , C12N15/10 , C12Q1/68
摘要： A method for the production of biopolymers with modified properties wherein at least one cycle comprising the following steps is completed:(a) providing a population of single-stranded polynucleotide molecules, wherein individual polynucleotide molecules comprise homologous and heterologous sequence segments and wherein individual ones of said single-stranded polynucleotide molecules can form double-stranded polynucleotide molecules with other ones of said single-stranded polynucleotide molecules within said population;(b) forming double-stranded polynucleotide molecules from the population of single-stranded polynucleotide molecules provided according to step (a) comprising double-stranded polynucleotide molecules with different heterologous sequence segments;(c) partially and exonucleolytically degrading the single-strands of the double-stranded polynucleotide molecules produced according to step (b); and(d) temple-directed single-stand synthesizing the degraded ends of the partially degraded double strand produced according to step (c),wherein steps (c) and (d) may be carried out sequentially or contemporaneously.

4. 发明专利

DE19953854C2 未知
公开(公告)号：DE19953854C2
公开(公告)日：2002-01-17
申请号：DE19953854
申请日：1999-11-09
申请人： MAX PLANCK GESELLSCHAFT , DIREVO BIOTECH AG
发明人： KOLTERMANN ANDRE , KETTLING ULRICH , EIGEN MANFRED
IPC分类号： C12N15/09 , C12N15/10 , C12Q1/68 , C12P19/34 , C07H1/00
摘要： A method for the production of biopolymers with modified properties wherein at least one cycle comprising the following steps is completed:(a) providing a population of single-stranded polynucleotide molecules, wherein individual polynucleotide molecules comprise homologous and heterologous sequence segments and wherein individual ones of said single-stranded polynucleotide molecules can form double-stranded polynucleotide molecules with other ones of said single-stranded polynucleotide molecules within said population;(b) forming double-stranded polynucleotide molecules from the population of single-stranded polynucleotide molecules provided according to step (a) comprising double-stranded polynucleotide molecules with different heterologous sequence segments;(c) partially and exonucleolytically degrading the single-strands of the double-stranded polynucleotide molecules produced according to step (b); and(d) temple-directed single-stand synthesizing the degraded ends of the partially degraded double strand produced according to step (c),wherein steps (c) and (d) may be carried out sequentially or contemporaneously.

5. 发明专利

AT277200T 未知
公开(公告)号：AT277200T
公开(公告)日：2004-10-15
申请号：AT00977514
申请日：2000-11-08
申请人： MAX PLANCK GESELLSCHAFT , DIREVO BIOTECH AG
发明人： KOLTERMANN ANDRE , KETTLING ULRICH , EIGEN MANFRED
IPC分类号： C12N15/09 , C12N15/10 , C12Q1/68
摘要： A method for the production of biopolymers with modified properties wherein at least one cycle comprising the following steps is completed:(a) providing a population of single-stranded polynucleotide molecules, wherein individual polynucleotide molecules comprise homologous and heterologous sequence segments and wherein individual ones of said single-stranded polynucleotide molecules can form double-stranded polynucleotide molecules with other ones of said single-stranded polynucleotide molecules within said population;(b) forming double-stranded polynucleotide molecules from the population of single-stranded polynucleotide molecules provided according to step (a) comprising double-stranded polynucleotide molecules with different heterologous sequence segments;(c) partially and exonucleolytically degrading the single-strands of the double-stranded polynucleotide molecules produced according to step (b); and(d) temple-directed single-stand synthesizing the degraded ends of the partially degraded double strand produced according to step (c),wherein steps (c) and (d) may be carried out sequentially or contemporaneously.

6. 发明专利

DE19953854A1 未知
公开(公告)号：DE19953854A1
公开(公告)日：2001-06-28
申请号：DE19953854
申请日：1999-11-09
申请人： MAX PLANCK GESELLSCHAFT , DIREVO BIOTECH AG
发明人： KOLTERMANN ANDRE , KETTLING ULRICH , EIGEN MANFRED
IPC分类号： C12N15/09 , C12N15/10 , C12Q1/68 , C12P19/34 , C07H1/00
摘要： A method for the production of biopolymers with modified properties wherein at least one cycle comprising the following steps is completed:(a) providing a population of single-stranded polynucleotide molecules, wherein individual polynucleotide molecules comprise homologous and heterologous sequence segments and wherein individual ones of said single-stranded polynucleotide molecules can form double-stranded polynucleotide molecules with other ones of said single-stranded polynucleotide molecules within said population;(b) forming double-stranded polynucleotide molecules from the population of single-stranded polynucleotide molecules provided according to step (a) comprising double-stranded polynucleotide molecules with different heterologous sequence segments;(c) partially and exonucleolytically degrading the single-strands of the double-stranded polynucleotide molecules produced according to step (b); and(d) temple-directed single-stand synthesizing the degraded ends of the partially degraded double strand produced according to step (c),wherein steps (c) and (d) may be carried out sequentially or contemporaneously.

7. 发明专利

CA2390867C METHOD FOR THE PRODUCTION OF BIOPOLYMERS WITH MODIFIED PROPERTIES 未知
公开(公告)号：CA2390867C
公开(公告)日：2009-10-27
申请号：CA2390867
申请日：2000-11-08
申请人： DIREVO BIOTECH AG , MAX PLANCK GESELLSCHAFT
发明人： EIGEN MANFRED , KOLTERMANN ANDRE , KETTLING ULRICH
IPC分类号： C12N15/09 , C12Q1/68 , C12N15/10
摘要： A method for the production of biopolymers with modified properties as well as a kit containing instructions for carrying out said method are described.

8. 发明专利

ES2223613T3 METODO PARA LA PRODUCCION DE BIOPOLIMEROS CON PROPIEDADES MODIFICADAS. 未知
公开(公告)号：ES2223613T3
公开(公告)日：2005-03-01
申请号：ES00977514
申请日：2000-11-08
申请人： MAX PLANCK GESELLSCHAFT , DIREVO BIOTECH AG
发明人： KOLTERMANN ANDRE , KETTLING ULRICH , EIGEN MANFRED
IPC分类号： C12N15/10 , C12Q1/68 , C12N15/09
摘要： Un método para la producción de moléculas polinucleotídicas con propiedades modificadas, en el que se completa al menos un ciclo que comprende las siguientes etapas: (a) proporcionar una población de moléculas polinucleotídicas monocatenarias, en la que los polinucleótidos individuales de dicha población tienen segmentos de la secuencia homólogos y heterólogos, y en la que la población también contiene cadenas que son completa o parcialmente complementarias con estas cadenas monocatenarias; (b) la formación de moléculas polinucleotídicas bicatenarias de la población de las moléculas polinucleotídicas monocatenarias proporcionada según la etapa (a), que comprenden cadenas bicatenarias con diferentes segmentos de la secuencias heterólogos; (c) la degradación monocatenaria exonucleolítica parcial de las moléculas polinucleotídicas bicatenarias producidas según la etapa (b); y (d) la extensión dirigida por moldes de los extremos degradados de la cadena bicatenaria parcialmente degradada producida según la etapa (c), en el que las etapas (c) y (d) pueden realizarse posterior o contemporáneamente.

9. 发明专利

DK1230390T3 未知
公开(公告)号：DK1230390T3
公开(公告)日：2004-12-13
申请号：DK00977514
申请日：2000-11-08
申请人： MAX PLANCK GESELLSCHAFT , DIREVO BIOTECH AG
发明人： EIGEN MANFRED , KOLTERMANN ANDRE , KETTLING ULRICH
IPC分类号： C12N15/10 , C12Q1/68

10. 发明专利

DE60014150D1 未知
公开(公告)号：DE60014150D1
公开(公告)日：2004-10-28
申请号：DE60014150
申请日：2000-11-08
申请人： MAX PLANCK GESELLSCHAFT , DIREVO BIOTECH AG
发明人： KOLTERMANN ANDRE , KETTLING ULRICH , EIGEN MANFRED
IPC分类号： C12N15/09 , C12N15/10 , C12Q1/68
摘要： A method for the production of biopolymers with modified properties wherein at least one cycle comprising the following steps is completed:(a) providing a population of single-stranded polynucleotide molecules, wherein individual polynucleotide molecules comprise homologous and heterologous sequence segments and wherein individual ones of said single-stranded polynucleotide molecules can form double-stranded polynucleotide molecules with other ones of said single-stranded polynucleotide molecules within said population;(b) forming double-stranded polynucleotide molecules from the population of single-stranded polynucleotide molecules provided according to step (a) comprising double-stranded polynucleotide molecules with different heterologous sequence segments;(c) partially and exonucleolytically degrading the single-strands of the double-stranded polynucleotide molecules produced according to step (b); and(d) temple-directed single-stand synthesizing the degraded ends of the partially degraded double strand produced according to step (c),wherein steps (c) and (d) may be carried out sequentially or contemporaneously.

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