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1. 发明申请

WO2009026060A2 FLUID DRIVEN MEDICAL INJECTORS 审中-公开
标题翻译：流体驱动医用注射器
公开(公告)号：WO2009026060A2
公开(公告)日：2009-02-26
申请号：PCT/US2008072978
申请日：2008-08-13
申请人： MALLINCKRODT INC , WAGNER GARY S , FAGO FRANK M , STAATS PETER , BATTIATO DANE
发明人： WAGNER GARY S , FAGO FRANK M , STAATS PETER , BATTIATO DANE
IPC分类号： A61M5/145 , A61M5/142
CPC分类号： A61B5/055 , A61M5/007 , A61M5/14216 , A61M5/14228 , A61M5/14526 , A61M5/1454 , A61M5/16827 , A61M39/08 , A61M2005/14513
摘要： Some injectors of the invention may include a fluid drive responsive to pressure of a working fluid (e.g., liquid, pneumatic, or both) to impart a sequence of forces to drive a delivery device (e.g., a syringe) to deliver a medical fluid (e.g., a contrast agent, a radiopharmaceutical, a drug, or a combination thereof). Some injectors may include a multimedia tube configured to pass a working fluid (e.g., air) and a light signal (e.g., infrared). Some injectors may include a peristaltic drive responsive to pressure of a working fluid.
摘要翻译：本发明的一些注射器可以包括响应于工作流体（例如液体，气动或两者）的压力的流体驱动器，以施加一系列的力来驱动输送装置（例如，注射器）输送医用流体（例如造影剂，放射性药物，药物或其组合）。一些喷射器可以包括配置成通过工作流体（例如空气）和光信号（例如，红外线）的多媒体管。一些注射器可以包括响应于工作流体的压力的蠕动驱动器。

2. 发明申请

WO2007016172A2 ALIGNMENT ADAPTER FOR USE WITH A RADIOISOTOPE GENERATOR AND METHODS OF USING THE SAME 审中-公开
标题翻译：用于无线电发生器的对准适配器及其使用方法
公开(公告)号：WO2007016172A2
公开(公告)日：2007-02-08
申请号：PCT/US2006029057
申请日：2006-07-26
申请人： MALLINCKRODT INC , WAGNER GARY S , WILSON DAVID W , FAGO FRANK M , POLLARD JR RALPH E
发明人： WAGNER GARY S , WILSON DAVID W , FAGO FRANK M , POLLARD JR RALPH E
IPC分类号： G21G4/08 , G21F5/015
CPC分类号： G21G4/00 , G21F5/015 , G21Y2002/207 , G21Y2002/303 , G21Y2002/501 , G21Y2004/30
摘要： The invention, in one characterization, may be said to be directed to an alignment adapter that may be utilized in radioisotope elution procedures. In some embodiments, the alignment adaptor may be utilized to at least assist in aligning various components of an elution system. For example, in some embodiments, the alignment adaptor may be utilized to at least generally assist in aligning an aperture defined in a lid of the elution system and an elution needle of a radioisotope generator. In some embodiments, the alignment adaptor may be utilized to at least generally assist in aligning an elution assembly (e.g., elution shield housing an eluate vial) and an elution needle of a radioisotope generator. Further, in some embodiments, the alignment adaptor may be utilized to at least generally assist in aligning an eluant container (e.g., bottle of eluant) and a needle of a radioisotope generator.
摘要翻译：在一个表征中，本发明可以说是针对可用于放射性同位素洗脱程序的对准适配器。在一些实施方案中，对准适配器可用于至少有助于排列洗脱系统的各种组分。例如，在一些实施例中，对准适配器可以用于至少大体上有助于对齐限定在洗脱系统的盖子中的孔和放射性同位素发生器的洗脱针。在一些实施方案中，对准适配器可用于至少大体上有助于使洗脱组件（例如，洗脱屏蔽罩住洗脱液瓶）和放射性同位素发生器的洗脱针排列。此外，在一些实施例中，对准适配器可用于至少大体上有助于对齐洗脱液容器（例如，瓶的洗脱液）和放射性同位素发生器的针。

3. 发明申请

WO2007016171A3 RADIATION-SHIELDING ASSEMBLIES AND METHODS OF USING THE SAME 审中-公开
标题翻译：辐射屏蔽组件及其使用方法
公开(公告)号：WO2007016171A3
公开(公告)日：2007-06-07
申请号：PCT/US2006029056
申请日：2006-07-26
申请人： MALLINCKRODT INC , FAGO FRANK M , WILSON DAVID W , WAGNER GARY S , POLLARD RALPH E JR
发明人： FAGO FRANK M , WILSON DAVID W , WAGNER GARY S , POLLARD RALPH E JR
IPC分类号： G21F5/015
CPC分类号： G21F5/015 , Y10T29/49 , Y10T29/49826
摘要： In one characterization, the present invention relates to a radiation-shielding assembly for holding a container having a radioactive material disposed therein. The assembly may, at least in one regard, be referred to as an elution shield and/or a dispensing shield. The assembly includes a body at least partially defining a cavity. There is at least one opening through the body into the cavity. The assembly may include a cap that at least generally hinders escape of radiation from the assembly through the opening. The cap may be releasably attached to the body in one orientation and may establish non-attached engagement with the body in another orientation. The assembly may include an adjustable spacer system for adapting the assembly for use with containers having different heights.
摘要翻译：在一个表征中，本发明涉及一种用于保持放置有放射性材料的容器的辐射屏蔽组件。至少在一个方面，组件可以被称为洗脱屏蔽和/或分配屏蔽。组件包括至少部分地限定空腔的主体。通过身体至少有一个开口进入腔体。组件可以包括帽，其至少通常阻止辐射通过开口从组件逃逸。帽可以以一个取向可释放地附接到身体，并且可以在另一取向上与身体建立非附着的接合。组件可以包括可调节间隔器系统，用于使组件适应于具有不同高度的容器。

4. 发明申请

WO2006124775A3 RADIOPHARMACEUTICAL PIGS AND PORTABLE POWERED INJECTORS 审中-公开
标题翻译：放射性核素和便携式注射器
公开(公告)号：WO2006124775A3
公开(公告)日：2007-04-12
申请号：PCT/US2006018727
申请日：2006-05-16
申请人： MALLINCKRODT INC , WAGNER GARY S , FAGO FRANK M , GRISPO KEITH M , GIBSON CHAD M , LEWIS JOHN H , BAUSMITH WILLIAM E , HAYNES ELAINE E , WILSON DAVID W , ORTENZI VERNON D , BORGEMENKE ELAINE
发明人： WAGNER GARY S , FAGO FRANK M , GRISPO KEITH M , GIBSON CHAD M , LEWIS JOHN H , BAUSMITH WILLIAM E , HAYNES ELAINE E , WILSON DAVID W , ORTENZI VERNON D , BORGEMENKE ELAINE
IPC分类号： A61M5/178 , A61M5/145 , A61N5/10 , G01N23/10 , G01T7/02 , G21F5/015 , G21F5/018
CPC分类号： A61M5/14546 , A61M5/007 , A61M5/1456 , A61M5/16827 , A61M5/172 , A61M5/1785 , A61M2005/14506 , A61M2205/60 , A61M2205/6018 , G06K2017/009
摘要： Certain embodiments of the invention relate to a radiopharmaceutical system having a shielded cordless injector and various radiopharmaceutical pig and syringe structures that permit the syringe to remain in the pig during transportation and use of the syringe. In some embodiments, the shielded cordless injector may include an injector, a radiation shield disposed at least partially about the injector, a drive coupled to the injector, and an energy storage device coupled to the drive. The pig may have a computer with a display screen that displays a radioactivity level of a radiopharmaceutical and/or a desired (e.g., correct) unit dose volume of a radiopharmaceutical to be administered to a patient.
摘要翻译：本发明的某些实施例涉及具有屏蔽无绳注射器和各种放射性药物猪和注射器结构的放射性药物系统，其允许注射器在注射器的运输和使用期间保持在猪中。在一些实施例中，屏蔽无绳注射器可以包括注射器，至少部分地围绕注射器设置的辐射屏蔽，耦合到注射器的驱动器以及耦合到驱动器的能量存储装置。猪可以具有显示屏幕的计算机，其显示放射性药物的放射性水平和/或待给予患者的放射性药物的期望（例如，正确的）单位剂量体积。

5. 发明申请

WO2006044409A3 POWER INJECTION SYSTEM WITH POWERHEAD HAVING A DISPLAY 审中-公开
标题翻译：带电源的电源注入系统
公开(公告)号：WO2006044409A3
公开(公告)日：2006-07-06
申请号：PCT/US2005036566
申请日：2005-10-12
申请人： LIEBEL FLARSHEIM CO , SMALL JAMES R , BROOKS DAVID M , NEER CHARLES S , FAGO FRANK M , WAGNER GARY S , BORGEMENKE ELAINE , LAFFERTY SEAN
发明人： SMALL JAMES R , BROOKS DAVID M , NEER CHARLES S , FAGO FRANK M , WAGNER GARY S , BORGEMENKE ELAINE , LAFFERTY SEAN
IPC分类号： A61M5/145
CPC分类号： A61M5/14546 , A61M5/007 , A61M5/14566 , A61M5/16827 , A61M5/172 , A61M39/10 , A61M2205/3362 , A61M2205/3523 , A61M2205/3561 , A61M2205/3592 , A61M2205/50 , A61M2205/505 , A61M2205/6081
摘要： A dual head contrast media injection system performs a patency check or test injection, determining flow rate and/or flow volume from the programmed protocol. The tubing that connects syringes to a patient shares only a short common section near to the patient. Appropriate injection steps are taken to compensate for tubing elasticity. A wireless remote control and a touch screen control are provided, improving functionality and information delivery. The display brightness is controlled based on the ambient light, and the display panel includes a double swivel permitting re-orientation. The orientation of the display may also be controlled based on, e.g., the current step, the tilt angle of the powerhead, or a manual control. Furthermore, the display is customizable to identify the type of fluid (contrast, saline, etc.) on either side of the injector, to provide matched color coding, and to provide a folder/tab analogy for retrieving injection protocol parameters.
摘要翻译：双头造影剂注射系统执行通畅检查或测试注射，从编程的协议确定流量和/或流量。将注射器连接到患者的管道仅在患者附近共享一个短的共同部分。采取适当的注射步骤来补偿管道弹性。提供无线遥控器和触摸屏控制，改善功能和信息传递。基于环境光来控制显示亮度，并且显示面板包括允许重新定向的双重旋转。显示器的方向也可以基于例如当前步骤，动力头的倾斜角度或手动控制来控制。此外，显示器可定制以识别注射器两侧的流体类型（对比度，盐水等），以提供匹配的颜色编码，并提供用于检索注射方案参数的文件夹/片段类比。

6. 发明申请

WO2008076150A3 RADIATION SHIELDED SYRINGE ASSEMBLY 审中-公开
标题翻译：辐射屏蔽式注射器总成
公开(公告)号：WO2008076150A3
公开(公告)日：2008-11-06
申请号：PCT/US2007015948
申请日：2007-07-12
申请人： MALLINCKRODT INC , BRUCE JOHN K , FAGO FRANK M
发明人： BRUCE JOHN K , FAGO FRANK M
IPC分类号： A61M5/178 , G21F5/018
CPC分类号： A61M5/1785 , A61M2005/312 , A61M2005/3128 , G21F5/018
摘要： The application relates to radiation shielding (12) for use with radiopharmaceutical syringes (14). For example, in at least some regards, the invention relates to a syringe radiation shield that includes a sleeve (18) having a syringe receptacle defined therein to accommodate a barrel (26) of the syringe. In addition, this syringe radiation shield may also include a cover (20) having a plunger receptacle defined therein to accommodate a plunger of the syringe. The sleeve and the cover may be removably coupled wit one another so that the syringe can be housed within the syringe radiation shield, for example, during administration of a radiopharmaceutical from the syringe.
摘要翻译：本申请涉及用于放射性药物注射器（14）的辐射屏蔽（12）。例如，至少在某些方面，本发明涉及一种注射器辐射屏蔽，其包括套筒（18），其具有限定在其中的注射器容器，以容纳针筒的筒体（26）。此外，该注射器辐射屏蔽还可以包括具有限定在其中的柱塞接收器以容纳注射器的柱塞的盖（20）。套筒和盖可以彼此可移除地连接，使得注射器可以容纳在注射器辐射屏蔽内，例如在从注射器施用放射性药物期间。

7. 发明申请

WO2006130681A3 HEAT RETENTION DEVICES FOR SYRINGES AND USES THEREOF 审中-公开
标题翻译：用于注射的保温装置及其用途
公开(公告)号：WO2006130681A3
公开(公告)日：2007-04-26
申请号：PCT/US2006021108
申请日：2006-05-31
申请人： MALLINCKRODT INC , HYNES MICHAEL R , FAGO FRANK M
发明人： HYNES MICHAEL R , FAGO FRANK M
IPC分类号： A61M5/44
CPC分类号： A61M5/445 , A61M5/007 , A61M2205/3633
摘要： The present invention relates to heat-retaining syringe jackets for reducing the cooling rate of medical fluids held inside syringes and methods of using such syringe jackets. An exemplary syringe jacket of the invention may include a material that experiences a phase transition at a phase transition temperature. Additionally or alternatively, the exemplary syringe jacket may include a material exhibiting a high specific heat.
摘要翻译：本发明涉及用于降低保持在注射器内部的医疗液体的冷却速度的保温注射器护套和使用这种注射器护套的方法。本发明的示例性注射器套管可以包括在相变温度下经历相变的材料。另外或替代地，示例性注射器套管可以包括表现出高比热的材料。

8. 发明申请

WO2006124891A3 RADIOPHARMACEUTICAL CONTAINER HAVING SYRINGE CAPPER 审中-公开
标题翻译：带有疏水器的放射线吸收容器
公开(公告)号：WO2006124891A3
公开(公告)日：2007-01-18
申请号：PCT/US2006018905
申请日：2006-05-12
申请人： MALLINCKRODT INC , FAGO FRANK M
发明人： FAGO FRANK M
IPC分类号： G21F5/018 , A61M5/178
CPC分类号： G21F5/018 , A61M5/1785 , A61M5/3202 , A61M5/3204 , A61M2005/3215 , G21Y2002/207 , G21Y2002/208 , G21Y2002/304 , G21Y2002/50 , G21Y2004/30 , G21Y2004/40
摘要： According to at least one aspect, the present invention is directed a radiation-shielding container for holding a radiopharmaceutical syringe including a needle and a syringe cap covering the needle. This radiation-shielding container is equipped with what may be characterized as a cap retainer for selectively holding the syringe cap. The syringe cap may be held by the cap retainer so that an open end of the cap is oriented for insertion of the needle into the cap. The radiopharmaceutical syringe may be used to administer a radiopharmaceutical to a patient and thereby result in what is commonly referred to as a spent radiopharmaceutical syringe. The hypodermic needle of the spent radiopharmaceutical syringe may be inserted into the syringe cap while the syringe cap is held by the cap retainer to secure the syringe cap to the syringe.
摘要翻译：根据至少一个方面，本发明涉及一种用于保持放射性药剂注射器的放射线屏蔽容器，所述放射线药剂注射器包括针头和覆盖针的注射器帽。该辐射屏蔽容器配备有可以被表征为用于选择性地保持注射器盖的盖保持器。注射器帽可以由帽保持器保持，使得帽的开口端被定向成将针插入帽中。放射性药物注射器可用于向患者施用放射性药物，从而导致通常称为废弃放射性药物注射器。废弃的放射性药剂注射器的皮下注射针可以插入到注射器盖中，同时注射器帽由帽保持器保持以将注射器帽固定到注射器。

9. 发明申请

WO2005065747A2 CONTRAST CONTAINER HOLDER AND METHOD TO FILL SYRINGES 审中-公开
标题翻译：对比度容器固定器和填充注射器的方法
公开(公告)号：WO2005065747A2
公开(公告)日：2005-07-21
申请号：PCT/US2004041225
申请日：2004-12-09
申请人： MALLINCKRODT INC , FAGO FRANK M , BERGEN ROBERT , FARMER JAMES F
发明人： FAGO FRANK M , BERGEN ROBERT , FARMER JAMES F
IPC分类号： A61M5/00 , A61M5/145 , A61M5/178
CPC分类号： A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/1782 , A61M2209/082
摘要： The filling of a syringe can be performed at a faster rate using a filling sequence which expels air from the fill tube before filling the syringe. A similar method is used when changing contrast containers during a filling sequence to ensure that all the air is expelled from the fill tube before filling resumes with the new contrast container. Additionally, by including a contrast container holder that is affixed to an injector head and holds the container near the syringe tip, the filling sequence can be accomplished without requiring the operator to hold the contrast container during the sequence.
摘要翻译：注射器的填充可以使用在填充注射器之前从填充管排出空气的填充序列以更快的速率进行。在填充过程中更换造影剂容器时使用类似的方法，以确保在用新的造影剂容器重新填充之前，所有的空气都从填充管中排出。此外，通过包括固定在注射器头部上并将容器保持在注射器尖端附近的造影剂容器支架，可以在不需要操作者在顺序期间握住造影剂容器的情况下完成填充序列。

10. 发明申请

WO2010051205A3 MULTI-DOSE INJECTION SYSTEM 审中-公开
标题翻译：多剂量注射系统
公开(公告)号：WO2010051205A3
公开(公告)日：2010-10-07
申请号：PCT/US2009061568
申请日：2009-10-22
申请人： MALLINCKRODT INC , FAGO FRANK M
发明人： FAGO FRANK M
IPC分类号： A61M5/14
CPC分类号： A61M5/14546 , A61B6/548 , A61M5/007 , A61M5/1407 , A61M5/1413 , A61M5/14216 , A61M5/1456 , A61M5/162 , A61M5/16827 , A61M5/445 , A61M39/08 , A61M2005/14553 , A61M2205/12 , A61M2205/121 , A61M2205/3653 , A61M2205/6054
摘要： A multi-dose injection system (108) is disclosed that allows for safe and easy use of bulk containers, a multi-use tubing set (110), and syringes (86a, 86b) across multiple patients. The bulk containers may include a saline bottle (118) and a contrast bottle (120) for administration to a series of patients undergoing imaging procedures. The bottles (118, 120) may be fluidly connected to a cassette (114) that includes a saline valve (176) and a contrast valve (178) operable to control flow from the saline bottle (118) and the contrast bottle (120), respectively. The cassette (114) may be fluidly interconnected to the multi-use tubing set (110) that is, in turn, fluidly connected to syringes (86a, 86b) on a powerhead (50) and a patient-specific tubing set (112). The patient-specific tubing set (112) may be replaced between patients and may also serve to isolate the remainder of the multi-dose injection system (108) from contamination from bodily fluids.
摘要翻译：公开了多剂量注射系统（108），其允许跨多个患者安全且容易地使用散装容器，多用途管组（110）和注射器（86a，86b）。散装容器可以包括生理盐水瓶（118）和造影剂瓶（120），用于向正在进行成像程序的一系列患者施用。瓶（118,120）可以流体连接到包括盐水阀（176）和可操作以控制来自盐水瓶（118）和对比瓶（120）的流动的对比阀（178）的盒（114），分别。盒114可流体地互连到多用途管组110，多用管组110又流体地连接到动力头50上的注射器86a和86b以及患者专用管组112，。患者特异性管道组（112）可以在患者之间进行替换，并且还可以用于将多剂量注射系统（108）的其余部分与来自体液的污染隔离。

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