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    • 1. 发明申请
    • Method and device for genetic map construction, method and device for haplotype analysis
    • 用于遗传图谱构建的方法和装置,用于单倍型分析的方法和装置
    • US20140194300A1
    • 2014-07-10
    • US14240955
    • 2012-08-24
    • Luting SongDi ShaoZequn ZhengZhijun ZhengKui WuShuheng LiangYe TaoYong Hou
    • Luting SongDi ShaoZequn ZhengZhijun ZhengKui WuShuheng LiangYe TaoYong Hou
    • C12Q1/68
    • C12Q1/6869C12Q1/6874C12Q1/6881C12Q2600/172G06F19/20G06F19/22
    • Provided are the method and device for genetic map construction and the method and device for haplotype determination of a single cell. Wherein the method for genetic map construction includes: whole genome sequencing for at least a single cell from a same species, aligning the sequencing data to reference sequences respectively to determine genotypes of SNP sites, determining male parent a/female parent b typing results of SNP genotypes of a single cell based on the genotypes of SNP sites, dividing the chromosome of the species into linkage regions based on the male parent a/female parent b typing results of SNP genotypes, determining the variation ratio of a/b between two linkage regions to obtain recombination rate between every two continuous linkage regions, determining recombination map of a single cell according to the recombination rate, wherein the boundary site of a and b is the recombination site, determining the recombination rate of each recombination rate based on the recombination map to construct a genetic map of the species.
    • 提供遗传图谱构建的方法和装置以及单细胞单体型确定的方法和装置。 遗传图谱构建方法包括:对同一物种的至少一个细胞进行全基因组测序,分别将测序数据与参照序列进行比对,以确定SNP位点的基因型,确定SNP的雄性亲本a /雌性亲本B分型结果 基于SNP位点基因型的单细胞基因型,根据SNP基因型的雄性亲本a /雌性亲本B分型结果将该物种的染色体分为连锁区,确定两个连锁区之间a / b的变异比 以获得每两个连续连锁区域之间的重组率,根据复合率确定单个细胞的重组图谱,其中a和b的边界位点是重组位点,基于重组图确定每个重组速率的重组率 构建该物种的遗传图谱。
    • 2. 发明授权
    • Method and device for genetic map construction, method and device for haplotype analysis
    • 用于遗传图谱构建的方法和装置,用于单倍型分析的方法和装置
    • US09309570B2
    • 2016-04-12
    • US14240955
    • 2012-08-24
    • Luting SongDi ShaoZequn ZhengZhijun ZhengKui WuShuheng LiangYe TaoYong Hou
    • Luting SongDi ShaoZequn ZhengZhijun ZhengKui WuShuheng LiangYe TaoYong Hou
    • C12Q1/68C12M1/34G01N33/48G06F19/20G06F19/22
    • C12Q1/6869C12Q1/6874C12Q1/6881C12Q2600/172G06F19/20G06F19/22
    • Provided are the method and device for genetic map construction and the method and device for haplotype determination of a single cell. Wherein the method for genetic map construction includes: whole genome sequencing for at least a single cell from a same species, aligning the sequencing data to reference sequences respectively to determine genotypes of SNP sites, determining male parent a/female parent b typing results of SNP genotypes of a single cell based on the genotypes of SNP sites, dividing the chromosome of the species into linkage regions based on the male parent a/female parent b typing results of SNP genotypes, determining the variation ratio of a/b between two linkage regions to obtain recombination rate between every two continuous linkage regions, determining recombination map of a single cell according to the recombination rate, wherein the boundary site of a and b is the recombination site, determining the recombination rate of each recombination rate based on the recombination map to construct a genetic map of the species.
    • 提供遗传图谱构建的方法和装置以及单细胞单体型确定的方法和装置。 遗传图谱构建方法包括:对同一物种的至少一个细胞进行全基因组测序,分别将测序数据与参照序列进行比对,以确定SNP位点的基因型,确定SNP的雄性亲本a /雌性亲本B分型结果 基于SNP位点基因型的单细胞基因型,根据SNP基因型的雄性亲本a /雌性亲本B分型结果将该物种的染色体分为连锁区,确定两个连锁区之间a / b的变异比 以获得每两个连续连锁区域之间的重组率,根据复合率确定单个细胞的重组图谱,其中a和b的边界位点是重组位点,基于重组图确定每个重组速率的重组率 构建该物种的遗传图谱。
    • 3. 发明申请
    • SECONDARY LOAD PATH FOR GAS TURBINE ENGINE
    • 用于气体涡轮发动机的二次负载路径
    • US20140061426A1
    • 2014-03-06
    • US13600645
    • 2012-08-31
    • Zhijun ZhengDavid F. Sandy
    • Zhijun ZhengDavid F. Sandy
    • B64D29/00
    • B64D27/26B64D2027/266Y02T50/44
    • A waiting link to support an engine on an aircraft includes a body portion including a first body portion opening, a second body portion opening, and a space therebetween. A first bearing is received in the first body portion opening and moveable in a generally vertical direction. A second bearing is received in the second body portion opening. The first and second bearings include a first and second bearing opening, respectively, that receives a first and second attachment member, respectively, that secures the body portion to a first and second structure, respectively. A cam is located in the space. The cam is pivotable between a first position and a second position. The waiting link does not provide a load path when the cam is in the first position, and when a primary load path fails, the waiting link provides the load path when the cam is in the second position.
    • 用于支撑飞机上的发动机的等待连接器包括主体部分,其包括第一主体部分开口,第二主体部分开口以及它们之间的空间。 第一轴承被容纳在第一主体部分中,并且在大致垂直的方向上可移动。 第二轴承被容纳在第二主体部分开口中。 第一和第二轴承分别包括第一和第二轴承开口,第一和第二轴承开口分别容纳分别将主体部分固定到第一和第二结构的第一和第二附接构件。 一个凸轮位于空间中。 凸轮可在第一位置和第二位置之间枢转。 当凸轮处于第一位置时,等待链接不提供负载路径,当主负载路径发生故障时,当凸轮处于第二位置时,等待连​​接提供负载路径。
    • 6. 发明授权
    • Assembly for mounting a turbine engine to a pylon
    • 用于将涡轮发动机安装到塔架的组件
    • US08985509B2
    • 2015-03-24
    • US13601395
    • 2012-08-31
    • David F. SandyZhijun ZhengStephen P. DaileyJoseph P. Foster
    • David F. SandyZhijun ZhengStephen P. DaileyJoseph P. Foster
    • B64D27/10B64D27/26F02C7/20F02K3/06
    • B64D27/26B64D2027/266B64D2027/268F02C7/20F02K3/06
    • An assembly for mounting a turbine engine to a pylon includes a mounting beam, a plurality of fasteners, a first mounting linkage and a second mounting linkage. The mounting beam includes a mount beam fitting that extends axially between a first mount beam end and a second mount beam end, and a mount beam flange that extends radially out from the mount beam fitting at the first mount beam end. A first fastener aperture extends radially through the mount beam fitting, and a second fastener aperture extends axially through the mount beam flange. The fasteners connect the mounting beam to the pylon. A first of the fasteners is mated with the first fastener aperture, and a second of the fasteners is mated with the second fastener aperture. The first mounting linkage connects the first mount beam end to a first engine attachment. The second mounting linkage connects the second mount beam end to second engine attachments.
    • 用于将涡轮发动机安装到塔架的组件包括安装梁,多个紧固件,第一安装连杆和第二安装连杆。 安装梁包括在第一安装梁端部和第二安装梁端部之间轴向延伸的安装梁配件以及从第一安装梁端部处的安装梁配件径向向外延伸的安装梁凸缘。 第一紧固件孔口径向延伸穿过安装梁配件,并且第二紧固件孔口轴向延伸穿过安装梁凸缘。 紧固件将安装梁连接到塔架。 紧固件中的第一紧固件与第一紧固件孔口配合,并且第二紧固件与第二紧固件孔口配合。 第一安装连杆将第一安装梁端连接到第一引擎附件。 第二安装联动装置将第二安装梁端部连接到第二发动机附件。
    • 10. 发明授权
    • Secondary load path for gas turbine engine
    • 燃气轮机的二次负荷路径
    • US09227734B2
    • 2016-01-05
    • US13600645
    • 2012-08-31
    • Zhijun ZhengDavid F. Sandy
    • Zhijun ZhengDavid F. Sandy
    • B64D27/00B64D27/26
    • B64D27/26B64D2027/266Y02T50/44
    • A waiting link to support an engine on an aircraft includes a body portion including a first body portion opening, a second body portion opening, and a space therebetween. A first bearing is received in the first body portion opening and moveable in a generally vertical direction. A second bearing is received in the second body portion opening. The first and second bearings include a first and second bearing opening, respectively, that receives a first and second attachment member, respectively, that secures the body portion to a first and second structure, respectively. A cam is located in the space. The cam is pivotable between a first position and a second position. The waiting link does not provide a load path when the cam is in the first position, and when a primary load path fails, the waiting link provides the load path when the cam is in the second position.
    • 用于支撑飞机上的发动机的等待连接器包括主体部分,其包括第一主体部分开口,第二主体部分开口以及它们之间的空间。 第一轴承被容纳在第一主体部分中,并且在大致垂直的方向上可移动。 第二轴承被容纳在第二主体部分开口中。 第一和第二轴承分别包括第一和第二轴承开口,第一和第二轴承开口分别容纳分别将主体部分固定到第一和第二结构的第一和第二附接构件。 一个凸轮位于空间中。 凸轮可在第一位置和第二位置之间枢转。 当凸轮处于第一位置时,等待链接不提供负载路径,当主负载路径发生故障时,当凸轮处于第二位置时,等待连​​接提供负载路径。