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1. 发明申请

WO2007084648A2 MIXED 4?6 PROCYANIDIN DIMERS AND THEIR USE 审中-公开
标题翻译：混合4？6亚胺二酮及其用途
公开(公告)号：WO2007084648A2
公开(公告)日：2007-07-26
申请号：PCT/US2007001397
申请日：2007-01-19
申请人： MARS INC , SCHMITZ HAROLD H , ROBBINS REBECCA J , KWIK-URIBE CATHERINE L
发明人： SCHMITZ HAROLD H , ROBBINS REBECCA J , KWIK-URIBE CATHERINE L
IPC分类号： A61K31/7048
CPC分类号： A61K31/7048
摘要： This invention relates to compositions, and methods of use thereof, containing mixed 4?6 procyam'din dimers and derivatives thereof, for inducing vasodilation, for example for treating or preventing diseases or disorders of the vascular system (e.g. hypertension, cardiovascular disease, and stroke).
摘要翻译：本发明涉及组合物及其使用方法，其含有混合的4×6原花青素二聚体及其衍生物，用于诱导血管舒张，例如用于治疗或预防血管系统的疾病或病症（例如高血压，心血管疾病和行程）。

2. 发明申请

WO2007002851A2 THERMALLY-PROCESSED COCOA PRODUCTS USEFUL FOR VASCULAR HEALTH IMPROVEMENT 审中-公开
标题翻译：用于血管健康改善的热处理COCOA产品
公开(公告)号：WO2007002851A2
公开(公告)日：2007-01-04
申请号：PCT/US2006025422
申请日：2006-06-29
申请人： MARS INC , SCHMITZ HAROLD H , KWIK-URIBE CATHERINE L , HAMMERSTONE JOHN F , KELM MARK A , ROBBINS REBECCA J
发明人： SCHMITZ HAROLD H , KWIK-URIBE CATHERINE L , HAMMERSTONE JOHN F , KELM MARK A , ROBBINS REBECCA J
IPC分类号： C07D311/22 , A61K31/353
CPC分类号： A61K31/353 , A23G1/0009 , A23G1/30 , A23G1/56 , A23L33/105 , A61K36/185
摘要： The invention relates to compositions containing polyphenols such as flavanols, procyanidins, and derivatives thereof obtainable by thermally treating the polyphenols in an aqueous solution, and to compositions comprising epimers of flavanols, procyanidins, and derivatives thereof, and methods of therapeutic or prophylactic treatment of NO-responsive diseases or disorders using the same. The invention also relates to thermally-processed cocoa powders and cocoa extracts characterized by an altered monomelic and oligomeric profile where the total amount of epicatechin and catechin is unchanged, where new dimers are present, and where oligomers higher than the trimers are absent.
摘要翻译：本发明涉及含有多酚的组合物，例如黄烷醇，原花青素及其衍生物，其通过热处理水溶液中的多酚得到，以及包含黄烷醇，原花青素及其衍生物的差向异构体的组合物，以及治疗或预防性治疗NO 反应性疾病或使用其的疾病。本发明还涉及热加工的可可粉和可可提取物，其特征在于改变的单体和寡聚型，其中表儿茶素和儿茶素的总量不变，其中存在新的二聚体，并且其中不存在高于三聚体的低聚物。

3. 发明申请

WO2007041514A2 PROCESS FOR SELECTIVELY EXTRACTING PROCYANIDINS 审中-公开
标题翻译：选择性提取原花青素的方法
公开(公告)号：WO2007041514A2
公开(公告)日：2007-04-12
申请号：PCT/US2006038483
申请日：2006-10-03
申请人： MARS INC , ROBBINS REBECCA J , KELM MARK A , MUNAFO JOHN P
发明人： ROBBINS REBECCA J , KELM MARK A , MUNAFO JOHN P
IPC分类号： C07D405/14 , C07H15/00
CPC分类号： C07D311/62 , C07H15/00
摘要： A process is described for selectively extracting cocoa procyanidins from an aqueous mixture of cocoa polyphenols by using a particular sequence of solvents to extract selected procyanidin monomers and/or oligomers. The solvents are n-butyl acetate, ethyl acetate, methyl acetate, diethyl ether or mixtures of methyl acetate and diethyl ether. Preferably, the aqueous mixture of cocoa polyphenols is first extracted with n-butyl acetate. The mixtures of methyl acetate and diethyl ether are between 25:75 and 75:25 (v/v).
摘要翻译：描述了一种用于通过使用特定顺序的溶剂从可可多酚的含水混合物中选择性提取可可矢车菊苷配质以提取选定的矢车菊苷配基单体和/或低聚物的方法。溶剂是乙酸正丁酯，乙酸乙酯，乙酸甲酯，乙醚或乙酸甲酯和乙醚的混合物。优选地，可可多酚的含水混合物首先用乙酸正丁酯萃取。乙酸甲酯和二乙醚的混合物在25:75和75:25（v / v）之间。

4. 发明申请

WO2014152478A2 NATURAL BLUE ANTHOCYANIN-CONTAINING COLORANTS 审中-公开
标题翻译：天然蓝色含鸟嘌呤的着色剂
公开(公告)号：WO2014152478A2
公开(公告)日：2014-09-25
申请号：PCT/US2014027385
申请日：2014-03-14
申请人： MARS INC , OHIO STATE UNIVSITY
发明人： ROBBINS REBECCA J , JOHNSON J CHRISTOPHER , COLLINS THOMAS M , AHMADIANI NEDA , GIUSTI M MONICA
IPC分类号： C09B61/00
CPC分类号： A23L1/2751 , A23G3/343 , A23G3/54 , A23L5/43 , C09B61/00
摘要： The present invention is directed to natural blue anthocyanin-containing colorants comprising fractions of anthocyanin molecules separated from anthocyanin-containing vegetable and fruit juices and extracts. Anthocyanin fractions are separated at a select pH based on differences in polarity of the anthocyanin molecules in the anthocyanin-containing vegetable and fruit juices and extracts. The invention is directed to the anthocyanin fractions providing color characteristics similar to those provided by the synthetic blue colorant, FD&C Blue No. 1. The present invention is also directed to natural green colorants comprising the natural blue anthocyanin-containing colorant and a natural yellow colorant. The present invention is further directed to edible products comprising the natural blue anthocyanin-containing colorants.
摘要翻译：本发明涉及天然蓝色花色素苷着色剂，其包含从含花青素的蔬菜和果汁以及提取物中分离出的花青素分子的馏分。根据含花青素苷的蔬菜和果汁以及提取物中花色素苷分子的极性差异，在选定的pH下分离花青素部分。本发明涉及提供与由合成蓝色着色剂FD＆C蓝色1号提供的颜色特征相似的颜色特征的花青素部分。本发明还涉及天然绿色着色剂，其包含天然蓝色花青素着色剂和天然黄色着色剂。本发明还涉及包含天然蓝色花色素苷着色剂的可食用产品。

5. 发明申请

WO2014152417A3 METHOD OF ISOLATING BLUE ANTHOCYANIN FRACTIONS 审中-公开
标题翻译：分离蓝色花青素组分的方法
公开(公告)号：WO2014152417A3
公开(公告)日：2014-11-20
申请号：PCT/US2014027319
申请日：2014-03-14
申请人： MARS INC , UNIV OHIO STATE
发明人： ROBBINS REBECCA J , JOHNSON J CHRISTOPHER , COLLINS THOMAS M , AHMADIANI NEDA , GIUSTI M MONICA
IPC分类号： C09B61/00 , A23L1/275 , C07H17/065
CPC分类号： C09B61/00 , A23L2/04 , A23L2/58 , A23L5/43 , A23V2002/00 , B01D15/362 , B01D15/426 , C07D311/58
摘要： The present invention is directed to a method of isolating fractions of anthocyanin molecules from anthocyanin-containing vegetable and fruit juices and extracts, or combinations thereof, at a select pH based on differences in polarity of the anthocyanin molecules in the anthocyanin-containing vegetable and fruit juices and extracts.
摘要翻译：本发明涉及一种从含花色素苷的蔬菜和果汁以及提取物或其组合中在基于含花色素苷的蔬菜和水果中的花色素苷分子的极性差异的选择pH下分离花青素分子的部分的方法果汁和提取物。

6. 发明公开

EP3027040A4 ORANGE AND RED ANTHOCYANIN-CONTAINING COLORANTS 有权
标题翻译：橙色和红色染料ANTHOCYANINHALTIGE
公开(公告)号：EP3027040A4
公开(公告)日：2017-03-22
申请号：EP14832980
申请日：2014-07-31
申请人： MARS INC
发明人： ROBBINS REBECCA J
IPC分类号： A23G3/32 , A23G3/34 , A23G3/42 , A23G3/54 , A23L5/40 , A23L5/43 , A23P20/10
CPC分类号： A23G3/343 , A23G3/32 , A23G3/42 , A23G3/54 , A23L5/43 , A23P20/10 , A23V2002/00
摘要： The present application is directed to a method of hard pan coating an edible core, a sucrose-based, hard panned coating, and a hard panned confection comprising an edible core coated with the same. The sucrose-based, hard panned coating comprises sucrose and a pH-adjusted red radish anthocyanin-containing colorant, is substantially crystalline, and has a red or orange hue described by a CIELCH color space h° coordinate of from about 15° to about 70°. In some embodiments, the coating further comprises a yellow colorant. The colorants are desirably naturally sourced to provide alternatives to synthetic colorants for coloring hard panned confectionery coatings in red or orange hues.

7. 发明公开

EP3027039A4 BROWN ANTHOCYANIN-CONTAINING COLORANT 有权
标题翻译：染料与BROWN花色素苷
公开(公告)号：EP3027039A4
公开(公告)日：2017-01-18
申请号：EP14832936
申请日：2014-07-31
申请人： MARS INC
发明人： ROBBINS REBECCA J
IPC分类号： A23G3/32 , A23G3/42 , A23L5/40 , A23L5/43 , A23P20/10
CPC分类号： A23L1/2751 , A23G3/32 , A23G3/42 , A23L5/43 , A23P20/10 , A23V2002/00
摘要： The present application is directed to a method of hard pan coating an edible core, a sucrose-based, hard panned coating, and a hard panned confection comprising an edible core coated with the same. The sucrose-based, hard panned coating comprises sucrose and a pH-adjusted purple carrot anthocyanin-containing colorant, is substantially crystalline, and has a brown hue described by a CIELCH color space h° coordinate of from about 0° to about 70°. In some embodiments, the coating further comprises a yellow colorant. The colorants are desirably naturally sourced to provide alternatives to synthetic colorants for coloring hard panned confectionery coatings in brown hues.

8. 发明专利

CA2903474C STABILIZATION OF NATURAL BLUE ANTHOCYANIN-CONTAINING COLORANTS AND PRODUCTS MADE 未知
公开(公告)号：CA2903474C
公开(公告)日：2021-04-20
申请号：CA2903474
申请日：2014-03-10
申请人： MARS INC
发明人： ROBBINS REBECCA J
IPC分类号： A23G3/34 , A23G3/54
摘要： The present invention is directed to a hard panned coating comprising a natural blue anthocyanin-containing colorant, a hard panned confection coated with the same, and a method of hard pan coating an edible product center with the coating such that the color provided by the natural blue anthocyanin-containing colorant to the coating is stabilized.

9. 发明专利

BR112016001286A2 corante que contém antocianina marrom 未知
公开(公告)号：BR112016001286A2
公开(公告)日：2017-07-25
申请号：BR112016001286
申请日：2014-07-31
申请人： MARS INC
发明人： ROBBINS REBECCA J
IPC分类号： A23L5/40

10. 发明专利

CA2904647C NATURAL BLUE ANTHOCYANIN-CONTAINING COLORANTS 未知
公开(公告)号：CA2904647C
公开(公告)日：2016-07-26
申请号：CA2904647
申请日：2014-03-14
申请人： MARS INC , UNIV OHIO STATE
发明人： ROBBINS REBECCA J , JOHNSON J CHRISTOPHER , COLLINS THOMAS M , AHMADIANI NEDA , GIUSTI M MONICA
IPC分类号： C09B61/00 , C07H17/065
摘要： The present invention is directed to natural blue anthocyanin-containing colorants comprising fractions of anthocyanin molecules separated from anthocyanin-containing vegetable and fruit juices and extracts. Anthocyanin fractions are separated at a select pH based on differences in polarity of the anthocyanin molecules in the anthocyanin-containing vegetable and fruit juices and extracts. The invention is directed to the anthocyanin fractions providing color characteristics similar to those provided by the synthetic blue colorant, FD&C Blue No. 1. The present invention is also directed to natural green colorants comprising the natural blue anthocyanin-containing colorant and a natural yellow colorant. The present invention is further directed to edible products comprising the natural blue anthocyanin-containing colorants.

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