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    • 6. 发明申请
    • PYRAN DERIVATIVES, PROCESS OF PREPARATION AND USE THEREOF IN PERFUMERY AND FLAVOURING
    • PYRAN衍生物,其制备方法及其在造纸及其中的应用
    • WO2008065181A2
    • 2008-06-05
    • PCT/EP2007063051
    • 2007-11-30
    • MANE FILS VPLESSIS CAROLINEMANE JEAN
    • PLESSIS CAROLINEMANE JEAN
    • C07D309/04A23L27/20A61K8/49A61Q13/00C07D309/10C07D309/18
    • C07D309/04A23L27/2052A61K8/4973A61Q5/00A61Q5/02A61Q9/02A61Q11/00A61Q15/00A61Q19/00A61Q19/002A61Q19/10C07D309/10C07D309/18
    • Pyran derivatives of general formula (I) wherein Y is a 5-, 6- or 7-membered ring, preferably a 5- membered ring, methyl or ethyl mono- or polysubstituted, and optionally unsaturated, and R1, R2, R3, R4 are, each independently, a hydrogen atom or a linear or branched C 1-5 alkyl or C 2-5 alkenyl group, and X is present or absent; when X is present, R5, R6, R7, R8, R9 are all present, and X is a hydrogen atom or an OZ group, wherein Z is a hydrogen atom or a R10 group or a C(O)R10 group; when X is absent, a double bond involving the carbon atom at the 4 position is present and R7, R8 and R9 are present, and one of R5 or R6 is present and the other one is absent, or R5, R6, and R7 are present, and one of R8 or R9 is present and the other one is absent, or R7 is a =C (R11) (R12) group and R5, R6, R8, R9 are present; and when they are present, each of R5-R12 group is, independently, a hydrogen atom or a linear or branched C 1-5 alkyl or C 2-5 alkenyl group; and use of at least one pyran derivative of formula (I) as flavouring or fragrant agent.
    • 通式(I)的吡喃衍生物,其中Y是5-,6-或7-元环,优选5-元环,甲基或乙基单或多取代且任选不饱和,且R 1,R 2,R 3,R 4 各自独立地为氢原子或直链或支链C 1-5烷基或C 2-5烯基,X存在或不存在; 当X存在时,R5,R6,R7,R8,R9全部存在,X为氢原子或OZ基团,其中Z为氢原子或R10基团或C(O)R10基团; 当X不存在时,存在涉及4位碳原子的双键并且存在R7,R8和R9,并且存在R5或R6中的一个,另一个不存在,或者R5,R6和R7是 存在,R8或R9中的一个存在,另一个不存在,或者R7是a = C(R11)(R12)基团,R5,R6,R8,R9存在; 并且当它们存在时,R 5 -R 12基团各自独立地为氢原子或直链或支链C 1-5烷基或C 2-5烯基 ; 并使用至少一种式(I)的吡喃衍生物作为调味剂或芳香剂。