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1. 发明授权

US06703453B1 Condensation cross-linking polyurethane materials containing special aminosilanes, a method for the production thereof and their use 有权
标题翻译：包含特殊氨基硅烷的交联聚氨酯材料的缩合物，其生产方法及其用途
公开(公告)号：US06703453B1
公开(公告)日：2004-03-09
申请号：US10019578
申请日：2001-12-21
申请人： Lutz Schmalstieg , Ralf Lemmerz , Ulrich Walter , Oswald Wilmes
发明人： Lutz Schmalstieg , Ralf Lemmerz , Ulrich Walter , Oswald Wilmes
IPC分类号： C08G7718
CPC分类号： C09K3/10 , C07F7/1804 , C08G18/10 , C08G18/837 , C08G2190/00 , C08K5/3462 , C09D7/63 , C09K2200/0494 , C08G18/289
摘要： This invention relates to polyurethane compositions which cross-link via a silane polycondensation and contain at least one alkoxysilane-functional polyurethane, at least one basic filler, at least one reaction product of an aminosilane with a maleic or fumaric ester, at least one organometallic compound and optionally additional auxiliary substances, to a process for their preparation, and to their use.
摘要翻译：本发明涉及通过硅烷缩聚交联并含有至少一种烷氧基硅烷官能化聚氨酯，至少一种碱性填料，至少一种氨基硅烷与马来酸或富马酸酯的反应产物的聚氨酯组合物，至少一种有机金属化合物和任选的附加辅助物质，其制备方法及其用途。

2. 发明授权

US06599354B1 Piperazinone derivatives with alkoxysilane groups 失效
标题翻译：具有烷氧基硅烷基的哌嗪酮衍生物
公开(公告)号：US06599354B1
公开(公告)日：2003-07-29
申请号：US10019583
申请日：2001-12-21
申请人： Lutz Schmalstieg , Ralf Lemmerz , Ulrich Walter , Oswald Wilmes
发明人： Lutz Schmalstieg , Ralf Lemmerz , Ulrich Walter , Oswald Wilmes
IPC分类号： C08G7726
CPC分类号： C09K3/10 , C07F7/1804 , C08G18/10 , C08G18/837 , C08G2190/00 , C08K5/3462 , C09D7/63 , C09K2200/0494 , C08G18/289
摘要： The present invention relates to new alkoxysilane-functional piperazinone derivatives, a process for their production, as well as their use as additives in sealants, adhesives, lacquers or coating agents.
摘要翻译：本发明涉及新的烷氧基硅烷官能的哌嗪酮衍生物，其生产方法，以及它们作为密封剂，粘合剂，漆或涂层剂中的添加剂的用途。

3. 发明授权

US06626988B1 Phosphate-stabilized polyurethane materials, cross-linked by condensation, method for their production and use thereof 有权
标题翻译：磷酸酯稳定化的聚氨酯材料，通过冷凝交联，其制备方法及其用途
公开(公告)号：US06626988B1
公开(公告)日：2003-09-30
申请号：US09980941
申请日：2001-11-15
申请人： Lutz Schmalstieg , Ralf Lemmerz , Ulrich Walter , Alexander Eckhardt
发明人： Lutz Schmalstieg , Ralf Lemmerz , Ulrich Walter , Alexander Eckhardt
IPC分类号： C09D17504
CPC分类号： C08G18/10 , C08G2190/00 , C08G18/289
摘要： The invention relates to polyurethane materials, cross-linked by silane polycondensation, containing alkoxylsilane functional polyurethanes, alkaline fillers, phosphorous compounds aminosilanes, organometallic compounds and optionally additional auxiliary agents, to a method for their production and to the use thereof.
摘要翻译：本发明涉及通过硅烷缩聚交联的聚氨酯材料，其包含烷氧基硅烷官能聚氨酯，碱性填料，磷化合物氨基硅烷，有机金属化合物和任选的附加助剂，涉及其制备方法及其用途。

4. 发明授权

US5574124A Isocyanate prepolymers, a process for their preparation and their use 失效
标题翻译：异氰酸酯预聚物，其制备方法及其应用
公开(公告)号：US5574124A
公开(公告)日：1996-11-12
申请号：US510887
申请日：1995-08-03
申请人： Lutz Schmalstieg , Rainer Rettig , Ulrich Walter , Edwin R. Hortelano
发明人： Lutz Schmalstieg , Rainer Rettig , Ulrich Walter , Edwin R. Hortelano
IPC分类号： C08G18/10 , C08G18/12 , C08G18/40 , C08G18/44 , C09D175/00 , C09D175/04 , C09K3/10 , C08G18/42 , C07C269/02 , C08G18/48
CPC分类号： C09K3/1021 , C08G18/12 , C08G18/4018 , C08G18/44 , C08G2190/00
摘要： Isocyanate prepolymers having an NCO content of 1.5 to 5.0 wt. % and a monomeric diisocyanate content of less than 0.5 wt. % which are the reaction products ofA) aromatic or cycloaliphatic diisocyanates withB) mixtures ofB1) polyether polyols having a molecular weight of 1000 to 3000 andB2) polyester carbonate diols having a molecular weight of 700 to 3000,wherein components B1) and B2) are present in a weight ratio of 0.25:1 to 1.5:1;a process for the preparation of these isocyanate prepolymers by reacting the preceding starting materials at an NCO/OH equivalent ratio of at least 1.5:1 and optionally with subsequent removing unreacted monomeric diisocyanate by distillation; and the use of these isocyanate prepolymers as binders for sealing or coating compositions.
摘要翻译： NCO含量为1.5〜5.0重量％的异氰酸酯预聚物％，单体二异氰酸酯含量小于0.5wt。％，其为A）芳族或脂环族二异氰酸酯与B）B1）分子量为1000〜3000的聚醚多元醇和B2的混合物的反应产物）分子量为700〜3000的聚酯碳酸酯二醇，其中组分B1）和 B2）以0.25:1至1.5:1的重量比存在; 通过使前述原料以至少1.5:1的NCO / OH当量比反应制备这些异氰酸酯预聚物的方法，任选地随后通过蒸馏除去未反应的单体二异氰酸酯; 以及这些异氰酸酯预聚物作为粘合剂用于密封或涂布组合物的用途。

5. 发明授权

US08236809B2 Substituted 1,2,3-triazolopyrimidines for the inhibition of NAD(P)H oxidases and platelet activation 失效
标题翻译：用于抑制NAD（P）H氧化酶和血小板活化的取代的1,2,3-三唑并嘧啶
公开(公告)号：US08236809B2
公开(公告)日：2012-08-07
申请号：US11579999
申请日：2005-05-13
申请人： Frank Tegtmeier , Ulrich Walter , Reinhard Schinzel , Kirstin Wingler , Peter Scheurer , Harald Schmidt
发明人： Frank Tegtmeier , Ulrich Walter , Reinhard Schinzel , Kirstin Wingler , Peter Scheurer , Harald Schmidt
IPC分类号： C07D487/04 , A61K31/519 , A61P25/28 , A61P19/02 , A61P9/00 , A61P35/00 , A61P13/12
CPC分类号： C07D487/04
摘要： The invention relates to compounds of formula het-X-AB containing a N-heteroaryl moiety “het”, which is linked via X=sulfur to the 1,2,3-triazolo[4,5-d]pyrimidine-7-yl moiety AB of the formula (II). The invention also relates to a process for the preparation of said compounds and the use thereof in drugs for the treatment of NAD(P)H oxidase-related diseases and disorders and inhibition of platelet activation.
摘要翻译：本发明涉及含有N-杂芳基部分“het”的式het-X-AB的化合物，其通过X =硫与1,2,3-三唑并[4,5-d]嘧啶-7-基式（II）的部分AB。本发明还涉及制备所述化合物的方法及其用于治疗NAD（P）H氧化酶相关疾病和病症以及抑制血小板活化的药物中的用途。

6. 发明申请

US20100233069A1 METHOD AND SYSTEM FOR CONCENTRATING WASTE SULPHURIC ACIDS FROM NITRATION PROCESSES 有权
标题翻译：从硝化过程中浓缩废硫酸的方法和系统
公开(公告)号：US20100233069A1
公开(公告)日：2010-09-16
申请号：US12305902
申请日：2007-06-20
申请人： Ulrich Walter , Gottfried Dichtl
发明人： Ulrich Walter , Gottfried Dichtl
IPC分类号： C01B17/82 , B01D3/40
CPC分类号： C01B17/94 , B01D3/148 , B01D3/40
摘要： Disclosed is a method for recovering diluted waste sulfuric acid containing impurities from nitration processes, a highly concentrated nitric acid required in the nitration process being produced in association with the nitration process by means of extractive rectification with concentrated sulfuric acid which is re-concentrated in order to be reutilized. According to the inventive method, the waste sulfuric acid from the nitration process is fed to the top of a first, indirectly heated stripping column, optionally together with another waste sulfuric acid in the form of a DNT washing acid, and is divided into an overhead product containing nitric acid and nitro-organic compounds as well as a prepurified sulfuric acid in the bottom product. The prepurified sulfuric acid withdrawn from the bottom of the first stripping column is fed to the top of a second, serially connected additional indirectly heated stripping column, into the bottom zone of which another waste sulfuric acid is fed in the form of a diluted sulfuric acid recovered from the nitric acid concentration system such that the prepurified sulfuric acid from the first stripping column is further purified in the second stripping column and is preconcentrated along with the diluted sulfuric acid recovered from the extractive rectification of nitric acid.
摘要翻译：公开了一种从硝化过程中回收稀释的含有杂质的废硫酸的方法，硝化过程中所需的高浓度硝酸是通过与浓硫酸进行萃取精馏相结合的硝化过程制备的，该浓硫酸按顺序重新浓缩被重新利用。根据本发明的方法，将来自硝化过程的废硫酸进料到第一间接加热的汽提塔的顶部，任选地与另一种DNT洗涤酸形式的废硫酸一起分配成塔顶含有硝酸和硝基有机化合物的产品以及底部产物中的预硫化硫酸。将从第一汽提塔底部排出的预纯化硫酸进料到第二个连续连续的另外间接加热的汽提塔的顶部，进入其中另一个废硫酸以稀硫酸的形式进料的底部区域从硝酸浓缩系统回收，使得来自第一汽提塔的预纯化硫酸在第二汽提塔中进一步纯化，并与从硝酸萃取精馏中回收的稀硫酸一起预浓缩。

7. 发明授权

US06743835B2 Preparation of nondusting free-flowing pigment concentrates 失效
标题翻译：非阻燃自由流动颜料浓缩物的制备
公开(公告)号：US06743835B2
公开(公告)日：2004-06-01
申请号：US10006962
申请日：2001-12-05
申请人： Werner Schäfer , Manfred Scheiba , Stefan Stadtmüller , Markus Weimann , Karlheinz Rümpler , Ulrich Walter
发明人： Werner Schäfer , Manfred Scheiba , Stefan Stadtmüller , Markus Weimann , Karlheinz Rümpler , Ulrich Walter
IPC分类号： C08L302
CPC分类号： C09B67/0095 , C08J3/226 , C09B67/0003 , C09B67/0094
摘要： The invention relates to a process for preparing nondusting free-flowing pigment concentrates with removal of the water from pigment suspensions comprising polymers and dispersants in a fluidized bed drier. The resulting bead-form pigment concentrates are nondusting and readily free-flowing. The invention further embraces the use of pigment concentrates prepared in this way for coloring plastics and polymers.
摘要翻译：本发明涉及一种在流化床干燥器中从包含聚合物和分散剂的颜料悬浮液中除去水的非阻燃自由流动颜料浓缩物的方法。所得到的珠粒状颜料浓缩物是无污染的并且容易自由流动。本发明还包括以这种方式制备的颜料浓缩物用于着色塑料和聚合物的用途。

8. 发明授权

US06649421B1 Antibodies against phoshorylated VASP (vasodilator-stimulated phosphoprotein), hybridoma cells for their preparation, and their use 失效
标题翻译：针对磷酸化VASP（血管扩张剂刺激的磷蛋白）的抗体，用于其制备的杂交瘤细胞及其用途
公开(公告)号：US06649421B1
公开(公告)日：2003-11-18
申请号：US09530864
申请日：2000-06-21
申请人： Martin Eigenthaler , Heinz Hoschuetzky , Ulrich Walter
发明人： Martin Eigenthaler , Heinz Hoschuetzky , Ulrich Walter
IPC分类号： G01N33543
CPC分类号： G01N33/5008 , C07K16/18 , G01N33/502 , G01N33/5064 , G01N33/68 , G01N33/6842 , G01N33/6893 , Y10S530/866
摘要： The invention relates to antibodies against VASP (vasodilator-stimulated phosphoprotein) which only bind VASP as an antigen when VASP is present in phosphorylated form, to hybridoma cells for their preparation, and to the use of the antibodies or antibody fragments as diagnostic agents and/or therapeutic agents.
摘要翻译：本发明涉及当VASP以磷酸化形式存在时，VASP（血管扩张剂刺激的磷蛋白）仅结合VASP作为抗原的抗体，用于其制备的杂交瘤细胞，以及抗体或抗体片段用作诊断剂和/ 或治疗剂。

9. 发明授权

US5625056A Derivatives of cyclic guanosine-3',5'-monophosphorothioate 失效
标题翻译：环鸟苷-3'，5'-单磷酸硫酸酯的衍生物
公开(公告)号：US5625056A
公开(公告)日：1997-04-29
申请号：US511664
申请日：1995-08-07
申请人： Hans-Gottfried Genieser , Ulrich Walter , Elke Butt
发明人： Hans-Gottfried Genieser , Ulrich Walter , Elke Butt
IPC分类号： C07H19/20 , C07H19/213
CPC分类号： C07H19/20
摘要： New derivatives of S.sub.P - and R.sub.P -configures cyclic guanosine-3',5'-phosphorothioates and their physiologically and pharmaceutically acceptable salts according to the general formula ##STR1## are cell membrane permeable inhibitors (R.sub.P -isomers) and stimulators (S.sub.P -isomers) of cyclic GMP-dependent protein kinase which are resistant against phosphodiesterase degradation and suitable as ligands for affinity chromatography of cyclic nucleotide-dependent binding proteins.
摘要翻译： SP-和RP的新衍生物配置环鸟嘌呤-3'，5'-硫代磷酸酯及其根据通式的生理和药学上可接受的盐是细胞膜可渗透抑制剂（RP-异构体）和刺激剂（SP- 异构体）具有抗磷酸二酯酶降解的环GMP依赖性蛋白激酶，并且适合作为环核苷酸依赖性结合蛋白的亲和层析的配体。

10. 发明授权

US07563582B2 Process for screening chemical compounds for modulating the interaction of an EVH1 domain and a process for detecting said interaction 失效
标题翻译：用于筛选化合物以调节EVH1结构域的相互作用和用于检测所述相互作用的方法的方法
公开(公告)号：US07563582B2
公开(公告)日：2009-07-21
申请号：US09989188
申请日：2001-11-21
申请人： Birgit Jordan , Peter Drückes , Thomas Jarchau , Ulrich Walter
发明人： Birgit Jordan , Peter Drückes , Thomas Jarchau , Ulrich Walter
IPC分类号： G01N33/53 , G01N33/535
CPC分类号： G01N33/6845 , G01N33/542 , G01N33/574 , G01N2500/00
摘要： The invention relates to processes for identifying chemical compounds which are capable of modulating the interaction between VASP and zyxin. VASP or a VASP derivative and zyxin or a zyxin derivative which interact with one another are brought into contact with a chemical compound to be examined. The effect on the interaction can be determined using antibodies against VASP or a VASP derivative and/or zyxin or a zyxin derivative, or with the aid of fluorescent labels on VASP or a VASP derivative and zyxin or a zyxin derivative.
摘要翻译：本发明涉及鉴定化合物的方法，该化合物能够调节VASP和zyxin之间的相互作用。使彼此相互作用的VASP或VASP衍生物和zyxin或zyxin衍生物与待检查的化合物接触。可以使用针对VASP或VASP衍生物和/或zyxin或zyxin衍生物的抗体或借助于VASP或VASP衍生物和zyxin或zyxin衍生物上的荧光标记来确定对相互作用的影响。

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